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KVGAVAAHFGRDVDRGVAKVVGIVEAAARDGVQLLVFPDACLGGYIGDLRRPDPSDPPPALDPDGPEIAA VIAAAGPMTVCVGYAEAAPGGSRYNSAICVSGDGVLGTHRKVHQPAGESLAYLAGDTFAAFDTPVGRLGM LIDYDKTFPESARALALDGAHIIAALSAWPASVTDRASRLPADRQSRLFDLYDCARAAENQVVVVSANQT GIMGSLRFLGQAKVVGPGGDVLATTRSKGGLARVDIDVEAEIARARRVLDHLAERRVDTYSTTARS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1219 | - | - | 100% (277) | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1224 | - | 3e-65 | 45.29% (276) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. vanbaalenii PYR-1 | Mvan_0813 | - | 2e-08 | 27.56% (254) | Nitrilase/cyanide hydratase and apolipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 3e-07 | 27.76% (263) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | Mflv_0095 | - | 4e-07 | 27.53% (247) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. tuberculosis H37Rv | Rv0480c | - | 3e-07 | 27.76% (263) | amidohydrolase |
| M. leprae Br4923 | MLBr_02449 | - | 5e-06 | 26.56% (256) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_0819 | - | 3e-20 | 34.23% (260) | carbon-nitrogen hydrolase family protein |
| M. marinum M | MMAR_0805 | - | 4e-08 | 25.81% (279) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 8e-12 | 28.04% (271) | carbon-nitrogen hydrolase |
| M. smegmatis MC2 155 | MSMEG_0566 | - | 1e-132 | 80.87% (277) | aliphatic amidase |
| M. thermoresistible (build 8) | TH_0873 | - | 7e-11 | 26.35% (277) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 2e-08 | 25.81% (279) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSG-TDPTANL
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSG-TDPTANL
MLBr_02449|M.leprae_Br4923 -------------------------------MRIALAQILSG-TDPVANL
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSG-TDPAANL
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSG-TDPAANL
MAV_4670|M.avium_104 -------------------------------MRIALAQILSG-TDPAANL
Mflv_0095|M.gilvum_PYR-GCK ---------------------------MRSGMRIALAQIQSS-TDPAANL
TH_0873|M.thermoresistible__bu -------------------------------MRIALAQIRSG-TDPSANL
Mvan_1219|M.vanbaalenii_PYR-1 -------------------------------MKVGAVAAHFG-RDVDRGV
MSMEG_0566|M.smegmatis_MC2_155 ----------------------------MAPVTLGAVAAHFG-RDLDRGV
MAB_0819|M.abscessus_ATCC_1997 ---------------------------MTGRLRLAVVQCSSQAADVQANL
: :. . * .:
MMAR_0805|M.marinum_M ELVRDYAERAADAGARLVVFPEATMCRFGVPLG-------PVAQPLDGPW
MUL_4548|M.ulcerans_Agy99 ELVRDYAERAADAGARLVVFPEATMCRFGVPLG-------PVAQPLDGPW
MLBr_02449|M.leprae_Br4923 RLVREYTGQATDAGATLVVFPEATMCRFGVPLG-------PVAEPIDGPW
Mb0490c|M.bovis_AF2122/97 QLVGKYAGEAATAGAQLVVFPEATMCRLGVPLR-------QVAEPVDGPW
Rv0480c|M.tuberculosis_H37Rv QLVGKYAGEAATAGAQLVVFPEATMCRLGVPLR-------QVAEPVDGPW
MAV_4670|M.avium_104 ALVGEYTRRAAGAGARLVVFPEATMCRFGVPLA-------PIAEPVDGPW
Mflv_0095|M.gilvum_PYR-GCK TLVEEYTRRAVDAGASLVLFPEATMVRFGVPLG-------GVAEPFDGPW
TH_0873|M.thermoresistible__bu NLVEEYTRRAAATGAGLVLFPEATMCRFGVSLK-------PVAEPLDGPW
Mvan_1219|M.vanbaalenii_PYR-1 AKVVGIVEAAARDGVQLLVFPDACLGGYIGDLRRPDPSDPPPALDPDGPE
MSMEG_0566|M.smegmatis_MC2_155 TKVVGIIESAARDGVDFLVFPDACLGGYIGDFHRPDPDDPPPALTLDGPE
MAB_0819|M.abscessus_ATCC_1997 ARLAETAHAAAAGDAQLVVFPEMYLTGYNIGEWDIR----DLAQSPDGPA
: *. .. :::**: : * ***
MMAR_0805|M.marinum_M ANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKI
MUL_4548|M.ulcerans_Agy99 ANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKI
MLBr_02449|M.leprae_Br4923 ANGVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDTHYHKI
Mb0490c|M.bovis_AF2122/97 ANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKI
Rv0480c|M.tuberculosis_H37Rv ANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKI
MAV_4670|M.avium_104 ADGVRRIATEANVTVIAGMFTPSGDGRVKNTLLVAN--SDDQAVTHYDKI
Mflv_0095|M.gilvum_PYR-GCK ANAVRDIAARAGIVVVAGMFVPSDDGRSFNTLLATGPGVEAR----YDKI
TH_0873|M.thermoresistible__bu ATAVREIAAGAGVVVVAGMFTPSGDGRVTNTLLATGPGVAAH----YHKI
Mvan_1219|M.vanbaalenii_PYR-1 IAAVIAAAGPMTVCVGYAEAAPGG-SRYNSAICVSGDGVLGT----HRKV
MSMEG_0566|M.smegmatis_MC2_155 IAAVVSAAGPMTVCVGYAESAPGG-GRYNAAVCVCGDGVLGT----YRKV
MAB_0819|M.abscessus_ATCC_1997 MQFIRQTACDADMHICVGYPERASDGQIYNSALICDPRGRVVLN--YRKS
: * : : . . .: : . : *
MMAR_0805|M.marinum_M HLYDAFGFAESRTVAPGHEPVVITVDD----VQVGLTVCYDIRFPALYTE
MUL_4548|M.ulcerans_Agy99 HLYDAFGFAESRTVAPGHEPVVITVDD----FQVGLTVCYDIRFPALYTE
MLBr_02449|M.leprae_Br4923 HLYDAFGFTESRTVTAGHEPVVITVDD----VQVGLTICYDIRFPALYTE
Mb0490c|M.bovis_AF2122/97 HLYDAFGFTESRTVAPGREPVVVVVDG----VRVGLTVCYDIRFPALYTE
Rv0480c|M.tuberculosis_H37Rv HLYDAFGFTESRTVAPGREPVVVVVDG----VRVGLTVCYDIRFPALYTE
MAV_4670|M.avium_104 HLYDAFGFTESRTVAPGREPVVVGVDG----VRVGLSVCYDIRFPELYTE
Mflv_0095|M.gilvum_PYR-GCK HLYDAFGFLESKTVAPGREPVVISVDTESGPVTVGLTLCYDIRFPELYVE
TH_0873|M.thermoresistible__bu HLYDAYGFTESRTVAPGSEPVTIDVGG----VRVGLTTCYDIRFPELYVE
Mvan_1219|M.vanbaalenii_PYR-1 HQPAG----ESLAYLAGDTFAAFDTPVG----RLGMLIDYDKTFPESARA
MSMEG_0566|M.smegmatis_MC2_155 HQPVG----ESLTYLAGDTFSTFDTPVG----RVGMLIDYDKTFPEAART
MAB_0819|M.abscessus_ATCC_1997 HLFGDT--ERNVFTRPGPQLPLAVVHG----VSVGLLICYDVEFPENVRA
* .. .* . :*: ** **
MMAR_0805|M.marinum_M LARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGD
MUL_4548|M.ulcerans_Agy99 LARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGD
MLBr_02449|M.leprae_Br4923 LARRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGG
Mb0490c|M.bovis_AF2122/97 LARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGD
Rv0480c|M.tuberculosis_H37Rv LARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGD
MAV_4670|M.avium_104 LARRGAQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGG
Mflv_0095|M.gilvum_PYR-GCK LADRGAEIITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAVGQAYPGD
TH_0873|M.thermoresistible__bu LARRGAELLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAVGQAYPGD
Mvan_1219|M.vanbaalenii_PYR-1 LALDGAHIIAALSAWPASVTDRASRLPADRQSRLFDLYDCARAAENQVVV
MSMEG_0566|M.smegmatis_MC2_155 LAMGGADIIAALSVWPASVTDRASRLPADRQSRLFDLYDCARAAENQVVL
MAB_0819|M.abscessus_ATCC_1997 LAMARADVVVVPTAN------------MEPFHAVCETVVPARAYENQLYV
** *.::.. : : * . :
MMAR_0805|M.marinum_M TASDPGGGSGAPRGVGGSLVASPLGEVVASAGSDPQLVVADIDLAK-VGA
MUL_4548|M.ulcerans_Agy99 TASDPGGGSGAPRGVGGSLVTSPLGEVVASAGSDPQLVVADIDLAK-VGA
MLBr_02449|M.leprae_Br4923 ALTDSGPSSAAPTGVGGSLVASPLGEVVASAGTESKLVVADIDVDN-VTT
Mb0490c|M.bovis_AF2122/97 ARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDN-VAA
Rv0480c|M.tuberculosis_H37Rv ARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDN-VAA
MAV_4670|M.avium_104 SLS----ASGAPTGVGGSLVASPLGEVVASAGAQPQLVLADIDVDR-VAQ
Mflv_0095|M.gilvum_PYR-GCK EIAALG-----PTGVGGSLVASALGEVLASAGDDPELLVCDVDLEA-ARK
TH_0873|M.thermoresistible__bu EIAAQG-----PTGVGGSLVASATGEVLAAAGPEPELLVADLDLDA-ARR
Mvan_1219|M.vanbaalenii_PYR-1 VSANQTGIMGSLRFLGQAKVVGPGGDVLATTRSKGGLARVDIDVEAEIAR
MSMEG_0566|M.smegmatis_MC2_155 VSSNQTGVMGNLRFLGQAKVVGPGGDILATTRSKGGLAKVEIDVHAEITR
MAB_0819|M.abscessus_ATCC_1997 AYANYCGNHDGLAYCGGSSIVGPDGTALARAGEGVGLLVADVDRAV-IDR
: * : :... * :. : * ::*
MMAR_0805|M.marinum_M ARDNIGVLRNQSRFTQTDKAQSRR
MUL_4548|M.ulcerans_Agy99 ARDNIGMLRNQSRFTQTDKAQSRR
MLBr_02449|M.leprae_Br4923 ARENIAVLRNRSHFA---------
Mb0490c|M.bovis_AF2122/97 ARDRIAVLRNQTDFVQIDKAQSRG
Rv0480c|M.tuberculosis_H37Rv ARDRIAVLRNQTDFVQIDKAQSRG
MAV_4670|M.avium_104 ARKTIAALSNRSDFAQVGRAESVG
Mflv_0095|M.gilvum_PYR-GCK ARQTVAVMQNRSGFAHRGKAESRG
TH_0873|M.thermoresistible__bu ARDTIAVLRNRSDVAQWGKAESVG
Mvan_1219|M.vanbaalenii_PYR-1 ARRVLDHLAERRVDTYSTTARS--
MSMEG_0566|M.smegmatis_MC2_155 ARRVLNHLTELRPGSYHVASEADR
MAB_0819|M.abscessus_ATCC_1997 TRSRHCFLEDRVARAISP------
:* : :