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LSRGSNHGNSSILVGRRRCGHRECCGGSPGDRTHHVHPGRGRRVCDGDPAQRGTGRQFAVVGVGTARHRR ADGGSAADQCGLRRVRRSRSGRVRRCADLRPNRTESCCRRRIRVPRRTGGGVPRIGAGRGAGLSGRGGER LGVRRRLRAVRSGRSHLRRRPAGCGGVCLAARQRRGVRRGFRPVATDRRVLRRRPARCGGVRVAACQRRG FRRGLLPVGGDRRVLRRWTRCGGRDRLTGAQRCGVRRELVPLGCDRVVLRRLSRRRHHRHLRRHPVRVRR HHRNGRPGRRAGRRGGRGGGRRGPGGAGGGGAGRHGGSDGARSGGCGRHVRPRGGRRDRAGRGFPGLRRR GGRGAGGDHGAGVERGHGTGGGFGAGAGRDHGGGGGFRDGRRGRDHGGGGGFRDGRRGRDHGGGGGFGVG VGRGRNLRHSGEVRHSGEVRHGGEVGQCRHLGQGRSGVGERRPALTARP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1363 | - | - | 100% (469) | LigA |
M. vanbaalenii PYR-1 | Mvan_3867 | - | 4e-16 | 36.70% (188) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_2314 | infB | 6e-15 | 38.83% (188) | translation initiation factor IF-2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 5e-19 | 39.33% (178) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_2178 | - | 3e-16 | 37.70% (191) | hypothetical protein Mflv_2178 |
M. tuberculosis H37Rv | Rv3507 | PE_PGRS53 | 5e-19 | 39.44% (180) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 5e-10 | 39.37% (127) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_3131c | - | 3e-12 | 37.27% (161) | translation initiation factor IF-2 (InfB) |
M. marinum M | MMAR_1829 | - | 3e-18 | 39.66% (174) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 4e-12 | 39.58% (144) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-13 | 34.43% (183) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 8e-11 | 34.09% (176) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4581 | - | 3e-18 | 38.59% (184) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1829|M.marinum_M ------------MSLVSVVPEWVAAAATDVAGIGSVVGAANAAAAGATTS MUL_4581|M.ulcerans_Agy99 ------------MSYVIAAPELLAGAATDLAGLGSTLQIANRAAAATITG Mb3541|M.bovis_AF2122/97 ------------MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQ Rv3507|M.tuberculosis_H37Rv ------------MSFVLVSPETVAAVATDLKRIGASLAHENASAAASTTA Mflv_2178|M.gilvum_PYR-GCK ------------MSGTAHAPGKTRLFANVTVAVG--LGGAALGAAALLAP MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASST MAB_3131c|M.abscessus_ATCC_199 ------------MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASST Mvan_1363|M.vanbaalenii_PYR-1 ------------MSRGSNHGNSSILVGRRRCGHRECCGGSPGDRTHHVHP MAV_4827|M.avium_104 ------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTG MMAR_1829|M.marinum_M ----------VAAAAGDEVSVAIAALFGGFGREYQVVCGQWAEFERRFAG MUL_4581|M.ulcerans_Agy99 ----------VPAAGADDVSAALAAVFSGHALDYQALSAQMAGVHQRFVQ Mb3541|M.bovis_AF2122/97 ----------VLAAGADEVSARIAALFGMYGLEYQAISAQVAAYHQQFVQ Rv3507|M.tuberculosis_H37Rv ----------VVSAAADEVSTAVAALFSQHAQGYQAAAAQVAAFHSRFVQ Mflv_2178|M.gilvum_PYR-GCK ----------QASAAPEEWLPAGPSSECPPPTDGCANVAAVGGVHG---- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDK MAB_3131c|M.abscessus_ATCC_199 VEAPVARRLRESFGGGDKPAPAASNGAAAEAAAP-------------PKK Mvan_1363|M.vanbaalenii_PYR-1 ---------------GRGRRVCDGDPAQRGTGRQFAVVGVGTARHRRADG MAV_4827|M.avium_104 ---------ADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQ MMAR_1829|M.marinum_M ALGAGAGAYAGAEAAAVGMLSPLGVVEQGVWGAVNGPAVALWGRPLVGDG MUL_4581|M.ulcerans_Agy99 ALTASGSSYAAAEAANT---NPLQGVEEHLLGVLNSPTQALLGRPLIRDG Mb3541|M.bovis_AF2122/97 TLRTGAASYMLAEATNVE---------QNLLNLINAPTQTLLGRPLIGDG Rv3507|M.tuberculosis_H37Rv ALTAGAGAYAFAEAANASP-------LQSAMGAVSASAQTLLSRPLIGNG Mflv_2178|M.gilvum_PYR-GCK --AQGPANLATPQTSGSP-----------------------LFRPLFGNG MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -----------------------------------------------VDG MLBr_01556|M.leprae_Br4923 AVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPG MAB_3131c|M.abscessus_ATCC_199 AGPKPGAPKPAPKKVAEPVVEAPVAP-EPPAAPAAPAAPAPKPSPAARPA Mvan_1363|M.vanbaalenii_PYR-1 GSAADQCGLRRVRRSRSG--------------------RVRRCADLRPNR MAV_4827|M.avium_104 LEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEP MMAR_1829|M.marinum_M ADGVAGT-----GQAGGAGGLLWGNGGSGGSGGVGQSGGAGGSAGLIGRG MUL_4581|M.ulcerans_Agy99 AAGAP-------GQDGGDGGLLLGNGGAGGTG------------------ Mb3541|M.bovis_AF2122/97 ANATTP------GGAGGDGGLLFGSGGNGAPGAPGQAGGAGGSAGLLGNG Rv3507|M.tuberculosis_H37Rv ANATTP------GGNGGDGGWLFGSGGNGAPGAAGQSGGNGGSAGLWGNG Mflv_2178|M.gilvum_PYR-GCK ADAPADCV--GNACNGRDGGLIWGNGGAGANG------------------ MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu D-----------GGSGGRTG-LFSKLSRGGDG------------------ MLBr_01556|M.leprae_Br4923 VPLPGQQ-----GTPAAPHPGHPGMPTGPHPGPAPKP------------- MAB_3131c|M.abscessus_ATCC_199 AAEAAAP-----APAPAPAP-RPGATPGPKPG-AP--------------- Mvan_1363|M.vanbaalenii_PYR-1 TESCCRRRIRVPRRTGGGVPRIGAGRGAGLSG------------------ MAV_4827|M.avium_104 DTATLAVVETSDGSIPDVYKQQIRAESYGDAAG----------------- MMAR_1829|M.marinum_M GAGGAGGFSGGSGAGGAGGVGGNGGWLWGAGGDGGAGGVGAVSGGVGGGA MUL_4581|M.ulcerans_Agy99 -------YSPTTGSG-------------AVGGDGGAG-------GTGG-- Mb3541|M.bovis_AF2122/97 GSGGAGGTG-APGGNG-----GNAGWLYGRGGVGGAGGIG---GGTGGAG Rv3507|M.tuberculosis_H37Rv GAGGAGGSGGAAGGNG-----GNGGWLFGAGGTGGIG-------GTGAPG Mflv_2178|M.gilvum_PYR-GCK ----------------------------GHGGNAG--------------- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAG--------QQFWVVSPIGSTLG------GVINTI TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GRAWLWGAGGAGGAGGQGVGLDGGAGGGGGQGGLVYGGGGDGGTGGVGAV MUL_4581|M.ulcerans_Agy99 ---WLYGSGGSGGIG------------------------GVGGSGTIGAP Mb3541|M.bovis_AF2122/97 GHAWLFGHGGTGGIG----------GGPGGNGGWLLGNGGHGGAGGIGGG Rv3507|M.tuberculosis_H37Rv ------AMGGTG--------------GNGGNGALLIGGGGLGGAGGMGGT Mflv_2178|M.gilvum_PYR-GCK ----------------------------------LVGNGGRGGDATTPGR MSMEG_0868|M.smegmatis_MC2_155 SGQYLIGNGINGTAD----------NPNGGTGGLLFGDGGHGYDGSAAGL TH_3810|M.thermoresistible__bu ------------------------------------GDGGLGGNGGHGGG MLBr_01556|M.leprae_Br4923 -----------------------------------GGRPPRVGNNPFSSA MAB_3131c|M.abscessus_ATCC_199 -------------------------------------RVPRVGNNPFSSA Mvan_1363|M.vanbaalenii_PYR-1 -----------------------------------RGGERLGVRRRLRAV MAV_4827|M.avium_104 -----------------------------------QLSAMVAGLEKLESL . MMAR_1829|M.marinum_M SGGVGG-------------GAGRAWLWGAGGAGGAGGQGVGLDGGAGGGG MUL_4581|M.ulcerans_Agy99 SG------------------------------------------------ Mb3541|M.bovis_AF2122/97 SGGAGGNGGWLLGNGGIGGAGGTGGGAGGTGGNAAWLLGGGGTGGAGGIG Rv3507|M.tuberculosis_H37Rv GGGTGG--------------------TGGNGGNGALLIGAGGVGGAGGIG Mflv_2178|M.gilvum_PYR-GCK SGG----------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AGGNGG---------------------------NAGLFGNGGNGGVG--- TH_3810|M.thermoresistible__bu TGIIS--------------------------------------------- MLBr_01556|M.leprae_Br4923 QSVARP-------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 QPAERP-------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 RSGRSH-------------------------------------------- MAV_4827|M.avium_104 PGGLLLVG------------------------------------------ MMAR_1829|M.marinum_M GQGGLVYGGGGDGGAGGVGGEVGGGGVGGTGG-AGGAAG----LIGRGGD MUL_4581|M.ulcerans_Agy99 --------------------------HGGSCG-LGGGTG----LFGQGGA Mb3541|M.bovis_AF2122/97 GGNGGHGGNGGWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGG Rv3507|M.tuberculosis_H37Rv GQGTGAGG---------------AAGAGGTGG-NGGAGG----LFMNGGD Mflv_2178|M.gilvum_PYR-GCK --------------------------HGGNGGRLWGNGG-------DGGN MSMEG_0868|M.smegmatis_MC2_155 --------------------------WAGLDGGNGGSGG---LLMGIGGA TH_3810|M.thermoresistible__bu -------------------------------------------LLSLAGN MLBr_01556|M.leprae_Br4923 -----------------------------IPRPPAPRP------SASPSS MAB_3131c|M.abscessus_ATCC_199 -----------------------------APRPQAPRPGAPRPGGASPSN Mvan_1363|M.vanbaalenii_PYR-1 -----------------------------LRRRPAGCGG----VCLAARQ MAV_4827|M.avium_104 ----------------------SGVDVAPLKQVLQTTTFLDVSVAEEPET MMAR_1829|M.marinum_M GGGGGAG-DGGSTGGAGQTGGDGGRAGDG------------GVGGRG--- MUL_4581|M.ulcerans_Agy99 GGNGGQG-GGE---NFASTAGAGGPAG---------------TGGHG--- Mb3541|M.bovis_AF2122/97 GGNGGAGSTGTAGGGSGGTGGDGGTGGRGGLLMGAGAGGHGGTGGAGGAG Rv3507|M.tuberculosis_H37Rv GGAGGQGGDGAAGDAAASAGGTGGKGGQG---------GDGGTGGAGGAG Mflv_2178|M.gilvum_PYR-GCK GAPGVLGPAGTAPIPPSSLPAATGTRGDS------------PPYGYG--- MSMEG_0868|M.smegmatis_MC2_155 GGAGGVGADGTSAHVDGGTGGTGGTGGGTG-----------GTGGIGGTG TH_3810|M.thermoresistible__bu GGNGGNG--YRTTDNNALDGGHGGNGGN--------------VGFFS--- MLBr_01556|M.leprae_Br4923 MSPRPGGAVGGGGPRPPRTG-VPRPGGGRP------------GAPVG--- MAB_3131c|M.abscessus_ATCC_199 MPPRP--SPGSMGPRPPRPGGGPRPGGGPR------------PGGAG--- Mvan_1363|M.vanbaalenii_PYR-1 RRGVRRGFRPVATDRRVLRRRPARCGGVR--------------------- MAV_4827|M.avium_104 ALARGAALAAANAPLFASSTAALAYAQDPG------------TGAVDQYS MMAR_1829|M.marinum_M ----------------------GWLAGAGGDGGAGGVGGVGGAGGGGADG MUL_4581|M.ulcerans_Agy99 ----------------------GWLYGNGGAGGIGGAGGVVGSSEGGVD- Mb3541|M.bovis_AF2122/97 VDGGGAGGAGGAGGNGGAGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDG Rv3507|M.tuberculosis_H37Rv P----------------------VLFGHGGAGGMGGQGGTGGMGGAGGDG Mflv_2178|M.gilvum_PYR-GCK ----------------------NLVGGDGGTGADGGRYAFGANWSLDLP- MSMEG_0868|M.smegmatis_MC2_155 G------------------GLFGLLGHSGSTGAAGAAGNGGDGGNGGFGY TH_3810|M.thermoresistible__bu ------------------------LFNLGGAGGWGGSGVDGVDVVGGNP- MLBr_01556|M.leprae_Br4923 ------------------------GRSDAGGGNYRGGGVG-ALPGGGS-- MAB_3131c|M.abscessus_ATCC_199 ------------------------RPGGGGGGNYRGGGTGTGAPAGGPP- Mvan_1363|M.vanbaalenii_PYR-1 ------------------------VAACQRRGFRRGLLPVGGDRRVLRRW MAV_4827|M.avium_104 LP------------------DYLYVPVDPEPGDDELAYSAVGEEDAESPT * MMAR_1829|M.marinum_M LVLGGDGGDGGDGGTGG---AGGSGGAGGAGGLISLFGGQGAGGAGGAGG MUL_4581|M.ulcerans_Agy99 ------------GGVGG---SGGSGGATG------LLGNSGAGGTGGQGG Mb3541|M.bovis_AF2122/97 TMAGLGG-TGGSGGTGGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGG Rv3507|M.tuberculosis_H37Rv TTVIAAG-TGGEGGTGG---AAGAGGAAGARGALTSGGLAGGVGAGGTGG Mflv_2178|M.gilvum_PYR-GCK --------------VGG---AGGAGGWANSIDGSATGGNGGDGGNGAFGG MSMEG_0868|M.smegmatis_MC2_155 VLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIG TH_3810|M.thermoresistible__bu --------------DGG--TPGAHGESHTPGVYTDRQGEDGEDGTG--TG MLBr_01556|M.leprae_Br4923 ---------------GGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAP MAB_3131c|M.abscessus_ATCC_199 ------------GAGGGFRGRPGGG--GGGGRPGQRGGAAGAFGRPGGAP Mvan_1363|M.vanbaalenii_PYR-1 TR------------------CGGRDRLTGAQRCGVRRELVPLGCDRVVLR MAV_4827|M.avium_104 VVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGT . . MMAR_1829|M.marinum_M AGGLAGDGG-VGAAGTFAGGGSG-TGGAGGDGGTPGVGG-AGGAGGAGSV MUL_4581|M.ulcerans_Agy99 GGGRGFDGS-LG-----AGGAEG-TGAVGGSG------------------ Mb3541|M.bovis_AF2122/97 TGGNGGAGS-AGADAPAGSGAMGSTGFAGGAGGDGGNGGGSGASQGNGGN Rv3507|M.tuberculosis_H37Rv TGGTGGNG--ADAAAVVGFGANGDPGFAGGKGGNGGIGG----AAVTGGV Mflv_2178|M.gilvum_PYR-GCK RGGNGGAG---GSAYGRGGITTGGNGGAGGHGSTG--------------- MSMEG_0868|M.smegmatis_MC2_155 ANGGTVDG--HAIGGNGGNGGNGSTTAAGGNGGTGGTGR---------VI TH_3810|M.thermoresistible__bu IGGRGGNG----------GSSSGTHPMAEDGEHVKALDG----------- MLBr_01556|M.leprae_Br4923 RRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLAR----------- MAB_3131c|M.abscessus_ATCC_199 KRGRKSKRAKRAEYENMQAPVVGGVRLPHGNGEVIRLAR----------- Mvan_1363|M.vanbaalenii_PYR-1 RLSRRRHHR----------HLRRHPVRVRRHHRNGRPGR----------- MAV_4827|M.avium_104 VALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAP-------- MMAR_1829|M.marinum_M AGAHGSEGARPLSGDGGSGGRGADSTVAGGIAGDGGVGGNGGVFG----- MUL_4581|M.ulcerans_Agy99 ----------------------------GWLVGDGGTGGDG--------- Mb3541|M.bovis_AF2122/97 GGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQ Rv3507|M.tuberculosis_H37Rv AGDGGTGGKGGTG-------------------GAGGAGNDAGS------- Mflv_2178|M.gilvum_PYR-GCK --------------------------------AAGGRGGD---------- MSMEG_0868|M.smegmatis_MC2_155 AEGTGSTAEG---------------------TATGGDGGHSTGTG----- TH_3810|M.thermoresistible__bu --------------------------------RPGLDGGN---------- MLBr_01556|M.leprae_Br4923 --------------------------------GASLSDFAEKIDAN---- MAB_3131c|M.abscessus_ATCC_199 --------------------------------GASLSDFAEKIDAN---- Mvan_1363|M.vanbaalenii_PYR-1 --------------------------------RAGRRGGRG--------- MAV_4827|M.avium_104 -------------------------KPLSPPVAAPLPAAPPPAAPP---- MMAR_1829|M.marinum_M ----------NGGSGGAGGTGVAGQRGVSADTAGGSGTAGEDGGVGGDGG MUL_4581|M.ulcerans_Agy99 ----------------------------------------------GQGG Mb3541|M.bovis_AF2122/97 GADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGG Rv3507|M.tuberculosis_H37Rv -----------------------------TGNPGGKGGDGGIGGAGGAGG Mflv_2178|M.gilvum_PYR-GCK ----------------------------------------------GASA MSMEG_0868|M.smegmatis_MC2_155 --------------------------------IGGNGGIGSVYAYGNNGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------------------------------------------PAALV MAB_3131c|M.abscessus_ATCC_199 ---------------------------------------------PASLV Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------LPEAPPIPAAPPVVPVPVVVP MMAR_1829|M.marinum_M AGGLG-GALAGHGGDGGAGGIGGAGGDGGSGAAGAAGDRGIIAHLDGGRG MUL_4581|M.ulcerans_Agy99 GGHLG-GAFAGGGGDGGAGAVGGTGG------------------------ Mb3541|M.bovis_AF2122/97 AAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTG Rv3507|M.tuberculosis_H37Rv AAGTGNGGHAGNTGDGGDGGTGGNGGNGTGGVN----------------- Mflv_2178|M.gilvum_PYR-GCK SGGYAVGGNGGDGGRGGAGATGGTGGTG---------------------- MSMEG_0868|M.smegmatis_MC2_155 VSGTATGGRGGDGIDGGTGGAGGMGEIYSGADG----------------- TH_3810|M.thermoresistible__bu ------GSHGGNGGHGGRGGFLGIGGSG---------------------- MLBr_01556|M.leprae_Br4923 QALFNLGEMVTATQSVGDETLELLGSEMN--------------------- MAB_3131c|M.abscessus_ATCC_199 QALFNLGEMVTATQSVGDETLELLGGEMN--------------------- Mvan_1363|M.vanbaalenii_PYR-1 ------GGRRGPGGAGGGGAGRHGGSDG---------------------- MAV_4827|M.avium_104 PVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQP------------------ . MMAR_1829|M.marinum_M GDGGSGADGGAG---------GSGGNGGAGGQAQAAGYADGVRGAGGSGG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGG Rv3507|M.tuberculosis_H37Rv -----------------------------------GADN--TLNPDTPGG Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------------EATGISAGGD TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------------VQP MMAR_1829|M.marinum_M AGGAGGLAGAGGAGGDAYTTGGGAGGDGGHGGDTGAGGAGGSGGVGSSTG MUL_4581|M.ulcerans_Agy99 -----WLLGDGGAGGD---------------------------------- Mb3541|M.bovis_AF2122/97 AGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSL Rv3507|M.tuberculosis_H37Rv AGEPGGAGGAGGAGGAAG-------------------------------- Mflv_2178|M.gilvum_PYR-GCK -----GAGGDGGRGGLLG-------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGSATGADSLGGRGGTSWVQAG---------------------------- TH_3810|M.thermoresistible__bu -----GWGGHGGNGGDTD-------------------------------- MLBr_01556|M.leprae_Br4923 --YNVQVVSPEDEDRELLEP------------------------------ MAB_3131c|M.abscessus_ATCC_199 --YVVQVVSPEDEDRELLES------------------------------ Mvan_1363|M.vanbaalenii_PYR-1 -------ARSGGCGRHVR-------------------------------- MAV_4827|M.avium_104 PVRVPQPPSPPQVGGTVPQSPP---------------------------- . MMAR_1829|M.marinum_M LTGLSGHSPTSGGDGGDGGAGGRGAIDIAGGTGGAGGDGGTYGDGGDGGA MUL_4581|M.ulcerans_Agy99 -----------GGDGGDGGAAS---------------------------- Mb3541|M.bovis_AF2122/97 DPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGN Rv3507|M.tuberculosis_H37Rv ---------GPGGTGGTGGNGGNG---------GNGGNGGNGGNGGNGGN Mflv_2178|M.gilvum_PYR-GCK ------------GHGGKGGNAGLG-------------------------- MSMEG_0868|M.smegmatis_MC2_155 ------YGPTTGGKASGTAKAGHG---------GKASDGGKGGNGGDALV TH_3810|M.thermoresistible__bu ------------ADGGNGGDGGNG-------------------------- MLBr_01556|M.leprae_Br4923 ------FDLTYGEDQGDEDELQVR-------------------------- MAB_3131c|M.abscessus_ATCC_199 ------FDLTYGEDEGGEEDLRTR-------------------------- Mvan_1363|M.vanbaalenii_PYR-1 ------------PRGGRRDRAGRG-------------------------- MAV_4827|M.avium_104 ------QHQTPPGEGTPPKPDGPG-------------------------- MMAR_1829|M.marinum_M GGDGVTGSQGLTATTPGGSGTNGGAGSAGGAGGSGGLGGTLAGHGGDGGA MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTG--TGGQQGNGGNGGN Rv3507|M.tuberculosis_H37Rv AGNNSTNAPVGGEGGAGGDGGAG---GAGGAANGG--TAGSQGTGGVGGD Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTN-------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GGAGGDGGFGGSGATGSSGDQGSAANPNGGRGGDGGSGADGGAGGTGGDG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGKGGTGGDGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDG Rv3507|M.tuberculosis_H37Rv GGAGGNGG--------------GGKAGTG-NSGNFGVDGEAGFS-----G Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GAGGQAQAAGYADGTRGAGGNGGAGGSGGLAGDGGRGGDGAVGFGGAGGD MUL_4581|M.ulcerans_Agy99 ----------------------------GFAGDGGQGGQGAVG------- Mb3541|M.bovis_AF2122/97 GKGGNG-GIG-AAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGTAGA Rv3507|M.tuberculosis_H37Rv GAGGNG-GVGGAAGANG--GTGGSGGNGGDGGAGGIGGAGGNGIPGTG-T Mflv_2178|M.gilvum_PYR-GCK -------------------------GNGGTGGTGGVGGDGGVG------- MSMEG_0868|M.smegmatis_MC2_155 -----------IAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP TH_3810|M.thermoresistible__bu ----------------------------GSAGRGGTGG------------ MLBr_01556|M.leprae_Br4923 ---------------------PPVVTVMGHVDHGKTRLLDTIRKANVR-- MAB_3131c|M.abscessus_ATCC_199 ---------------------PPVVTVMGHVDHGKTRLLDTIRKANVR-- Mvan_1363|M.vanbaalenii_PYR-1 --------------------------FPGLRRRGGRGAGGDHG------- MAV_4827|M.avium_104 ------------------------NYGGGHVPTPGAGGSGGSGGGHVP-- * MMAR_1829|M.marinum_M GGHGGNTGAGGVGGKGGVGSTTGLTGLGGHSPTNGGNGGAGGDGGKGAVD MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGAGGNGGKGGDGGAGVTSS------------------------------ Rv3507|M.tuberculosis_H37Rv EPAGGTGAKGGDGGDGGAGG------------------------------ Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGG---------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M IAGGVGGAGGNGGAYGNGGAGGDGGDGV------------NGTRGLTAIA MUL_4581|M.ulcerans_Agy99 --GASGWLLGNGGAGGDGGAGGEGGD-----------------------S Mb3541|M.bovis_AF2122/97 TAGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGGDGGDGAAGAVGIS Rv3507|M.tuberculosis_H37Rv AGGNAGGAGGQGGNAGQGGAGGAGGN---------------------AVI Mflv_2178|M.gilvum_PYR-GCK --GGILTATGVVGAGGSGGAGGTGGR------------------------ MSMEG_0868|M.smegmatis_MC2_155 -NGGDGGFNGTGGATGGRGGDGAGAS----------------------VW TH_3810|M.thermoresistible__bu ----LRGVFGINGGNGRAGLGGRGXX-----------------------X MLBr_01556|M.leprae_Br4923 -EAEAGGITQHIGAYQVGVDLDGSER---------------------LIT MAB_3131c|M.abscessus_ATCC_199 -EGEAGGITQHIGAYQVAVEHDGTER---------------------PIT Mvan_1363|M.vanbaalenii_PYR-1 --AGVERGHGTGGGFGAGAGRDHGGG------------------------ MAV_4827|M.avium_104 -TPGAGGSGGSGGGHVPTPGTGGPGG-----------------------T * . MMAR_1829|M.marinum_M PGGSGTDGGAGSAGGAGGYGGNGGALAGDGGDGGDGGNGGSGGDGGS--- MUL_4581|M.ulcerans_Agy99 SGGAASAGGDGGAGGAGGAGANGGLLIGHGGAGG----GGTGGNGHG--- Mb3541|M.bovis_AF2122/97 GATGAGDGGHGGTGGAGGNGGTG----GAGGSGIDGVGGGTGGTGGNGGN Rv3507|M.tuberculosis_H37Rv PGDGVGKAPHGDAGGSGGDGGKG----GQGGS------GGTGGSG----- Mflv_2178|M.gilvum_PYR-GCK -GGDGGDGGQAGRGGAGGLAGRS----GADGEAG---DAGTGGRGG---- MSMEG_0868|M.smegmatis_MC2_155 KANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGN----GGAGGAGG---- TH_3810|M.thermoresistible__bu XGGGVGAAVRSGNGVFSGGGGTP-----SAGFGVPTTIQFPAGSCT---- MLBr_01556|M.leprae_Br4923 FIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADV MAB_3131c|M.abscessus_ATCC_199 FIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADV Mvan_1363|M.vanbaalenii_PYR-1 --GGFRDGRRGRDHGGGGGFRDGRRGRDHGGGGGFGVGVGRGRNLR---- MAV_4827|M.avium_104 GGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTPGAG--- .. MMAR_1829|M.marinum_M GANGGAGTNGTTTGIPDGGRGGDGGHGGHGGDGGAGGHGGVAGKAQAAGY MUL_4581|M.ulcerans_Agy99 RPIG---------------------------------------------- Mb3541|M.bovis_AF2122/97 GAIGGAGGDAGGSG-NSGGNGGTGGKGGNAGAGGAAGSNGGTVGANGTGG Rv3507|M.tuberculosis_H37Rv APIG-------------GGAGGTGGSGGHAGKGGAGG-----IGAQGTT- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 VSEG---------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 PIVVA--------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 PIVVA--------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M TDGTHGAGGVGGNGGAGGLAGDGGRGGNGAATASGNGGDGGNGGDPGVGG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 DGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSGGAGGDGIGGVGGG Rv3507|M.tuberculosis_H37Rv ---------ITVPGNGGNAGDGGNGGNAGAGGNGGSGDFGGNTTSGASGS Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M AGGKGGIGETIGLSGLGGYNPT--SGGNGGDGGDGGSGSDGDFNHLAGSD MUL_4581|M.ulcerans_Agy99 ------------------------SGGAGGDGGDGGTG------------ Mb3541|M.bovis_AF2122/97 KGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGAGGAAGAGGAG Rv3507|M.tuberculosis_H37Rv -GGNGGNAGTAGSGGAGGTGGTGLSGGNGGNGGNGGNGGDG--------- Mflv_2178|M.gilvum_PYR-GCK ------------------------AGGSGGKGGISGTG------------ MSMEG_0868|M.smegmatis_MC2_155 ------------------------EGGTGGHGGDGGRGGDG--------- TH_3810|M.thermoresistible__bu ------------------------SRAVSREGIMPSSR------------ MLBr_01556|M.leprae_Br4923 ------------------------VNKIDKEGADPAKIRGQLTEYG---- MAB_3131c|M.abscessus_ATCC_199 ------------------------VNKIDKEGADPAKIRAQLTEYN---- Mvan_1363|M.vanbaalenii_PYR-1 ------------------------HSGEVRHSGEVRHG------------ MAV_4827|M.avium_104 ----------------------TPGGGLGGFGGGHAPAPGG--------- . MMAR_1829|M.marinum_M GGNGGHGGSGGAFGNGGNGGDGGTGGDGSRAFQPEIAGGAAGHGGAGGAG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGANGTAGNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGAGGTGGAGGD Rv3507|M.tuberculosis_H37Rv -------GNGAHGTVGAQFVPATSLPTPNGGAGGNGGTGSNGGAPGPAG- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GDGGYLAGNGGTGGTGGAGGAGG---------------TGAAGEPQFENG MUL_4581|M.ulcerans_Agy99 ---GWLYGNGGHGGTGATGGSG---------------------------- Mb3541|M.bovis_AF2122/97 GVGGAGGGNGGHGGDAGDGGNGANGNNRSSGSFLAAGGTGGAAGDGGQGG Rv3507|M.tuberculosis_H37Rv APGPTTGGNAGSQGIGGDGGN----------------------------- Mflv_2178|M.gilvum_PYR-GCK -----TPGGAGQSGQSATGRS----------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----ALGGNGGTGGVGLGNGGK---------------------------- TH_3810|M.thermoresistible__bu ----AASARAGAACASSTSRSR---------------------------- MLBr_01556|M.leprae_Br4923 ----LVAEDFGGDTMFIDISAK---------------------------- MAB_3131c|M.abscessus_ATCC_199 ----LVAEDFGGDTMFVDISAR---------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------GEVGQCRHLGQGRSG---------------------------- MAV_4827|M.avium_104 ----GLGGGGGHAPAPGGGLGG---------------------------- * MMAR_1829|M.marinum_M QNGGAGGIGRAGGAGGDGGNGGHAHAAGFQNGAGGAGGDGGQGGTGGGGG MUL_4581|M.ulcerans_Agy99 ---------RHSGASGDGGDGGDAQAIG---------------------- Mb3541|M.bovis_AF2122/97 QGGAGGGAGGQGGAGGAGGTGGNGGNITGGT-------AGTAGAAGNGGA Rv3507|M.tuberculosis_H37Rv -----------GGDGGKGGDGADAVNVVFMP-------TEPQAATGTAGS Mflv_2178|M.gilvum_PYR-GCK -----------GGAGGEGGAG----------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----------GGNGGNGGNGGTYVDPSHTG------------------- TH_3810|M.thermoresistible__bu -----------RSFCCSRA------------------------------- MLBr_01556|M.leprae_Br4923 -----------VGTNIEALLEAVLLTADAALD------------------ MAB_3131c|M.abscessus_ATCC_199 -----------QGTNIEQLLEAVLLTADAALD------------------ Mvan_1363|M.vanbaalenii_PYR-1 -----------VGERRPALTARP--------------------------- MAV_4827|M.avium_104 ----------FGGGHSGGGLGGLGGGHK---------------------- . MMAR_1829|M.marinum_M FGGDGKAGYNQRAGGDGGAGGDGGFGGTGGTGGLNGDGTTRATSGANGIR MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVGGGTVPAGSGGQG Rv3507|M.tuberculosis_H37Rv AG-----------------DPTGGNGGPGTPGSPMVAPPPPTPITQVQQG Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ------------------------------------------------AG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------------------------------LR MAB_3131c|M.abscessus_ATCC_199 ------------------------------------------------LR Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GDGGSGGTGG----------------------NGLGGRTENGDGGHGGKG MUL_4581|M.ulcerans_Agy99 -DGGAGGSGG----------------------LLFG-----APGAHG--- Mb3541|M.bovis_AF2122/97 GNAGGGGAGGQGGADGGSGGDGGDAGTGGNGGNGGNRNSGNGTGGAGGNG Rv3507|M.tuberculosis_H37Rv GDGGAGGTG------------------------STNANDGTATGGKGGEG Mflv_2178|M.gilvum_PYR-GCK ---GAGGTDD---------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGAGRIR--------------------VNNGTATGTATGGNGGNG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ANSGMEAQG--------------------------VAIEAHLDRGRGPVA MAB_3131c|M.abscessus_ATCC_199 ANPDMEAQG--------------------------VAIEAHLDRGRGPVA Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GVGGYGSVGGVGGS-GGHGGNGGQSGTPRFGGHGGDGGAGGAGVVTGGTG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGGANGGAGGAGGSGGGTGGNGGAGGDAGDAGNGGNGNGTGNGGN-GGNG Rv3507|M.tuberculosis_H37Rv G---------VGSILGGPGGNGGTGGNASATGTNGVAN-AGNGGK-GGDG Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 G---------NGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFT MAB_3131c|M.abscessus_ATCC_199 TVLIQRGTLRVGDSIVAGDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFT Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GTGGAGGNGLDGTAKAAGGNGGNGGVGGAGGVAGGAGGAGGAGGAGGNGP MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GIAGMGGNGGAGTGSGNGGNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGG Rv3507|M.tuberculosis_H37Rv GQFGAGGNGGAGGSVTDGSAGSTAGNGG-------------NGGNATNGT Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 SVPGAGDNFLVVDEDRIARQIAD--------------------------- MAB_3131c|M.abscessus_ATCC_199 SVPGAGDNLLVVDEDRIARQIAD--------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GGLFGPDGGSGGSGGNGGAGGSGGTTGTGGAGGGGGNGGNGGTGFSTNNV MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AAGTGGTGGDGGLTGTGGTGGSGGTGGDGGNGGNGGNGADNTANMTAQAG Rv3507|M.tuberculosis_H37Rv IAGQP----------AGGNGSAGGKGGDGGN------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 QGTIEANGPSAVASGIGAGG-NGGDGIDGGLGGNGGDGVVNTTANAANP- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MAB_3131c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M ASGGMGGGGGKGGGGGDGLIGGAGGGGGDGGNGAAGLTSGGNGGAGGAGG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGGA----GGDGGNGAIGG Rv3507|M.tuberculosis_H37Rv ---------------------IAAGATGTAGNGGN----GGNGNDGAVN- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----------GSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 --------------------------RRSARKRNALAARSRKRISLEDLD MAB_3131c|M.abscessus_ATCC_199 --------------------------RRSARKRNALAARSRKRISLDDLD Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M AGGAGRTTSGDGGSGGNGGTGGEGGGDILVAPVVAG----TGGAGGEGGA MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 HGPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGT Rv3507|M.tuberculosis_H37Rv --------AGTGGSGGNGGNAGGGGA-----NGGDGGAGGAGGAGGRGGK Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 SALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRG----- MAB_3131c|M.abscessus_ATCC_199 AALKETSQLNLILKGDNAGTVEALEEALLGIAIDDEVQLRVIDRG----- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GGYSNTVGGVAGNGGAGGSGGTGGTLAAHKVVYTSSGRGGVGGTGGVGGS MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGEGGEVGGAGGTGGAAGNGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDP Rv3507|M.tuberculosis_H37Rv GIDGG-------------FGGDGGNGGSNNGTG-AGGNGGNGGTGGVG-- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ATTAG------------ATGGAGGFSNIAAIHGAITDSTAISGHGGAGNG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------------------VGGITETNVNLASASDAIIIGFN------ MAB_3131c|M.abscessus_ATCC_199 ---------------------VGGVTETNVNLASASDAIIIGFN------ Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M STYGTGGVGGTGGTGGMGGAADLNNYAAAS--GAGGTGGIGGAGVTGGDG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 RVGGSGGDGGTGGSGGAAGNGGNGGNAGAGGNGNGGTGGAGGIGGTGGNG Rv3507|M.tuberculosis_H37Rv SVGAAGGDGGNGGTGGFAGFGGTAGNG-----GSGGTGGAGGDGGTGGDG Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -VRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLG MAB_3131c|M.abscessus_ATCC_199 -VRAEGKATELANREGVDIRYYSVIYQAIDEIESALKGMLKPVYEEVELG Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M GRGGTGGRSAYIGIPGTGGIGGIGGLGTAGLGGYGGDGGTGGSGHGVAGG MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GDAEPGVPPGAGGAGGAGTTGGKG--GTGGNGSGTGSGGTGGDGG--TGG Rv3507|M.tuberculosis_H37Rv G---------------NGVIAGGG--GTGGNGGASGAGGAGGTGG--FAG Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNG------GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSL MAB_3131c|M.abscessus_ATCC_199 RAEIRAMFRSSKVGNIAGCLVTSGIIRRNAKARLLRDNIVVAETVTISSL Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M YGGAGGRGGTSTVDGQRIPGVNGDSGQPPPPGYTGPPGAGGSGGAPGGL- MUL_4581|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GGGNGGTGWNGGKGDTGSGGGAGDGGKAPAGGTGGAGGDGGAGGKGGSGG Rv3507|M.tuberculosis_H37Rv NGNAGGNGGTGGASEDGDNGNAGSGATGGTGGNGGTGGDGGAAGLGGVA- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AGGNGGTGG-TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP----- TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01556|M.leprae_Br4923 RREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA-------- MAB_3131c|M.abscessus_ATCC_199 RREKDDVVEVRDGYECGLTLTYNDIKEGDVIEAYELREKERV-------- Mvan_1363|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_1829|M.marinum_M - MUL_4581|M.ulcerans_Agy99 - Mb3541|M.bovis_AF2122/97 V Rv3507|M.tuberculosis_H37Rv - Mflv_2178|M.gilvum_PYR-GCK - MSMEG_0868|M.smegmatis_MC2_155 - TH_3810|M.thermoresistible__bu - MLBr_01556|M.leprae_Br4923 - MAB_3131c|M.abscessus_ATCC_199 - Mvan_1363|M.vanbaalenii_PYR-1 - MAV_4827|M.avium_104 -