For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1649 (smc)

annotation: PROBABLE CHROMOSOME PARTITION PROTEIN SMC
coordinates: 3211156 - 3211962
length: 269

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1649smc-100% (269)PROBABLE CHROMOSOME PARTITION PROTEIN SMC
M. thermoresistible (build 8)TH_0007-2e-0523.90% (251) conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2946csmc1e-12584.79% (263) chromosome partition protein Smc
M. gilvum PYR-GCKMflv_4188-1e-13290.53% (264) chromosome segregation protein SMC
M. tuberculosis H37RvRv2922csmc1e-12584.79% (263) chromosome partition protein Smc
M. leprae Br4923MLBr_01629smc1e-12284.17% (259) putative cell division protein
M. abscessus ATCC 19977MAB_3246c-1e-12885.50% (262) chromosome partition protein Smc
M. marinum MMMAR_1785smc1e-12483.65% (263) chromosome partition protein Smc
M. avium 104MAV_3777smc1e-12584.79% (263) chromosome segregation protein SMC
M. smegmatis MC2 155MSMEG_2423smc1e-13691.39% (267) chromosome segregation protein SMC
M. ulcerans Agy99MUL_2033smc1e-12483.27% (263) chromosome partition protein Smc
M. vanbaalenii PYR-1Mvan_2175-1e-13592.40% (263) chromosome segregation protein SMC

CLUSTAL 2.0.9 multiple sequence alignment


TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
Mflv_4188|M.gilvum_PYR-GCK          MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
Mvan_2175|M.vanbaalenii_PYR-1       MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
MMAR_1785|M.marinum_M               MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MUL_2033|M.ulcerans_Agy99           MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MAV_3777|M.avium_104                MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
Mb2946c|M.bovis_AF2122/97           MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
Rv2922c|M.tuberculosis_H37Rv        MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MLBr_01629|M.leprae_Br4923          MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MAB_3246c|M.abscessus_ATCC_199      ----------------------------------------MDALTWVMGE
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
Mflv_4188|M.gilvum_PYR-GCK          QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
Mvan_2175|M.vanbaalenii_PYR-1       QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
MMAR_1785|M.marinum_M               QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYTEVSI
MUL_2033|M.ulcerans_Agy99           QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALPIEYTEVSI
MAV_3777|M.avium_104                QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYSEVSI
Mb2946c|M.bovis_AF2122/97           QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI
Rv2922c|M.tuberculosis_H37Rv        QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI
MLBr_01629|M.leprae_Br4923          QGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSI
MAB_3246c|M.abscessus_ATCC_199      QGAKALRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDHALPIEYSEVSI
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      TRRMFRDGAGEYEINGASCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL
Mflv_4188|M.gilvum_PYR-GCK          TRRMFRDGAGEYEINGSRCRLADVQELLSDSGIGREMHVIVGQGKLSEIL
Mvan_2175|M.vanbaalenii_PYR-1       TRRMFRDGAGEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL
MMAR_1785|M.marinum_M               TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MUL_2033|M.ulcerans_Agy99           TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MAV_3777|M.avium_104                TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
Mb2946c|M.bovis_AF2122/97           TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL
Rv2922c|M.tuberculosis_H37Rv        TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL
MLBr_01629|M.leprae_Br4923          TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDQIL
MAB_3246c|M.abscessus_ATCC_199      TRRMFRDGAGEYEINGQTCRLMDVQELLSDSGIGREMHVIVGQGRLSQIL
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR
Mflv_4188|M.gilvum_PYR-GCK          ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR
Mvan_2175|M.vanbaalenii_PYR-1       ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMSANLARLTDLTTELRR
MMAR_1785|M.marinum_M               QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MUL_2033|M.ulcerans_Agy99           QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MAV_3777|M.avium_104                QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
Mb2946c|M.bovis_AF2122/97           QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR
Rv2922c|M.tuberculosis_H37Rv        QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR
MLBr_01629|M.leprae_Br4923          QSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTELRR
MAB_3246c|M.abscessus_ATCC_199      ESRPEDRRAFVEEAAGVLKHRKRKEKAVRKLESMAANLARLTDLTTELRR
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      QLKPLGRQAEMARRAATIQADLRDARLRLAADDLVRRQVEFQNTNQAETA
Mflv_4188|M.gilvum_PYR-GCK          QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVARKAEFDDTDQAETT
Mvan_2175|M.vanbaalenii_PYR-1       QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVTRKAEFDDTNQAETT
MMAR_1785|M.marinum_M               QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT
MUL_2033|M.ulcerans_Agy99           QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT
MAV_3777|M.avium_104                QLKPLGRQAEVARRAQTIQADLRDARLRLAADDLVNRRGEREAIFEAEAA
Mb2946c|M.bovis_AF2122/97           QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA
Rv2922c|M.tuberculosis_H37Rv        QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA
MLBr_01629|M.leprae_Br4923          QLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEAETM
MAB_3246c|M.abscessus_ATCC_199      QLKPLGRQAEVARRAATVQADLRDARLRLAADDLVSRRADFDGTNDAETA
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      LRKEHEELTVRLQSATVELQAHEAAVAELTRRAEAAQQTWFRASALAERV
Mflv_4188|M.gilvum_PYR-GCK          LRREHDELTERLQERAAELDAHETAVEDLSERADAAQQRWFRLSALAERV
Mvan_2175|M.vanbaalenii_PYR-1       LRREHDELTERMEARTLELDAHESAVADLSERADAAQQRWFRLSALAERV
MMAR_1785|M.marinum_M               MRREHDEAAARLTVAAEELAAHEAALAELTSRAESVQHTWFGLSALAERV
MUL_2033|M.ulcerans_Agy99           MRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFGLSALAERV
MAV_3777|M.avium_104                MRREHDEASARLAVASEELAAHEKALGELSGRAESVQQTWFALSALAERV
Mb2946c|M.bovis_AF2122/97           MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV
Rv2922c|M.tuberculosis_H37Rv        MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV
MLBr_01629|M.leprae_Br4923          MRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLVERV
MAB_3246c|M.abscessus_ATCC_199      LRKEHAEITDRLEVATALLAEHETALGELLPQAELAQQTWFRLSALAERV
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      GATVRIATDRAQMLDSEPEMSSGRDP---DALEAEAEEVAELEAQLLDEL
Mflv_4188|M.gilvum_PYR-GCK          SATVRIASERAQHLDGDPDFSAGPDP---DELEAQADAVAEQEQQLLDEL
Mvan_2175|M.vanbaalenii_PYR-1       SATVRIASERAQHLDAEPDFSAGPDP---DELEAQADAVAEQEQLLLDEL
MMAR_1785|M.marinum_M               GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL
MUL_2033|M.ulcerans_Agy99           GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL
MAV_3777|M.avium_104                AATVRIASERAQHLDLGPVTAGDTDP---DALDAEAERVAAAEQQLLAEL
Mb2946c|M.bovis_AF2122/97           DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL
Rv2922c|M.tuberculosis_H37Rv        DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL
MLBr_01629|M.leprae_Br4923          SATIRIAGERAYHLDVDPATPSDTDP---DVLEAEAQQMEVAEQQLLAEL
MAB_3246c|M.abscessus_ATCC_199      SATVRIAGERASHLDEVAAAPTGPDP---EELEAQAERVAEQERLLIAQL
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      SEARIALETARAELAEREQIAADAERAHMAAARAEADRREGLARLAGQVD
Mflv_4188|M.gilvum_PYR-GCK          AESQERLEAAREELAEREQAAAEAERAHMAAARAEADRREGLARLSGQVD
Mvan_2175|M.vanbaalenii_PYR-1       AESQARLESARAELGEREQAAAEAERAHMAAARAEADRREGLARLSGQVD
MMAR_1785|M.marinum_M               AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE
MUL_2033|M.ulcerans_Agy99           AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE
MAV_3777|M.avium_104                AAARSRLETARAELAEREREAAEADRAHMAAVRAEADRREGLARLAGQVE
Mb2946c|M.bovis_AF2122/97           DAARARLDAARAERADRERRAAEADRAHLAAVREEADRREGLARLAGQVE
Rv2922c|M.tuberculosis_H37Rv        DAARARLDAARAELADRERRAAEADRAHLAAVREEADRREGLARLAGQVE
MLBr_01629|M.leprae_Br4923          AVARTQLEAARAELADRERHAVEADKAHLEAVRAEADRREGLALLAGQVE
MAB_3246c|M.abscessus_ATCC_199      ETVTEQLATAKAELSARESAVAQAQRQHMAAVAAEADRREGLARLTGQVD
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      TMRTRVESIDEGVLRLSVSIEEAAAKAEHAQAEFEDVQSRVGELDAGEVG
Mflv_4188|M.gilvum_PYR-GCK          TMRTRVESVDETVARLTANIDDAAARAQLTQAEFETVQARVGELDAGEVG
Mvan_2175|M.vanbaalenii_PYR-1       TMRTRVDSVDETVARLTASIDEAGARAQQTQAEFETVQGRVAELDSGEVG
MMAR_1785|M.marinum_M               TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG
MUL_2033|M.ulcerans_Agy99           TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG
MAV_3777|M.avium_104                TMRARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELDQGEVG
Mb2946c|M.bovis_AF2122/97           TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG
Rv2922c|M.tuberculosis_H37Rv        TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG
MLBr_01629|M.leprae_Br4923          TMRARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEVH
MAB_3246c|M.abscessus_ATCC_199      TMRTRLESIDGQAQRLTESIVEATVRGEAAQTEFDTVKARVAELDQGEVG
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      LDEHHDRTVAALRLADERVAELQAAERAAERQVASLRARIEALSVGLDRR
Mflv_4188|M.gilvum_PYR-GCK          LDEHHDRSVAALRLADERVAELLAAERAAERQVASLQARIDALSVGLDRR
Mvan_2175|M.vanbaalenii_PYR-1       LDEHHDRTVAALRLADERVTELQAAERAAERRVASLQARIDALSVGLDRK
MMAR_1785|M.marinum_M               LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIEALSVGLDRK
MUL_2033|M.ulcerans_Agy99           LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSVGLDRK
MAV_3777|M.avium_104                LDEHHERTVAALRLADERVAELQAAERDAERKVASLRARIDALAVGLERK
Mb2946c|M.bovis_AF2122/97           LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK
Rv2922c|M.tuberculosis_H37Rv        LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK
MLBr_01629|M.leprae_Br4923          LDEQHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLERK
MAB_3246c|M.abscessus_ATCC_199      LDEHHERSISSLSIANERVAELQSAERQAERQIASLKARIDALAIGLERK
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      DGAAWLQKNHSGGGLFGSIGDFLRVQPGYEVAVAAVLGAAADALAAENFG
Mflv_4188|M.gilvum_PYR-GCK          DGAAWLQENHSGAGLFGSIANLVKVRAGHEAAIAAMLGAAADALAAEDFG
Mvan_2175|M.vanbaalenii_PYR-1       DGAAWLKENRSGAGLFDSLANLVKVRPGHEAAIAAVLGAAADALAAENSG
MMAR_1785|M.marinum_M               DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG
MUL_2033|M.ulcerans_Agy99           DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG
MAV_3777|M.avium_104                DGTAWLTENHSGAGILGPMAKLVKVRSGYEAAVAAVLGSAADALAADGLG
Mb2946c|M.bovis_AF2122/97           DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT
Rv2922c|M.tuberculosis_H37Rv        DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT
MLBr_01629|M.leprae_Br4923          DGAAWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSLG
MAB_3246c|M.abscessus_ATCC_199      DGSAWLAENRSGAGIFGSIAQLVKVRPGYQGAIATAMGPAADAVAAENPA
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      AAAAAVAALKESDGGRAAIVLGDWN---AIGSSPQAALPPGATWATDLVS
Mflv_4188|M.gilvum_PYR-GCK          AARAAVAALKESDGGRAALVLGDWP---AQEAVTG-QLPAGAAWAVDLVE
Mvan_2175|M.vanbaalenii_PYR-1       AARDALAALKESDGGRAAIVLGDWP---ARTPATG-QLPAGAAWAVDLVD
MMAR_1785|M.marinum_M               AARSAVTALKQADGGRAALVLGDWPDANDHRAAG--GLPSGTLWALDLIE
MUL_2033|M.ulcerans_Agy99           AARSAVTALKQADGGRAALVLGDWPDAHDHRAAG--GLPSGTLWALDLIE
MAV_3777|M.avium_104                AARSALGALKQADGGRAALVLGDWP--ADPPAPQ--PAPAGALWALDLID
Mb2946c|M.bovis_AF2122/97           AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE
Rv2922c|M.tuberculosis_H37Rv        AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE
MLBr_01629|M.leprae_Br4923          AARSALTALKEADAGRATLVLADWLADAGPACVT--GLPDGAQRALDLIE
MAB_3246c|M.abscessus_ATCC_199      AAHEAVKALKSSDGGRAAIVFGDWPAHTGARPAVT--LPPGAHWANDLVE
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      VPDRLRGAVTAMLTGVAVVPDMAAGLALVSSRPELRAVTTEGDLVGPGWV
Mflv_4188|M.gilvum_PYR-GCK          PADRVRGAVTAMLSGVAVVENLTAALDLVAAQPRLRAVTADGDLVGAGWV
Mvan_2175|M.vanbaalenii_PYR-1       PAPRIQGAVTAMLGGVAVVGDLTAALELVAAQPELRAVTADGDLVGAGWV
MMAR_1785|M.marinum_M               VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV
MUL_2033|M.ulcerans_Agy99           VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV
MAV_3777|M.avium_104                APERLRGAITAMLSGVAVVDDLDRALALVAEHPRLRAVTLDGDLVGAGWV
Mb2946c|M.bovis_AF2122/97           SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV
Rv2922c|M.tuberculosis_H37Rv        SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV
MLBr_01629|M.leprae_Br4923          APPWLQGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWV
MAB_3246c|M.abscessus_ATCC_199      APQRLAAAVSAMLASVVVVDELGAAIDVVLANPLLRAVTIDGDRVGAGWV
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      SGGSDRKPSTLEIASEIDKARAELEQAERQTSELGAALSGALAEQSARQD
Mflv_4188|M.gilvum_PYR-GCK          SGGSDRKPSTLEIQSEVDRARSELVDAERRTGELSAALSGALAEQAARQD
Mvan_2175|M.vanbaalenii_PYR-1       SGGSDRKPSTLEITSEVDKARAELVDAERQTGELSAALSGALAEQAARQD
MMAR_1785|M.marinum_M               SGGSDRKPSTLEITSEIDKARSELAAAEVRVAELGAALSGALTDQTARQD
MUL_2033|M.ulcerans_Agy99           SGGSDRKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTARQD
MAV_3777|M.avium_104                SGGSDRKLSTLEVTSEIDKASAELAAAEAQVAQLSAALSGALAEQAARQD
Mb2946c|M.bovis_AF2122/97           SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSAGQD
Rv2922c|M.tuberculosis_H37Rv        SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSARQD
MLBr_01629|M.leprae_Br4923          SGGSGRRLSTLEVTSEIDKAGAELAAAEAHMAQLNAALSGALSEQVAHSD
MAB_3246c|M.abscessus_ATCC_199      AGGSDKKQSTLEVQAAIEAAREELRATETQVGEISAALAGALAEQTARQD
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      AAEQALAALNESDAAISAIYEQLARLGQEARGAHQEWQRLIKQRDELEAG
Mflv_4188|M.gilvum_PYR-GCK          AAEHALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIRQRDEMEAG
Mvan_2175|M.vanbaalenii_PYR-1       AAEQALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIKQRDELEAG
MMAR_1785|M.marinum_M               AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG
MUL_2033|M.ulcerans_Agy99           AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG
MAV_3777|M.avium_104                SAEQALAALNESDSAISGMYEQLGRLGQEARTSEDEWSRLLRQREELEAG
Mb2946c|M.bovis_AF2122/97           AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV
Rv2922c|M.tuberculosis_H37Rv        AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV
MLBr_01629|M.leprae_Br4923          ATEQALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEAR
MAB_3246c|M.abscessus_ATCC_199      TAEQALAALNESDAAISAVYEQLGRVGQEVRAAAEEVKKLTLQRDQLERG
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      RTKTVEELRELESRLSNAEQTP-MFDIEP---VDRQETVAAAEAARAVEV
Mflv_4188|M.gilvum_PYR-GCK          RNRTVSELAELELRLQNAQREP-MFDAEV---VDRTEFTAAAEAARSAEV
Mvan_2175|M.vanbaalenii_PYR-1       RNRTVEELAELESRLHNAQQEP-MFDVEV---VDRTEFTAAAEAARSAEV
MMAR_1785|M.marinum_M               RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV
MUL_2033|M.ulcerans_Agy99           RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV
MAV_3777|M.avium_104                RTQTVAEVTELENRLRNAQETPQEPAAEP---VNRQQIAAATDAARSAEV
Mb2946c|M.bovis_AF2122/97           RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV
Rv2922c|M.tuberculosis_H37Rv        RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV
MLBr_01629|M.leprae_Br4923          RVSILEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEV
MAB_3246c|M.abscessus_ATCC_199      RATTLEELAEVESRLRNAEEAPNLFDDEP---LDRDDMAIELEEARSVEI
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQRAREAREYAARV
Mflv_4188|M.gilvum_PYR-GCK          EARLSVRTAEERANAVRGRADSLRRAAVAEREARVRAQRAREARVHAAAV
Mvan_2175|M.vanbaalenii_PYR-1       EARLAVRTAEERANAVRGRADSLRRAAVAEREARARAQRAREARVQAAAV
MMAR_1785|M.marinum_M               EARLTVRTAEERANALRGRADSLRRAAAAEREARVRAELARAVRLRSAAV
MUL_2033|M.ulcerans_Agy99           EARLTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAAV
MAV_3777|M.avium_104                EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQAREARLRAAAV
Mb2946c|M.bovis_AF2122/97           EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV
Rv2922c|M.tuberculosis_H37Rv        EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV
MLBr_01629|M.leprae_Br4923          EALLAVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAV
MAB_3246c|M.abscessus_ATCC_199      EARLAVRTSEERVNSVRGKADSLRRAAVAEREARARAARAAAARMRAAAV
                                                                                      

TH_1649|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2423|M.smegmatis_MC2_155      AAAVSECGRQIAGKLSAVVAAAARSRDELATERQLRVNALGEIREEVTAL
Mflv_4188|M.gilvum_PYR-GCK          AAAVAESGRAVAQRLADAVSVASRIRDEVAAERQVRAGALTKAREEVNEL
Mvan_2175|M.vanbaalenii_PYR-1       AAAVAESGRLVAQRLADAVAVASRIRDEVAAERHVRAAALTKAREEVAEL
MMAR_1785|M.marinum_M               AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL
MUL_2033|M.ulcerans_Agy99           AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL
MAV_3777|M.avium_104                AAAVADSGRLLATRLNAVVAAASRIRDALAAERQQRATAMTAVRDEVNAL
Mb2946c|M.bovis_AF2122/97           AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL
Rv2922c|M.tuberculosis_H37Rv        AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL
MLBr_01629|M.leprae_Br4923          AAAVTDCGQLLASRLTQAVDLAARHRDALATERQQRSVAIAAVRYEVNTL
MAB_3246c|M.abscessus_ATCC_199      AAAVAESGRMVAARLEHVVAAASARRDELSATRAQHTSAIGAVRDQVREL
                                                                                      

TH_1649|M.thermoresistible__bu      -------------------------------------MSADDLIAEYGPH
MSMEG_2423|M.smegmatis_MC2_155      NNRINTLTDALHRDEMAKAQAQLRIEQLEAQVLEQFGMSAGDLVAEYGPQ
Mflv_4188|M.gilvum_PYR-GCK          TARITALTDALHRDEVAKAQAALRIEQLEQQVLEQFGMAVADLVAEYGPD
Mvan_2175|M.vanbaalenii_PYR-1       TARIAALTDSLHRDEVAKAQAALRIEQLEQQVLEQFGIAVADLIAEYGPD
MMAR_1785|M.marinum_M               SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD
MUL_2033|M.ulcerans_Agy99           SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD
MAV_3777|M.avium_104                SARVAALTDSLHRDEVANAQAALRIEQLEQMVLEQFGMAPADLIAEYGPH
Mb2946c|M.bovis_AF2122/97           SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH
Rv2922c|M.tuberculosis_H37Rv        SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH
MLBr_01629|M.leprae_Br4923          RVRLATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDLIAEYGPQ
MAB_3246c|M.abscessus_ATCC_199      TQAQTRLTDALHRDEVAKAQAALRIEQLSEQVLEQFGMAADDLIAEYGPH
                                                                         ::  **::****.

TH_1649|M.thermoresistible__bu      VPLPPTELEMAEYEQALERGEQVTKPAPMPYDRATQERRAKRAERELAEL
MSMEG_2423|M.smegmatis_MC2_155      VALPPSELEMAEYEQAKERGEQVTAPAPMPFDRATQERRAKRAERELAEL
Mflv_4188|M.gilvum_PYR-GCK          VALPPSELEMAEYEQARERGEQVTAPAPMPYDRPTQERRAKRAERELKEL
Mvan_2175|M.vanbaalenii_PYR-1       VPLPPSELEMAEYEQAKERGEQVTAPAPMPYDRPTQERRAKRADKELREL
MMAR_1785|M.marinum_M               VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL
MUL_2033|M.ulcerans_Agy99           VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL
MAV_3777|M.avium_104                IALPPSELEMAEYEQAKERGEQVFAPAPIPFDRPTQERRAKRAERELAEL
Mb2946c|M.bovis_AF2122/97           VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL
Rv2922c|M.tuberculosis_H37Rv        VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL
MLBr_01629|M.leprae_Br4923          VALLPTELEMAEFQQARERGEQVTSPAPMPYDRATQERRAKRAERELAEL
MAB_3246c|M.abscessus_ATCC_199      IELPPSQQEIDEYEQARERGEQVSAPLPMPFDRDTQERRAKRAEKDLREL
                                    : * *:: *: *::** ******  * *:*:** **:******:: * **

TH_1649|M.thermoresistible__bu      GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDQRILQLF
MSMEG_2423|M.smegmatis_MC2_155      GRVNPLALEEFAALEERYNFLSTQLEDVKAARADLLDVIADVDNRILQVF
Mflv_4188|M.gilvum_PYR-GCK          GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIAEVDTRILQVF
Mvan_2175|M.vanbaalenii_PYR-1       GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDSRILQVF
MMAR_1785|M.marinum_M               GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF
MUL_2033|M.ulcerans_Agy99           GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF
MAV_3777|M.avium_104                GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVDEVDARILQVF
Mb2946c|M.bovis_AF2122/97           GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF
Rv2922c|M.tuberculosis_H37Rv        GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF
MLBr_01629|M.leprae_Br4923          GRVNPLALEEFAALEERYNFLSTQLEDVKGARKDLLDVVAEVDARILQVF
MAB_3246c|M.abscessus_ATCC_199      GKVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDERILQVF
                                    *:***************************.** ***.*: :** ****:*

TH_1649|M.thermoresistible__bu      AEAYTDVEREFREVFATLFPGGEGRLLLTDPNDMLTTGVEVEARPPGKKI
MSMEG_2423|M.smegmatis_MC2_155      TEAYADVEREFEQVFATLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI
Mflv_4188|M.gilvum_PYR-GCK          TEAYMDVEREFTQVFSTLFPGGEGRLLLTNPSDMLTTGIEVEARPPGKKI
Mvan_2175|M.vanbaalenii_PYR-1       TEAYMDVEREFTQVFSTLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI
MMAR_1785|M.marinum_M               SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV
MUL_2033|M.ulcerans_Agy99           SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV
MAV_3777|M.avium_104                SEAYTDVEREFSDVFGVLFPGGEGRLRLTDPSNMLTTGIEVEARPPGKKI
Mb2946c|M.bovis_AF2122/97           NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI
Rv2922c|M.tuberculosis_H37Rv        NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI
MLBr_01629|M.leprae_Br4923          SDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIEVEARPSGKKV
MAB_3246c|M.abscessus_ATCC_199      TEAYADVEREFKGVFSSLFPGGEGRLVLTDPNDMLTTGIEVEARPPGKKV
                                     :*: ******  **  ********* ** *.:*****:******.***:

TH_1649|M.thermoresistible__bu      KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
MSMEG_2423|M.smegmatis_MC2_155      KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
Mflv_4188|M.gilvum_PYR-GCK          KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
Mvan_2175|M.vanbaalenii_PYR-1       KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
MMAR_1785|M.marinum_M               SRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIG
MUL_2033|M.ulcerans_Agy99           SRLSLLSGGEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIG
MAV_3777|M.avium_104                TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIS
Mb2946c|M.bovis_AF2122/97           TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS
Rv2922c|M.tuberculosis_H37Rv        TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS
MLBr_01629|M.leprae_Br4923          SRLSLLSGGEKSLIAVAMLVAIFKARPSPFYIMDEVEAALDDVNLCRLIG
MAB_3246c|M.abscessus_ATCC_199      KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLQRLIG
                                    .**********:* ***:*****:*******:**********.** **:.

TH_1649|M.thermoresistible__bu      LFEQLRERSQLIVITHQKPTMEVADALYGVTMRDDGITTVISQRLRGQ--
MSMEG_2423|M.smegmatis_MC2_155      LFEQLREKSQLIVITHQKPTMEIADALYGVTMRGDGITTVISQRMRGQ--
Mflv_4188|M.gilvum_PYR-GCK          LFEQLRERSQLIVITHQKPTMEVADALYGVTMQGDGITTVISQRMRGQ--
Mvan_2175|M.vanbaalenii_PYR-1       LFEQLRERSQLIVITHQKPTMEVADALYGVTMRGDGITTVISQRMRGQ--
MMAR_1785|M.marinum_M               LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV
MUL_2033|M.ulcerans_Agy99           LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV
MAV_3777|M.avium_104                LFELLRARSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRMRGQQV
Mb2946c|M.bovis_AF2122/97           LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV
Rv2922c|M.tuberculosis_H37Rv        LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV
MLBr_01629|M.leprae_Br4923          VFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAVISQRMRGQQV
MAB_3246c|M.abscessus_ATCC_199      LFEQLREKSQLIVITHQKPTMEVADALYGVSMRDDGITQVVSQRMRGLET
                                    :** ** :**:*:*********:**:****:*:.**** *:***:**   

TH_1649|M.thermoresistible__bu      -ELVAQPG
MSMEG_2423|M.smegmatis_MC2_155      -ELVSNPS
Mflv_4188|M.gilvum_PYR-GCK          -ELVTSSS
Mvan_2175|M.vanbaalenii_PYR-1       -ELVASPS
MMAR_1785|M.marinum_M               DRLVANSS
MUL_2033|M.ulcerans_Agy99           DRLVANSS
MAV_3777|M.avium_104                DQLVTT--
Mb2946c|M.bovis_AF2122/97           DQLVTNSS
Rv2922c|M.tuberculosis_H37Rv        DQLVTNSS
MLBr_01629|M.leprae_Br4923          ESLVTSSS
MAB_3246c|M.abscessus_ATCC_199      -QLASQNA
                                      *.: