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M. thermoresistible (build 8) TH_3718 (-)

annotation: putative aldehyde dehydrogenase
coordinates: 326696 - 327673
length: 326

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3718--100% (326)putative aldehyde dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1430-7e-5135.91% (323) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_4594-1e-1330.14% (146) helix-turn-helix domain-containing protein
M. tuberculosis H37RvRv1395-7e-5135.91% (323) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2050-6e-1430.61% (147) putative HTH-type transcriptional regulator AraC
M. marinum MMMAR_3156-7e-1229.86% (144) AraC/XylS family transcriptional regulator
M. avium 104-----
M. smegmatis MC2 155-----
M. ulcerans Agy99MUL_4350-5e-0834.04% (94) AraC/XylS family transcriptional regulator
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1430|M.bovis_AF2122/97            --MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDP
Rv1395|M.tuberculosis_H37Rv         --MGHLPPPAEVRHPVYATRVLCEVANERGVPTADVLAGTAIEPADLDDP
TH_3718|M.thermoresistible__bu      ----------------VAAADLIDTAVEAGIPADRCLRGTWLTRSDLAAA
Mflv_4594|M.gilvum_PYR-GCK          MDWAQGARSVKFSNAGVPPVAFVQMLESQALDPDAVARLRTIMAREGTDE
MMAR_3156|M.marinum_M               ---------MNPNDAGVPPLAFVQMLESPAFDPDAVARLRNIMAREGTDE
MAB_2050|M.abscessus_ATCC_1997      ---------MKLDDSGMPALAFLQMLDSEALGHDASIALRSIMVREHVTE
MUL_4350|M.ulcerans_Agy99           ----------MSVVRGTGLSNYPNLVSELGGDPAALLRAAGVREQDVGNY
                                                           :   . .           :   :    

Mb1430|M.bovis_AF2122/97            DAVVG--ALDEITAVRRLLARLPDDAG--IGIDVGSRFALTHFGLFGFAV
Rv1395|M.tuberculosis_H37Rv         DAVVG--ALDEITAVRRLLARLPDDAG--IGIDVGSRFALTHFGLFGFAV
TH_3718|M.thermoresistible__bu      DRLIT--AEQELRIVRNVLAATEHPTA--LAGSAGARYQLPRAGFLGFAL
Mflv_4594|M.gilvum_PYR-GCK          ATLMQHDVQAPLRWFRDLYPDLDVDRATLLGFSFAGQAQLTSFGPLSVPL
MMAR_3156|M.marinum_M               ATLIQRDIQAPLRWFREAYPGLDIDQATLLGFALAEQAQLTSFGPLSVPL
MAB_2050|M.abscessus_ATCC_1997      SMLVGRDAQVPLRWFREIYSDFDCDQGTRLGFAFAEHAKLTSFGALSVPL
MUL_4350|M.ulcerans_Agy99           DAFIP-----VRAVIRAIETAAAATGTHDFGRQLAQRQGIEILGPVGVAA
                                      .:          .*   .         :.   . :  :   * .... 

Mb1430|M.bovis_AF2122/97            MSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRG
Rv1395|M.tuberculosis_H37Rv         MSCGTLRELLTIAMRYFALTTMHVDITLFETADDCLVELDASHLPADVRG
TH_3718|M.thermoresistible__bu      LSSNTLGDAIRVGIRFWRLTSVFERVTLEVNRQTTAIVLDDRDVPADVRQ
Mflv_4594|M.gilvum_PYR-GCK          VSAGSVAEIVEL-LTYLPLITTAINAQFRPNDQGLTVGLWGHTGDRALDC
MMAR_3156|M.marinum_M               VSAGSVAEIVEL-LTYLPLITTAVKAQFHPDDQGLTVGLWGHTSDRALDC
MAB_2050|M.abscessus_ATCC_1997      VSAGSVAEVVEL-LAYLPVITTALSPSFHSTERGLTIGLTGRTGDAGLNC
MUL_4350|M.ulcerans_Agy99           RTAATVADALMIFHTFMAAYSPAIHIEITPLARTQRSVVAIEIVPDDP--
                                     :. :: : : :   :    :      :          :           

Mb1430|M.bovis_AF2122/97            FFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVH
Rv1395|M.tuberculosis_H37Rv         FFIERDIAGIIATTTSFALPLAAKYADQVSAELAVDAELLRPLLELVPVH
TH_3718|M.thermoresistible__bu      FLVERDAATMVGVTP--AL-LGGPLPDGVRMSLRRRPNGDAAVEELV---
Mflv_4594|M.gilvum_PYR-GCK          LAVTYTGSALLRLLD---MLVSDALTVTLHLSWSAPVSLNKLAAEMVLAG
MMAR_3156|M.marinum_M               LAVTYAGLALLRLLD---MLVRAAPTLTLHLSWPAPAALKDREDDLT-AG
MAB_2050|M.abscessus_ATCC_1997      LAVTYGGLALLRLLD---MLAGAVPNIELHLSHSAPESW--VLHDEVLAG
MUL_4350|M.ulcerans_Agy99           IPCPHTLELALGVSLGVFRLLMGADYTPLAVHLPHDPLTPPTTYVRYFEC
                                    :         :                 :                     

Mb1430|M.bovis_AF2122/97            DVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGI
Rv1395|M.tuberculosis_H37Rv         DVAFGRAHNRVHFPRAMFDEPLPQADRHTLEMCIAQCDVLMQRNERRRGI
TH_3718|M.thermoresistible__bu      DVSYGADRNAITFPTALLDRPLAAANPAVAAQCIAQCDELLARHQDEPTV
Mflv_4594|M.gilvum_PYR-GCK          RLFFDAPMSYLHVPVNALNEVCRFSDPLAYRLAVAELRRTLDEQSGATSF
MMAR_3156|M.marinum_M               RLFFDAPMSFLHVPADTLNEVCRFSDPVAYRLAIVDLQRTLDQRSETTSF
MAB_2050|M.abscessus_ATCC_1997      RIFFDAPSSFVHVPAATLEEVCRFSDPVAYRIAVTDLQRTLDQRR-DTSV
MUL_4350|M.ulcerans_Agy99           TPHFAERRSGFTVRSTDLVRPLHRDELAHRAVVDYLSSITPLGAGIVESV
                                       :    . . .    : .     :                       .

Mb1430|M.bovis_AF2122/97            TALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEA
Rv1395|M.tuberculosis_H37Rv         TALVRSKLFRDSGLFPTFTDVAGELDMHPRTLRRRLAEEGTSFRALLGEA
TH_3718|M.thermoresistible__bu      ASRVRRRLARDPGAVPLMRTLATEMGFTERTLRRRLAREGTGYRSLIDEV
Mflv_4594|M.gilvum_PYR-GCK          SKKVRRLLDEDPGQR-SCQRVADELSVSTSTLKRRLAEEGTTFRELRQSC
MMAR_3156|M.marinum_M               SEKVRRLLQKEPGRR-SKHWFAHELSMSTSTLKRRLSEEETTFRELRQAF
MAB_2050|M.abscessus_ATCC_1997      SEKVRDLLEKDPGKT-NISRTAGELSISPSTLKRRLREEGTTFRELRQSF
MUL_4350|M.ulcerans_Agy99           RTMARQLLPTG---ATTLEVVAAQFHLHPKTLQRRLADESTTFAALIDEV
                                       .*  *             * :: .   **:***  * * :  *    

Mb1430|M.bovis_AF2122/97            RSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
Rv1395|M.tuberculosis_H37Rv         RSTVAVDLLRNVGLTVQQVSTRLGYTEVSTFSHAFKRWYGVAPSEYSRRG
TH_3718|M.thermoresistible__bu      RGARAADLLS-GGATVKQVAQQLGYSEPAAFHHAFVRWHALPPARFRRAD
Mflv_4594|M.gilvum_PYR-GCK          LRESAMMLLITRSMSASQIATELGYGDLANFSHAFKRWTGRSPSEYRRSQ
MMAR_3156|M.marinum_M               LRERAMLQLLDRSLSVSEIATDLGYSDLANFSHAFKRWTGRSPSEFRLSP
MAB_2050|M.abscessus_ATCC_1997      LQERAILRILDRSVSVSEIAAELGYADLTNFTHAFKRWTGRSPRHFRKTR
MUL_4350|M.ulcerans_Agy99           RKETADRYLRTTAMSLSHLARELGYAEQSVLTRSCKRWFGIGPAAYRAKT
                                        *   :   . : ..::  *** : : : ::  ** .  *  :    

Mb1430|M.bovis_AF2122/97            ---------
Rv1395|M.tuberculosis_H37Rv         ---------
TH_3718|M.thermoresistible__bu      VR-------
Mflv_4594|M.gilvum_PYR-GCK          R--------
MMAR_3156|M.marinum_M               H--------
MAB_2050|M.abscessus_ATCC_1997      D--------
MUL_4350|M.ulcerans_Agy99           RVRATPRRR