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MTGRLRLAVVQCSSQAADVQANLARLAETAHAAAAGDAQLVVFPEMYLTGYNIGEWDIRDLAQSPDGPAM QFIRQTACDADMHICVGYPERASDGQIYNSALICDPRGRVVLNYRKSHLFGDTERNVFTRPGPQLPLAVV HGVSVGLLICYDVEFPENVRALAMARADVVVVPTANMEPFHAVCETVVPARAYENQLYVAYANYCGNHDG LAYCGGSSIVGPDGTALARAGEGVGLLVADVDRAVIDRTRSRHCFLEDRVARAISP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0819 | - | - | 100% (266) | carbon-nitrogen hydrolase family protein |
| M. abscessus ATCC 19977 | MAB_4348c | - | 1e-50 | 41.25% (257) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2922c | - | 9e-47 | 38.04% (255) | carbon-nitrogen hydrolase family protein/ nitrilase/cyanide |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 6e-22 | 30.32% (277) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | Mflv_0095 | - | 7e-16 | 28.16% (277) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. tuberculosis H37Rv | Rv0480c | - | 3e-21 | 30.07% (276) | amidohydrolase |
| M. leprae Br4923 | MLBr_02449 | - | 5e-19 | 29.71% (276) | putative hydrolase |
| M. marinum M | MMAR_0805 | - | 3e-18 | 30.04% (263) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 1e-23 | 30.83% (266) | carbon-nitrogen hydrolase |
| M. smegmatis MC2 155 | MSMEG_6733 | - | 4e-32 | 36.36% (253) | hydrolase, carbon-nitrogen family protein |
| M. thermoresistible (build 8) | TH_0873 | - | 4e-20 | 31.23% (269) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 8e-18 | 29.66% (263) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_1219 | - | 4e-20 | 34.23% (260) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSGT-DPTANL
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSGT-DPTANL
MLBr_02449|M.leprae_Br4923 -------------------------------MRIALAQILSGT-DPVANL
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGT-DPAANL
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSGT-DPAANL
MAV_4670|M.avium_104 -------------------------------MRIALAQILSGT-DPAANL
Mflv_0095|M.gilvum_PYR-GCK ---------------------------MRSGMRIALAQIQSST-DPAANL
TH_0873|M.thermoresistible__bu -------------------------------MRIALAQIRSGT-DPSANL
MSMEG_6733|M.smegmatis_MC2_155 ----------------------------MRTVDVAVVQEPAVAGDVAANV
MAB_0819|M.abscessus_ATCC_1997 ---------------------------MTGRLRLAVVQCSSQAADVQANL
Mvan_1219|M.vanbaalenii_PYR-1 -------------------------------MKVGAVAAHFGR-DVDRGV
: :. . * .:
MMAR_0805|M.marinum_M ELVRDYAERAADAGARLVVFPEATMCRFG-----VPLGPVAQPLDGPWAN
MUL_4548|M.ulcerans_Agy99 ELVRDYAERAADAGARLVVFPEATMCRFG-----VPLGPVAQPLDGPWAN
MLBr_02449|M.leprae_Br4923 RLVREYTGQATDAGATLVVFPEATMCRFG-----VPLGPVAEPIDGPWAN
Mb0490c|M.bovis_AF2122/97 QLVGKYAGEAATAGAQLVVFPEATMCRLG-----VPLRQVAEPVDGPWAN
Rv0480c|M.tuberculosis_H37Rv QLVGKYAGEAATAGAQLVVFPEATMCRLG-----VPLRQVAEPVDGPWAN
MAV_4670|M.avium_104 ALVGEYTRRAAGAGARLVVFPEATMCRFG-----VPLAPIAEPVDGPWAD
Mflv_0095|M.gilvum_PYR-GCK TLVEEYTRRAVDAGASLVLFPEATMVRFG-----VPLGGVAEPFDGPWAN
TH_0873|M.thermoresistible__bu NLVEEYTRRAAATGAGLVLFPEATMCRFG-----VSLKPVAEPLDGPWAT
MSMEG_6733|M.smegmatis_MC2_155 RRAVAALAKHPG--ADLVVFPELFLCGYRLDV--VADAAIEMIPEPGPVA
MAB_0819|M.abscessus_ATCC_1997 ARLAETAHAAAAGDAQLVVFPEMYLTGYNIGE--WDIRDLAQSPDGPAMQ
Mvan_1219|M.vanbaalenii_PYR-1 AKVVGIVEAAARDGVQLLVFPDACLGGYIGDLRRPDPSDPPPALDPDGPE
. *::**: : :
MMAR_0805|M.marinum_M GVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIHL
MUL_4548|M.ulcerans_Agy99 GVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIHL
MLBr_02449|M.leprae_Br4923 GVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHL
Mb0490c|M.bovis_AF2122/97 GVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHL
Rv0480c|M.tuberculosis_H37Rv GVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHL
MAV_4670|M.avium_104 GVRRIATEANVTVIAGMFTPSGDGRVKNTLLVAN--SDDQAVTHYDKIHL
Mflv_0095|M.gilvum_PYR-GCK AVRDIAARAGIVVVAGMFVPSDDGRSFNTLLATGPGVEAR----YDKIHL
TH_0873|M.thermoresistible__bu AVREIAAGAGVVVVAGMFTPSGDGRVTNTLLATGPGVAAH----YHKIHL
MSMEG_6733|M.smegmatis_MC2_155 DLCAAAAAHDTAVVTGFAERSGD-LVYNSLLCIDR--TGAVAGVYRKTHL
MAB_0819|M.abscessus_ATCC_1997 FIRQTACDADMHICVGYPERASDGQIYNSALICDP--RGRVVLNYRKSHL
Mvan_1219|M.vanbaalenii_PYR-1 IAAVIAAAGPMTVCVGYAEAAPGGSRYNSAICVSG---DGVLGTHRKVHQ
* : .* : *: : . : * *
MMAR_0805|M.marinum_M YDAFGFAESRTVAPGHEPVVITVDD----VQVGLTVCYDIRFPALYTELA
MUL_4548|M.ulcerans_Agy99 YDAFGFAESRTVAPGHEPVVITVDD----FQVGLTVCYDIRFPALYTELA
MLBr_02449|M.leprae_Br4923 YDAFGFTESRTVTAGHEPVVITVDD----VQVGLTICYDIRFPALYTELA
Mb0490c|M.bovis_AF2122/97 YDAFGFTESRTVAPGREPVVVVVDG----VRVGLTVCYDIRFPALYTELA
Rv0480c|M.tuberculosis_H37Rv YDAFGFTESRTVAPGREPVVVVVDG----VRVGLTVCYDIRFPALYTELA
MAV_4670|M.avium_104 YDAFGFTESRTVAPGREPVVVGVDG----VRVGLSVCYDIRFPELYTELA
Mflv_0095|M.gilvum_PYR-GCK YDAFGFLESKTVAPGREPVVISVDTESGPVTVGLTLCYDIRFPELYVELA
TH_0873|M.thermoresistible__bu YDAYGFTESRTVAPGSEPVTIDVGG----VRVGLTTCYDIRFPELYVELA
MSMEG_6733|M.smegmatis_MC2_155 FG---AECEAFAT-GDRLEVIEVDG----LRVGPMICFDVEFPEIARTLA
MAB_0819|M.abscessus_ATCC_1997 FGD--TERNVFTRPGPQLPLAVVHG----VSVGLLICYDVEFPENVRALA
Mvan_1219|M.vanbaalenii_PYR-1 PAG----ESLAYLAGDTFAAFDTPVG----RLGMLIDYDKTFPESARALA
. * . :* :* ** **
MMAR_0805|M.marinum_M RRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDTA
MUL_4548|M.ulcerans_Agy99 RRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDTA
MLBr_02449|M.leprae_Br4923 RRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGAL
Mb0490c|M.bovis_AF2122/97 RRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDAR
Rv0480c|M.tuberculosis_H37Rv RRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDAR
MAV_4670|M.avium_104 RRGAQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGGSL
Mflv_0095|M.gilvum_PYR-GCK DRGAEIITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAVGQAYPGDEI
TH_0873|M.thermoresistible__bu RRGAELLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAVGQAYPGDEI
MSMEG_6733|M.smegmatis_MC2_155 LSGVDLFVVSSANMFPYHHDHRVACLSRALENRTPLVYSNLIGAEAG---
MAB_0819|M.abscessus_ATCC_1997 MARADVVVVPTANMEPFHAVCETVVPARAYENQLYVAYANYCGNHDG---
Mvan_1219|M.vanbaalenii_PYR-1 LDGAHIIAALSAWPASVTDRASRLPADRQSRLFDLYDCARAAENQVVVVS
..:... :: * :
MMAR_0805|M.marinum_M SDPGGGSGAPRGVGGSLVASPLGEVVASAGSDPQLVVADIDLAK-VGAAR
MUL_4548|M.ulcerans_Agy99 SDPGGGSGAPRGVGGSLVTSPLGEVVASAGSDPQLVVADIDLAK-VGAAR
MLBr_02449|M.leprae_Br4923 TDSGPSSAAPTGVGGSLVASPLGEVVASAGTESKLVVADIDVDN-VTTAR
Mb0490c|M.bovis_AF2122/97 TGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDN-VAAAR
Rv0480c|M.tuberculosis_H37Rv TGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDN-VAAAR
MAV_4670|M.avium_104 S----ASGAPTGVGGSLVASPLGEVVASAGAQPQLVLADIDVDR-VAQAR
Mflv_0095|M.gilvum_PYR-GCK AALG-----PTGVGGSLVASALGEVLASAGDDPELLVCDVDLEA-ARKAR
TH_0873|M.thermoresistible__bu AAQG-----PTGVGGSLVASATGEVLAAAGPEPELLVADLDLDA-ARRAR
MSMEG_6733|M.smegmatis_MC2_155 ---------LTFVGGSRVVDAGGELLVECGGEVSVARCRVTPAT-ATSTE
MAB_0819|M.abscessus_ATCC_1997 ---------LAYCGGSSIVGPDGTALARAGEGVGLLVADVDRAV-IDRTR
Mvan_1219|M.vanbaalenii_PYR-1 ANQTGIMGSLRFLGQAKVVGPGGDVLATTRSKGGLARVDIDVEAEIARAR
* : :... * :. : : :.
MMAR_0805|M.marinum_M DNIGVLRNQSRFTQTDKAQSRR
MUL_4548|M.ulcerans_Agy99 DNIGMLRNQSRFTQTDKAQSRR
MLBr_02449|M.leprae_Br4923 ENIAVLRNRSHFA---------
Mb0490c|M.bovis_AF2122/97 DRIAVLRNQTDFVQIDKAQSRG
Rv0480c|M.tuberculosis_H37Rv DRIAVLRNQTDFVQIDKAQSRG
MAV_4670|M.avium_104 KTIAALSNRSDFAQVGRAESVG
Mflv_0095|M.gilvum_PYR-GCK QTVAVMQNRSGFAHRGKAESRG
TH_0873|M.thermoresistible__bu DTIAVLRNRSDVAQWGKAESVG
MSMEG_6733|M.smegmatis_MC2_155 DDVDYLRHRRPELYRLK-----
MAB_0819|M.abscessus_ATCC_1997 SRHCFLEDRVARAISP------
Mvan_1219|M.vanbaalenii_PYR-1 RVLDHLAERRVDTYSTTARS--
: .: