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TFFARIAAAVLLAAGLLTAGAAPQAQAFSRDGLPIEQLDVPSPSMGRHIRVEFQGGGPHSVLLLDGLRAQ DDYNGWDINTAAFEWFHESGVSVIMPVGGVASFYADWYRPAKNRNGTLTYKWETFLTRELPAWLAANRGQ DPFGNAVVGLSMSGSAALTLAAWYPRQYKFAASLSGYLAPSRGLWPALIDIAMQDAGGFDSYDMWGKPGS PAWLRADPTVNVNRLVANRTALWIYCGNGVTSDLDTGSDFGRNFSAGYLETITVSTNKEFQQKYLAAGGR NAVFNFPPNGTHSWGYWGAQLQAMKADIVRLLAPPPPPPPPPGLPPPGAPVPPPPAMPVPAPAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1190 | - | - | 100% (345) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | e-115 | 62.82% (312) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_5880 | - | e-112 | 60.45% (311) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-113 | 61.13% (319) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. gilvum PYR-GCK | Mflv_5146 | - | 1e-178 | 85.63% (341) | putative esterase |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-113 | 61.13% (319) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-108 | 58.41% (315) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_0175 | - | 1e-100 | 57.59% (316) | antigen 85-C precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-114 | 59.82% (331) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-113 | 57.70% (331) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_6583 | - | 1e-144 | 69.32% (339) | antigen 85-C |
| M. thermoresistible (build 8) | TH_1495 | fbpA | 1e-138 | 69.00% (329) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-115 | 59.82% (331) | secreted antigen 85-C FbpC |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1190|M.vanbaalenii_PYR-1 -----------------MTFFARIAAAVLLAAGLLTAGA--APQAQAFSR
Mflv_5146|M.gilvum_PYR-GCK -----------------MTFFARIAVAVLLAAGLLTVAP--SPQAAAFSR
TH_1495|M.thermoresistible__bu --------VANRVAGRAVSDLMRAIGVLLLVLPVTVAVVNRAPVAAAYSR
MSMEG_6583|M.smegmatis_MC2_155 --------MKPSFFSTLSRRVAAGAATVLMLAGLIATGP--VPQAAAYSR
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGD-TAIAVAFSK
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGG-SPVAGAFSK
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGG-PATAGAFSR
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGG-PATAGAFSR
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGG-AATAGAFSR
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGG-AATAGAFSR
MAB_0175|M.abscessus_ATCC_1997 ----------MSVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSR
. : : . . * *:*:
Mvan_1190|M.vanbaalenii_PYR-1 DGLPIEQLDVPSPSMGRHIRVEFQGGGPHSVLLLDGLRAQDDYNGWDINT
Mflv_5146|M.gilvum_PYR-GCK PGLPIEQLDVPSPSMGRTIRVEFQGGGPHSVLLLDGLRAQDDFNGWDINT
TH_1495|M.thermoresistible__bu DGLPVERLAVPSPSMGRDIIVQFQGGGPHSVYLLDGLRAQEDANGWDINT
MSMEG_6583|M.smegmatis_MC2_155 DGLPVERLQVPSAAMGRDITVQFQGGGPHALYLLDGLRAQDDANGWDINT
MLBr_02655|M.leprae_Br4923 PGLPVEYLQVPSPSMGHDIKIQFQGGGQHAVYLLDGLRAQEDYNGWDINT
MAV_5183|M.avium_104 PGLPVEYLEVPSPSMGRNIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINT
Mb0134c|M.bovis_AF2122/97 PGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINT
Rv0129c|M.tuberculosis_H37Rv PGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINT
MMAR_0328|M.marinum_M PGLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGWDINT
MUL_4793|M.ulcerans_Agy99 PGLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGWDINT
MAB_0175|M.abscessus_ATCC_1997 EGLPVEYLDVYSNSMGRNIRVEFQGGGPKAVYLLDGLRAQDDFNGWDINT
***:* * : * :**: * ::***** ::: ********:* *******
Mvan_1190|M.vanbaalenii_PYR-1 AAFEWFHESGVSVIMPVGGVASFYADWYRPAKNRNGTLTYKWETFLTREL
Mflv_5146|M.gilvum_PYR-GCK SAFEWFYESGVSVIMPVGGQSSFYADWYRPARNNNATLTYKWETFLTNEL
TH_1495|M.thermoresistible__bu AAFEWFHDSGISVVMPVGGESSFYTDWYQPARSRSGTVTYKWETFLTKEL
MSMEG_6583|M.smegmatis_MC2_155 AAFEWFYQSGISVVMPVGGQSSFYTDWYRPAVGSAGTTTYKWETFLTREL
MLBr_02655|M.leprae_Br4923 PAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFLTQEM
MAV_5183|M.avium_104 PAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFLTQEM
Mb0134c|M.bovis_AF2122/97 PAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREM
Rv0129c|M.tuberculosis_H37Rv PAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREM
MMAR_0328|M.marinum_M PAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTREM
MUL_4793|M.ulcerans_Agy99 PAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTREM
MAB_0175|M.abscessus_ATCC_1997 AAFEWFYQSGISVVMPVGGQSSFYTDWYSPSALNKQPYTYKWETFLTQEL
.*** ::.**:**:***** :***::** *: *********.*:
Mvan_1190|M.vanbaalenii_PYR-1 PAWLAANRGQDPFGNAVVGLSMSGSAALTLAAWYPRQYKFAASLSGYLAP
Mflv_5146|M.gilvum_PYR-GCK PTWLATHRGQDPFGNAVVGLSMSGSAALTLAAWYPRQYKFAASLSGYLAP
TH_1495|M.thermoresistible__bu PAWLAENRGQDPNGNAVVGLSMSGGAALNLATWYPQQFIFASSLSGYLSP
MSMEG_6583|M.smegmatis_MC2_155 PAWLAANRGVEPTGNAVVGLSMSGGAALNLATWYPQQFIFAGALSGFLNP
MLBr_02655|M.leprae_Br4923 PSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSGFLNP
MAV_5183|M.avium_104 PLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNP
Mb0134c|M.bovis_AF2122/97 PAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNP
Rv0129c|M.tuberculosis_H37Rv PAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNP
MMAR_0328|M.marinum_M PAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLNP
MUL_4793|M.ulcerans_Agy99 PAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLNP
MAB_0175|M.abscessus_ATCC_1997 PAYLATNKQISATGNGVVGLSMSGGAALILAAFHPAQFRFAGSLSGFLNP
* :: :: . **..*******.:** **:::* *: :*.:***:* *
Mvan_1190|M.vanbaalenii_PYR-1 SRGLWPALIDIAMQDAGGFDSYDMWGKPGSPAWLRADPTVNVNRLVANRT
Mflv_5146|M.gilvum_PYR-GCK SQKFWPSLIDIAMQDAGGFDSFDMWGKPGSPAWLRADPMLNINRLVANRT
TH_1495|M.thermoresistible__bu SQGLWPTLIGVAMQDAGGYNARDMWGPTSDIAWRRNDPTVNVARLAANNT
MSMEG_6583|M.smegmatis_MC2_155 SQGLWPTMIGFAMKDAGGYNSADMWGLANDPAWRRNDPMVNINRLVANNT
MLBr_02655|M.leprae_Br4923 SEGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNT
MAV_5183|M.avium_104 SEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNT
Mb0134c|M.bovis_AF2122/97 SEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNT
Rv0129c|M.tuberculosis_H37Rv SEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNT
MMAR_0328|M.marinum_M SEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNT
MUL_4793|M.ulcerans_Agy99 SEGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNT
MAB_0175|M.abscessus_ATCC_1997 STIFMTNAIRVAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGT
* . * .** *:*.:. .*** . . ** * ** :: *.* *
Mvan_1190|M.vanbaalenii_PYR-1 ALWIYCGNGVTSDLDTGSDFGRNFSAGYLETITVSTNKEFQQKYLAAGGR
Mflv_5146|M.gilvum_PYR-GCK ALWVYCGNGVASDLDTGTDLGVNISAGSLETITIATNKEFRDKYLAAGGR
TH_1495|M.thermoresistible__bu ALWIYCGSGAMSDLDSGTDFGNNFSAQYLENITLSSNKEFQQKYVAAGGR
MSMEG_6583|M.smegmatis_MC2_155 AIWVYCGNGAPSDLDAAGDFGQLYSAQFLENITVNTNKEFQKRYLAAGGH
MLBr_02655|M.leprae_Br4923 RIWVYCGNGAPNELG-----GDNIPAKFLESLTLSTNEIFQNTYAASGGR
MAV_5183|M.avium_104 RIWVYCGNGTPSDLG-----GDNVPAKFLEGLTLRTNEQFQNNYAAAGGR
Mb0134c|M.bovis_AF2122/97 RIWVYCGNGTPSDLG-----GDNIPAKFLEGLTLRTNQTFRDTYAADGGR
Rv0129c|M.tuberculosis_H37Rv RIWVYCGNGTPSDLG-----GDNIPAKFLEGLTLRTNQTFRDTYAADGGR
MMAR_0328|M.marinum_M RIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLASGGR
MUL_4793|M.ulcerans_Agy99 RIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLASGGR
MAB_0175|M.abscessus_ATCC_1997 RLYIYCAPGGSTPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGR
:::**. * . :. * .* ** ::: *: *:. * * **:
Mvan_1190|M.vanbaalenii_PYR-1 NAVFNFPPNGTHSWGYWGAQLQAMKADIVRLLAPPPPPPPPPGLPPPGAP
Mflv_5146|M.gilvum_PYR-GCK NAIFNFPPNGTHSWGYWGAQLQAMKPDIVRLLNPPPPPPPAP--LPPGAP
TH_1495|M.thermoresistible__bu NAIFNFPANGTHSWAYWGSQLQEMKPQLLRVLGVTTAAPQTP------AP
MSMEG_6583|M.smegmatis_MC2_155 NAVFNFPPNGTHAWGYWGAQLQAMKPDLLRVLGVGAPAPAAPAAPAPAAP
MLBr_02655|M.leprae_Br4923 NGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA-----------
MAV_5183|M.avium_104 NGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQPAQPAQP
Mb0134c|M.bovis_AF2122/97 NGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA----
Rv0129c|M.tuberculosis_H37Rv NGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA----
MMAR_0328|M.marinum_M NGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPAAP
MUL_4793|M.ulcerans_Agy99 NGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPAAP
MAB_0175|M.abscessus_ATCC_1997 NANFVFPASGNHSWPYWGQQLQALKGDLIATLNG----------------
*. * **..*.*:* **. ** :* :: *
Mvan_1190|M.vanbaalenii_PYR-1 VPPPP-------AMPVPAPAG-----------------------------
Mflv_5146|M.gilvum_PYR-GCK LPPPP-------APPAPPAPR-----------------------------
TH_1495|M.thermoresistible__bu AAPPI-------AGAHPAGHP-----------------------------
MSMEG_6583|M.smegmatis_MC2_155 VPAAPGMPVAPVAPAVPGAQGLPAAPAYPVAPGVQGVPGVQGVPAAPASP
MLBr_02655|M.leprae_Br4923 --------------------------------------------------
MAV_5183|M.avium_104 AQPAQP--------AQPAT-------------------------------
Mb0134c|M.bovis_AF2122/97 --------------------------------------------------
Rv0129c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0328|M.marinum_M VAPAA---------------------------------------------
MUL_4793|M.ulcerans_Agy99 VAPAA---------------------------------------------
MAB_0175|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_1190|M.vanbaalenii_PYR-1 ----------
Mflv_5146|M.gilvum_PYR-GCK ----------
TH_1495|M.thermoresistible__bu ----------
MSMEG_6583|M.smegmatis_MC2_155 AVALPATRPV
MLBr_02655|M.leprae_Br4923 ----------
MAV_5183|M.avium_104 ----------
Mb0134c|M.bovis_AF2122/97 ----------
Rv0129c|M.tuberculosis_H37Rv ----------
MMAR_0328|M.marinum_M ----------
MUL_4793|M.ulcerans_Agy99 ----------
MAB_0175|M.abscessus_ATCC_1997 ----------