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YLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGEQGAKTLRGGKMEDVIFAGTSS RAPLGRAEVTVSIDNSDNALPIEYTEVSITRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIV GQGKLEEILQSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRRQLKPLGRQAEA AQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAAMRREHDEAAARLAVASEELAAHESAVAELST RAESIQHTWFGLSALAERVDATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAELD AARARLDAARAELADRERRAAEADRAHLAAVREEADRREGLARLAGQVETMRARVESIDESVARLSERIE DAAMRAQQTRAEFETVQGRIGELDQGEVGLDEHHERTVAALRLADERVAELQSAERAAERQVASLRARID ALAVGLQRKDGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLTAAGSAVSALKQ ADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVESPPQLVGAMIAMLSGVAVVNDLTEAMGLVEI RPELRAVTVDGDLVGAGWVSGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSARQDA AEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAVRTQTLDDVIQLETQLRKAQET QRVQVAQPIDRQAISAAADRARGVEVEARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAAR LHAAAVAAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTLSARVGELTDSLHRD ELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPHVALPPTELEMAEFEQARERGEQVIAPAPMPFDRV TQERRAKRAERALAELGRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVFNDAF VDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKITRLSLLSGGEKALTAVAMLVAIFR ARPSPFYIMDEVEAALDDVNLRRLLSLFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQR MRGQQVDQLVTNSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2922c | smc | - | 100% (1205) | PROBABLE CHROMOSOME PARTITION PROTEIN SMC |
| M. tuberculosis H37Rv | Rv1696 | recN | 2e-10 | 24.57% (468) | DNA repair protein recN (recombination protein N) |
| M. tuberculosis H37Rv | Rv1278 | - | 2e-08 | 23.45% (759) | hypothetical protein Rv1278 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2946c | smc | 0.0 | 99.83% (1205) | chromosome partition protein Smc |
| M. gilvum PYR-GCK | Mflv_4188 | - | 0.0 | 75.93% (1205) | chromosome segregation protein SMC |
| M. leprae Br4923 | MLBr_01629 | smc | 0.0 | 79.22% (1208) | putative cell division protein |
| M. abscessus ATCC 19977 | MAB_3246c | - | 0.0 | 69.24% (1164) | chromosome partition protein Smc |
| M. marinum M | MMAR_1785 | smc | 0.0 | 84.15% (1205) | chromosome partition protein Smc |
| M. avium 104 | MAV_3777 | smc | 0.0 | 83.96% (1203) | chromosome segregation protein SMC |
| M. smegmatis MC2 155 | MSMEG_2423 | smc | 0.0 | 74.79% (1206) | chromosome segregation protein SMC |
| M. thermoresistible (build 8) | TH_1649 | smc | 1e-125 | 84.79% (263) | PROBABLE CHROMOSOME PARTITION PROTEIN SMC |
| M. ulcerans Agy99 | MUL_2033 | smc | 0.0 | 83.73% (1205) | chromosome partition protein Smc |
| M. vanbaalenii PYR-1 | Mvan_2175 | - | 0.0 | 75.86% (1197) | chromosome segregation protein SMC |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4188|M.gilvum_PYR-GCK MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
Mvan_2175|M.vanbaalenii_PYR-1 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
MSMEG_2423|M.smegmatis_MC2_155 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
Mb2946c|M.bovis_AF2122/97 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MMAR_1785|M.marinum_M MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MUL_2033|M.ulcerans_Agy99 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MAV_3777|M.avium_104 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MLBr_01629|M.leprae_Br4923 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MAB_3246c|M.abscessus_ATCC_199 ----------------------------------------MDALTWVMGE
Mflv_4188|M.gilvum_PYR-GCK QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
Mvan_2175|M.vanbaalenii_PYR-1 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
MSMEG_2423|M.smegmatis_MC2_155 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI
Mb2946c|M.bovis_AF2122/97 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI
MMAR_1785|M.marinum_M QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYTEVSI
MUL_2033|M.ulcerans_Agy99 QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALPIEYTEVSI
MAV_3777|M.avium_104 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYSEVSI
MLBr_01629|M.leprae_Br4923 QGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSI
MAB_3246c|M.abscessus_ATCC_199 QGAKALRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDHALPIEYSEVSI
Mflv_4188|M.gilvum_PYR-GCK TRRMFRDGAGEYEINGSRCRLADVQELLSDSGIGREMHVIVGQGKLSEIL
Mvan_2175|M.vanbaalenii_PYR-1 TRRMFRDGAGEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL
MSMEG_2423|M.smegmatis_MC2_155 TRRMFRDGAGEYEINGASCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL
Mb2946c|M.bovis_AF2122/97 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL
MMAR_1785|M.marinum_M TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MUL_2033|M.ulcerans_Agy99 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MAV_3777|M.avium_104 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MLBr_01629|M.leprae_Br4923 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDQIL
MAB_3246c|M.abscessus_ATCC_199 TRRMFRDGAGEYEINGQTCRLMDVQELLSDSGIGREMHVIVGQGRLSQIL
Mflv_4188|M.gilvum_PYR-GCK ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR
Mvan_2175|M.vanbaalenii_PYR-1 ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMSANLARLTDLTTELRR
MSMEG_2423|M.smegmatis_MC2_155 ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR
Mb2946c|M.bovis_AF2122/97 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR
MMAR_1785|M.marinum_M QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MUL_2033|M.ulcerans_Agy99 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MAV_3777|M.avium_104 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MLBr_01629|M.leprae_Br4923 QSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTELRR
MAB_3246c|M.abscessus_ATCC_199 ESRPEDRRAFVEEAAGVLKHRKRKEKAVRKLESMAANLARLTDLTTELRR
Mflv_4188|M.gilvum_PYR-GCK QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVARKAEFDDTDQAETT
Mvan_2175|M.vanbaalenii_PYR-1 QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVTRKAEFDDTNQAETT
MSMEG_2423|M.smegmatis_MC2_155 QLKPLGRQAEMARRAATIQADLRDARLRLAADDLVRRQVEFQNTNQAETA
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA
Mb2946c|M.bovis_AF2122/97 QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA
MMAR_1785|M.marinum_M QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT
MUL_2033|M.ulcerans_Agy99 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT
MAV_3777|M.avium_104 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDLVNRRGEREAIFEAEAA
MLBr_01629|M.leprae_Br4923 QLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEAETM
MAB_3246c|M.abscessus_ATCC_199 QLKPLGRQAEVARRAATVQADLRDARLRLAADDLVSRRADFDGTNDAETA
Mflv_4188|M.gilvum_PYR-GCK LRREHDELTERLQERAAELDAHETAVEDLSERADAAQQRWFRLSALAERV
Mvan_2175|M.vanbaalenii_PYR-1 LRREHDELTERMEARTLELDAHESAVADLSERADAAQQRWFRLSALAERV
MSMEG_2423|M.smegmatis_MC2_155 LRKEHEELTVRLQSATVELQAHEAAVAELTRRAEAAQQTWFRASALAERV
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV
Mb2946c|M.bovis_AF2122/97 MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV
MMAR_1785|M.marinum_M MRREHDEAAARLTVAAEELAAHEAALAELTSRAESVQHTWFGLSALAERV
MUL_2033|M.ulcerans_Agy99 MRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFGLSALAERV
MAV_3777|M.avium_104 MRREHDEASARLAVASEELAAHEKALGELSGRAESVQQTWFALSALAERV
MLBr_01629|M.leprae_Br4923 MRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLVERV
MAB_3246c|M.abscessus_ATCC_199 LRKEHAEITDRLEVATALLAEHETALGELLPQAELAQQTWFRLSALAERV
Mflv_4188|M.gilvum_PYR-GCK SATVRIASERAQHLDGDPDFSAGPDP---DELEAQADAVAEQEQQLLDEL
Mvan_2175|M.vanbaalenii_PYR-1 SATVRIASERAQHLDAEPDFSAGPDP---DELEAQADAVAEQEQLLLDEL
MSMEG_2423|M.smegmatis_MC2_155 GATVRIATDRAQMLDSEPEMSSGRDP---DALEAEAEEVAELEAQLLDEL
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL
Mb2946c|M.bovis_AF2122/97 DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL
MMAR_1785|M.marinum_M GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL
MUL_2033|M.ulcerans_Agy99 GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL
MAV_3777|M.avium_104 AATVRIASERAQHLDLGPVTAGDTDP---DALDAEAERVAAAEQQLLAEL
MLBr_01629|M.leprae_Br4923 SATIRIAGERAYHLDVDPATPSDTDP---DVLEAEAQQMEVAEQQLLAEL
MAB_3246c|M.abscessus_ATCC_199 SATVRIAGERASHLDEVAAAPTGPDP---EELEAQAERVAEQERLLIAQL
Mflv_4188|M.gilvum_PYR-GCK AESQERLEAAREELAEREQAAAEAERAHMAAARAEADRREGLARLSGQVD
Mvan_2175|M.vanbaalenii_PYR-1 AESQARLESARAELGEREQAAAEAERAHMAAARAEADRREGLARLSGQVD
MSMEG_2423|M.smegmatis_MC2_155 SEARIALETARAELAEREQIAADAERAHMAAARAEADRREGLARLAGQVD
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv DAARARLDAARAELADRERRAAEADRAHLAAVREEADRREGLARLAGQVE
Mb2946c|M.bovis_AF2122/97 DAARARLDAARAERADRERRAAEADRAHLAAVREEADRREGLARLAGQVE
MMAR_1785|M.marinum_M AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE
MUL_2033|M.ulcerans_Agy99 AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE
MAV_3777|M.avium_104 AAARSRLETARAELAEREREAAEADRAHMAAVRAEADRREGLARLAGQVE
MLBr_01629|M.leprae_Br4923 AVARTQLEAARAELADRERHAVEADKAHLEAVRAEADRREGLALLAGQVE
MAB_3246c|M.abscessus_ATCC_199 ETVTEQLATAKAELSARESAVAQAQRQHMAAVAAEADRREGLARLTGQVD
Mflv_4188|M.gilvum_PYR-GCK TMRTRVESVDETVARLTANIDDAAARAQLTQAEFETVQARVGELDAGEVG
Mvan_2175|M.vanbaalenii_PYR-1 TMRTRVDSVDETVARLTASIDEAGARAQQTQAEFETVQGRVAELDSGEVG
MSMEG_2423|M.smegmatis_MC2_155 TMRTRVESIDEGVLRLSVSIEEAAAKAEHAQAEFEDVQSRVGELDAGEVG
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG
Mb2946c|M.bovis_AF2122/97 TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG
MMAR_1785|M.marinum_M TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG
MUL_2033|M.ulcerans_Agy99 TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG
MAV_3777|M.avium_104 TMRARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELDQGEVG
MLBr_01629|M.leprae_Br4923 TMRARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEVH
MAB_3246c|M.abscessus_ATCC_199 TMRTRLESIDGQAQRLTESIVEATVRGEAAQTEFDTVKARVAELDQGEVG
Mflv_4188|M.gilvum_PYR-GCK LDEHHDRSVAALRLADERVAELLAAERAAERQVASLQARIDALSVGLDRR
Mvan_2175|M.vanbaalenii_PYR-1 LDEHHDRTVAALRLADERVTELQAAERAAERRVASLQARIDALSVGLDRK
MSMEG_2423|M.smegmatis_MC2_155 LDEHHDRTVAALRLADERVAELQAAERAAERQVASLRARIEALSVGLDRR
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK
Mb2946c|M.bovis_AF2122/97 LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK
MMAR_1785|M.marinum_M LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIEALSVGLDRK
MUL_2033|M.ulcerans_Agy99 LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSVGLDRK
MAV_3777|M.avium_104 LDEHHERTVAALRLADERVAELQAAERDAERKVASLRARIDALAVGLERK
MLBr_01629|M.leprae_Br4923 LDEQHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLERK
MAB_3246c|M.abscessus_ATCC_199 LDEHHERSISSLSIANERVAELQSAERQAERQIASLKARIDALAIGLERK
Mflv_4188|M.gilvum_PYR-GCK DGAAWLQENHSGAGLFGSIANLVKVRAGHEAAIAAMLGAAADALAAEDFG
Mvan_2175|M.vanbaalenii_PYR-1 DGAAWLKENRSGAGLFDSLANLVKVRPGHEAAIAAVLGAAADALAAENSG
MSMEG_2423|M.smegmatis_MC2_155 DGAAWLQKNHSGGGLFGSIGDFLRVQPGYEVAVAAVLGAAADALAAENFG
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT
Mb2946c|M.bovis_AF2122/97 DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT
MMAR_1785|M.marinum_M DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG
MUL_2033|M.ulcerans_Agy99 DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG
MAV_3777|M.avium_104 DGTAWLTENHSGAGILGPMAKLVKVRSGYEAAVAAVLGSAADALAADGLG
MLBr_01629|M.leprae_Br4923 DGAAWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSLG
MAB_3246c|M.abscessus_ATCC_199 DGSAWLAENRSGAGIFGSIAQLVKVRPGYQGAIATAMGPAADAVAAENPA
Mflv_4188|M.gilvum_PYR-GCK AARAAVAALKESDGGRAALVLGDWP---AQEAVTG-QLPAGAAWAVDLVE
Mvan_2175|M.vanbaalenii_PYR-1 AARDALAALKESDGGRAAIVLGDWP---ARTPATG-QLPAGAAWAVDLVD
MSMEG_2423|M.smegmatis_MC2_155 AAAAAVAALKESDGGRAAIVLGDWN---AIGSSPQAALPPGATWATDLVS
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE
Mb2946c|M.bovis_AF2122/97 AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE
MMAR_1785|M.marinum_M AARSAVTALKQADGGRAALVLGDWPDANDHRAAG--GLPSGTLWALDLIE
MUL_2033|M.ulcerans_Agy99 AARSAVTALKQADGGRAALVLGDWPDAHDHRAAG--GLPSGTLWALDLIE
MAV_3777|M.avium_104 AARSALGALKQADGGRAALVLGDWP--ADPPAPQ--PAPAGALWALDLID
MLBr_01629|M.leprae_Br4923 AARSALTALKEADAGRATLVLADWLADAGPACVT--GLPDGAQRALDLIE
MAB_3246c|M.abscessus_ATCC_199 AAHEAVKALKSSDGGRAAIVFGDWPAHTGARPAVT--LPPGAHWANDLVE
Mflv_4188|M.gilvum_PYR-GCK PADRVRGAVTAMLSGVAVVENLTAALDLVAAQPRLRAVTADGDLVGAGWV
Mvan_2175|M.vanbaalenii_PYR-1 PAPRIQGAVTAMLGGVAVVGDLTAALELVAAQPELRAVTADGDLVGAGWV
MSMEG_2423|M.smegmatis_MC2_155 VPDRLRGAVTAMLTGVAVVPDMAAGLALVSSRPELRAVTTEGDLVGPGWV
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV
Mb2946c|M.bovis_AF2122/97 SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV
MMAR_1785|M.marinum_M VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV
MUL_2033|M.ulcerans_Agy99 VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV
MAV_3777|M.avium_104 APERLRGAITAMLSGVAVVDDLDRALALVAEHPRLRAVTLDGDLVGAGWV
MLBr_01629|M.leprae_Br4923 APPWLQGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWV
MAB_3246c|M.abscessus_ATCC_199 APQRLAAAVSAMLASVVVVDELGAAIDVVLANPLLRAVTIDGDRVGAGWV
Mflv_4188|M.gilvum_PYR-GCK SGGSDRKPSTLEIQSEVDRARSELVDAERRTGELSAALSGALAEQAARQD
Mvan_2175|M.vanbaalenii_PYR-1 SGGSDRKPSTLEITSEVDKARAELVDAERQTGELSAALSGALAEQAARQD
MSMEG_2423|M.smegmatis_MC2_155 SGGSDRKPSTLEIASEIDKARAELEQAERQTSELGAALSGALAEQSARQD
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSARQD
Mb2946c|M.bovis_AF2122/97 SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSAGQD
MMAR_1785|M.marinum_M SGGSDRKPSTLEITSEIDKARSELAAAEVRVAELGAALSGALTDQTARQD
MUL_2033|M.ulcerans_Agy99 SGGSDRKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTARQD
MAV_3777|M.avium_104 SGGSDRKLSTLEVTSEIDKASAELAAAEAQVAQLSAALSGALAEQAARQD
MLBr_01629|M.leprae_Br4923 SGGSGRRLSTLEVTSEIDKAGAELAAAEAHMAQLNAALSGALSEQVAHSD
MAB_3246c|M.abscessus_ATCC_199 AGGSDKKQSTLEVQAAIEAAREELRATETQVGEISAALAGALAEQTARQD
Mflv_4188|M.gilvum_PYR-GCK AAEHALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIRQRDEMEAG
Mvan_2175|M.vanbaalenii_PYR-1 AAEQALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIKQRDELEAG
MSMEG_2423|M.smegmatis_MC2_155 AAEQALAALNESDAAISAIYEQLARLGQEARGAHQEWQRLIKQRDELEAG
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV
Mb2946c|M.bovis_AF2122/97 AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV
MMAR_1785|M.marinum_M AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG
MUL_2033|M.ulcerans_Agy99 AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG
MAV_3777|M.avium_104 SAEQALAALNESDSAISGMYEQLGRLGQEARTSEDEWSRLLRQREELEAG
MLBr_01629|M.leprae_Br4923 ATEQALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEAR
MAB_3246c|M.abscessus_ATCC_199 TAEQALAALNESDAAISAVYEQLGRVGQEVRAAAEEVKKLTLQRDQLERG
Mflv_4188|M.gilvum_PYR-GCK RNRTVSELAELELRLQNAQREP-MFDAEV---VDRTEFTAAAEAARSAEV
Mvan_2175|M.vanbaalenii_PYR-1 RNRTVEELAELESRLHNAQQEP-MFDVEV---VDRTEFTAAAEAARSAEV
MSMEG_2423|M.smegmatis_MC2_155 RTKTVEELRELESRLSNAEQTP-MFDIEP---VDRQETVAAAEAARAVEV
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV
Mb2946c|M.bovis_AF2122/97 RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV
MMAR_1785|M.marinum_M RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV
MUL_2033|M.ulcerans_Agy99 RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV
MAV_3777|M.avium_104 RTQTVAEVTELENRLRNAQETPQEPAAEP---VNRQQIAAATDAARSAEV
MLBr_01629|M.leprae_Br4923 RVSILEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEV
MAB_3246c|M.abscessus_ATCC_199 RATTLEELAEVESRLRNAEEAPNLFDDEP---LDRDDMAIELEEARSVEI
Mflv_4188|M.gilvum_PYR-GCK EARLSVRTAEERANAVRGRADSLRRAAVAEREARVRAQRAREARVHAAAV
Mvan_2175|M.vanbaalenii_PYR-1 EARLAVRTAEERANAVRGRADSLRRAAVAEREARARAQRAREARVQAAAV
MSMEG_2423|M.smegmatis_MC2_155 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQRAREAREYAARV
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV
Mb2946c|M.bovis_AF2122/97 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV
MMAR_1785|M.marinum_M EARLTVRTAEERANALRGRADSLRRAAAAEREARVRAELARAVRLRSAAV
MUL_2033|M.ulcerans_Agy99 EARLTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAAV
MAV_3777|M.avium_104 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQAREARLRAAAV
MLBr_01629|M.leprae_Br4923 EALLAVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAV
MAB_3246c|M.abscessus_ATCC_199 EARLAVRTSEERVNSVRGKADSLRRAAVAEREARARAARAAAARMRAAAV
Mflv_4188|M.gilvum_PYR-GCK AAAVAESGRAVAQRLADAVSVASRIRDEVAAERQVRAGALTKAREEVNEL
Mvan_2175|M.vanbaalenii_PYR-1 AAAVAESGRLVAQRLADAVAVASRIRDEVAAERHVRAAALTKAREEVAEL
MSMEG_2423|M.smegmatis_MC2_155 AAAVSECGRQIAGKLSAVVAAAARSRDELATERQLRVNALGEIREEVTAL
TH_1649|M.thermoresistible__bu --------------------------------------------------
Rv2922c|M.tuberculosis_H37Rv AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL
Mb2946c|M.bovis_AF2122/97 AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL
MMAR_1785|M.marinum_M AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL
MUL_2033|M.ulcerans_Agy99 AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL
MAV_3777|M.avium_104 AAAVADSGRLLATRLNAVVAAASRIRDALAAERQQRATAMTAVRDEVNAL
MLBr_01629|M.leprae_Br4923 AAAVTDCGQLLASRLTQAVDLAARHRDALATERQQRSVAIAAVRYEVNTL
MAB_3246c|M.abscessus_ATCC_199 AAAVAESGRMVAARLEHVVAAASARRDELSATRAQHTSAIGAVRDQVREL
Mflv_4188|M.gilvum_PYR-GCK TARITALTDALHRDEVAKAQAALRIEQLEQQVLEQFGMAVADLVAEYGPD
Mvan_2175|M.vanbaalenii_PYR-1 TARIAALTDSLHRDEVAKAQAALRIEQLEQQVLEQFGIAVADLIAEYGPD
MSMEG_2423|M.smegmatis_MC2_155 NNRINTLTDALHRDEMAKAQAQLRIEQLEAQVLEQFGMSAGDLVAEYGPQ
TH_1649|M.thermoresistible__bu -------------------------------------MSADDLIAEYGPH
Rv2922c|M.tuberculosis_H37Rv SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH
Mb2946c|M.bovis_AF2122/97 SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH
MMAR_1785|M.marinum_M SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD
MUL_2033|M.ulcerans_Agy99 SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD
MAV_3777|M.avium_104 SARVAALTDSLHRDEVANAQAALRIEQLEQMVLEQFGMAPADLIAEYGPH
MLBr_01629|M.leprae_Br4923 RVRLATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDLIAEYGPQ
MAB_3246c|M.abscessus_ATCC_199 TQAQTRLTDALHRDEVAKAQAALRIEQLSEQVLEQFGMAADDLIAEYGPH
:: **::****.
Mflv_4188|M.gilvum_PYR-GCK VALPPSELEMAEYEQARERGEQVTAPAPMPYDRPTQERRAKRAERELKEL
Mvan_2175|M.vanbaalenii_PYR-1 VPLPPSELEMAEYEQAKERGEQVTAPAPMPYDRPTQERRAKRADKELREL
MSMEG_2423|M.smegmatis_MC2_155 VALPPSELEMAEYEQAKERGEQVTAPAPMPFDRATQERRAKRAERELAEL
TH_1649|M.thermoresistible__bu VPLPPTELEMAEYEQALERGEQVTKPAPMPYDRATQERRAKRAERELAEL
Rv2922c|M.tuberculosis_H37Rv VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL
Mb2946c|M.bovis_AF2122/97 VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL
MMAR_1785|M.marinum_M VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL
MUL_2033|M.ulcerans_Agy99 VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL
MAV_3777|M.avium_104 IALPPSELEMAEYEQAKERGEQVFAPAPIPFDRPTQERRAKRAERELAEL
MLBr_01629|M.leprae_Br4923 VALLPTELEMAEFQQARERGEQVTSPAPMPYDRATQERRAKRAERELAEL
MAB_3246c|M.abscessus_ATCC_199 IELPPSQQEIDEYEQARERGEQVSAPLPMPFDRDTQERRAKRAEKDLREL
: * *:: *: *::** ****** * *:*:** **:******:: * **
Mflv_4188|M.gilvum_PYR-GCK GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIAEVDTRILQVF
Mvan_2175|M.vanbaalenii_PYR-1 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDSRILQVF
MSMEG_2423|M.smegmatis_MC2_155 GRVNPLALEEFAALEERYNFLSTQLEDVKAARADLLDVIADVDNRILQVF
TH_1649|M.thermoresistible__bu GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDQRILQLF
Rv2922c|M.tuberculosis_H37Rv GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF
Mb2946c|M.bovis_AF2122/97 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF
MMAR_1785|M.marinum_M GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF
MUL_2033|M.ulcerans_Agy99 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF
MAV_3777|M.avium_104 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVDEVDARILQVF
MLBr_01629|M.leprae_Br4923 GRVNPLALEEFAALEERYNFLSTQLEDVKGARKDLLDVVAEVDARILQVF
MAB_3246c|M.abscessus_ATCC_199 GKVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDERILQVF
*:***************************.** ***.*: :** ****:*
Mflv_4188|M.gilvum_PYR-GCK TEAYMDVEREFTQVFSTLFPGGEGRLLLTNPSDMLTTGIEVEARPPGKKI
Mvan_2175|M.vanbaalenii_PYR-1 TEAYMDVEREFTQVFSTLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI
MSMEG_2423|M.smegmatis_MC2_155 TEAYADVEREFEQVFATLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI
TH_1649|M.thermoresistible__bu AEAYTDVEREFREVFATLFPGGEGRLLLTDPNDMLTTGVEVEARPPGKKI
Rv2922c|M.tuberculosis_H37Rv NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI
Mb2946c|M.bovis_AF2122/97 NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI
MMAR_1785|M.marinum_M SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV
MUL_2033|M.ulcerans_Agy99 SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV
MAV_3777|M.avium_104 SEAYTDVEREFSDVFGVLFPGGEGRLRLTDPSNMLTTGIEVEARPPGKKI
MLBr_01629|M.leprae_Br4923 SDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIEVEARPSGKKV
MAB_3246c|M.abscessus_ATCC_199 TEAYADVEREFKGVFSSLFPGGEGRLVLTDPNDMLTTGIEVEARPPGKKV
:*: ****** ** ********* ** *.:*****:******.***:
Mflv_4188|M.gilvum_PYR-GCK KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
Mvan_2175|M.vanbaalenii_PYR-1 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
MSMEG_2423|M.smegmatis_MC2_155 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
TH_1649|M.thermoresistible__bu KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
Rv2922c|M.tuberculosis_H37Rv TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS
Mb2946c|M.bovis_AF2122/97 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS
MMAR_1785|M.marinum_M SRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIG
MUL_2033|M.ulcerans_Agy99 SRLSLLSGGEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIG
MAV_3777|M.avium_104 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIS
MLBr_01629|M.leprae_Br4923 SRLSLLSGGEKSLIAVAMLVAIFKARPSPFYIMDEVEAALDDVNLCRLIG
MAB_3246c|M.abscessus_ATCC_199 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLQRLIG
.**********:* ***:*****:*******:**********.** **:.
Mflv_4188|M.gilvum_PYR-GCK LFEQLRERSQLIVITHQKPTMEVADALYGVTMQGDGITTVISQRMRGQ--
Mvan_2175|M.vanbaalenii_PYR-1 LFEQLRERSQLIVITHQKPTMEVADALYGVTMRGDGITTVISQRMRGQ--
MSMEG_2423|M.smegmatis_MC2_155 LFEQLREKSQLIVITHQKPTMEIADALYGVTMRGDGITTVISQRMRGQ--
TH_1649|M.thermoresistible__bu LFEQLRERSQLIVITHQKPTMEVADALYGVTMRDDGITTVISQRLRGQ--
Rv2922c|M.tuberculosis_H37Rv LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV
Mb2946c|M.bovis_AF2122/97 LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV
MMAR_1785|M.marinum_M LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV
MUL_2033|M.ulcerans_Agy99 LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV
MAV_3777|M.avium_104 LFELLRARSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRMRGQQV
MLBr_01629|M.leprae_Br4923 VFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAVISQRMRGQQV
MAB_3246c|M.abscessus_ATCC_199 LFEQLREKSQLIVITHQKPTMEVADALYGVSMRDDGITQVVSQRMRGLET
:** ** :**:*:*********:**:****:*:.**** *:***:**
Mflv_4188|M.gilvum_PYR-GCK -ELVTSSS
Mvan_2175|M.vanbaalenii_PYR-1 -ELVASPS
MSMEG_2423|M.smegmatis_MC2_155 -ELVSNPS
TH_1649|M.thermoresistible__bu -ELVAQPG
Rv2922c|M.tuberculosis_H37Rv DQLVTNSS
Mb2946c|M.bovis_AF2122/97 DQLVTNSS
MMAR_1785|M.marinum_M DRLVANSS
MUL_2033|M.ulcerans_Agy99 DRLVANSS
MAV_3777|M.avium_104 DQLVTT--
MLBr_01629|M.leprae_Br4923 ESLVTSSS
MAB_3246c|M.abscessus_ATCC_199 -QLASQNA
*.: