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APVTLGAVAAHFGRDLDRGVTKVVGIIESAARDGVDFLVFPDACLGGYIGDFHRPDPDDPPPALTLDGPE IAAVVSAAGPMTVCVGYAESAPGGGRYNAAVCVCGDGVLGTYRKVHQPVGESLTYLAGDTFSTFDTPVGR VGMLIDYDKTFPEAARTLAMGGADIIAALSVWPASVTDRASRLPADRQSRLFDLYDCARAAENQVVLVSS NQTGVMGNLRFLGQAKVVGPGGDILATTRSKGGLAKVEIDVHAEITRARRVLNHLTELRPGSYHVASEAD R*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0566 | - | - | 100% (282) | aliphatic amidase |
| M. smegmatis MC2 155 | MSMEG_0571 | - | 8e-70 | 48.24% (284) | hydrolase, carbon-nitrogen family protein |
| M. smegmatis MC2 155 | MSMEG_6733 | - | 1e-20 | 29.75% (279) | hydrolase, carbon-nitrogen family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0095 | - | 6e-05 | 24.80% (254) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_02449 | - | 6e-05 | 25.91% (247) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_0819 | - | 2e-17 | 31.15% (260) | carbon-nitrogen hydrolase family protein |
| M. marinum M | MMAR_0805 | - | 6e-07 | 26.15% (260) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 8e-07 | 25.20% (250) | carbon-nitrogen hydrolase |
| M. thermoresistible (build 8) | TH_0873 | - | 2e-11 | 27.82% (266) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 4e-07 | 26.15% (260) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_1219 | - | 1e-132 | 80.87% (277) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M ----MRIALAQILSG-TDPTANLELVRDYAERAADAGARLVVFPEATMCR
MUL_4548|M.ulcerans_Agy99 ----MRIALAQILSG-TDPTANLELVRDYAERAADAGARLVVFPEATMCR
MLBr_02449|M.leprae_Br4923 ----MRIALAQILSG-TDPVANLRLVREYTGQATDAGATLVVFPEATMCR
MAV_4670|M.avium_104 ----MRIALAQILSG-TDPAANLALVGEYTRRAAGAGARLVVFPEATMCR
Mflv_0095|M.gilvum_PYR-GCK MRSGMRIALAQIQSS-TDPAANLTLVEEYTRRAVDAGASLVLFPEATMVR
TH_0873|M.thermoresistible__bu ----MRIALAQIRSG-TDPSANLNLVEEYTRRAAATGAGLVLFPEATMCR
MSMEG_0566|M.smegmatis_MC2_155 -MAPVTLGAVAAHFG-RDLDRGVTKVVGIIESAARDGVDFLVFPDACLGG
Mvan_1219|M.vanbaalenii_PYR-1 ----MKVGAVAAHFG-RDVDRGVAKVVGIVEAAARDGVQLLVFPDACLGG
MAB_0819|M.abscessus_ATCC_1997 MTGRLRLAVVQCSSQAADVQANLARLAETAHAAAAGDAQLVVFPEMYLTG
: :. . * .: : *. .. :::**: :
MMAR_0805|M.marinum_M FGVPLG-------PVAQPLDGPWANGVRRIAAQTGITVVAGMFTPADAGR
MUL_4548|M.ulcerans_Agy99 FGVPLG-------PVAQPLDGPWANGVRRIAAQTGITVVAGMFTPADAGR
MLBr_02449|M.leprae_Br4923 FGVPLG-------PVAEPIDGPWANGVRQIATEAGITIIAGIFTPADDGR
MAV_4670|M.avium_104 FGVPLA-------PIAEPVDGPWADGVRRIATEANVTVIAGMFTPSGDGR
Mflv_0095|M.gilvum_PYR-GCK FGVPLG-------GVAEPFDGPWANAVRDIAARAGIVVVAGMFVPSDDGR
TH_0873|M.thermoresistible__bu FGVSLK-------PVAEPLDGPWATAVREIAAGAGVVVVAGMFTPSGDGR
MSMEG_0566|M.smegmatis_MC2_155 YIGDFHRPDPDDPPPALTLDGPEIAAVVSAAGPMTVCVGYAESAPGG-GR
Mvan_1219|M.vanbaalenii_PYR-1 YIGDLRRPDPSDPPPALDPDGPEIAAVIAAAGPMTVCVGYAEAAPGG-SR
MAB_0819|M.abscessus_ATCC_1997 YNIGEWDIR----DLAQSPDGPAMQFIRQTACDADMHICVGYPERASDGQ
: * *** : * : : . .. .:
MMAR_0805|M.marinum_M VSNTLFAAGPGAPNQPDDHYHKIHLYDAFGFAESRTVAPGHEPVVITVDD
MUL_4548|M.ulcerans_Agy99 VSNTLFAAGPGAPNQPDDHYHKIHLYDAFGFAESRTVAPGHEPVVITVDD
MLBr_02449|M.leprae_Br4923 VMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFTESRTVTAGHEPVVITVDD
MAV_4670|M.avium_104 VKNTLLVAN--SDDQAVTHYDKIHLYDAFGFTESRTVAPGREPVVVGVDG
Mflv_0095|M.gilvum_PYR-GCK SFNTLLATGPGVEAR----YDKIHLYDAFGFLESKTVAPGREPVVISVDT
TH_0873|M.thermoresistible__bu VTNTLLATGPGVAAH----YHKIHLYDAYGFTESRTVAPGSEPVTIDVGG
MSMEG_0566|M.smegmatis_MC2_155 YNAAVCVCGDGVLGTYRKVHQPVG--ESLTYLAGDTFSTFDTPVG-----
Mvan_1219|M.vanbaalenii_PYR-1 YNSAICVSGDGVLGTHRKVHQPAG--ESLAYLAGDTFAAFDTPVG-----
MAB_0819|M.abscessus_ATCC_1997 IYNSALICDP--RGRVVLNYRKSH---LFGDTERNVFTRPGPQLPLAVVH
: . : ..: :
MMAR_0805|M.marinum_M ----VQVGLTVCYDIRFPALYTELARRGAELIVVSASWGSGPGKLDQWTL
MUL_4548|M.ulcerans_Agy99 ----FQVGLTVCYDIRFPALYTELARRGAELIVVSASWGSGPGKLDQWTL
MLBr_02449|M.leprae_Br4923 ----VQVGLTICYDIRFPALYTELARRGAQLIVVCASWGSGAGKLEQWTL
MAV_4670|M.avium_104 ----VRVGLSVCYDIRFPELYTELARRGAQLIAVCASWGAGPGKLDQWTL
Mflv_0095|M.gilvum_PYR-GCK ESGPVTVGLTLCYDIRFPELYVELADRGAEIITAHASWGTGPGKLEQWTL
TH_0873|M.thermoresistible__bu ----VRVGLTTCYDIRFPELYVELARRGAELLTVHASWGSGPGKLEQWTL
MSMEG_0566|M.smegmatis_MC2_155 -----RVGMLIDYDKTFPEAARTLAMGGADIIAALSVWPASVTDRASRLP
Mvan_1219|M.vanbaalenii_PYR-1 -----RLGMLIDYDKTFPESARALALDGAHIIAALSAWPASVTDRASRLP
MAB_0819|M.abscessus_ATCC_1997 G---VSVGLLICYDVEFPENVRALAMARADVVVVPTAN------------
:*: ** ** ** *.::.. :
MMAR_0805|M.marinum_M LARARALDSASYVAAAGQADPGDTASDPGGGSGAPRGVGGSLVASPLGEV
MUL_4548|M.ulcerans_Agy99 LARARALDSASYVAAAGQADPGDTASDPGGGSGAPRGVGGSLVTSPLGEV
MLBr_02449|M.leprae_Br4923 LARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEV
MAV_4670|M.avium_104 LARARALDSMSYIAAAGQADPGGSLS----ASGAPTGVGGSLVASPLGEV
Mflv_0095|M.gilvum_PYR-GCK LARARAIDTSSVVAAVGQAYPGDEIA-----ALGPTGVGGSLVASALGEV
TH_0873|M.thermoresistible__bu LARARALDTTCVVAAVGQAYPGDEIA-----AQGPTGVGGSLVASATGEV
MSMEG_0566|M.smegmatis_MC2_155 ADRQSRLFDLYDCARAAENQVVLVSSNQTGVMGNLRFLGQAKVVGPGGDI
Mvan_1219|M.vanbaalenii_PYR-1 ADRQSRLFDLYDCARAAENQVVVVSANQTGIMGSLRFLGQAKVVGPGGDV
MAB_0819|M.abscessus_ATCC_1997 MEPFHAVCETVVPARAYENQLYVAYANYCGNHDGLAYCGGSSIVGPDGTA
: * . : : * : :... *
MMAR_0805|M.marinum_M VASAGSDPQLVVADIDLAK-VGAARDNIGVLRNQSRFTQTDKAQSRR
MUL_4548|M.ulcerans_Agy99 VASAGSDPQLVVADIDLAK-VGAARDNIGMLRNQSRFTQTDKAQSRR
MLBr_02449|M.leprae_Br4923 VASAGTESKLVVADIDVDN-VTTARENIAVLRNRSHFA---------
MAV_4670|M.avium_104 VASAGAQPQLVLADIDVDR-VAQARKTIAALSNRSDFAQVGRAESVG
Mflv_0095|M.gilvum_PYR-GCK LASAGDDPELLVCDVDLEA-ARKARQTVAVMQNRSGFAHRGKAESRG
TH_0873|M.thermoresistible__bu LAAAGPEPELLVADLDLDA-ARRARDTIAVLRNRSDVAQWGKAESVG
MSMEG_0566|M.smegmatis_MC2_155 LATTRSKGGLAKVEIDVHAEITRARRVLNHLTELRPGSYHVASEADR
Mvan_1219|M.vanbaalenii_PYR-1 LATTRSKGGLARVDIDVEAEIARARRVLDHLAERRVDTYSTTARS--
MAB_0819|M.abscessus_ATCC_1997 LARAGEGVGLLVADVDRAV-IDRTRSRHCFLEDRVARAISP------
:* : * ::* :* : : :