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GVLEAFLSTWSKARATFGAGTPEPGSSYDESATLTGLSRDLDEAAPTAHWSGGAAEAYGTANADHRRVVG ELGLLDRRLADQIDRSAQIVTAGRQDLEAIREWVVAAAASVPRNRAGELMVAPIVRQGLSQLAEVVTRAN ADLSAVGGNIATIGGEFQALGFGRQFGGLPEAPPPEGDGEAPPPEGGAESERTRNQIDAFREVFGRDPAS DSDWLTASALDPHSYDPKNQGVDANVVVARIEPVPGQGVVRTNLFIPSEDVWAPTFDWPPYDNNLGDNRG FSPTAGPEASRVAIYTDFDNGIVVARQNPSINADTGQVRTGTPSIGAVQTSDGGVLIRYNAADPFSPGGE GLAKGSGISVNGTLGIVPSDTGPRVGGDDVTTFPALEVYSDRGGTTTTVLQQWPTFFDNAAGPLTGLPFD KDVGDPTVVPGFNSVVPQLVPPAIPGVGEPAPMPVTPPMSIVPPGNFTPFGPAGDAPTVRVYTPLQGTEF LPGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1151 | - | - | 100% (495) | hypothetical protein Mvan_1151 |
| M. vanbaalenii PYR-1 | Mvan_0088 | - | 1e-58 | 37.44% (454) | hypothetical protein Mvan_0088 |
| M. vanbaalenii PYR-1 | Mvan_4060 | - | 2e-41 | 44.74% (190) | hypothetical protein Mvan_4060 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 4e-05 | 29.55% (88) | hypothetical protein Mb3894 |
| M. gilvum PYR-GCK | Mflv_1605 | - | 5e-40 | 46.58% (161) | hypothetical protein Mflv_1605 |
| M. tuberculosis H37Rv | Rv3864 | - | 4e-05 | 29.55% (88) | hypothetical protein Rv3864 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4166 | espA | 2e-07 | 29.80% (151) | ESX-1 secretion-associated protein A, EspA |
| M. avium 104 | MAV_5295 | - | 4e-25 | 45.60% (125) | hypothetical protein MAV_5295 |
| M. smegmatis MC2 155 | MSMEG_5089 | - | 4e-32 | 36.46% (181) | hypothetical protein MSMEG_5089 |
| M. thermoresistible (build 8) | TH_3234 | - | 7e-45 | 44.50% (218) | PUTATIVE putative hypothetical protein Mvan_4060 |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1151|M.vanbaalenii_PYR-1 ---MGVLEAFLSTWS----KARATFGAGTPEPGSSYDE-SATLTGLSRDL
Mb3894|M.bovis_AF2122/97 ---MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKM
Rv3864|M.tuberculosis_H37Rv ---MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKM
Mflv_1605|M.gilvum_PYR-GCK ---MSVLGSFLTTWS----QARATFGDGVPLPGSTFDG-SSTLRRLEAET
TH_3234|M.thermoresistible__bu ---VSALAAFLTTWS----AARATFGEGTPRTGERFDH-SALFHRLQAEA
MSMEG_5089|M.smegmatis_MC2_155 ---MGALDGFYSTWN----KARETFGQGAPTDGSQFDQ-SRSLTQMKASV
MMAR_4166|M.marinum_M ---MSRAFIIDPTISAIN-GLHALLGIGLPEDGGIIDSALSFFGKALDDL
MAV_5295|M.avium_104 MFAGGDPWKINATLQSGRPAQISNLAKAFHDAGRSTGEAEAAFNLARGRF
. : * . :. . * . :
Mvan_1151|M.vanbaalenii_PYR-1 DEAAPTAHWSG--GAAEAYGTANADHRRVVGELGLLDRRLADQIDRSAQI
Mb3894|M.bovis_AF2122/97 GLAIPGTNWIG--QAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKY
Rv3864|M.tuberculosis_H37Rv GLAIPGTNWIG--QAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKY
Mflv_1605|M.gilvum_PYR-GCK RRAAPRSDWTG--GAADTYAAGNAEHARALARMAELDERMGREVDRSAVV
TH_3234|M.thermoresistible__bu QTAAPGDVWTG--TAADAYGAVNSEMIGVLGGLAALDVRLRAQVDSAAEV
MSMEG_5089|M.smegmatis_MC2_155 EAAAPDDRWQG--SGANAYAAANKEHAQVYQKLADLDQKMAAEVKNAANV
MMAR_4166|M.marinum_M GSAFPGDGWLG--SAADHYSGKNRKHVNFFKELAELDRELQKLIADQASA
MAV_5295|M.avium_104 EQAWTHENDENPINGSAEVQRTTTSLGVQAAQLPKIGADLEKVAAALAEA
* . . .: . : :. *
Mvan_1151|M.vanbaalenii_PYR-1 VTAGRQDLEAIREWVV------AAAASVPRN---RAG--ELMVAPIVRQG
Mb3894|M.bovis_AF2122/97 VSDTRDVLRAMKKMIDGVYKVCKGLEKIPLL---GHLWSWELAIPMSGIA
Rv3864|M.tuberculosis_H37Rv VSDTRDVLRAMKKMIDGVYKVCKGLEKIPLL---GHLWSWELAIPMSGIA
Mflv_1605|M.gilvum_PYR-GCK VRDGRVHLDSVKDWVL------SAAASVPDN---AAG--ERMLLPIVGKG
TH_3234|M.thermoresistible__bu VSAGRRDLESIRQAVT------TAAAALPTG---TVG--ERMLWPIVAQG
MSMEG_5089|M.smegmatis_MC2_155 VSAGRTNLDNAKSWVE------GMANSLPAT---SQQDRERKLIPIAREG
MMAR_4166|M.marinum_M VKTTREILEDAKKGLEFVRPVAVDLTYIPIV---GWAMSAAFQAPVCAAA
MAV_5295|M.avium_104 QRSGRGEISSLEGALQDLDDQVGEAVELEKNPQLTASERQLLDHYIDGLE
* : . : : :
Mvan_1151|M.vanbaalenii_PYR-1 LSQLAEVVTRANADLSAVGGNIATIGGEFQALGFGRQFGGLPEAPPPEGD
Mb3894|M.bovis_AF2122/97 MAVVGGALLYLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPD
Rv3864|M.tuberculosis_H37Rv MAVVGGALLYLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPD
Mflv_1605|M.gilvum_PYR-GCK CTDIADIVTSSNGQLATIAERIRSLGVEYAALDD----------AASVTP
TH_3234|M.thermoresistible__bu LGEITGIVRRSSGDLSQIGAELTRIGEEYRQLSEQKFGGGLPEQPAGEAP
MSMEG_5089|M.smegmatis_MC2_155 INRVDNIVKSATADMMGIKGNVEKLRGEYDTIKTTMRFGPESEKKPGDKK
MMAR_4166|M.marinum_M MAVVGGALAYLVVKTLINSMKLVSLLAQLAKLLAEAVADVVSDVVDIIKG
MAV_5295|M.avium_104 KHAIDDTKASVANLTRIRDQYSQQLHTSMANLREQDGYDPPIQAFDGDVP
: : :
Mvan_1151|M.vanbaalenii_PYR-1 GEAPPPEGGAESERTRNQIDAFREVFGRDPASDSDWLTASALDPHSYDPK
Mb3894|M.bovis_AF2122/97 IIDGLWPPKLPDIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFPGF
Rv3864|M.tuberculosis_H37Rv IIDGLWPPKLPDIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFP--
Mflv_1605|M.gilvum_PYR-GCK -------RSE----------------------------------------
TH_3234|M.thermoresistible__bu -------GEEPEHEDEDPAEAERDRRLEEIMRDYQVGEDPDGVIEWKSGG
MSMEG_5089|M.smegmatis_MC2_155 DDAQMLGNEEKDDDGIPEMHAPSTEDQARMDVEQVLSEGDGGAAERVDEV
MMAR_4166|M.marinum_M ------ILEEVWEFLTHPFEFLKDLLNKLVSWASSLLSQWGSKLQSFFG-
MAV_5295|M.avium_104 ------ESPSQEQRRHNQIEAFKQVFGREPASAADWETAAALDSQTYDSK
Mvan_1151|M.vanbaalenii_PYR-1 NQGVDANVVVARIEPVPGQGVVRTNLFIPSEDVWAPTFDWPPYDNNLGDN
Mb3894|M.bovis_AF2122/97 PSLPGFPGLPGFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDL
Rv3864|M.tuberculosis_H37Rv ----------GFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDL
Mflv_1605|M.gilvum_PYR-GCK ------------ATT-------------------------SDLRRPTPRH
TH_3234|M.thermoresistible__bu LVGMLTGSKEMTATEGRMMDELGLFGQRDMQQIVEQAREEANKRFPPPEG
MSMEG_5089|M.smegmatis_MC2_155 LSSIKPGDELTPQQDAYLSEMQRQQKGMSVEDLRAAEQRLGDHKNVIADS
MMAR_4166|M.marinum_M -------------------------GIPGLSGMGGGLSQLTSFFSSAGAA
MAV_5295|M.avium_104 FNGAKSEIRVVRIRPVPGQGVVRVSQWIEQRDVRSFPPWKRDLGNNRGAN
Mvan_1151|M.vanbaalenii_PYR-1 RGFSPTAG----------PEASRVAIYTDFDNGIVVARQNPSINADTGQV
Mb3894|M.bovis_AF2122/97 GKLPTWT------------------ELAALPDFLGGFAGLPSLGFG----
Rv3864|M.tuberculosis_H37Rv GKLPTWT------------------ELAALPDFLGGFAGLPSLGFG----
Mflv_1605|M.gilvum_PYR-GCK R-------------------------------------------------
TH_3234|M.thermoresistible__bu REIDNHN--------------------DAFRHAYWNALMTQRFGD-----
MSMEG_5089|M.smegmatis_MC2_155 WQLMSNDDVEYSAGAGDDKKGAASQLPDSVQKALTNAGDTWPIGDGIGQL
MMAR_4166|M.marinum_M GSAGSVG-------------------AADSASLVSSAGLPGGLGLG----
MAV_5295|M.avium_104 PNFDPEDTKVR-----CADSPTRHRLWTSHRHPFCAPSAHR---------
Mvan_1151|M.vanbaalenii_PYR-1 RTG-----------------------------------------------
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 RYEGDLKAISEIVKDGNPGFQTGTELDRQLIVAADKAMDARDIPGGQILG
MMAR_4166|M.marinum_M --------------------------------------------------
MAV_5295|M.avium_104 --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 -------------------------------------------------T
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 RESTVQSLFEAVDDDHQIINDHLMGRNGVDVDDFLRDVNTTDWPDNGKAA
MMAR_4166|M.marinum_M --------------------------------------------------
MAV_5295|M.avium_104 --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 PSIGAVQTSDGGVLIRYNAADPFSPGGEGLAKGSGISVN-----------
Mb3894|M.bovis_AF2122/97 -NLLSFASLPTVGQVTATMGQLQQLVAAGGGPSQLASMG-----------
Rv3864|M.tuberculosis_H37Rv -NLLSFASLPTVGQVTATMGQLQQLVAAGGGPSQLASMG-----------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu EWAEKFATAHEGIPRNYAASEAMDLFNNEVGRN-----------------
MSMEG_5089|M.smegmatis_MC2_155 GYLFSWTNEASSGPEAHIAAEVADKYAGYIGEHRTDLMNFDGQTLGQRNP
MMAR_4166|M.marinum_M -GGSGFGSMPNVAQLRSAATRQDPRLTSEGPTRVSSEPVG----------
MAV_5295|M.avium_104 QCSSRLITKSGRLVMRSSAREPFFDAEAWRIATVSAPFVVQG--------
Mvan_1151|M.vanbaalenii_PYR-1 --------GTLGIVPSDTGPRVGGDDVTTFPALE---VYSDRGGTTTTVL
Mb3894|M.bovis_AF2122/97 ----------SQQAQLISSQAQQGGQQHATLVSD---KKEDEEGAAAGVA
Rv3864|M.tuberculosis_H37Rv ----------SQQAQLISSQAQQGGQQHATLVSD---KKEDEE----GVA
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu ----------LAVANPDASKDELADLVEQAVRNG---DTVVVRPDGQGLE
MSMEG_5089|M.smegmatis_MC2_155 ELVQQYAHGLVPFVDDMAGNNGSGGEFEIDTEKD---RRAGLMPNAKGVF
MMAR_4166|M.marinum_M ---------EHAQAASAQGGQGMGGMHPASAGSKGATSKKYSEGAAAGTE
MAV_5295|M.avium_104 ---------VLALLMLTLWLLGEGPFKTHSAYAGERAWMVTASLIASAVS
Mvan_1151|M.vanbaalenii_PYR-1 QQWPTFFDNAAGPLTGLPFDKDVGDPTVVPGFNSVVPQLVPPAIPGVGEP
Mb3894|M.bovis_AF2122/97 EAERAPIDAGTAASQRGQEGTVL---------------------------
Rv3864|M.tuberculosis_H37Rv EAERAPIDAGTAASQRGQEGTVL---------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu WSDRITPESTGDSSRSAPVDGQIPTPAGQPNPHGGYEIG-----------
MSMEG_5089|M.smegmatis_MC2_155 SVLNTDPTAATTINSAAISQAMIAETAFAENPNDPLAHSYLSSAATLRGL
MMAR_4166|M.marinum_M DAERAPVEVGVGAAARIAERRAG---------------------------
MAV_5295|M.avium_104 LSISVPLAWTPSSRRRGISLSLAGCSALVLVGGVLYAYLTMR--------
Mvan_1151|M.vanbaalenii_PYR-1 APMPVTPPMSIVPPGNFTPFGPAG----DAPTVRVYTPLQGTEFLPGR--
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 VDVGAHEAFQAFNENGYNAGVDETTWKKAGFDAAVTAFSTGSTFVPGVGV
MMAR_4166|M.marinum_M --------------------------------------------------
MAV_5295|M.avium_104 --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 VASPVISQVGSIFSNEFFENPPGPVERPLPQLSEPVATTTLLNAMLAANQ
MMAR_4166|M.marinum_M --------------------------------------------------
MAV_5295|M.avium_104 --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 PLDLPPGYVVGNEVVQPPGVSDHEFAATLNAEIGRQTVTVDGDGPDEIYA
MMAR_4166|M.marinum_M --------------------------------------------------
MAV_5295|M.avium_104 --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 ------------------------
Mb3894|M.bovis_AF2122/97 ------------------------
Rv3864|M.tuberculosis_H37Rv ------------------------
Mflv_1605|M.gilvum_PYR-GCK ------------------------
TH_3234|M.thermoresistible__bu ------------------------
MSMEG_5089|M.smegmatis_MC2_155 DQYNLIIQDPDIQAPPTATRSENK
MMAR_4166|M.marinum_M ------------------------
MAV_5295|M.avium_104 ------------------------