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VDRRAQQRLALGEFLRARRRAAVRAELGLPDMPRSRTSGLRREEVAVQAGVSVTWYTWLEQGRDINPSRQ VLDAIARALRLSPSEHDYVLALGGYTVDHAVTAGPPPPQIQRFLDALGGHPAFAITSDWGIAAWNTAYAA LYPNIERVPPPDRNLLWLVFMDPAIRELLPDWDADSRRFLAEFRADAGPMVGEPSYTALVSRLSSESPHF ATAWRAADIERFTSRERLFRHPVVGELRLEHHQVAPVDVPDIQIVAYLPEPGSVAAERLRRLVGQAGDTA R
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1162 | - | - | 100% (281) | XRE family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0930 | - | 6e-49 | 37.81% (283) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5465 | - | 2e-32 | 33.33% (273) | XRE family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5170 | - | 1e-133 | 82.56% (281) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4641 | - | 2e-81 | 53.51% (271) | putative DNA-binding protein |
| M. marinum M | MMAR_3947 | - | 4e-12 | 34.04% (141) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1289 | - | 3e-81 | 55.64% (257) | hypothetical protein MSMEG_1289 |
| M. thermoresistible (build 8) | TH_1958 | - | 2e-07 | 28.77% (146) | transcriptional regulator, XRE family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1162|M.vanbaalenii_PYR-1 MDRRAQQRLALGEFLRARRRAAVRAELGLPDMPRSRTSGLRREEVAVQAG
Mflv_5170|M.gilvum_PYR-GCK MDTRAQRRLALGEFLRARREAIRRADVGLPELPRARTGGLRREEVAVTAG
MAB_4641|M.abscessus_ATCC_1997 MAGTDERRRELGAFLRVRREHLVRADYGLPPVGRSRTTGLRREEIAYLSG
MSMEG_1289|M.smegmatis_MC2_155 MATQEEHRAELGAFLRASRERLNRAEFGLPPAGRNRTVGLRREEVSYLSG
MMAR_3947|M.marinum_M MPNR-------GGFVHAAR----------------ERAGLTCRELAEKAG
TH_1958|M.thermoresistible__bu VESRP------ASGHDAEVTRTAAPAFGAMLRDWRRRRRLSQLDLALEAG
: . . . * ::: :*
Mvan_1162|M.vanbaalenii_PYR-1 VSVTWYTWLEQGRDINPSRQVLDAIARALRLSPSEHDYVLALGGYT---V
Mflv_5170|M.gilvum_PYR-GCK VSVTWYTWLEQGRDINPSKQVLDAVADALRLSPAEHEYVLALGGYA---V
MAB_4641|M.abscessus_ATCC_1997 VSVTWYTWLEQGRDINPSRQVLEAIALEMRLSAAERTYLLELAGFAPLPH
MSMEG_1289|M.smegmatis_MC2_155 VSVTWYTWLEQGRDINPSRQVLDAVSRTLRLSAAQHRYVLTLAGFAPVSA
MMAR_3947|M.marinum_M CSLRYVHDIEQG--CSPSIRVLNGLVRALQLSAWEQRFLFAACGRILP--
TH_1958|M.thermoresistible__bu VSARHVSFMETGR-AAPSRTMVLRLAEVLEVPPREQNGLLVAAGYAPVYA
* :* * ** :: : :.:.. :: :: *
Mvan_1162|M.vanbaalenii_PYR-1 DHAVTA---GPPPPQIQRFLDALGGHPAFAITSDWGIAAWNTAYAALYPN
Mflv_5170|M.gilvum_PYR-GCK DAAVSR---GPLPPHIQHFLDALEGYPAFAITPDWGIAAWNTTYAALYPN
MAB_4641|M.abscessus_ATCC_1997 SATPDP---APVPDHLLRLVENLVPSPAFVVSADWSIGGWNRAYELLYPG
MSMEG_1289|M.smegmatis_MC2_155 APADDV---TDVPGHVQRLLDAIGDNPAYALTPEWGIAGWNAAYQRLYPN
MMAR_3947|M.marinum_M DPALTD---TDIS---QRYLDALQPHPAAALHPSWRFKAWNQQWQRLFQG
TH_1958|M.thermoresistible__bu ERDLDDPEMAAVRHGVQRVLDAHDPYPCVAVDRGWRVVQTNAGAAVLLDG
: :: *. .: * . * * .
Mvan_1162|M.vanbaalenii_PYR-1 IERVPPPDRNLLWLVFMDPAIRELLPDWDADSRRFLAEFRADAGPMVGEP
Mflv_5170|M.gilvum_PYR-GCK VERVPETDRNLLWLVFTDPYIHELLPNWDTDSRRFLAEFRADAGPRVGEP
MAB_4641|M.abscessus_ATCC_1997 IASIVPADRNLLRFIFTDPYVRQMLPDWPITSRRFLAEYRAEAGALLGDP
MSMEG_1289|M.smegmatis_MC2_155 VATTPPAERNLLWAVFTDPFVRDLLDDWPVTSQRFLAEFRAEIGPRLGNP
MMAR_3947|M.marinum_M VLLAP----SMHQWLYLSTTSRRILRNWDEVSQWCVGWLR--YGLAVDVD
TH_1958|M.thermoresistible__bu VADHLLEQPNALRIALHPDGLAPRIRNLAQWRHHLISRLRREVALSR-AP
: . : : : :. * .
Mvan_1162|M.vanbaalenii_PYR-1 SYTALVSRLSSESPHFATAWRAA----DIERFTSRERLFRHP--------
Mflv_5170|M.gilvum_PYR-GCK SYTALVSRLSSESPHFAAAWQAT----SIERFTSRERLFRHP--------
MAB_4641|M.abscessus_ATCC_1997 RHRALVDRLQQQSPEFARAWAEH----EVGRFTSRERRFHHP--------
MSMEG_1289|M.smegmatis_MC2_155 TLLGLIERLSEASDEFRAGWERH----DIRGFESRERVFHHP--------
MMAR_3947|M.marinum_M AVKPMVSALMPVT-EFRREWEAQ----VIPVDPATRLWVVRD--------
TH_1958|M.thermoresistible__bu GAVALLAEIESYPGGFDDPGDLGGVVVPLELYTTSRRLLSFLSTVTTFGT
:: : . * : : . .
Mvan_1162|M.vanbaalenii_PYR-1 --VVGELRLEHHQVAPVDVPDIQIVAYLPEPGSVAAERLRRLVGQAGDTA
Mflv_5170|M.gilvum_PYR-GCK --AAGELRLEHHQVAPVDVPDIQIVAYLPVPDSVASERLRMLTGQA-DTA
MAB_4641|M.abscessus_ATCC_1997 --EAGELIFEHHRLSPSDLPDLHIVIYLPLDGTNTRTKLEALLSGGR---
MSMEG_1289|M.smegmatis_MC2_155 --EFGVVTYEHHQLRPSDQPELQLVVYTPTHRNP----------------
MMAR_3947|M.marinum_M --GGTELRIDMRFWHASPMPGGLLLGVILDAG------------------
TH_1958|M.thermoresistible__bu ALDLTAAELSIEAFLPADERTASALAGPTSPAAASFPDPDTGTAAARQP-
. . . :
Mvan_1162|M.vanbaalenii_PYR-1 R
Mflv_5170|M.gilvum_PYR-GCK R
MAB_4641|M.abscessus_ATCC_1997 -
MSMEG_1289|M.smegmatis_MC2_155 -
MMAR_3947|M.marinum_M -
TH_1958|M.thermoresistible__bu -