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MATDIGSTPIEIRGLTKNFGSVRALDELDLTVREGEVHGFLGPNGAGKSTTIRILLGLVKADSGSVRLLG GNPWTDAVELHRQIAYVPGDVTLWPSLTGGEIIDLLARMRGGIDQDRRAELIERFGLDPHKKSRTYSKGN RQKVSLISAFSSRARLLLLDEPSSGLDPLMENVFQQCVDEARGRGVTVLLSSHILAETEALCERITIIRA GRTVESGSLASMRHLSRTSIKAEMIGDPGDLTRIQGVEDVTVDGNTLHVQVDSESLGELVRVLGEAGVRS LVSQPPTLEELFLRHYSVGPDGEAQHRSGTGVAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4220 | - | - | 100% (315) | antibiotic ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2263 | - | 1e-31 | 36.97% (211) | antibiotic ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2026 | - | 1e-30 | 31.14% (289) | antibiotic-transport ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1250c | - | 1e-146 | 82.90% (310) | tetronasin-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_2197 | - | 2e-94 | 59.11% (291) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1218c | - | 1e-145 | 82.58% (310) | tetronasin-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_00590 | - | 4e-32 | 34.21% (228) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1359c | - | 2e-97 | 62.63% (289) | ABC transporter ATP-binding protein |
| M. avium 104 | MAV_1362 | - | 1e-150 | 88.16% (304) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_5075 | - | 2e-93 | 59.45% (291) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_2745 | - | 6e-91 | 56.70% (291) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_1859 | - | 9e-32 | 36.97% (211) | antibiotic ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_4499 | - | 9e-97 | 59.80% (296) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1250c|M.bovis_AF2122/97 -MSADN----HQVPIEIRGLTKHFGSVRALDGLDLTVREGEVHGFLGPNG
Rv1218c|M.tuberculosis_H37Rv -MSADN----HQVPIEIRGLTKHFGSVRALDGLDLTVREGEVHGFLGPNG
MMAR_4220|M.marinum_M -MATDI----GSTPIEIRGLTKNFGSVRALDELDLTVREGEVHGFLGPNG
MAV_1362|M.avium_104 -MATD-----GFAPIEIRGLTKNFGAVRALDGLDLTVREGEVHGFLGPNG
Mflv_2197|M.gilvum_PYR-GCK -MPDTS------PVVEIRGLRKAFGRTQALDGLDLAVAPGDVTGFLGPNG
Mvan_4499|M.vanbaalenii_PYR-1 -MTDTG------FAVDIHGLRKSFGHTKALDGLDLTVAPGDVAGFLGPNG
MSMEG_5075|M.smegmatis_MC2_155 -MTRSS------VAVEIHGLTKSFGRTRALDGLDMTVPYGHIVGFLGPNG
TH_2745|M.thermoresistible__bu -MTTTSPRFDAEPAVEIHGLKKSFGRTRAVDGLDLRVERGSVAGFLGPNG
MAB_1359c|M.abscessus_ATCC_199 -MTYPN------LAVEIRGLTKLFGKTKALDGLDLSVAHGEVAGFLGPNG
MLBr_00590|M.leprae_Br4923 MSSACTVPETPEVVIRLRGVCKHYGSILAVSNLDLDIHSAEVLALLGPNG
MUL_1859|M.ulcerans_Agy99 -------------MVRLRGVGKQYGSVTAVSNLDLEVRAAEVMALLGPNG
: ::*: * :* *:. **: : . : .:*****
Mb1250c|M.bovis_AF2122/97 AGKSTTLRILLGLVKADGGSVRLLGGDPWTDAVDLHRHIAYVPGDVTLWP
Rv1218c|M.tuberculosis_H37Rv AGKSTTLRILLGLVKADGGSVRLLGGDPWTDAVDLHRHIAYVPGDVTLWP
MMAR_4220|M.marinum_M AGKSTTIRILLGLVKADSGSVRLLGGNPWTDAVELHRQIAYVPGDVTLWP
MAV_1362|M.avium_104 AGKSTTIRILLGLVKADGGTVRLLGGDPWTQAVELHRQIAYVPGDVTLWP
Mflv_2197|M.gilvum_PYR-GCK AGKSTAIRVLLGLLRADGGDVRLLGADPWRDAVALHRRIAYVPGDVTLWP
Mvan_4499|M.vanbaalenii_PYR-1 AGKSTTIRVLLGLLRADGGTVRLLGRDPWRDAVDLHRRIAYVPGDVTLWP
MSMEG_5075|M.smegmatis_MC2_155 AGKSTTIRVLLGLLRAERGTVRLLGGDPWHDAVELHRRIAYVPGDVMLWP
TH_2745|M.thermoresistible__bu SGKSTTIRVLLGLLRADGGTARLLGGDPWHDAVELHRRLAYVPGDVTLWP
MAB_1359c|M.abscessus_ATCC_199 AGKSTTIRVLLGLLRADAGTVQLLGGDPWVNAVDLHRLIAYVPGDVTLWP
MLBr_00590|M.leprae_Br4923 AGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQGGGGYP
MUL_1859|M.ulcerans_Agy99 AGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQGGGGYP
:**:*::.: *:::.: * .:** :* : . *: :. : . :*
Mb1250c|M.bovis_AF2122/97 SLTGGETIDLLARMRGGI--DNARRAELIERFGLDPTKKA--RTYSKGNR
Rv1218c|M.tuberculosis_H37Rv SLTGGETIDLLARMRGGI--DNARRAELIERFGLDPTKKA--RTYSKGNR
MMAR_4220|M.marinum_M SLTGGEIIDLLARMRGGI--DQDRRAELIERFGLDPHKKS--RTYSKGNR
MAV_1362|M.avium_104 SLTGGEIIDLLARMRGGI--DKRRRAELIERFDLDPHKKA--RTYSKGNR
Mflv_2197|M.gilvum_PYR-GCK NLTGMQAIDFLTALRGDG-VDTRRRDELIERFELDPHKKA--RTYSKGNR
Mvan_4499|M.vanbaalenii_PYR-1 NLTGMQAIDFLAALRGDGTVDTRRRDQLIERFELDPHKKA--RTYSKGNR
MSMEG_5075|M.smegmatis_MC2_155 NLTGMQAIDFLCGLRGDG-VDVRRRNQLIDRFELDPHKKA--RTYSKGNR
TH_2745|M.thermoresistible__bu NLTGGQAIDFLAGLRDNF--DTKRRDELIERFELDPDKKA--RTYSKGNR
MAB_1359c|M.abscessus_ATCC_199 NLTGGQAIDFLTRMLGTEHISIRRRNELIERFELDPTKKA--RTYSKGNR
MLBr_00590|M.leprae_Br4923 AARAGEMLNLVASYAADP----LDPEWLLETLGLTDVARTTYRRLSGGQQ
MUL_1859|M.ulcerans_Agy99 AARAGEMLDLVASYAADP----LDPRWLLDTLGLTDAARTTYRRLSGGQQ
. : :::: *:: : * :: * * *::
Mb1250c|M.bovis_AF2122/97 QKVSLISALSSHATLLLLDEPSSGLDPLMENVFQQCIGEARQRGVTVLLS
Rv1218c|M.tuberculosis_H37Rv QKVSLISALSSHATLLLLDEPSSGLDPLMENVFQQCIGEARQRGVTVLLS
MMAR_4220|M.marinum_M QKVSLISAFSSRARLLLLDEPSSGLDPLMENVFQQCVDEARGRGVTVLLS
MAV_1362|M.avium_104 QKVSLISAFSSRARLLLLDEPSSGLDPLMENVFQQCVAQARDRGTTVLLS
Mflv_2197|M.gilvum_PYR-GCK QKVAIVAAFSTRSELFILDEPTSGLDPLMEKTFQECVREVAGRGAAVLLS
Mvan_4499|M.vanbaalenii_PYR-1 QKVAIVAAFSTRSELFVLDEPTSGLDPLMEQAFQQCVHEVAGQGAAVLLS
MSMEG_5075|M.smegmatis_MC2_155 QKVAIIAAFSCEADLYILDEPTSGLDPLMEQAFQQCVTEVAGRGAAVLLS
TH_2745|M.thermoresistible__bu QKVALVAAFSTNAEIYILDEPTSGLDPLMDKAFQMCVREAADNGAAVLLS
MAB_1359c|M.abscessus_ATCC_199 QKVALIAAFCSDADLFILDEPTSGLDPLMETVFQECVAEVSTRGCAVLLS
MLBr_00590|M.leprae_Br4923 QRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDGVTVVLT
MUL_1859|M.ulcerans_Agy99 QRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVVLT
*:::: .:: . : .****::*:*. . : * :*:*:
Mb1250c|M.bovis_AF2122/97 SHILAETEALCEKVTIIRAGKTVESGSLDALRHLSRTSIKAEMIGDP---
Rv1218c|M.tuberculosis_H37Rv SHILAETEALCEKVTIIRAGKTVESGSLDALRHLSRTSIKAEMIGDP---
MMAR_4220|M.marinum_M SHILAETEALCERITIIRAGRTVESGSLASMRHLSRTSIKAEMIGDP---
MAV_1362|M.avium_104 SHILAETEALCERVTIIRAGKTIESGSLSSMRHLSRTSIKAEMTGDP---
Mflv_2197|M.gilvum_PYR-GCK SHILAEVEKLCDSVTIVRSGRTVRSGTLAQMRQFMRTTVTVRVRGDG---
Mvan_4499|M.vanbaalenii_PYR-1 SHILAEVEKLCDTVTIVRAGRTVRSGALAQMRHLMRTTVTARTRGDG---
MSMEG_5075|M.smegmatis_MC2_155 SHILAEVEKLCDDVTIIRSGRTVRSGTLAELRHLMRTTVTVRTHSDG---
TH_2745|M.thermoresistible__bu SHILAEVERLCDSVTIIRSGRTVRAGRLDELRHLMRTTVKVRTRAPI---
MAB_1359c|M.abscessus_ATCC_199 SHILAEVEKLCHRVTIVRAGRTVLSGSLAELRHFMRTSVTVRTLANP---
MLBr_00590|M.leprae_Br4923 THQLKEAEELADRLVIIDHGRMIAAGTPTELMHTG-AKDQLRFSAPPRLD
MUL_1859|M.ulcerans_Agy99 THQLKEAEELADRLVIIDHGVTVAEGTPSELMRSG-AKDQLRFTAPPRLD
:* * *.* *.. :.*: * : * : : :. . .
Mb1250c|M.bovis_AF2122/97 -----GDLSRIKGVEDISIEGTTVRAQVDSESLRELIQVLGHAGVRS--L
Rv1218c|M.tuberculosis_H37Rv -----GDLSQIKGVEDISIEGTTVRAQVDSESLRELIQVLGHAGVRS--L
MMAR_4220|M.marinum_M -----GDLTRIQGVEDVTVDGNTLHVQVDSESLGELVRVLGEAGVRS--L
MAV_1362|M.avium_104 -----GDLRRIKGVEDISIEGNTLRAQVDSESLGELIRVLGDAGVRS--L
Mflv_2197|M.gilvum_PYR-GCK -----RALVDAPYVHDLRTDDGALRFSVDRDHLDRAVLDLTALGIED--L
Mvan_4499|M.vanbaalenii_PYR-1 -----EHLRQAPYVHDLRSDDGHLRFSVDRDDLDRVMADLSGLGIDE--L
MSMEG_5075|M.smegmatis_MC2_155 -----RVLRDVPYVHDFDCRDGQLRFSVDRTDLEFVMEHLIDLGIDD--L
TH_2745|M.thermoresistible__bu -----DALRTAPYIHEFSTDDGLHTFSVDRTDLDRTMTELTTLGIEE--L
MAB_1359c|M.abscessus_ATCC_199 -----SGLKSIPQLRDVTIGGNRASFTVDRSDLDRTMEQLAGLGIVD--L
MLBr_00590|M.leprae_Br4923 LSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQINVLTTNM
MUL_1859|M.ulcerans_Agy99 LSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCARIDVLATDM
* :. :* * .: :
Mb1250c|M.bovis_AF2122/97 VSQPPTLEELFLRHYS-LGPEVA-AEQQVATP----
Rv1218c|M.tuberculosis_H37Rv VSQPPTLEELFLRHYS-LGPEVA-AEQQVATP----
MMAR_4220|M.marinum_M VSQPPTLEELFLRHYS-VGPDGE-AQHRSGTGVAAR
MAV_1362|M.avium_104 VSQPPTLEELFLRHYDTSGTDGERGAHEAEVSLS--
Mflv_2197|M.gilvum_PYR-GCK AVAPASLEDMFLQEYQGANR----------------
Mvan_4499|M.vanbaalenii_PYR-1 TVAPASLEDMFLREYQGAGR----------------
MSMEG_5075|M.smegmatis_MC2_155 TVTPASLEDMFLREYQGAVP----------------
TH_2745|M.thermoresistible__bu TVTPASLEDLFLREYQEVPR----------------
MAB_1359c|M.abscessus_ATCC_199 SVAPASLEELFMREYQGASR----------------
MLBr_00590|M.leprae_Br4923 RVEQHSLEDVFLDLTGRKLR----------------
MUL_1859|M.ulcerans_Agy99 RVEQRSLEDVFLDLTGRKLRS---------------
:**::*: