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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1649 | smc | - | 100% (269) | PROBABLE CHROMOSOME PARTITION PROTEIN SMC |
M. thermoresistible (build 8) | TH_0007 | - | 2e-05 | 23.90% (251) | conserved hypothetical protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2946c | smc | 1e-125 | 84.79% (263) | chromosome partition protein Smc |
M. gilvum PYR-GCK | Mflv_4188 | - | 1e-132 | 90.53% (264) | chromosome segregation protein SMC |
M. tuberculosis H37Rv | Rv2922c | smc | 1e-125 | 84.79% (263) | chromosome partition protein Smc |
M. leprae Br4923 | MLBr_01629 | smc | 1e-122 | 84.17% (259) | putative cell division protein |
M. abscessus ATCC 19977 | MAB_3246c | - | 1e-128 | 85.50% (262) | chromosome partition protein Smc |
M. marinum M | MMAR_1785 | smc | 1e-124 | 83.65% (263) | chromosome partition protein Smc |
M. avium 104 | MAV_3777 | smc | 1e-125 | 84.79% (263) | chromosome segregation protein SMC |
M. smegmatis MC2 155 | MSMEG_2423 | smc | 1e-136 | 91.39% (267) | chromosome segregation protein SMC |
M. ulcerans Agy99 | MUL_2033 | smc | 1e-124 | 83.27% (263) | chromosome partition protein Smc |
M. vanbaalenii PYR-1 | Mvan_2175 | - | 1e-135 | 92.40% (263) | chromosome segregation protein SMC |
CLUSTAL 2.0.9 multiple sequence alignment TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE Mflv_4188|M.gilvum_PYR-GCK MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE Mvan_2175|M.vanbaalenii_PYR-1 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE MMAR_1785|M.marinum_M MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE MUL_2033|M.ulcerans_Agy99 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE MAV_3777|M.avium_104 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE Mb2946c|M.bovis_AF2122/97 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE Rv2922c|M.tuberculosis_H37Rv MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE MLBr_01629|M.leprae_Br4923 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE MAB_3246c|M.abscessus_ATCC_199 ----------------------------------------MDALTWVMGE TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI Mflv_4188|M.gilvum_PYR-GCK QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI Mvan_2175|M.vanbaalenii_PYR-1 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI MMAR_1785|M.marinum_M QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYTEVSI MUL_2033|M.ulcerans_Agy99 QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALPIEYTEVSI MAV_3777|M.avium_104 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYSEVSI Mb2946c|M.bovis_AF2122/97 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI Rv2922c|M.tuberculosis_H37Rv QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI MLBr_01629|M.leprae_Br4923 QGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSI MAB_3246c|M.abscessus_ATCC_199 QGAKALRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDHALPIEYSEVSI TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 TRRMFRDGAGEYEINGASCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL Mflv_4188|M.gilvum_PYR-GCK TRRMFRDGAGEYEINGSRCRLADVQELLSDSGIGREMHVIVGQGKLSEIL Mvan_2175|M.vanbaalenii_PYR-1 TRRMFRDGAGEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL MMAR_1785|M.marinum_M TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL MUL_2033|M.ulcerans_Agy99 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL MAV_3777|M.avium_104 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL Mb2946c|M.bovis_AF2122/97 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL Rv2922c|M.tuberculosis_H37Rv TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL MLBr_01629|M.leprae_Br4923 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDQIL MAB_3246c|M.abscessus_ATCC_199 TRRMFRDGAGEYEINGQTCRLMDVQELLSDSGIGREMHVIVGQGRLSQIL TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR Mflv_4188|M.gilvum_PYR-GCK ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR Mvan_2175|M.vanbaalenii_PYR-1 ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMSANLARLTDLTTELRR MMAR_1785|M.marinum_M QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR MUL_2033|M.ulcerans_Agy99 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR MAV_3777|M.avium_104 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR Mb2946c|M.bovis_AF2122/97 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR Rv2922c|M.tuberculosis_H37Rv QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR MLBr_01629|M.leprae_Br4923 QSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTELRR MAB_3246c|M.abscessus_ATCC_199 ESRPEDRRAFVEEAAGVLKHRKRKEKAVRKLESMAANLARLTDLTTELRR TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 QLKPLGRQAEMARRAATIQADLRDARLRLAADDLVRRQVEFQNTNQAETA Mflv_4188|M.gilvum_PYR-GCK QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVARKAEFDDTDQAETT Mvan_2175|M.vanbaalenii_PYR-1 QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVTRKAEFDDTNQAETT MMAR_1785|M.marinum_M QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT MUL_2033|M.ulcerans_Agy99 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT MAV_3777|M.avium_104 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDLVNRRGEREAIFEAEAA Mb2946c|M.bovis_AF2122/97 QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA Rv2922c|M.tuberculosis_H37Rv QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA MLBr_01629|M.leprae_Br4923 QLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEAETM MAB_3246c|M.abscessus_ATCC_199 QLKPLGRQAEVARRAATVQADLRDARLRLAADDLVSRRADFDGTNDAETA TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 LRKEHEELTVRLQSATVELQAHEAAVAELTRRAEAAQQTWFRASALAERV Mflv_4188|M.gilvum_PYR-GCK LRREHDELTERLQERAAELDAHETAVEDLSERADAAQQRWFRLSALAERV Mvan_2175|M.vanbaalenii_PYR-1 LRREHDELTERMEARTLELDAHESAVADLSERADAAQQRWFRLSALAERV MMAR_1785|M.marinum_M MRREHDEAAARLTVAAEELAAHEAALAELTSRAESVQHTWFGLSALAERV MUL_2033|M.ulcerans_Agy99 MRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFGLSALAERV MAV_3777|M.avium_104 MRREHDEASARLAVASEELAAHEKALGELSGRAESVQQTWFALSALAERV Mb2946c|M.bovis_AF2122/97 MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV Rv2922c|M.tuberculosis_H37Rv MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV MLBr_01629|M.leprae_Br4923 MRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLVERV MAB_3246c|M.abscessus_ATCC_199 LRKEHAEITDRLEVATALLAEHETALGELLPQAELAQQTWFRLSALAERV TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 GATVRIATDRAQMLDSEPEMSSGRDP---DALEAEAEEVAELEAQLLDEL Mflv_4188|M.gilvum_PYR-GCK SATVRIASERAQHLDGDPDFSAGPDP---DELEAQADAVAEQEQQLLDEL Mvan_2175|M.vanbaalenii_PYR-1 SATVRIASERAQHLDAEPDFSAGPDP---DELEAQADAVAEQEQLLLDEL MMAR_1785|M.marinum_M GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL MUL_2033|M.ulcerans_Agy99 GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL MAV_3777|M.avium_104 AATVRIASERAQHLDLGPVTAGDTDP---DALDAEAERVAAAEQQLLAEL Mb2946c|M.bovis_AF2122/97 DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL Rv2922c|M.tuberculosis_H37Rv DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL MLBr_01629|M.leprae_Br4923 SATIRIAGERAYHLDVDPATPSDTDP---DVLEAEAQQMEVAEQQLLAEL MAB_3246c|M.abscessus_ATCC_199 SATVRIAGERASHLDEVAAAPTGPDP---EELEAQAERVAEQERLLIAQL TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 SEARIALETARAELAEREQIAADAERAHMAAARAEADRREGLARLAGQVD Mflv_4188|M.gilvum_PYR-GCK AESQERLEAAREELAEREQAAAEAERAHMAAARAEADRREGLARLSGQVD Mvan_2175|M.vanbaalenii_PYR-1 AESQARLESARAELGEREQAAAEAERAHMAAARAEADRREGLARLSGQVD MMAR_1785|M.marinum_M AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE MUL_2033|M.ulcerans_Agy99 AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE MAV_3777|M.avium_104 AAARSRLETARAELAEREREAAEADRAHMAAVRAEADRREGLARLAGQVE Mb2946c|M.bovis_AF2122/97 DAARARLDAARAERADRERRAAEADRAHLAAVREEADRREGLARLAGQVE Rv2922c|M.tuberculosis_H37Rv DAARARLDAARAELADRERRAAEADRAHLAAVREEADRREGLARLAGQVE MLBr_01629|M.leprae_Br4923 AVARTQLEAARAELADRERHAVEADKAHLEAVRAEADRREGLALLAGQVE MAB_3246c|M.abscessus_ATCC_199 ETVTEQLATAKAELSARESAVAQAQRQHMAAVAAEADRREGLARLTGQVD TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 TMRTRVESIDEGVLRLSVSIEEAAAKAEHAQAEFEDVQSRVGELDAGEVG Mflv_4188|M.gilvum_PYR-GCK TMRTRVESVDETVARLTANIDDAAARAQLTQAEFETVQARVGELDAGEVG Mvan_2175|M.vanbaalenii_PYR-1 TMRTRVDSVDETVARLTASIDEAGARAQQTQAEFETVQGRVAELDSGEVG MMAR_1785|M.marinum_M TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG MUL_2033|M.ulcerans_Agy99 TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG MAV_3777|M.avium_104 TMRARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELDQGEVG Mb2946c|M.bovis_AF2122/97 TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG Rv2922c|M.tuberculosis_H37Rv TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG MLBr_01629|M.leprae_Br4923 TMRARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEVH MAB_3246c|M.abscessus_ATCC_199 TMRTRLESIDGQAQRLTESIVEATVRGEAAQTEFDTVKARVAELDQGEVG TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 LDEHHDRTVAALRLADERVAELQAAERAAERQVASLRARIEALSVGLDRR Mflv_4188|M.gilvum_PYR-GCK LDEHHDRSVAALRLADERVAELLAAERAAERQVASLQARIDALSVGLDRR Mvan_2175|M.vanbaalenii_PYR-1 LDEHHDRTVAALRLADERVTELQAAERAAERRVASLQARIDALSVGLDRK MMAR_1785|M.marinum_M LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIEALSVGLDRK MUL_2033|M.ulcerans_Agy99 LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSVGLDRK MAV_3777|M.avium_104 LDEHHERTVAALRLADERVAELQAAERDAERKVASLRARIDALAVGLERK Mb2946c|M.bovis_AF2122/97 LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK Rv2922c|M.tuberculosis_H37Rv LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK MLBr_01629|M.leprae_Br4923 LDEQHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLERK MAB_3246c|M.abscessus_ATCC_199 LDEHHERSISSLSIANERVAELQSAERQAERQIASLKARIDALAIGLERK TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 DGAAWLQKNHSGGGLFGSIGDFLRVQPGYEVAVAAVLGAAADALAAENFG Mflv_4188|M.gilvum_PYR-GCK DGAAWLQENHSGAGLFGSIANLVKVRAGHEAAIAAMLGAAADALAAEDFG Mvan_2175|M.vanbaalenii_PYR-1 DGAAWLKENRSGAGLFDSLANLVKVRPGHEAAIAAVLGAAADALAAENSG MMAR_1785|M.marinum_M DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG MUL_2033|M.ulcerans_Agy99 DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG MAV_3777|M.avium_104 DGTAWLTENHSGAGILGPMAKLVKVRSGYEAAVAAVLGSAADALAADGLG Mb2946c|M.bovis_AF2122/97 DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT Rv2922c|M.tuberculosis_H37Rv DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT MLBr_01629|M.leprae_Br4923 DGAAWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSLG MAB_3246c|M.abscessus_ATCC_199 DGSAWLAENRSGAGIFGSIAQLVKVRPGYQGAIATAMGPAADAVAAENPA TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 AAAAAVAALKESDGGRAAIVLGDWN---AIGSSPQAALPPGATWATDLVS Mflv_4188|M.gilvum_PYR-GCK AARAAVAALKESDGGRAALVLGDWP---AQEAVTG-QLPAGAAWAVDLVE Mvan_2175|M.vanbaalenii_PYR-1 AARDALAALKESDGGRAAIVLGDWP---ARTPATG-QLPAGAAWAVDLVD MMAR_1785|M.marinum_M AARSAVTALKQADGGRAALVLGDWPDANDHRAAG--GLPSGTLWALDLIE MUL_2033|M.ulcerans_Agy99 AARSAVTALKQADGGRAALVLGDWPDAHDHRAAG--GLPSGTLWALDLIE MAV_3777|M.avium_104 AARSALGALKQADGGRAALVLGDWP--ADPPAPQ--PAPAGALWALDLID Mb2946c|M.bovis_AF2122/97 AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE Rv2922c|M.tuberculosis_H37Rv AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE MLBr_01629|M.leprae_Br4923 AARSALTALKEADAGRATLVLADWLADAGPACVT--GLPDGAQRALDLIE MAB_3246c|M.abscessus_ATCC_199 AAHEAVKALKSSDGGRAAIVFGDWPAHTGARPAVT--LPPGAHWANDLVE TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 VPDRLRGAVTAMLTGVAVVPDMAAGLALVSSRPELRAVTTEGDLVGPGWV Mflv_4188|M.gilvum_PYR-GCK PADRVRGAVTAMLSGVAVVENLTAALDLVAAQPRLRAVTADGDLVGAGWV Mvan_2175|M.vanbaalenii_PYR-1 PAPRIQGAVTAMLGGVAVVGDLTAALELVAAQPELRAVTADGDLVGAGWV MMAR_1785|M.marinum_M VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV MUL_2033|M.ulcerans_Agy99 VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV MAV_3777|M.avium_104 APERLRGAITAMLSGVAVVDDLDRALALVAEHPRLRAVTLDGDLVGAGWV Mb2946c|M.bovis_AF2122/97 SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV Rv2922c|M.tuberculosis_H37Rv SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV MLBr_01629|M.leprae_Br4923 APPWLQGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWV MAB_3246c|M.abscessus_ATCC_199 APQRLAAAVSAMLASVVVVDELGAAIDVVLANPLLRAVTIDGDRVGAGWV TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 SGGSDRKPSTLEIASEIDKARAELEQAERQTSELGAALSGALAEQSARQD Mflv_4188|M.gilvum_PYR-GCK SGGSDRKPSTLEIQSEVDRARSELVDAERRTGELSAALSGALAEQAARQD Mvan_2175|M.vanbaalenii_PYR-1 SGGSDRKPSTLEITSEVDKARAELVDAERQTGELSAALSGALAEQAARQD MMAR_1785|M.marinum_M SGGSDRKPSTLEITSEIDKARSELAAAEVRVAELGAALSGALTDQTARQD MUL_2033|M.ulcerans_Agy99 SGGSDRKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTARQD MAV_3777|M.avium_104 SGGSDRKLSTLEVTSEIDKASAELAAAEAQVAQLSAALSGALAEQAARQD Mb2946c|M.bovis_AF2122/97 SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSAGQD Rv2922c|M.tuberculosis_H37Rv SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSARQD MLBr_01629|M.leprae_Br4923 SGGSGRRLSTLEVTSEIDKAGAELAAAEAHMAQLNAALSGALSEQVAHSD MAB_3246c|M.abscessus_ATCC_199 AGGSDKKQSTLEVQAAIEAAREELRATETQVGEISAALAGALAEQTARQD TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 AAEQALAALNESDAAISAIYEQLARLGQEARGAHQEWQRLIKQRDELEAG Mflv_4188|M.gilvum_PYR-GCK AAEHALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIRQRDEMEAG Mvan_2175|M.vanbaalenii_PYR-1 AAEQALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIKQRDELEAG MMAR_1785|M.marinum_M AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG MUL_2033|M.ulcerans_Agy99 AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG MAV_3777|M.avium_104 SAEQALAALNESDSAISGMYEQLGRLGQEARTSEDEWSRLLRQREELEAG Mb2946c|M.bovis_AF2122/97 AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV Rv2922c|M.tuberculosis_H37Rv AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV MLBr_01629|M.leprae_Br4923 ATEQALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEAR MAB_3246c|M.abscessus_ATCC_199 TAEQALAALNESDAAISAVYEQLGRVGQEVRAAAEEVKKLTLQRDQLERG TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 RTKTVEELRELESRLSNAEQTP-MFDIEP---VDRQETVAAAEAARAVEV Mflv_4188|M.gilvum_PYR-GCK RNRTVSELAELELRLQNAQREP-MFDAEV---VDRTEFTAAAEAARSAEV Mvan_2175|M.vanbaalenii_PYR-1 RNRTVEELAELESRLHNAQQEP-MFDVEV---VDRTEFTAAAEAARSAEV MMAR_1785|M.marinum_M RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV MUL_2033|M.ulcerans_Agy99 RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV MAV_3777|M.avium_104 RTQTVAEVTELENRLRNAQETPQEPAAEP---VNRQQIAAATDAARSAEV Mb2946c|M.bovis_AF2122/97 RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV Rv2922c|M.tuberculosis_H37Rv RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV MLBr_01629|M.leprae_Br4923 RVSILEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEV MAB_3246c|M.abscessus_ATCC_199 RATTLEELAEVESRLRNAEEAPNLFDDEP---LDRDDMAIELEEARSVEI TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQRAREAREYAARV Mflv_4188|M.gilvum_PYR-GCK EARLSVRTAEERANAVRGRADSLRRAAVAEREARVRAQRAREARVHAAAV Mvan_2175|M.vanbaalenii_PYR-1 EARLAVRTAEERANAVRGRADSLRRAAVAEREARARAQRAREARVQAAAV MMAR_1785|M.marinum_M EARLTVRTAEERANALRGRADSLRRAAAAEREARVRAELARAVRLRSAAV MUL_2033|M.ulcerans_Agy99 EARLTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAAV MAV_3777|M.avium_104 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQAREARLRAAAV Mb2946c|M.bovis_AF2122/97 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV Rv2922c|M.tuberculosis_H37Rv EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV MLBr_01629|M.leprae_Br4923 EALLAVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAV MAB_3246c|M.abscessus_ATCC_199 EARLAVRTSEERVNSVRGKADSLRRAAVAEREARARAARAAAARMRAAAV TH_1649|M.thermoresistible__bu -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 AAAVSECGRQIAGKLSAVVAAAARSRDELATERQLRVNALGEIREEVTAL Mflv_4188|M.gilvum_PYR-GCK AAAVAESGRAVAQRLADAVSVASRIRDEVAAERQVRAGALTKAREEVNEL Mvan_2175|M.vanbaalenii_PYR-1 AAAVAESGRLVAQRLADAVAVASRIRDEVAAERHVRAAALTKAREEVAEL MMAR_1785|M.marinum_M AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL MUL_2033|M.ulcerans_Agy99 AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL MAV_3777|M.avium_104 AAAVADSGRLLATRLNAVVAAASRIRDALAAERQQRATAMTAVRDEVNAL Mb2946c|M.bovis_AF2122/97 AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL Rv2922c|M.tuberculosis_H37Rv AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL MLBr_01629|M.leprae_Br4923 AAAVTDCGQLLASRLTQAVDLAARHRDALATERQQRSVAIAAVRYEVNTL MAB_3246c|M.abscessus_ATCC_199 AAAVAESGRMVAARLEHVVAAASARRDELSATRAQHTSAIGAVRDQVREL TH_1649|M.thermoresistible__bu -------------------------------------MSADDLIAEYGPH MSMEG_2423|M.smegmatis_MC2_155 NNRINTLTDALHRDEMAKAQAQLRIEQLEAQVLEQFGMSAGDLVAEYGPQ Mflv_4188|M.gilvum_PYR-GCK TARITALTDALHRDEVAKAQAALRIEQLEQQVLEQFGMAVADLVAEYGPD Mvan_2175|M.vanbaalenii_PYR-1 TARIAALTDSLHRDEVAKAQAALRIEQLEQQVLEQFGIAVADLIAEYGPD MMAR_1785|M.marinum_M SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD MUL_2033|M.ulcerans_Agy99 SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD MAV_3777|M.avium_104 SARVAALTDSLHRDEVANAQAALRIEQLEQMVLEQFGMAPADLIAEYGPH Mb2946c|M.bovis_AF2122/97 SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH Rv2922c|M.tuberculosis_H37Rv SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH MLBr_01629|M.leprae_Br4923 RVRLATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDLIAEYGPQ MAB_3246c|M.abscessus_ATCC_199 TQAQTRLTDALHRDEVAKAQAALRIEQLSEQVLEQFGMAADDLIAEYGPH :: **::****. TH_1649|M.thermoresistible__bu VPLPPTELEMAEYEQALERGEQVTKPAPMPYDRATQERRAKRAERELAEL MSMEG_2423|M.smegmatis_MC2_155 VALPPSELEMAEYEQAKERGEQVTAPAPMPFDRATQERRAKRAERELAEL Mflv_4188|M.gilvum_PYR-GCK VALPPSELEMAEYEQARERGEQVTAPAPMPYDRPTQERRAKRAERELKEL Mvan_2175|M.vanbaalenii_PYR-1 VPLPPSELEMAEYEQAKERGEQVTAPAPMPYDRPTQERRAKRADKELREL MMAR_1785|M.marinum_M VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL MUL_2033|M.ulcerans_Agy99 VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL MAV_3777|M.avium_104 IALPPSELEMAEYEQAKERGEQVFAPAPIPFDRPTQERRAKRAERELAEL Mb2946c|M.bovis_AF2122/97 VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL Rv2922c|M.tuberculosis_H37Rv VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL MLBr_01629|M.leprae_Br4923 VALLPTELEMAEFQQARERGEQVTSPAPMPYDRATQERRAKRAERELAEL MAB_3246c|M.abscessus_ATCC_199 IELPPSQQEIDEYEQARERGEQVSAPLPMPFDRDTQERRAKRAEKDLREL : * *:: *: *::** ****** * *:*:** **:******:: * ** TH_1649|M.thermoresistible__bu GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDQRILQLF MSMEG_2423|M.smegmatis_MC2_155 GRVNPLALEEFAALEERYNFLSTQLEDVKAARADLLDVIADVDNRILQVF Mflv_4188|M.gilvum_PYR-GCK GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIAEVDTRILQVF Mvan_2175|M.vanbaalenii_PYR-1 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDSRILQVF MMAR_1785|M.marinum_M GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF MUL_2033|M.ulcerans_Agy99 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF MAV_3777|M.avium_104 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVDEVDARILQVF Mb2946c|M.bovis_AF2122/97 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF Rv2922c|M.tuberculosis_H37Rv GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF MLBr_01629|M.leprae_Br4923 GRVNPLALEEFAALEERYNFLSTQLEDVKGARKDLLDVVAEVDARILQVF MAB_3246c|M.abscessus_ATCC_199 GKVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDERILQVF *:***************************.** ***.*: :** ****:* TH_1649|M.thermoresistible__bu AEAYTDVEREFREVFATLFPGGEGRLLLTDPNDMLTTGVEVEARPPGKKI MSMEG_2423|M.smegmatis_MC2_155 TEAYADVEREFEQVFATLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI Mflv_4188|M.gilvum_PYR-GCK TEAYMDVEREFTQVFSTLFPGGEGRLLLTNPSDMLTTGIEVEARPPGKKI Mvan_2175|M.vanbaalenii_PYR-1 TEAYMDVEREFTQVFSTLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI MMAR_1785|M.marinum_M SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV MUL_2033|M.ulcerans_Agy99 SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV MAV_3777|M.avium_104 SEAYTDVEREFSDVFGVLFPGGEGRLRLTDPSNMLTTGIEVEARPPGKKI Mb2946c|M.bovis_AF2122/97 NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI Rv2922c|M.tuberculosis_H37Rv NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI MLBr_01629|M.leprae_Br4923 SDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIEVEARPSGKKV MAB_3246c|M.abscessus_ATCC_199 TEAYADVEREFKGVFSSLFPGGEGRLVLTDPNDMLTTGIEVEARPPGKKV :*: ****** ** ********* ** *.:*****:******.***: TH_1649|M.thermoresistible__bu KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS MSMEG_2423|M.smegmatis_MC2_155 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS Mflv_4188|M.gilvum_PYR-GCK KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS Mvan_2175|M.vanbaalenii_PYR-1 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS MMAR_1785|M.marinum_M SRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIG MUL_2033|M.ulcerans_Agy99 SRLSLLSGGEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIG MAV_3777|M.avium_104 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIS Mb2946c|M.bovis_AF2122/97 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS Rv2922c|M.tuberculosis_H37Rv TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS MLBr_01629|M.leprae_Br4923 SRLSLLSGGEKSLIAVAMLVAIFKARPSPFYIMDEVEAALDDVNLCRLIG MAB_3246c|M.abscessus_ATCC_199 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLQRLIG .**********:* ***:*****:*******:**********.** **:. TH_1649|M.thermoresistible__bu LFEQLRERSQLIVITHQKPTMEVADALYGVTMRDDGITTVISQRLRGQ-- MSMEG_2423|M.smegmatis_MC2_155 LFEQLREKSQLIVITHQKPTMEIADALYGVTMRGDGITTVISQRMRGQ-- Mflv_4188|M.gilvum_PYR-GCK LFEQLRERSQLIVITHQKPTMEVADALYGVTMQGDGITTVISQRMRGQ-- Mvan_2175|M.vanbaalenii_PYR-1 LFEQLRERSQLIVITHQKPTMEVADALYGVTMRGDGITTVISQRMRGQ-- MMAR_1785|M.marinum_M LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV MUL_2033|M.ulcerans_Agy99 LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV MAV_3777|M.avium_104 LFELLRARSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRMRGQQV Mb2946c|M.bovis_AF2122/97 LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV Rv2922c|M.tuberculosis_H37Rv LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV MLBr_01629|M.leprae_Br4923 VFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAVISQRMRGQQV MAB_3246c|M.abscessus_ATCC_199 LFEQLREKSQLIVITHQKPTMEVADALYGVSMRDDGITQVVSQRMRGLET :** ** :**:*:*********:**:****:*:.**** *:***:** TH_1649|M.thermoresistible__bu -ELVAQPG MSMEG_2423|M.smegmatis_MC2_155 -ELVSNPS Mflv_4188|M.gilvum_PYR-GCK -ELVTSSS Mvan_2175|M.vanbaalenii_PYR-1 -ELVASPS MMAR_1785|M.marinum_M DRLVANSS MUL_2033|M.ulcerans_Agy99 DRLVANSS MAV_3777|M.avium_104 DQLVTT-- Mb2946c|M.bovis_AF2122/97 DQLVTNSS Rv2922c|M.tuberculosis_H37Rv DQLVTNSS MLBr_01629|M.leprae_Br4923 ESLVTSSS MAB_3246c|M.abscessus_ATCC_199 -QLASQNA *.: