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M. marinum M MMAR_1834 (mpt70)

annotation: major secreted immunogenic protein Mpt70
coordinates: 2232872 - 2233465
length: 197

KFHNPAIAATGLAAAAAVGLVVATAPSAMASPPDTLVGPGCSAYAQQVPTGPGSVAGMAAEPVAVAASNN
PMLTTLTSALSGKLNPQVNLVDTLNGGQFTVFAPTDAAFGKIDAATIDSLKTDAPLLKKILTYHVVPGQL
SPSQVVGTHSTVEGASLTVTGSGNDLQVGDAAVVCGGVQTANAVVYMIDTVLMPPS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1834mpt70-100% (197)major secreted immunogenic protein Mpt70

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2900mpb701e-6867.51% (197) major secreted immunogenic protein mpb70 precursor
M. gilvum PYR-GCKMflv_4084-2e-7066.84% (196) beta-Ig-H3/fasciclin
M. tuberculosis H37RvRv2875mpt701e-6867.51% (197) major secreted immunogenic protein MPT70
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_5196-4e-2835.86% (198) fasciclin domain-containing protein
M. thermoresistible (build 8)TH_1983-1e-3341.00% (200) fasciclin domain protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2258-6e-7369.63% (191) beta-Ig-H3/fasciclin

CLUSTAL 2.0.9 multiple sequence alignment


Mb2900|M.bovis_AF2122/97            -MKVKN-TIAATSFAAAGLAALAVAV------------------------
Rv2875|M.tuberculosis_H37Rv         -MKVKN-TIAATSFAAAGLAALAVAV------------------------
Mflv_4084|M.gilvum_PYR-GCK          MMTTRRKTAAVAGIAAVAIFGAACSSEEAGNNASSATSSATSAMESATSE
Mvan_2258|M.vanbaalenii_PYR-1       -MTVTMKSLVGAGFAVTAAVGLSFGT--AG--------------------
MMAR_1834|M.marinum_M               -MKFHNPAIAATGLAAAAAVGLVVAT--AP--------------------
MSMEG_5196|M.smegmatis_MC2_155      -MHTRTKTLGAAAAIAAIATSLPLAVTAYAE-------------------
TH_1983|M.thermoresistible__bu      -VQTRTKVFGAVTGAAAIAFSLPLAGTAHGE-------------------
                                     :         .   ..   .   .                         

Mb2900|M.bovis_AF2122/97            ------SPPAAAG--------DLVGPGCAEYAAANPTGPASVQGMSQDPV
Rv2875|M.tuberculosis_H37Rv         ------SPPAAAG--------DLVGPGCAEYAAANPTGPASVQGMSQDPV
Mflv_4084|M.gilvum_PYR-GCK          MTTSSSAPMADPAA-------NLIGSGCAAYAEQVPEGPGSVAGMAADPV
Mvan_2258|M.vanbaalenii_PYR-1       ------TAWAEP-----------VGPGCAAYVQQVPEGPGSVQGMAASPV
MMAR_1834|M.marinum_M               ------SAMASPPD-------TLVGPGCSAYAQQVPTGPGSVAGMAAEPV
MSMEG_5196|M.smegmatis_MC2_155      ---PETTTEAEP----TVEIPDPQGPGCDDFKKAVP----SWKALNDVPV
TH_1983|M.thermoresistible__bu      ---PGDPPTPAPDLMVTADIPDPEGPGCDAFKAEVS----DFKNLARVPV
                                          .. . .            *.**  :    .    .   :   **

Mb2900|M.bovis_AF2122/97            AVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLP
Rv2875|M.tuberculosis_H37Rv         AVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLP
Mflv_4084|M.gilvum_PYR-GCK          TVAASNNPMLTTLTQALSGQLNPNVNLVDTLDGAEFTVFAPTDDAFAKID
Mvan_2258|M.vanbaalenii_PYR-1       ATAAADNPLLTTLTKAVSGQLNPHVNLVDTLNGGEFTVFAPTDAAFAKID
MMAR_1834|M.marinum_M               AVAASNNPMLTTLTSALSGKLNPQVNLVDTLNGGQFTVFAPTDAAFGKID
MSMEG_5196|M.smegmatis_MC2_155      SQALAAIPEISTFNAAVSGGLNPAVNIDPVLDNGPYVVFAPTNEAFAKLA
TH_1983|M.thermoresistible__bu      GDALAAIPQISTFNSAISGQLNPEVNIVPVLNNGPYVVFAPTNEAFEELP
                                      * :  * ::*:. *:** *** **:  .*:.. :.*****: ** :: 

Mb2900|M.bovis_AF2122/97            ASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQG
Rv2875|M.tuberculosis_H37Rv         ASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQG
Mflv_4084|M.gilvum_PYR-GCK          PATLETLKTDNELLTSILTYHVVPGQAAPDAVAGEHTTVQGAPLTVTGAG
Mvan_2258|M.vanbaalenii_PYR-1       PATIETLKTDSDLLTNILTYHVVPGQAAPEQVVGEHVTVQGGTVNVTGAG
MMAR_1834|M.marinum_M               AATIDSLKTDAPLLKKILTYHVVPGQLSPSQVVGTHSTVEGASLTVTGSG
MSMEG_5196|M.smegmatis_MC2_155      PGQLDAIAADPAALTSLDYYHAFLGLLGNDDVKGQRPTQQGAEIKVTGKG
TH_1983|M.thermoresistible__bu      AGKLDALAADPAALTQLGYYHAFLGLLGPDTVKGQRPTQDGAEIKVTGEG
                                    .. :: : ::   *..:  **.. *  .   * * : * :*. :.*** *

Mb2900|M.bovis_AF2122/97            NSLKVGN-ADVVCGGVSTANATVYMIDSVLMP------------------
Rv2875|M.tuberculosis_H37Rv         NSLKVGN-ADVVCGGVSTANATVYMIDSVLMP------------------
Mflv_4084|M.gilvum_PYR-GCK          NDLMVND-AGLVCGGVKTANATVYMIDTVLMP------------------
Mvan_2258|M.vanbaalenii_PYR-1       NDLKVND-ASVVCGGVQTANATVYLIDTVLMP------------------
MMAR_1834|M.marinum_M               NDLQVGD-AAVVCGGVQTANAVVYMIDTVLMP------------------
MSMEG_5196|M.smegmatis_MC2_155      GDIEVNDTAKLVCGAIHAQNARIYLIDTVLDPNNPPEALTPTVSGTSTTP
TH_1983|M.thermoresistible__bu      GDITVNDTAEVVCGGIQAANARIYLIDKVLDPAQAPDPITP---GSSSTN
                                    ..: *.: * :***.: : ** :*:**.** *                  

Mb2900|M.bovis_AF2122/97            ------------------------PA------
Rv2875|M.tuberculosis_H37Rv         ------------------------PA------
Mflv_4084|M.gilvum_PYR-GCK          ------------------------PAN-----
Mvan_2258|M.vanbaalenii_PYR-1       ------------------------PAA-----
MMAR_1834|M.marinum_M               ------------------------PS------
MSMEG_5196|M.smegmatis_MC2_155      TTTTETTEPAPAEAPESAETPEAMPAADAPIG
TH_1983|M.thermoresistible__bu      SSSDSSDSSGSSDSSE-----QALPAEDPTA-
                                                            *: