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SVSSPSLWSAGRYDAVGQRIAPIAEQVVDALDRRQPLRGAAVVDLACGTGSAALAAAARGAQVTGVDLTP ELIAIAAGREGADAVTWRTADASDTGLPAGAFDAAVSNMGIIFVDPDRQVAEIARLLKPAGRLAFSAWAR DADNPFFDPVVAVLGPPPATGFSPDQWGDTDTLTTRLAPFFDDIDVQRARHRWEFESMAAALHFLRSESP MHVATFRRAAPAQQDRLAAEFEIALRRHLEPSGAVAFTAPYVVVSATLRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1774 | - | - | 100% (261) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_2287 | - | 6e-19 | 32.82% (195) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_1928 | - | 1e-17 | 30.86% (269) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1438c | - | 3e-18 | 30.53% (190) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_4692 | - | 1e-106 | 74.03% (258) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1403c | - | 3e-18 | 30.53% (190) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 3e-15 | 30.97% (155) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_1977 | - | 2e-10 | 29.37% (143) | putative methyltransferase |
| M. marinum M | MMAR_1627 | - | 5e-16 | 28.41% (264) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 5e-16 | 32.30% (161) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_1893 | - | 6e-83 | 60.08% (263) | UbiE/COQ5 methyltransferase |
| M. thermoresistible (build 8) | TH_2937 | - | 1e-98 | 69.44% (252) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_3409 | - | 9e-16 | 27.65% (264) | methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1438c|M.bovis_AF2122/97 -MTVYTPTSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTSG---
Rv1403c|M.tuberculosis_H37Rv -MTVYTPTSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTSG---
MLBr_00551|M.leprae_Br4923 -MNLYTPIHEDQSLAAIHRAMWALGDYALMAEEVMAPLGPILVTATG---
MAV_3373|M.avium_104 -MTLDT-TTADASVAARHRTVWALGDYALMAEEVMAPLGPTLVEAAG---
MMAR_1627|M.marinum_M MTTLARTEPTDRGYESKHRALWALGDYPAVATDLVSPLGPILLEATR---
MUL_3409|M.ulcerans_Agy99 MTTLARTEPTDRGYESKHRALWALGDYPAVATDLVSPLGPILLEATR---
Mvan_1774|M.vanbaalenii_PYR-1 -------------MSVSSPSLWSAGRYDAVGQR-IAPIAEQVVDALD---
Mflv_4692|M.gilvum_PYR-GCK ---------------MTSSTFWSAGRYDAVGDR-IAPIAREVVDAAD---
TH_2937|M.thermoresistible__bu ---------------VTTN--WAAGRYEAVGER-IAPIADEVLDAAA---
MSMEG_1893|M.smegmatis_MC2_155 -------------MPQPKPTNWAAGRYQAVAER-IAPIAEEVVVAAGRVG
MAB_1977|M.abscessus_ATCC_1997 -MDPAEHARHTRDVYDRLAPVWSATTDDGPFNGLLERPALRSLIPRP---
*: : . : .
Mb1438c|M.bovis_AF2122/97 ----IRRGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAA
Rv1403c|M.tuberculosis_H37Rv ----IRRGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAA
MLBr_00551|M.leprae_Br4923 ----IRPGMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARAT
MAV_3373|M.avium_104 ----IGPGVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRAA
MMAR_1627|M.marinum_M ----ISAGDRVLDVAAGSGNVAIPAALAGADVIASDLCPNLLECGRGLAA
MUL_3409|M.ulcerans_Agy99 ----ISAGDRVLDVAAGSGNVAIPAALAGADVIASDLCPNLLECGRGLAA
Mvan_1774|M.vanbaalenii_PYR-1 -RRQPLRGAAVVDLACGTGSAALAAAARGAQVTGVDLTPELIAIAAGREG
Mflv_4692|M.gilvum_PYR-GCK -ARRPLRDAAVVDLACGTGSAALDAAARGARVTGVDITPELIAIAAERDG
TH_2937|M.thermoresistible__bu -RRTPLRGATLVDLACGTGSAALSATARGAAVTGVDITSELIALAAGKPG
MSMEG_1893|M.smegmatis_MC2_155 PQRGPLTGGDIVDLACGTGSAALAAAAAGADVTGVDITPELIDIAKTRPG
MAB_1977|M.abscessus_ATCC_1997 -----LAGRSVLDAGCGSGAQCAWLLGEGADVTGLDLSPAMVDQARQRCG
. ::* ..*:* ** : . *: . :: .
Mb1438c|M.bovis_AF2122/97 AAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCR
Rv1403c|M.tuberculosis_H37Rv AAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCR
MLBr_00551|M.leprae_Br4923 ELGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRRAASELVRVCR
MAV_3373|M.avium_104 GMGLTIDYREANAQALPFGDGEFDAVVSAIGVQFAPDHQRAADELVRVCR
MMAR_1627|M.marinum_M ARGASLRWVEANAQALPFDTDEFDAVVSCVGVMFAPYHQPCADELVRVCR
MUL_3409|M.ulcerans_Agy99 ARGASLRWVEANAQALPFDTDEFDAVVSCVGVMFAPYHQPCADGLVRVCR
Mvan_1774|M.vanbaalenii_PYR-1 AD--AVTWRTADASDTGLPAGAFDAAVSNMGIIFVDPDR-QVAEIARLLK
Mflv_4692|M.gilvum_PYR-GCK AA--AVRWRTGDASDTGLPATSFDAAVSNMGIIFVEPAR-QVAEVVRLLK
TH_2937|M.thermoresistible__bu GS--TVTWVTADAADTGLKTASFDVAVSNMGIIFVPPDR-QVAELARLLK
MSMEG_1893|M.smegmatis_MC2_155 GD--QVTWVAADATRTGLPDGGFDAAVSNMGIIFVEPTG-LVAEVARLLR
MAB_1977|M.abscessus_ATCC_1997 SA--AKLMVADLADDLPLEPRSFDGVTCSLALHYLRDWQVPLASFARILR
* : ** . . :.: : ..*: :
Mb1438c|M.bovis_AF2122/97 RGGKISTLNWTPEG---FYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVS
Rv1403c|M.tuberculosis_H37Rv RGGKISTLNWTPEG---FYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVS
MLBr_00551|M.leprae_Br4923 PNGTIGVISWTQEG---FFGRMLATIRPYRPSLSAALPPAALWGREAYIR
MAV_3373|M.avium_104 PGGRIGLISWTPEG---FFGRMLATIRPYRPSLSHPVPPAALWGRPGYVR
MMAR_1627|M.marinum_M PGGVIGLISWTPGG---FIGEMFTTMKPYLAPPLPGAQPAPLWGTEGHVR
MUL_3409|M.ulcerans_Agy99 PGGVIGLISWTPGG---FIGEMFTTMKPYLAPPLPGAQPAPLWGTEGHVR
Mvan_1774|M.vanbaalenii_PYR-1 PAGRLAFSAWARDA----DNPFFDPVVAVLGPPPATGFSPDQWGDTDTLT
Mflv_4692|M.gilvum_PYR-GCK PGGVFAFSSWVRSV----SNPLFDPVLAVLGPPATSTFSPDQWGDEAVLT
TH_2937|M.thermoresistible__bu PGGVLSFSAWIRTD----ENPFSDPVAEVLGPPPAG-FSPDQWGDAETLT
MSMEG_1893|M.smegmatis_MC2_155 PGGVFAFSAWVRDDRDGAENPFFAPIVEVLGPPSAAAFTPDQWGDRDVVA
MAB_1977|M.abscessus_ATCC_1997 PGG------WVVIS---LDHPFGAPLPDQRGGYFQHQLVSDTWNKADVEV
* * : .: *.
Mb1438c|M.bovis_AF2122/97 GLFRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSP
Rv1403c|M.tuberculosis_H37Rv GLFRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSP
MLBr_00551|M.leprae_Br4923 GLLDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYTNIGDNS
MAV_3373|M.avium_104 ALLGERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIGHNR
MMAR_1627|M.marinum_M ELFADRVTDFAVRRGALLVDEFADGASFRDYFKANYGPTIAAYRAIAAEP
MUL_3409|M.ulcerans_Agy99 ELFADRVTDFAVRRGTLLVDEFADGASFRDYFKANYGPTIAAYRAIAAEP
Mvan_1774|M.vanbaalenii_PYR-1 TRLAPFFDDIDVQRA-RHRWEFESMAAALHFLRSESPMHVATFRRAAPAQ
Mflv_4692|M.gilvum_PYR-GCK ERLGSQFDGVDVRRG-DHRWEFESMPAAMRFLTSESPMHVETFRRAETSQ
TH_2937|M.thermoresistible__bu ERLTPHFDAIDLIRG-LHPWEFDSPATALHFLRTESPVHVEIFRRAGPAR
MSMEG_1893|M.smegmatis_MC2_155 QRLAAHFGDITVETS-DLTWNFASLAAAMEFLEFESPAHVSLFQSLDTPV
MAB_1977|M.abscessus_ATCC_1997 T------QHFWRRPLGQVADAFADAGLLIERIS-EPRPSAEAIRRFPAEL
. * :
Mb1438c|M.bovis_AF2122/97 ECVATLDAEITELCREYLCDG-VMQWEYLIFTARKC--
Rv1403c|M.tuberculosis_H37Rv ECVATLDAEITELCREYLCDG-VMQWEYLIFTARKC--
MLBr_00551|M.leprae_Br4923 VLAAELDAQLTELAQKYLTNS-TMGWEYLLLTAQKH--
MAV_3373|M.avium_104 VLAAELDAQLVELAAQHLSDG-TMGWEYLLVTAEKRSG
MMAR_1627|M.marinum_M DRVAALDAELAALGDRYLAGSSAMEWEYLLVTARKR--
MUL_3409|M.ulcerans_Agy99 DRVAALDAELAALGDRYLAGSSAMEWEYLLVTARKR--
Mvan_1774|M.vanbaalenii_PYR-1 QDRLAAEFEIALRRHLEPSGAVAFTAPYVVVSATLRA-
Mflv_4692|M.gilvum_PYR-GCK RARLAAEFEDALRPHLEPSGSVAFLSPYVVVTATLRG-
TH_2937|M.thermoresistible__bu RERLAAAFRSALRPHAGPAGTVGFTAPYVIVTARRRG-
MSMEG_1893|M.smegmatis_MC2_155 RDRLRSVFEAALRRHVDTTGTVAFASPYLVTTALRR--
MAB_1977|M.abscessus_ATCC_1997 RNVVDSPSFIVYRLRYWGAPA-----------------
.