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MTTRRKTAAVAGIAAVAIFGAACSSEGADSTASSATTTSESAMESATTAMTTSSAAPSADPAANLIGSGC AAYAEQVPDGPGSVAGMAADPVTVAASNNPMLKTLTQALSGQLNPGVNLVDTLNGGEFTVFAPTDDAFAK IDPATIETLKTDSDLLTSILTYHVVPGQAAPDQVAGEHATVQGATVTVTGAGNDLKVNEAGLVCGGVKTA NATVYMIDTVLMPPAN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2259 | - | - | 100% (227) | beta-Ig-H3/fasciclin |
| M. vanbaalenii PYR-1 | Mvan_2258 | - | 3e-75 | 76.11% (180) | beta-Ig-H3/fasciclin |
| M. vanbaalenii PYR-1 | Mvan_4586 | - | 7e-34 | 37.56% (197) | beta-Ig-H3/fasciclin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2898 | mpb83 | 2e-72 | 63.44% (227) | cell surface lipoprotein MPB83 (lipoprotein P23) |
| M. gilvum PYR-GCK | Mflv_4084 | - | 1e-111 | 88.55% (227) | beta-Ig-H3/fasciclin |
| M. tuberculosis H37Rv | Rv2873 | mpt83 | 2e-72 | 63.44% (227) | cell surface lipoprotein mpt83 (lipoprotein P23) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4543c | - | 7e-05 | 38.33% (60) | hypothetical protein MAB_4543c |
| M. marinum M | MMAR_1834 | mpt70 | 5e-70 | 68.48% (184) | major secreted immunogenic protein Mpt70 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5196 | - | 4e-30 | 37.24% (196) | fasciclin domain-containing protein |
| M. thermoresistible (build 8) | TH_1983 | - | 3e-31 | 37.20% (207) | fasciclin domain protein |
| M. ulcerans Agy99 | MUL_1162 | lpqI | 3e-05 | 48.21% (56) | lipoprotein LpqI |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2259|M.vanbaalenii_PYR-1 MMTTRRKTAAVAGIAAVAIFGAACSSEGADSTASSATTTSESAMESATTA
Mflv_4084|M.gilvum_PYR-GCK MMTTRRKTAAVAGIAAVAIFGAACSSEEAGNNASSATSSATSAMESATSE
Mb2898|M.bovis_AF2122/97 MINVQAKPAAAASLAAIAIAFLAGCS-------STKPVSQDTSPKPATSP
Rv2873|M.tuberculosis_H37Rv MINVQAKPAAAASLAAIAIAFLAGCS-------STKPVSQDTSPKPATSP
MMAR_1834|M.marinum_M -MKFHNPAIAATGLAAAAAVGLV----------------------VATAP
MSMEG_5196|M.smegmatis_MC2_155 MHTRTKTLGAAAAIAAIATSLPLAVT----------------AYAEPETT
TH_1983|M.thermoresistible__bu VQTRTKVFGAVTGAAAIAFSLPLAGT----------------AHGEPGDP
MUL_1162|M.ulcerans_Agy99 -MAFPRTLAVLAAASALVAACSHGGTRTG--SSSTTTSAGASRSATSSTP
MAB_4543c|M.abscessus_ATCC_199 -MRNRTRTAILAGAAAAVLILSACSS--------DNKGDDAKSEHSGHSG
:. :* .
Mvan_2259|M.vanbaalenii_PYR-1 MTTSSAAPSADPAAN-----------------------------------
Mflv_4084|M.gilvum_PYR-GCK MTTSSSAPMADPAAN-----------------------------------
Mb2898|M.bovis_AF2122/97 AAPVTTAAMADPAAD-----------------------------------
Rv2873|M.tuberculosis_H37Rv AAPVTTAAMADPAAD-----------------------------------
MMAR_1834|M.marinum_M SA------MASPPDT-----------------------------------
MSMEG_5196|M.smegmatis_MC2_155 TEAEP----TVEIPD-----------------------------------
TH_1983|M.thermoresistible__bu PTPAPDLMVTADIPD-----------------------------------
MUL_1162|M.ulcerans_Agy99 MAAAAPRICADPAAVPAAMPNVRDKLAQSLMVGVRDGDDARAVVTNYRVG
MAB_4543c|M.abscessus_ATCC_199 MSGMTTTLDTNAAAP-----------------------------------
:
Mvan_2259|M.vanbaalenii_PYR-1 --LIGSGCAAYAEQVPDGPGSVAGMAADPVTVAASNNP-MLKTLTQALSG
Mflv_4084|M.gilvum_PYR-GCK --LIGSGCAAYAEQVPEGPGSVAGMAADPVTVAASNNP-MLTTLTQALSG
Mb2898|M.bovis_AF2122/97 --LIGRGCAQYAAQNPTGPGSVAGMAQDPVATAASNNP-MLSTLTSALSG
Rv2873|M.tuberculosis_H37Rv --LIGRGCAQYAAQNPTGPGSVAGMAQDPVATAASNNP-MLSTLTSALSG
MMAR_1834|M.marinum_M --LVGPGCSAYAQQVPTGPGSVAGMAAEPVAVAASNNP-MLTTLTSALSG
MSMEG_5196|M.smegmatis_MC2_155 --PQGPGCDDFKKAVP----SWKALNDVPVSQALAAIP-EISTFNAAVSG
TH_1983|M.thermoresistible__bu --PEGPGCDAFKAEVS----DFKNLARVPVGDALAAIP-QISTFNSAISG
MUL_1162|M.ulcerans_Agy99 GILIGSDTDLSILTNGVLKDIVAGSGPLPVAVNVDEEGGRVSRLKSLLGG
MAB_4543c|M.abscessus_ATCC_199 --VSDHNDADVTFAQQMIMHHQQAVEMSKLTEGRTANP-AVLDLAKNIET
. . : : : :
Mvan_2259|M.vanbaalenii_PYR-1 -----------------------------------QLNPGVNLVDTLNGG
Mflv_4084|M.gilvum_PYR-GCK -----------------------------------QLNPNVNLVDTLDGA
Mb2898|M.bovis_AF2122/97 -----------------------------------KLNPDVNLVDTLNGG
Rv2873|M.tuberculosis_H37Rv -----------------------------------KLNPDVNLVDTLNGG
MMAR_1834|M.marinum_M -----------------------------------KLNPQVNLVDTLNGG
MSMEG_5196|M.smegmatis_MC2_155 -----------------------------------GLNPAVNIDPVLDNG
TH_1983|M.thermoresistible__bu -----------------------------------QLNPEVNIVPVLNNG
MUL_1162|M.ulcerans_Agy99 RGPSARELARTDTVDQVYDVALQRGRKMKELGITVDLAPVVDVTDAPDDT
MAB_4543c|M.abscessus_ATCC_199 -----------------------------------AQQPEIDTFTGWLKQ
* ::
Mvan_2259|M.vanbaalenii_PYR-1 EF--TVFAPTDDAFAKIDPATIETLKTDSDLLTSILTYHVVPGQAAPDQV
Mflv_4084|M.gilvum_PYR-GCK EF--TVFAPTDDAFAKIDPATLETLKTDNELLTSILTYHVVPGQAAPDAV
Mb2898|M.bovis_AF2122/97 EY--TVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQASPSRI
Rv2873|M.tuberculosis_H37Rv EY--TVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQASPSRI
MMAR_1834|M.marinum_M QF--TVFAPTDAAFGKIDAATIDSLKTDAPLLKKILTYHVVPGQLSPSQV
MSMEG_5196|M.smegmatis_MC2_155 PY--VVFAPTNEAFAKLAPGQLDAIAADPAALTSLDYYHAFLGLLGNDDV
TH_1983|M.thermoresistible__bu PY--VVFAPTNEAFEELPAGKLDALAADPAALTQLGYYHAFLGLLGPDTV
MUL_1162|M.ulcerans_Agy99 VIGDRSFGSNPETVTEYAGAYARGLR-DAGLLPVLKHFPGHGRASGDSHT
MAB_4543c|M.abscessus_ATCC_199 WN--QPLMPEGHDPAGHMPGMVDAPVLDRMKTLNGEVFDQLWLQSMIAHH
: . . * :
Mvan_2259|M.vanbaalenii_PYR-1 AGEHA----TVQGATVT----------------------VTGAGNDLKVN
Mflv_4084|M.gilvum_PYR-GCK AGEHT----TVQGAPLT----------------------VTGAGNDLMVN
Mb2898|M.bovis_AF2122/97 DGTHQ----TLQGADLT----------------------VIGARDDLMVN
Rv2873|M.tuberculosis_H37Rv DGTHQ----TLQGADLT----------------------VIGARDDLMVN
MMAR_1834|M.marinum_M VGTHS----TVEGASLT----------------------VTGSGNDLQVG
MSMEG_5196|M.smegmatis_MC2_155 KGQRP----TQQGAEIK----------------------VTGKGGDIEVN
TH_1983|M.thermoresistible__bu KGQRP----TQDGAEIK----------------------VTGEGGDITVN
MUL_1162|M.ulcerans_Agy99 GGVVTPPLSDLQDSDLVPYRTLVTQTPVAVMLGHLQVPGLTGDEPASLSK
MAB_4543c|M.abscessus_ATCC_199 QGAIA-----MSNAELS-------------------------GGQYPAAK
* ..: :
Mvan_2259|M.vanbaalenii_PYR-1 E-AGLVCGG-------------------VKTANATVYMIDTVLMPPAN--
Mflv_4084|M.gilvum_PYR-GCK D-AGLVCGG-------------------VKTANATVYMIDTVLMPPAN--
Mb2898|M.bovis_AF2122/97 N-AGLVCGG-------------------VHTANATVYMIDTVLMPPAQ--
Rv2873|M.tuberculosis_H37Rv N-AGLVCGG-------------------VHTANATVYMIDTVLMPPAQ--
MMAR_1834|M.marinum_M D-AAVVCGG-------------------VQTANAVVYMIDTVLMPPS---
MSMEG_5196|M.smegmatis_MC2_155 DTAKLVCGA-------------------IHAQNARIYLIDTVLDPNNPPE
TH_1983|M.thermoresistible__bu DTAEVVCGG-------------------IQAANARIYLIDKVLDPAQAPD
MUL_1162|M.ulcerans_Agy99 NAVDLLRNGTGYGGPPFDGPIFSDDLSSMAAISDRYGVTEAVLRSLQAGT
MAB_4543c|M.abscessus_ATCC_199 QLAQQIIDN----------------------QQPEIDTMQGLLKG-----
: . : . . : :*
Mvan_2259|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4084|M.gilvum_PYR-GCK --------------------------------------------------
Mb2898|M.bovis_AF2122/97 --------------------------------------------------
Rv2873|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1834|M.marinum_M --------------------------------------------------
MSMEG_5196|M.smegmatis_MC2_155 ALTPTVSGTSTTPTTTTETTEPAPAEAPESAETPEAMPAADAPIG-----
TH_1983|M.thermoresistible__bu PITP---GSSSTNSSSDSSDSSGSSDSSE-----QALPAEDPTA------
MUL_1162|M.ulcerans_Agy99 DIALWVSTEEVPAVLDRLEQALAAGELQMSAVDASLVRVARMKNVSASCG
MAB_4543c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2259|M.vanbaalenii_PYR-1 -
Mflv_4084|M.gilvum_PYR-GCK -
Mb2898|M.bovis_AF2122/97 -
Rv2873|M.tuberculosis_H37Rv -
MMAR_1834|M.marinum_M -
MSMEG_5196|M.smegmatis_MC2_155 -
TH_1983|M.thermoresistible__bu -
MUL_1162|M.ulcerans_Agy99 H
MAB_4543c|M.abscessus_ATCC_199 -