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MRVLDLAVTNSCTYHARRLDKRKEHTVKTRTSKAIGVAVSAAAIALSVPLAINAHAEPSTPVAEIPDPQG PDCGAFKEALPNWKGLANLPVSTALSSIPDISSFNSAISGQLNPAVNITGVLDNGPYVVFAPTNEAFAAL PPEQLEVLRTDPAALTSLVYYHVFLGLLGPDDVKGQRPTQQGTEIEVTGSGGDIAVNETTKVVCGGIQAQ NARIYIVDQVLNPAEAPAPITPTSTSETSSTETTTPTTPTSTETPPPAPAEAPTVPAAEAPIG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4586 | - | - | 100% (273) | beta-Ig-H3/fasciclin |
| M. vanbaalenii PYR-1 | Mvan_2258 | - | 5e-36 | 40.49% (205) | beta-Ig-H3/fasciclin |
| M. vanbaalenii PYR-1 | Mvan_2259 | - | 9e-34 | 37.56% (197) | beta-Ig-H3/fasciclin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2900 | mpb70 | 2e-33 | 37.81% (201) | major secreted immunogenic protein mpb70 precursor |
| M. gilvum PYR-GCK | Mflv_2119 | - | 1e-112 | 78.95% (247) | beta-Ig-H3/fasciclin |
| M. tuberculosis H37Rv | Rv2875 | mpt70 | 2e-33 | 37.81% (201) | major secreted immunogenic protein MPT70 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1835c | - | 5e-05 | 40.38% (52) | immunogenic protein MPT64 precursor |
| M. marinum M | MMAR_1834 | mpt70 | 5e-32 | 39.18% (194) | major secreted immunogenic protein Mpt70 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5196 | - | 2e-85 | 63.81% (257) | fasciclin domain-containing protein |
| M. thermoresistible (build 8) | TH_1983 | - | 2e-78 | 60.32% (247) | fasciclin domain protein |
| M. ulcerans Agy99 | MUL_0583 | - | 6e-05 | 46.34% (41) | hypothetical protein MUL_0583 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2900|M.bovis_AF2122/97 ---------------------------MKVKN-TIAATSFAAAGLAALAV
Rv2875|M.tuberculosis_H37Rv ---------------------------MKVKN-TIAATSFAAAGLAALAV
MMAR_1834|M.marinum_M ---------------------------MKFHNPAIAATGLAAAAAVGLVV
Mvan_4586|M.vanbaalenii_PYR-1 MRVLDLAVTNSCTYHARRLDKRKEHTVKTRTSKAIGVAVSAAAIALSVPL
Mflv_2119|M.gilvum_PYR-GCK --------------------------MKTRTSKAVGAALGVAAIALSVPL
MSMEG_5196|M.smegmatis_MC2_155 --------------------------MHTRT-KTLGAAAAIAAIATSLPL
TH_1983|M.thermoresistible__bu --------------------------VQTRT-KVFGAVTGAAAIAFSLPL
MUL_0583|M.ulcerans_Agy99 -------------------------------------------------M
MAB_1835c|M.abscessus_ATCC_199 ------------------------MPYLSLRSISASVLVTAASIFGFSGV
:
Mb2900|M.bovis_AF2122/97 AVSPPAAAG----------------DLVGPGCAEYAAANPTGPASVQGMS
Rv2875|M.tuberculosis_H37Rv AVSPPAAAG----------------DLVGPGCAEYAAANPTGPASVQGMS
MMAR_1834|M.marinum_M ATAPSAMASPP-------------DTLVGPGCSAYAQQVPTGPGSVAGMA
Mvan_4586|M.vanbaalenii_PYR-1 AINAHAEPSTP---------VAEIPDPQGPDCGAFKEALP----NWKGLA
Mflv_2119|M.gilvum_PYR-GCK AVNASAEPSTP---------TVEVPDPQGPDCGPFKEAVP----EWKGLA
MSMEG_5196|M.smegmatis_MC2_155 AVTAYAEPETTTEAEP----TVEIPDPQGPGCDDFKKAVP----SWKALN
TH_1983|M.thermoresistible__bu AGTAHGEPGDPPTPAPDLMVTADIPDPEGPGCDAFKAEVS----DFKNLA
MUL_0583|M.ulcerans_Agy99 ARHDPPDYGAG--------------DPTAYGNYGYGDQRG----GYGQQP
MAB_1835c|M.abscessus_ATCC_199 AGAAPHDYCGDLKGTN-----TGKTCEIRLSDTGYSVDVTIP-LNYPDQK
* . :
Mb2900|M.bovis_AF2122/97 QDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAF
Rv2875|M.tuberculosis_H37Rv QDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAF
MMAR_1834|M.marinum_M AEPVAVAASNNPMLTTLTSALSGKLNPQVNLVDTLNGGQFTVFAPTDAAF
Mvan_4586|M.vanbaalenii_PYR-1 NLPVSTALSSIPDISSFNSAISGQLNPAVNITGVLDNGPYVVFAPTNEAF
Mflv_2119|M.gilvum_PYR-GCK NLPVSTALASIPEISTFTSAISGQLNPAVNITGVLDNGPYVVFAPTNEAF
MSMEG_5196|M.smegmatis_MC2_155 DVPVSQALAAIPEISTFNAAVSGGLNPAVNIDPVLDNGPYVVFAPTNEAF
TH_1983|M.thermoresistible__bu RVPVGDALAAIPQISTFNSAISGQLNPEVNIVPVLNNGPYVVFAPTNEAF
MUL_0583|M.ulcerans_Agy99 PPEPTPGWRKPLALAGWGVLIAVLIGLIIFGIIQLAHGRPTPASVTKTVT
MAB_1835c|M.abscessus_ATCC_199 SIAEYVAKTRDAFVNAAKSGAARSTTAQLSMKPTEYNSDLPPRGTQTVVF
. : : : . . .
Mb2900|M.bovis_AF2122/97 SKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVG----------TR
Rv2875|M.tuberculosis_H37Rv SKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVG----------TR
MMAR_1834|M.marinum_M GKIDAATIDSLKTDAPLLKKILTYHVVPGQLSPSQVVG----------TH
Mvan_4586|M.vanbaalenii_PYR-1 AALPPEQLEVLRTDPAALTSLVYYHVFLGLLGPDDVKG----------QR
Mflv_2119|M.gilvum_PYR-GCK AALPPEQLEILRTDPAALTTLVYYHAFLGLLGPDDVKG----------QR
MSMEG_5196|M.smegmatis_MC2_155 AKLAPGQLDAIAADPAALTSLDYYHAFLGLLGNDDVKG----------QR
TH_1983|M.thermoresistible__bu EELPAGKLDALAADPAALTQLGYYHAFLGLLGPDTVKG----------QR
MUL_0583|M.ulcerans_Agy99 ATMTTTTPTTTTAPTKTTTTTTTTTTTTTTTTTTTTTT----------TT
MAB_1835c|M.abscessus_ATCC_199 KVYQTGGNGQPQTAYKAFNWDQSYRKPVLYTVPKDDKDDAPLWRVDDPLK
. : .
Mb2900|M.bovis_AF2122/97 QTLQGASVTVTGQGNSLKVGN-ADVVCGGVSTANATVY-MIDSVLMPPA-
Rv2875|M.tuberculosis_H37Rv QTLQGASVTVTGQGNSLKVGN-ADVVCGGVSTANATVY-MIDSVLMPPA-
MMAR_1834|M.marinum_M STVEGASLTVTGSGNDLQVGD-AAVVCGGVQTANAVVY-MIDTVLMPPS-
Mvan_4586|M.vanbaalenii_PYR-1 PTQQGTEIEVTGSGGDIAVNETTKVVCGGIQAQNARIY-IVDQVLNPAEA
Mflv_2119|M.gilvum_PYR-GCK PTQEGTEVEVTGSGGDIQVNATTKVVCGGITAQNAKVY-IIDQVLNPAEA
MSMEG_5196|M.smegmatis_MC2_155 PTQQGAEIKVTGKGGDIEVNDTAKLVCGAIHAQNARIY-LIDTVLDPNNP
TH_1983|M.thermoresistible__bu PTQDGAEIKVTGEGGDITVNDTAEVVCGGIQAANARIY-LIDKVLDPAQA
MUL_0583|M.ulcerans_Agy99 TTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFPSQLTPSIPTVINLPPG
MAB_1835c|M.abscessus_ATCC_199 TVAPIVQAQLQQQLAPPPVATPTPTTTSGQPTTTTSTT-TTSTTPPPPPP
. . . .. : : .
Mb2900|M.bovis_AF2122/97 --------------------------------------------------
Rv2875|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1834|M.marinum_M --------------------------------------------------
Mvan_4586|M.vanbaalenii_PYR-1 PAPITPTSTSETSSTETTTPTTPTSTETPPPAPAEAPTVPAAEAPIG---
Mflv_2119|M.gilvum_PYR-GCK PAPIAPTSTSTTETTTTGSAEASTSATAPAETTEPAAPSPAAEAPAG---
MSMEG_5196|M.smegmatis_MC2_155 PEALTPTVSGTSTTPTTTTETTEPAPAEAPESAETPEAMPAADAPIG---
TH_1983|M.thermoresistible__bu PDPITP---GSSSTNSSSDSSDSSGSSDSSE-----QALPAEDPTA----
MUL_0583|M.ulcerans_Agy99 L-------------------------------------------------
MAB_1835c|M.abscessus_ATCC_199 PLPFSPATLYDPANYQNFAVLNDGIRFFFDQGAILPDSYGALQVLVPRSA
Mb2900|M.bovis_AF2122/97 ------
Rv2875|M.tuberculosis_H37Rv ------
MMAR_1834|M.marinum_M ------
Mvan_4586|M.vanbaalenii_PYR-1 ------
Mflv_2119|M.gilvum_PYR-GCK ------
MSMEG_5196|M.smegmatis_MC2_155 ------
TH_1983|M.thermoresistible__bu ------
MUL_0583|M.ulcerans_Agy99 ------
MAB_1835c|M.abscessus_ATCC_199 IDPMIA