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MFAGGDPWKINATLQSGRPAQISNLAKAFHDAGRSTGEAEAAFNLARGRFEQAWTHENDENPINGSAEVQ RTTTSLGVQAAQLPKIGADLEKVAAALAEAQRSGRGEISSLEGALQDLDDQVGEAVELEKNPQLTASERQ LLDHYIDGLEKHAIDDTKASVANLTRIRDQYSQQLHTSMANLREQDGYDPPIQAFDGDVPESPSQEQRRH NQIEAFKQVFGREPASAADWETAAALDSQTYDSKFNGAKSEIRVVRIRPVPGQGVVRVSQWIEQRDVRSF PPWKRDLGNNRGANPNFDPEDTKVRCADSPTRHRLWTSHRHPFCAPSAHRQCSSRLITKSGRLVMRSSAR EPFFDAEAWRIATVSAPFVVQGVLALLMLTLWLLGEGPFKTHSAYAGERAWMVTASLIASAVSLSISVPL AWTPSSRRRGISLSLAGCSALVLVGGVLYAYLTMR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5295 | - | - | 100% (455) | hypothetical protein MAV_5295 |
| M. avium 104 | MAV_0031 | - | 3e-50 | 50.72% (207) | hypothetical protein MAV_0031 |
| M. avium 104 | MAV_1467 | - | 2e-48 | 53.51% (185) | hypothetical protein MAV_1467 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2105 | - | 3e-55 | 56.93% (202) | hypothetical protein Mb2105 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2079 | - | 4e-55 | 56.93% (202) | hypothetical protein Rv2079 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3061 | - | 1e-57 | 54.05% (222) | hypothetical protein MMAR_3061 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_5057 | - | 6e-49 | 50.98% (204) | hypothetical protein MUL_5057 |
| M. vanbaalenii PYR-1 | Mvan_1151 | - | 5e-25 | 45.60% (125) | hypothetical protein Mvan_1151 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2105|M.bovis_AF2122/97 MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRCTAE
Rv2079|M.tuberculosis_H37Rv MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRYTAE
MUL_5057|M.ulcerans_Agy99 MQPRYISNPLLIAEAGGGPWAINQSLQLGRPAQISDLATAFHDAGRSTTE
MAV_5295|M.avium_104 ------------MFAGGDPWKINATLQSGRPAQISNLAKAFHDAGRSTGE
MMAR_3061|M.marinum_M MQLRYIGIPLLIAEAGGDPWAIDQSLQAGRPAQISDLGAAFHAAGRCTAE
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------MGVLEAFLSTWSKARATFGAGTPE
* :: . * * * *
Mb2105|M.bovis_AF2122/97 ANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGV
Rv2079|M.tuberculosis_H37Rv ANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGV
MUL_5057|M.ulcerans_Agy99 ADTAFEQARRRFETSWNRENGAHPINDSPQVQGLTTSLRSQAARLPEIGL
MAV_5295|M.avium_104 AEAAFNLARGRFEQAWTHENDENPINGSAEVQRTTTSLGVQAAQLPKIGA
MMAR_3061|M.marinum_M ADAAFDQARRRFEEAWNRQNSERPINDSAEVQRVAQSLGAQSLELPKIGV
Mvan_1151|M.vanbaalenii_PYR-1 PGSSYDESATLTGLSRDLDEAAPTAHWSG---GAAEAYGTANADHRRVVG
. :::: : : :: . : * : : .:
Mb2105|M.bovis_AF2122/97 DLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAAE
Rv2079|M.tuberculosis_H37Rv DLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAAE
MUL_5057|M.ulcerans_Agy99 QLDNIAGGLAGAQRSATGQIVGLETQLCDIDSEIGEVLALEHGAQLTTAD
MAV_5295|M.avium_104 DLEKVAAALAEAQRSGRGEISSLEGALQDLDDQVGEAVELEKNPQLTASE
MMAR_3061|M.marinum_M DLENIAAALAEVQRSSSGKIAGLEGQLRQLDDEIGQAVMLERNHQLTAED
Mvan_1151|M.vanbaalenii_PYR-1 ELGLLDRRLADQIDRSAQIVTAGRQDLEAIREWVVAAAASVPRNRAGELM
:* : ** . : . * : . : . :
Mb2105|M.bovis_AF2122/97 RSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGYD
Rv2079|M.tuberculosis_H37Rv RSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGYD
MUL_5057|M.ulcerans_Agy99 RLALEAIVCALEDQAVGDTQSAVSQLHSIRAGYAGLLHQAPTSLSADGFD
MAV_5295|M.avium_104 RQLLDHYIDGLEKHAIDDTKASVANLTRIRDQYSQQLHTSMANLREQDGY
MMAR_3061|M.marinum_M KAALDAFMHACEDDAIRDTQAALAELNSIRDGYSNFLRTAEKSLAVDGLD
Mvan_1151|M.vanbaalenii_PYR-1 VAPIVRQGLSQLAEVVTRANADLSAVGGNIATIGGEFQALGFGRQFGGLP
: ..: : : :. : . :: .
Mb2105|M.bovis_AF2122/97 GAGLQGLDAPQSPVKL-EEPIQIPPPGTGAPEVHRWWTSLTSEERQRLIA
Rv2079|M.tuberculosis_H37Rv GAGLQGLDAPQSPVKP-EEPIQIPPPGTGAPEVHRWWTSLTSEERQRLIA
MUL_5057|M.ulcerans_Agy99 PAVIQALDAPQSPAEP-AEVIAIAAPTASAEEVKKWWDSLSPQQRGRLID
MAV_5295|M.avium_104 DPPIQAFDG-DVPESP-SQEQRRHNQIEAFKQVFGREPASAADWETAAAL
MMAR_3061|M.marinum_M PARIWGADNHEPESAE-QAEQDVHDALAGDQGAAGRVNAVLGSITPDQLA
Mvan_1151|M.vanbaalenii_PYR-1 EAPPPEGDGEAPPPEGGAESERTRNQIDAFREVFGRDPASDSDWLTASAL
. * . . : .
Mb2105|M.bovis_AF2122/97 EHPEQIGNLNGVPVSARSDAN---IAVMTRDLNRVRDIATRYRTSVDDVL
Rv2079|M.tuberculosis_H37Rv EHPEQIGNLNGVPVSARSDAN---IAVMTRDLNRVRDIATRYRTSVDDVL
MUL_5057|M.ulcerans_Agy99 EHPPELGNLNGINAITRDLVN---QAVMDDDITRVESVAMQRGVSADDIV
MAV_5295|M.avium_104 DSQTYDSKFNGAKSEIRVVRI---RPVPGQGVVRVSQWIEQR--------
MMAR_3061|M.marinum_M GKVPLTAEQASVLSQLQAQEHGMSVGALTATEQRLGAQRAMIADSWQLMS
Mvan_1151|M.vanbaalenii_PYR-1 DPHSYDPKNQGVDANVVVARI---EPVPGQGVVRTNLFIPSE-----DVW
: . . *
Mb2105|M.bovis_AF2122/97 GDPAKYGLSAGDITRYRNADETKKGLDHNARNDPRNPSPVYLFAYDPMAF
Rv2079|M.tuberculosis_H37Rv GDPAKYGLSAGDITRYRNADETKKGLDHNARNDPRNPSPVYLFAYDPMAF
MUL_5057|M.ulcerans_Agy99 NNPQKYGLSASDVTRYRNAIRTRDGLIYDREHATDDPRPVMLWAYDPLAF
MAV_5295|M.avium_104 -DVRSFPPWKRDLGNNRGANPNFDPEDTKVR-CADSPTRHRLWTSHRHPF
MMAR_3061|M.marinum_M NPNISFPKTPLTVGAKQGSDTVKGGVTQLPESVQQALNSPGVLFTHQMND
Mvan_1151|M.vanbaalenii_PYR-1 APTFDWPPYDNNLGDNRGFSPTAGPEASRVAIYTDFDNGIVVARQNPSIN
.: : :. : .
Mb2105|M.bovis_AF2122/97 GGKGRAAIAIGNPDTAKHTAVIVPGTSSSVKGGWLHDNHDDALNLFNQAK
Rv2079|M.tuberculosis_H37Rv GGKGRAAIAIGNPDTAKHTAVIVPGTSSSVKGGWLHDNHDDALNLFNQAK
MUL_5057|M.ulcerans_Agy99 NGEGKAAIAIGNPDYARNTAVIVPGAGSSVAQGWMSD-HDDATNLYDQAL
MAV_5295|M.avium_104 CAPS----------------------------------------------
MMAR_3061|M.marinum_M IAGVVKDGDRGFQTNTELDRAMIHKASVMMDTPIWHADPASQGQDVERDP
Mvan_1151|M.vanbaalenii_PYR-1 ADTGQVR-------------------------------------------
Mb2105|M.bovis_AF2122/97 AADPNNP-TAVIAWMGYDAPNDFTDPRIATPMLARIGGAALAEDVNGLWV
Rv2079|M.tuberculosis_H37Rv AADPNNP-TAVIAWMGYDAPNDFTDPRIATPMLARIGGAALAEDVNGLWV
MUL_5057|M.ulcerans_Agy99 AADPEHHYTAVIAWMGYDAPNGFSDVRVTEPGLARSGGALLANDVNGLWV
MAV_5295|M.avium_104 -----------------------AHRQCSSRLITKSGRLVMRSSAR----
MMAR_3061|M.marinum_M ALDPAVSNVLSAVSPDHQVVHDTITGADHDKFLKNITHHYWKDNGQGVGS
Mvan_1151|M.vanbaalenii_PYR-1 -----------------------TGTPSIGAVQTSDGGVLIRYNAADPFS
.
Mb2105|M.bovis_AF2122/97 THLGVG-QNVTVLGHSYGSTTVADAFALGGMHANDAVLLGCPGTDLAHSA
Rv2079|M.tuberculosis_H37Rv THLGVG-QNVTVLGHSYGSTTVADAFALGGMHANDAVLLGCPGTDLAHSA
MUL_5057|M.ulcerans_Agy99 THNSLTPQHVTVIGHSYGSTTVADAFAGSGMQANDAILIGCPGTDLARSA
MAV_5295|M.avium_104 --------EPFFDAEAWRIATVSAPFVVQGVLALLMLTLWLLGEGPFKTH
MMAR_3061|M.marinum_M LFSWTG-DPAVVQGPEEGIAADTAHAYSSYIGGYQQELLHLPGNHTLGQV
Mvan_1151|M.vanbaalenii_PYR-1 PGGEGLAKGSGISVN--GTLGIVPSDTGPRVGGDDVTTFPALEVYSDRGG
. : . :
Mb2105|M.bovis_AF2122/97 ASFHLDGGRVYVGAASTDPISMLGQLDSLSQYVNRGNL------------
Rv2079|M.tuberculosis_H37Rv ASFHLDGGRVYVGAASTDPISMLGQLDSLSQYVNRGNL------------
MUL_5057|M.ulcerans_Agy99 ADFHFDGGQVYVGSASTDPVSWIGESSGVPGELLKGKLR-----------
MAV_5295|M.avium_104 SAYAGERAWMVTASLIASAVSLS---------------------------
MMAR_3061|M.marinum_M NPNLVRDMAHGLGPYVNNIAETSGGLPGFGKPLDSETLSGALPVAKGVFS
Mvan_1151|M.vanbaalenii_PYR-1 TTTTVLQQWPTFFDNAAGPLTGLPFDKDVGDPTVVPGFN-----------
.
Mb2105|M.bovis_AF2122/97 ----------------AGQLQGLAVGLGTDPAGDGF-------GSVRFRA
Rv2079|M.tuberculosis_H37Rv ----------------AGQLQGLAVGLGTDPAGDGF-------GSVRFRA
MUL_5057|M.ulcerans_Agy99 ---------------EYGVPIPLDAGLGRDPAGDGF-------GSVRFHA
MAV_5295|M.avium_104 ----------------------ISVPLAWTPSSRRR-------GISLSLA
MMAR_3061|M.marinum_M VLSSDNEAAQYFNGQAYAQAVLHEGAFAADPTHSGYNQHLYDAATLRALV
Mvan_1151|M.vanbaalenii_PYR-1 ----------------------SVVPQLVPPAIPGV-------GEPAPMP
*: .
Mb2105|M.bovis_AF2122/97 EVPNSDGINPHDHSYYYHRGSEALRSMADIASGHGDALASDGMLAQPRHQ
Rv2079|M.tuberculosis_H37Rv EVPNSDGINPHDHSYYYHRGSEALRSMADIASGHGDALASDGMLAQPRHQ
MUL_5057|M.ulcerans_Agy99 EVPGSGTMDRHDHSHYYVMGSESLRSITDISSGHPDRLASDDLIAEGRRQ
MAV_5295|M.avium_104 GCSALVLVGGVLYAYLTMR-------------------------------
MMAR_3061|M.marinum_M DVGTHNAFQANEDNGYHQGVSEYQSKKSAYETGLQGLTAAGGFVPGVGRI
Mvan_1151|M.vanbaalenii_PYR-1 VTPPMSIVPPGNFTPFGPAGDAPTVRVYTPLQGTEFLPGR----------
.
Mb2105|M.bovis_AF2122/97 PGVEIDIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLHR---
Rv2079|M.tuberculosis_H37Rv PGVEIDIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLHR---
MUL_5057|M.ulcerans_Agy99 P-------HVG--PLRVPGVPAYIDPESDRPRDTVHDDHHYPAYQPPR--
MAV_5295|M.avium_104 --------------------------------------------------
MMAR_3061|M.marinum_M AGPTIGVLGQNLENGILGPAPTAPTENPIQPMSLGMTDQEILNAMLGTGH
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 --------------------------------------------------
Rv2079|M.tuberculosis_H37Rv --------------------------------------------------
MUL_5057|M.ulcerans_Agy99 --------------------------------------------------
MAV_5295|M.avium_104 --------------------------------------------------
MMAR_3061|M.marinum_M TVTGLPPGYIVYDDDHPNGRIATLEELEPQGVTPGQYSNVIGPALSQSLE
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 --------------------------------
Rv2079|M.tuberculosis_H37Rv --------------------------------
MUL_5057|M.ulcerans_Agy99 --------------------------------
MAV_5295|M.avium_104 --------------------------------
MMAR_3061|M.marinum_M PRPPSESLSPDAALVSRYDDIVGVPHPDQGRK
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------