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SVLGSFLTTWSQARATFGDGVPLPGSTFDGSSTLRRLEAETRRAAPRSDWTGGAADTYAAGNAEHARALA RMAELDERMGREVDRSAVVVRDGRVHLDSVKDWVLSAAASVPDNAAGERMLLPIVGKGCTDIADIVTSSN GQLATIAERIRSLGVEYAALDDAASVTPRSEATTSDLRRPTPRHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1605 | - | - | 100% (186) | hypothetical protein Mflv_1605 |
| M. gilvum PYR-GCK | Mflv_0157 | - | 1e-10 | 27.43% (175) | hypothetical protein Mflv_0157 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 8e-07 | 30.21% (96) | hypothetical protein Mb3894 |
| M. tuberculosis H37Rv | Rv3864 | - | 8e-07 | 30.21% (96) | hypothetical protein Rv3864 |
| M. leprae Br4923 | MLBr_00405 | - | 3e-05 | 32.61% (92) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5431 | - | 2e-05 | 29.81% (104) | hypothetical protein MMAR_5431 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5089 | - | 4e-30 | 37.43% (179) | hypothetical protein MSMEG_5089 |
| M. thermoresistible (build 8) | TH_3234 | - | 6e-36 | 47.24% (163) | PUTATIVE putative hypothetical protein Mvan_4060 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1151 | - | 2e-40 | 46.58% (161) | hypothetical protein Mvan_1151 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1605|M.gilvum_PYR-GCK -------------------------------------------------M
TH_3234|M.thermoresistible__bu -------------------------------------------------V
Mvan_1151|M.vanbaalenii_PYR-1 -------------------------------------------------M
MSMEG_5089|M.smegmatis_MC2_155 -------------------------------------------------M
Mb3894|M.bovis_AF2122/97 -------------------------------------------------M
Rv3864|M.tuberculosis_H37Rv -------------------------------------------------M
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MMAR_5431|M.marinum_M MYLSQLQRLVQQISRWVRGDGNLQNFQDIQEGGGNPPPAQEGAPDNSPWA
Mflv_1605|M.gilvum_PYR-GCK SVLGSFLTTWS----QARATFGDGVPLPGSTFDG-SSTLRRLEAETRRAA
TH_3234|M.thermoresistible__bu SALAAFLTTWS----AARATFGEGTPRTGERFDH-SALFHRLQAEAQTAA
Mvan_1151|M.vanbaalenii_PYR-1 GVLEAFLSTWS----KARATFGAGTPEPGSSYDE-SATLTGLSRDLDEAA
MSMEG_5089|M.smegmatis_MC2_155 GALDGFYSTWN----KARETFGQGAPTDGSQFDQ-SRSLTQMKASVEAAA
Mb3894|M.bovis_AF2122/97 ASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLAI
Rv3864|M.tuberculosis_H37Rv ASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLAI
MLBr_00405|M.leprae_Br4923 MSGAFIIDPTLKAIEAWHALLGIGVPNDGGVLYSSLSFFEKALEHLAAAF
MMAR_5431|M.marinum_M RRGSVVCGVTEGILGLLLALLGEAVPSRGESLDRSGSMFDGVSTQIATLD
. :* . * * :
Mflv_1605|M.gilvum_PYR-GCK PRSDWTGGAADTYAAGNAEHARALARMAELDERMGREVDRSAVVVRDGRV
TH_3234|M.thermoresistible__bu PGDVWTGTAADAYGAVNSEMIGVLGGLAALDVRLRAQVDSAAEVVSAGRR
Mvan_1151|M.vanbaalenii_PYR-1 PTAHWSGGAAEAYGTANADHRRVVGELGLLDRRLADQIDRSAQIVTAGRQ
MSMEG_5089|M.smegmatis_MC2_155 PDDRWQGSGANAYAAANKEHAQVYQKLADLDQKMAAEVKNAANVVSAGRT
Mb3894|M.bovis_AF2122/97 PGTNWIGQAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTRD
Rv3864|M.tuberculosis_H37Rv PGTNWIGQAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTRD
MLBr_00405|M.leprae_Br4923 PGDGWLGSAADKYAGQNRKRVDIFQELAELDKELIELIHNQANSVQTTRG
MMAR_5431|M.marinum_M PDGGWRGNAARAYGAKNLAQSQHTTLIADLDRLTGELVSSQADAVKRARD
* * * .* * * :. ** : * * *
Mflv_1605|M.gilvum_PYR-GCK HLDSVKDWVLSAAASVP-------------DNAAG--ERMLLPIVGKGCT
TH_3234|M.thermoresistible__bu DLESIRQAVTTAAAALP-------------TGTVG--ERMLWPIVAQGLG
Mvan_1151|M.vanbaalenii_PYR-1 DLEAIREWVVAAAASVP-------------RNRAG--ELMVAPIVRQGLS
MSMEG_5089|M.smegmatis_MC2_155 NLDNAKSWVEGMANSLP-------------ATSQQDRERKLIPIAREGIN
Mb3894|M.bovis_AF2122/97 VLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWELAIPMSGIAMAVVGGALL
Rv3864|M.tuberculosis_H37Rv VLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWELAIPMSGIAMAVVGGALL
MLBr_00405|M.leprae_Br4923 ILDGAKKALLFVRPVAIDLNYIPLVGSVMSASIQAQACAAAMAAVSGGLA
MMAR_5431|M.marinum_M LLSAEIWIVLVLLVVCIGLELHGPEGQILSFHIAIPICTMAVFTAATALG
* : . .
Mflv_1605|M.gilvum_PYR-GCK DIADIVTSSNGQLATIAERIRSLGVEYAALDD----------AASVTPRS
TH_3234|M.thermoresistible__bu EITGIVRRSSGDLSQIGAELTRIGEEYRQLSEQKFGGGLPEQPAGEAPGE
Mvan_1151|M.vanbaalenii_PYR-1 QLAEVVTRANADLSAVGGNIATIGGEFQALGFGRQFGGLPEAPPPEGDGE
MSMEG_5089|M.smegmatis_MC2_155 RVDNIVKSATADMMGIKGNVEKLRGEYDTIKTTMRFGPESEKKPGDKKDD
Mb3894|M.bovis_AF2122/97 YLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWPPK
Rv3864|M.tuberculosis_H37Rv YLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWPPK
MLBr_00405|M.leprae_Br4923 YLLVQTAIHTAKFVALLARLAHLLASAVADVVSDGVAIIKGIVDHLWHFI
MMAR_5431|M.marinum_M VLAATTSQNASAVQAATQRLTAMAAALTTGADTVPSSPKMTFPPIHSLSE
: . . .: :
Mflv_1605|M.gilvum_PYR-GCK E-------------------------------------------------
TH_3234|M.thermoresistible__bu EPEHEDEDPAEAER--DRRLEEIMRDYQVGEDPDGVIEWKSGGLVGMLTG
Mvan_1151|M.vanbaalenii_PYR-1 APPPEGGAESERTRNQIDAFREVFGRDPASDSDWLTASALDPHSYDPKNQ
MSMEG_5089|M.smegmatis_MC2_155 AQMLGNEEKDDDGIPEMHAPSTEDQARMDVEQVLSEGDGGAAERVDEVLS
Mb3894|M.bovis_AF2122/97 LPDIPIPGLPDIPG--------------------------LPDFKWPPTP
Rv3864|M.tuberculosis_H37Rv LPDIPIPGLPDIPG--------------------------LPDFKWPPTP
MLBr_00405|M.leprae_Br4923 AGALTGLKDIVEKI-----------------------------IHWFFGL
MMAR_5431|M.marinum_M FDLTEATGPTPPQLP-----------------------------------
Mflv_1605|M.gilvum_PYR-GCK -----ATT-------------------------SDLRRPTPRHR------
TH_3234|M.thermoresistible__bu SKEMTATEGRMMDELGLFGQRDMQQIVEQAREEANKRFPPPEGREIDN--
Mvan_1151|M.vanbaalenii_PYR-1 GVDANVVVARIEPVPGQGVVRTNLFIPSEDVWAPTFDWPPYDNNLGDNRG
MSMEG_5089|M.smegmatis_MC2_155 SIKPGDELTPQQDAYLSEMQRQQKGMSVEDLRAAEQRLGDHKNVIADSWQ
Mb3894|M.bovis_AF2122/97 GSPLFPDLPSFPGFPGFPSLPGFPGLPGFPEFPAIPGFPALPG-------
Rv3864|M.tuberculosis_H37Rv GSPLFPDLPSFPGFP------------GFPEFPAIPGFPALPG-------
MLBr_00405|M.leprae_Br4923 FSHWWSRLHSFFGGIP-------------GLSGATSGLSQVTG-------
MMAR_5431|M.marinum_M --DLQSTLAELPG-------------------APEFHLATRAG-------
.
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu -----HNDAFR----------HAYWNALMT-----------------QRF
Mvan_1151|M.vanbaalenii_PYR-1 FSPTAGPEASR----------VAIYTDFDNGIVVARQNPSINADTGQVRT
MSMEG_5089|M.smegmatis_MC2_155 LMSNDDVEYSAGAGDDKKGAASQLPDSVQKALTNAGDTWPIGDGIGQLRY
Mb3894|M.bovis_AF2122/97 --LPSIPNLFPG----------------------------------LPGL
Rv3864|M.tuberculosis_H37Rv --LPSIPNLFPG----------------------------------LPGL
MLBr_00405|M.leprae_Br4923 ----------------------------------------LFGVPGLAGS
MMAR_5431|M.marinum_M --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu GDEWAEKFATAHEGIP----------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 GTPSIGAVQTSDGGVL----------------------------------
MSMEG_5089|M.smegmatis_MC2_155 EGDLKAISEIVKDGNPGFQTGTELDRQLIVAADKAMDARDIPGGQILGRE
Mb3894|M.bovis_AF2122/97 GDLLPGVGDLG---------------------------------------
Rv3864|M.tuberculosis_H37Rv GDLLPGVGDLG---------------------------------------
MLBr_00405|M.leprae_Br4923 SGLLSGE-------------------------------------------
MMAR_5431|M.marinum_M --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu -----RNYAASEAMDLFNNEVGRNLAVAN------------PDASKDE--
Mvan_1151|M.vanbaalenii_PYR-1 -----IRYNAADPFSPGGEGLAKGSGISVNGTLGIVPSDTGPRVGGDD--
MSMEG_5089|M.smegmatis_MC2_155 STVQSLFEAVDDDHQIINDHLMGRNGVDVDDFLRDVNTTDWPDNGKAAGY
Mb3894|M.bovis_AF2122/97 ------KLPTWTELAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVT--
Rv3864|M.tuberculosis_H37Rv ------KLPTWTELAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVT--
MLBr_00405|M.leprae_Br4923 ------SLLSTENLPSLAG-VGAGLGLGSLPQLAQLHAASTRQGTRSQAG
MMAR_5431|M.marinum_M --------AGFPDFGAPQLPITELTGLPTLPDPTNLTDPTSMLADLPT--
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu -------------------------------------LADLVEQAVRN--
Mvan_1151|M.vanbaalenii_PYR-1 -------------------------------------VTTFPALEVYSDR
MSMEG_5089|M.smegmatis_MC2_155 LFSWTNEASSGPEAHIAAEVADKYAGYIGEHRTDLMNFDGQTLGQRNPEL
Mb3894|M.bovis_AF2122/97 ------------------------------------ATMGQLQQLVAAG-
Rv3864|M.tuberculosis_H37Rv ------------------------------------ATMGQLQQLVAAG-
MLBr_00405|M.leprae_Br4923 -------------------------------------VSAELSTEQFGG-
MMAR_5431|M.marinum_M --------------------------------------IAQLSTTLSQL-
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu -------------------------------GDTVVVRPDGQGLEWSDRI
Mvan_1151|M.vanbaalenii_PYR-1 GGTTTTVLQQWPTFFDNAAGPLTGLPFDKDVGDPTVVPGFNSVVPQLVPP
MSMEG_5089|M.smegmatis_MC2_155 VQQYAHGLVPFVDDMAGNNGSGGEFEIDTEKDRRAGLMPNAKGVFSVLNT
Mb3894|M.bovis_AF2122/97 -------------------------------GGPSQLASMGSQQAQLISS
Rv3864|M.tuberculosis_H37Rv -------------------------------GGPSQLASMGSQQAQLISS
MLBr_00405|M.leprae_Br4923 ------------------------------QQEPVSAQGSQGMGGSQGMG
MMAR_5431|M.marinum_M ----------------------------------TNLAGPTSATTQPAQQ
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu TPESTGDSSRSAPVDGQIPTPAGQPNPHGGYEIG----------------
Mvan_1151|M.vanbaalenii_PYR-1 AIPGVGEPAPMPVTPPMSIVPPGNFTPFGPAGDAPTVRVYTPLQGTEFLP
MSMEG_5089|M.smegmatis_MC2_155 DPTAATTINSAAISQAMIAETAFAENPNDPLAHSYLSSAATLRGLVDVGA
Mb3894|M.bovis_AF2122/97 QAQQGGQQHATLVSDKKEDEEGAAAGVAEAERAPIDAGTAASQRGQEGTV
Rv3864|M.tuberculosis_H37Rv QAQQGGQQHATLVSDKKEDEE----GVAEAERAPIDAGTAASQRGQEGTV
MLBr_00405|M.leprae_Br4923 GMTPASTKSKKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHV
MMAR_5431|M.marinum_M HTTPADHRTQDDATN-TPDTATATAATSSSERAPLDTQTHPHRQRLLT--
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 GR------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 HEAFQAFNENGYNAGVDETTWKKAGFDAAVTAFSTGSTFVPGVGVVASPV
Mb3894|M.bovis_AF2122/97 L-------------------------------------------------
Rv3864|M.tuberculosis_H37Rv L-------------------------------------------------
MLBr_00405|M.leprae_Br4923 V-------------------------------------------------
MMAR_5431|M.marinum_M --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 ISQVGSIFSNEFFENPPGPVERPLPQLSEPVATTTLLNAMLAANQPLDLP
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MMAR_5431|M.marinum_M --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK --------------------------------------------------
TH_3234|M.thermoresistible__bu --------------------------------------------------
Mvan_1151|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5089|M.smegmatis_MC2_155 PGYVVGNEVVQPPGVSDHEFAATLNAEIGRQTVTVDGDGPDEIYADQYNL
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MMAR_5431|M.marinum_M --------------------------------------------------
Mflv_1605|M.gilvum_PYR-GCK -------------------
TH_3234|M.thermoresistible__bu -------------------
Mvan_1151|M.vanbaalenii_PYR-1 -------------------
MSMEG_5089|M.smegmatis_MC2_155 IIQDPDIQAPPTATRSENK
Mb3894|M.bovis_AF2122/97 -------------------
Rv3864|M.tuberculosis_H37Rv -------------------
MLBr_00405|M.leprae_Br4923 -------------------
MMAR_5431|M.marinum_M -------------------