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MATVRFSGVTKAYGSTSVVSDLDLELPDGSLSVLVGPSGCGKSTTLRMLAGLETVTSGTITIGDRDVTHL QPRDRDIAMVFQNYALYPHLTVAENIAFPLRANKTPRREALARAATVAESLGLSALLGRKPKDLSGGQQQ RVAIGRAIIREPSVFLFDEPLSNLDAKLRVETRTELAQIQRRLGITSVYVTHDQEEAMTLSDRMIVMRDG KIAQQGAPQDVYARPADTFVAAFVGSPKMNLLEGTLTGGTFTLANGFALPIDEGATDGPLTLGVRPDDLL PTVGAADAPARVALIEHLGPRAIVTVDARGTELTSVVDTARLSGITEGTGVELAVRQGATHLFDTTTGRR IAGETR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3778 | - | - | 100% (356) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3854 | - | 3e-76 | 55.69% (255) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_1083 | - | 2e-67 | 43.03% (337) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2064c | - | 2e-84 | 48.20% (361) | sugar-transport ATP-binding protein ABC transporter |
| M. tuberculosis H37Rv | Rv2038c | - | 2e-84 | 48.20% (361) | sugar-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01424 | - | 1e-83 | 46.24% (359) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1375 | - | 8e-84 | 45.19% (385) | sugar ABC transporter, ATP-binding protein SugC |
| M. marinum M | MMAR_1901 | - | 3e-85 | 48.75% (361) | ABC-type sugar transport protein, ATPase component |
| M. avium 104 | MAV_2479 | - | 5e-85 | 48.61% (360) | glycerol-phosphate porter |
| M. smegmatis MC2 155 | MSMEG_3108 | - | 1e-131 | 69.66% (356) | ABC transporter, ATPase subunit |
| M. thermoresistible (build 8) | TH_4034 | - | 4e-79 | 44.73% (389) | PUTATIVE ABC transporter, ATP-binding protein SugC |
| M. ulcerans Agy99 | MUL_2252 | - | 3e-84 | 48.61% (360) | sugar-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2621 | - | 1e-171 | 85.27% (353) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2064c|M.bovis_AF2122/97 --MASVSFEQATRRYPGTD---RPALDRLDLIVGDGEFVVLVGPSGCGKT
Rv2038c|M.tuberculosis_H37Rv --MASVSFEQATRRYPGTD---RPALDRLDLIVGDGEFVVLVGPSGCGKT
MUL_2252|M.ulcerans_Agy99 --MASVSFEGATRRYPGAD---RPAVDSLDLVVDDGEFVVLVGPSGCGKT
MLBr_01424|M.leprae_Br4923 --MASVTFEQATRQFPDTD---RPALDRLDLDVDDGEFVVVVGPSGCGKT
MAV_2479|M.avium_104 MSMASVTFQQATRRYPGAD---RPALDNLNLVVGDGEFVVLVGPSGCGKT
MMAR_1901|M.marinum_M --MAKVQYSGVTYRYPGSG---APAVNNLDLEIADGEFLVLVGPSGCGKS
MAB_1375|M.abscessus_ATCC_1997 --MAEIVLNQVSKTYTDGS----AAVRDVSLNIADGEFIILVGPSGCGKS
TH_4034|M.thermoresistible__bu --MAEIVLDKVTKSYPDGAGGVRHAVKDLSLTIADGEFIILVGPSGCGKS
Mflv_3778|M.gilvum_PYR-GCK --MATVRFSGVTKAYGSTS-----VVSDLDLELPDGSLSVLVGPSGCGKS
Mvan_2621|M.vanbaalenii_PYR-1 --MATVRFSGVNKAYGTTS-----VVSDLDLELPDGSFTVLVGPSGCGKS
MSMEG_3108|M.smegmatis_MC2_155 --MASVTFSKVEKSYGAVT-----VVKDLDLELADGSLTVLVGPSGCGKT
** : . . : .: :.* : **.: ::********:
Mb2064c|M.bovis_AF2122/97 TSLRMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVA
Rv2038c|M.tuberculosis_H37Rv TSLRMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVA
MUL_2252|M.ulcerans_Agy99 TSLRMLAGLEKVDAGRIRIAERDVTNVDPKSRDVAMVFQNYALYPHMTVA
MLBr_01424|M.leprae_Br4923 TSLRMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQNYALYPHMTVA
MAV_2479|M.avium_104 TSLRMVAGLETVDSGRILIGDRDVTNVDPKQRDVAMVFQNYALYPHMTVA
MMAR_1901|M.marinum_M TILRVLAGLESVESGRITIGDTDVTDLPPRARDVAMVFQNYALYPNMTVA
MAB_1375|M.abscessus_ATCC_1997 TTLNMIAGLEDISSGELTIAGERVNEKAPKDRDIAMVFQSYALYPHMTVR
TH_4034|M.thermoresistible__bu TTLNMIAGLEDITSGEIRIDGERVNEVAPKDRDIAMVFQSYALYPHMTVR
Mflv_3778|M.gilvum_PYR-GCK TTLRMLAGLETVTSGTITIGDRDVTHLQPRDRDIAMVFQNYALYPHLTVA
Mvan_2621|M.vanbaalenii_PYR-1 TSLRMLAGLETVTSGSITIGARDVTHLQPRDRDIAMVFQNYALYPHLTVA
MSMEG_3108|M.smegmatis_MC2_155 TSLRMLAGLEPVTSGTIHIGDRDVTRLEPRDRDIAMVFQNYALYPHLTVR
* *.::**** : .* : * *. *: **:*****.*****::**
Mb2064c|M.bovis_AF2122/97 QNMGFALKVAKIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVA
Rv2038c|M.tuberculosis_H37Rv QNMGFALKVAKIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVA
MUL_2252|M.ulcerans_Agy99 QNMGFALKVAKTPKAEIRDRVLQAAKLLDLEAYLDRKPKDLSGGQRQRVA
MLBr_01424|M.leprae_Br4923 QNLGFALKISKISKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVA
MAV_2479|M.avium_104 QNMGFAMKIAKTPKAQIRERVLDAAKLLDLQPYLDRKPKDLSGGQRQRVA
MMAR_1901|M.marinum_M QNMGFALRNAGMSRADTRQRVLEVASMLELTELLDRKPSKLSGGQRQRVA
MAB_1375|M.abscessus_ATCC_1997 QNIAFPLTLAKMSKDDINAKVAEAAKILDLTDYLDRKPANLSGGQRQRVA
TH_4034|M.thermoresistible__bu QNIAFPLTLAKMKKADIARKVEETAKILDLTELLDRKPAQLSGGQRQRVA
Mflv_3778|M.gilvum_PYR-GCK ENIAFPLRANKTPRREALARAATVAESLGLSALLGRKPKDLSGGQQQRVA
Mvan_2621|M.vanbaalenii_PYR-1 ENIAFPLRATKTPRREALTRAATIAESLGLAKLLDRKPKDLSGGQQQRVA
MSMEG_3108|M.smegmatis_MC2_155 ENIAFPLRATKTPRAEALKRADDIAASLGLGALVSRKPKDLSGGQQQRVA
:*:.*.: : : : * * * :.*** .*****:****
Mb2064c|M.bovis_AF2122/97 MGRAIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHD
Rv2038c|M.tuberculosis_H37Rv MGRAIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHD
MUL_2252|M.ulcerans_Agy99 MGRAIVRRPQVFLMDEPLSNLDTKLRVQTRNQIAGLQRQLGTTTVYVTHD
MLBr_01424|M.leprae_Br4923 MGRAIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHD
MAV_2479|M.avium_104 MGRAIVRRPQVFLMDEPLSNLDAKLRVQTRNQIAALQRRLGTTTVYVTHD
MMAR_1901|M.marinum_M MGRAIVRRPRVFCMDEPLSNLDAKLRVSTRSHISGLQRQLGTTTVYVTHD
MAB_1375|M.abscessus_ATCC_1997 MGRAIVRSPKAFLMDEPLSNLDAKLRVQMRTEIARLQKRLGTTTVYVTHD
TH_4034|M.thermoresistible__bu MGRAIVRQPKAFLMDEPLSNLDAKLRVQMRSEIARLQSRLRTTTVYVTHD
Mflv_3778|M.gilvum_PYR-GCK IGRAIIREPSVFLFDEPLSNLDAKLRVETRTELAQIQRRLGITSVYVTHD
Mvan_2621|M.vanbaalenii_PYR-1 IGRAIIREPSVFLFDEPLSNLDAKLRVETRTELLQIQRRLGITSVYVTHD
MSMEG_3108|M.smegmatis_MC2_155 IGRAIIREPAVFLFDEPLSNLDAKLRVETRTELLRLQRRLGITSLYVTHD
:****:* * .* :********:*** . *..: :* :* *::*****
Mb2064c|M.bovis_AF2122/97 QVEAMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFR
Rv2038c|M.tuberculosis_H37Rv QVEAMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFR
MUL_2252|M.ulcerans_Agy99 QVEAMTMGDRVAVLCDGVLQQCAAPRELYRRPDNVFVAGFIGSPAMNMFI
MLBr_01424|M.leprae_Br4923 QVEAMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVT
MAV_2479|M.avium_104 QVEAMTMGDRVAVLRDGVLQQFAPPRELYRNPSNVFVAGFIGSPAMNLFT
MMAR_1901|M.marinum_M QVEAMTMGHRVAVLKDGVLQQVDTPRELYDNPVNTFVATFIGAPAMNLIE
MAB_1375|M.abscessus_ATCC_1997 QTEAMTLGDRVVVLRAGKVQQVGAPQELYDTPANLFVAGFIGSPSMNFFP
TH_4034|M.thermoresistible__bu QTEAMTLGDRVVVMLDGVAQQIGTPDELYTQPANLFVAGFIGSPGMNFFP
Mflv_3778|M.gilvum_PYR-GCK QEEAMTLSDRMIVMRDGKIAQQGAPQDVYARPADTFVAAFVGSPKMNLLE
Mvan_2621|M.vanbaalenii_PYR-1 QEEAMTLSDRMVVMRDGRIAQQGTPQEVYARPADTFVAAFVGSPKMNLID
MSMEG_3108|M.smegmatis_MC2_155 QEEAMTLSDRIVVMRDGQIAQAGPPEEVYRRPADTFVATFVGSPKMNLVD
* ****:..*: *: * * .* ::* * : *** *:*:* **:.
Mb2064c|M.bovis_AF2122/97 LSIADSTVSLGDWQILLPRAVVGTAAE------VIIGVRPEHLELGG---
Rv2038c|M.tuberculosis_H37Rv LSIADSTVSLGDWQILLPRAVVGTAAE------VIIGVRPEHLELGG---
MUL_2252|M.ulcerans_Agy99 LPIVDSSVLLGDWLIQLPREVTVPAPE------VVVGVRPEHFEVGN---
MLBr_01424|M.leprae_Br4923 LSIVDSSVLLGDWPIRIPREIASAASE------VIIGVRPEHFELGS---
MAV_2479|M.avium_104 LPVVDSAVSLGDWPIALPREIAAAASE------VVVGVRPEHFELGG---
MMAR_1901|M.marinum_M APVADGVARLSGLVIPVPR---GAADR------VLIGVRPESWDVVGGDA
MAB_1375|M.abscessus_ATCC_1997 ATLTDVGVQLPFGEVTLDAGLYAGITARKPSGDVIVGIRPEQFEDAALVD
TH_4034|M.thermoresistible__bu ASLTDAGVRLPFGEALLPPDVLDTVRRHEKTDNIIAGLRPEHLEDVSLLD
Mflv_3778|M.gilvum_PYR-GCK GTLTGGTFTLANG-FALPIDEGATDGP------LTLGVRPDDLLP-----
Mvan_2621|M.vanbaalenii_PYR-1 GAVSGTTFTVGDG-FALTVDQTAAGGP------VTLGVRPDDLLP-----
MSMEG_3108|M.smegmatis_MC2_155 GAVSGGELRTESG-LRIRVGG-PDAAA------VTVGVRPDDLTLRPVQT
.: . : : *:**:
Mb2064c|M.bovis_AF2122/97 -------AGIEMDVDMVEELGADAYLYGRIVSGG-------------CEM
Rv2038c|M.tuberculosis_H37Rv -------AGIEMDVDMVEELGADAYLYGRIVSGG-------------CEM
MUL_2252|M.ulcerans_Agy99 -------LGVEMEIDVVEELGADAYLYGRISNGG-------------TMI
MLBr_01424|M.leprae_Br4923 -------LGVEVEIDMVEELGADAYLYGRIAGAS-------------KVT
MAV_2479|M.avium_104 -------LGVEMEVDVVEELGADAYLYGRITGSG-------------KVI
MMAR_1901|M.marinum_M ------AAALGVRVEQVEELGFESFIYATPVAQDGW-----------SSR
MAB_1375|M.abscessus_ATCC_1997 TYKRITGLTLTVNADVVESLGSDKYVHFTTEGGAAHSDELTELAQESEVA
TH_4034|M.thermoresistible__bu TYARLGAVTFDVNVELVESLGAEKYVHFRAEGAGAHAAQLAQLAAESGAG
Mflv_3778|M.gilvum_PYR-GCK ---TVGAADAPARVALIEHLGPRAIVTVDA-----------------RGT
Mvan_2621|M.vanbaalenii_PYR-1 ---TVSDGDGAARVILIEHLGPRAIVTIDA-----------------RGT
MSMEG_3108|M.smegmatis_MC2_155 ---TATTASAAPTVELVELLGPRAIVTVRS-----------------GEL
:* ** :
Mb2064c|M.bovis_AF2122/97 DQSIVARVDGRGPPERGSRVRLCPTPGHLHFFA-VDGRRIPG-----
Rv2038c|M.tuberculosis_H37Rv DQSIVARVDGRGPPERGSRVRLCPTPGHLHFFA-VDGRRIPG-----
MUL_2252|M.ulcerans_Agy99 DQSVVARADGSNPPERGSRVRLYPQPAQLHFFT-VDGRRIA------
MLBr_01424|M.leprae_Br4923 DQLVVARVDGRNPPAKGSRVRLYTEPGNVHFFG-VDGHRIS------
MAV_2479|M.avium_104 DAPIVARVDGRNPPEKGSRVRLHPAPGHLHFFG-RNGQRIGVRGSW-
MMAR_1901|M.marinum_M TRRIVIRSDRHTTVGAGDSLSIAPNPQEVCFFDSRTESRIR------
MAB_1375|M.abscessus_ATCC_1997 ENEFVARLSAASKVAEGQPIELIIDTGKLVIFDAESGENLSLAATAE
TH_4034|M.thermoresistible__bu ENEFIARVSTESKAKKGQSLQLAFNPAKLLVFDADTGANLTLPPSDA
Mflv_3778|M.gilvum_PYR-GCK ELTSVVDTARLSGITEGTGVELAVRQGATHLFDTTTGRRIAGETR--
Mvan_2621|M.vanbaalenii_PYR-1 ELTSVVETSRLSGITEGTPVDLAVRPGATHFFDPATGSRLSG-----
MSMEG_3108|M.smegmatis_MC2_155 RLTSVVDAPSLSEIPTGTAVELSARD--VHRFDIATGTRLPD-----
: * : : * .: