For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTASSIRWVLVDGATGEESVTIDRGSVPVDDAFQADALLDRLLGRPVHAIGLTWTVEAERTASAVWQGLT DRGVENVIAVSDVESAEALACGIADLAGCERVVVGLAEPGTSVIAAVTPDGVTADRVDPAALTDVDGFDP DAIFVLGSGDVAGVVSALEQRSTVPVVSADEADLALARGAALASASAVSILDAQAAPARRRLSPTATLAS VLATAVVTFVVSLSVALGMTLTPDSPAPQMARAVTEPTPEPVEKPVVKPAPVKAAPPEPEAAPPPPAAPP VAEPVAVEIPAPAAPALPEAPPPVYDEPLAPPPVVAPAPAYVPPPPPANYLPPAPAAPAYVPPAQVPAYV PPAQQPAYVPPAPQQPRLRDRIIERIPIINRFHEPEY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1015 | - | - | 100% (387) | hypothetical protein Mvan_1015 |
| M. vanbaalenii PYR-1 | Mvan_3021 | - | 2e-47 | 36.78% (416) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0590 | - | 3e-32 | 28.15% (437) | hypothetical protein Mvan_0590 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1919 | - | 5e-29 | 31.73% (353) | hypothetical protein Mb1919 |
| M. gilvum PYR-GCK | Mflv_5241 | - | 1e-162 | 77.12% (389) | hypothetical protein Mflv_5241 |
| M. tuberculosis H37Rv | Rv1887 | - | 5e-29 | 31.73% (353) | hypothetical protein Rv1887 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 2e-09 | 40.74% (81) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_4296c | - | 2e-28 | 29.65% (452) | hypothetical protein MAB_4296c |
| M. marinum M | MMAR_2779 | - | 8e-31 | 31.02% (361) | hypothetical protein MMAR_2779 |
| M. avium 104 | MAV_4824 | - | 9e-31 | 31.74% (438) | hypothetical protein MAV_4824 |
| M. smegmatis MC2 155 | MSMEG_1195 | - | 2e-72 | 44.87% (419) | hypothetical protein MSMEG_1195 |
| M. thermoresistible (build 8) | TH_3639 | - | 3e-38 | 38.38% (297) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2968 | - | 1e-31 | 31.30% (361) | hypothetical protein MUL_2968 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1015|M.vanbaalenii_PYR-1 -------------MTASSIRWVLVDGATGE----ESVTIDRGSVPVDDA-
Mflv_5241|M.gilvum_PYR-GCK -----MDLVLGLSMTSSSVRWVVVDGAAGE----ESRTIDRGSTPVDDG-
MSMEG_1195|M.smegmatis_MC2_155 -----MDLVLGLAMTSRAIRWVLVEGTTG-----AGDAIDRGAIAVDDAA
TH_3639|M.thermoresistible__bu -----MDFVLGLSVTSAGTRAVLVEGAAG-----DGATLDQFSSATTDDL
Mb1919|M.bovis_AF2122/97 -----MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAI
Rv1887|M.tuberculosis_H37Rv -----MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAI
MMAR_2779|M.marinum_M -----MDTVLGLSVTPTTVGWVLAEGHGADGAILDHHESQLHGSRGMRIV
MUL_2968|M.ulcerans_Agy99 MRCEVLDTVLGLSVTPTTVGWVLAEGHGADGAILDHHESQLHGSRGMRIV
MAB_4296c|M.abscessus_ATCC_199 -----MDVVLGVSMTPTTARLVLVEGAGADGRIVDTDTIVVSEGEG----
MAV_4824|M.avium_104 -----MDTVLGVSMAPTAVRMVLVEGENGDGATVDEDNFDVATSEDAATV
MLBr_02395|M.leprae_Br4923 ---------MTDQPPPSGSNPTPAPPPPG-----SSGGYEPSFAPSELGS
.. . . .
Mvan_1015|M.vanbaalenii_PYR-1 -FQADA--LLDRLLG------RPVHAIGLTWTVEAERTASAVWQGLTDRG
Mflv_5241|M.gilvum_PYR-GCK -FDARA--LVDRLLQ------HSVHAVGLNWDITAESTVSAVWQAFTDRG
MSMEG_1195|M.smegmatis_MC2_155 AYEPDG--LLRGLVDDTVVQGHRIHAIGVTWTCDASVLATRVMGALESWG
TH_3639|M.thermoresistible__bu VLALSENPTFGPALN-AAASGDGISTIGVTCSHDATTAAGLVVDDLLARG
Mb1919|M.bovis_AF2122/97 HTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAG
Rv1887|M.tuberculosis_H37Rv HTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAG
MMAR_2779|M.marinum_M HTAEQVADEVWHAKEVASGAGHRLRMIGVTWGDEASAQAALLLEALTDAG
MUL_2968|M.ulcerans_Agy99 HTAEQVADEVWHAKEVASGAGHRLRMIGVTWSDEASAQAALLLEALTDAG
MAB_4296c|M.abscessus_ATCC_199 TTSEQVLSAIVGTRDGMLDGGHNLVSTGVVWS--DHAEAAELRDSLASRG
MAV_4824|M.avium_104 TASDQVLSAILGTRQGAAEGGYQLASTGVTFT--DPVEAAALRDKLAAHK
MLBr_02395|M.leprae_Br4923 AYPPPTAPPVGGSYP-------PPPPPGGSYPPPPPPGGSYPPPPPSTG-
. *
Mvan_1015|M.vanbaalenii_PYR-1 VENVIAVSDVESAEALACGIADLAGCERVVVGLAEPGTSVIAAVTPDGVT
Mflv_5241|M.gilvum_PYR-GCK VENVFAVSDVEAAEALARGIADIAGCERLVVCVAEPGPSVLAAVTPHGVT
MSMEG_1195|M.smegmatis_MC2_155 HTNVIAVSEVEAAGILASGIAELTGHDDIAVCIIESDAAVAATVTADAVS
TH_3639|M.thermoresistible__bu CRNVVSVSELDAAEALATGLADLAGYTEIAVCIAEPDDAVIAVVGADDVV
Mb1919|M.bovis_AF2122/97 FDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDTHDGK
Rv1887|M.tuberculosis_H37Rv FDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDTHDGK
MMAR_2779|M.marinum_M FDNVVPVRLLDAVETLAEAIAPVIGYDQTAVCILEHDWATVVMVDTQDGK
MUL_2968|M.ulcerans_Agy99 FDNVVPVRLVDAVETLAEAIAPVIGYDQTAVCILEHDWATVVMVDTQDGK
MAB_4296c|M.abscessus_ATCC_199 IDGVEFFSALHAGGALAKAASSVTGYDKSALLVIEPQTATLAVVDSADGS
MAV_4824|M.avium_104 VENVMLVSAFLAAAALAQAVGHRTNYAHTALLYIEPDTATLAVVDSADGS
MLBr_02395|M.leprae_Br4923 -----AYAPPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIGML
. : : . :
Mvan_1015|M.vanbaalenii_PYR-1 ADRVDP---------------AALTDVDGFD--PDAIFVLGSG-DVAGVV
Mflv_5241|M.gilvum_PYR-GCK ADRVDP---------------SALTDVEALA--PDAVFVLGSG-DVAPVV
MSMEG_1195|M.smegmatis_MC2_155 ADRIARSPGDDDSVELIESLKAVLEESTGGR--TEGIFLLGSE-CDDLIV
TH_3639|M.thermoresistible__bu LDGIGRAAAPAPEN--IADHLLTTLGDTAAT--PQAVFVVGSAPDVGDVA
Mb1919|M.bovis_AF2122/97 TQIAVKHVCRGLSG--LTSWLTGMFGRDAWR--PAGVVVVGSDSEVSEFS
Rv1887|M.tuberculosis_H37Rv TQIAVKHVCRGLSG--LTSWLTGMFGRDAWR--PAGVVVVGSDSEVSEFS
MMAR_2779|M.marinum_M TQTAVKHVRGGFDG--LNSWLTGMFDRGAWR--PAAVVVVGSDTDVEEFS
MUL_2968|M.ulcerans_Agy99 TQTAVKHVRGGFDG--LNSWLTGMFDRGAWR--PAAVVVVGSDTDVEEFS
MAB_4296c|M.abscessus_ATCC_199 IVGLASEPLITG--VTSGVLANLVNPLKGKENAPDGVFLLGLGTDVSDLA
MAV_4824|M.avium_104 IADVRRQPLPEDDEAAVAELASMVSNAENLETRPDAVFVVGSGIDIPLIK
MLBr_02395|M.leprae_Br4923 IQTLTKQ-------------EACVTDITQYN---VNQYCATQPTGIGMLA
.
Mvan_1015|M.vanbaalenii_PYR-1 SALEQRSTVPVVSADEADLALARGAALASASAVSILDA--------QAAP
Mflv_5241|M.gilvum_PYR-GCK AELEQRLQAPVVSAEEADLALARGAALASASAVSILDA--------QDAP
MSMEG_1195|M.smegmatis_MC2_155 ASLSEAATVPVVSSAEADLAYPRGAALS--AALAINTP--------SEEP
TH_3639|M.thermoresistible__bu AALEATLEVPVLSAQEGDLALARGAALASARSAAVAYP--------PARP
Mb1919|M.bovis_AF2122/97 WQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVSQPTV
Rv1887|M.tuberculosis_H37Rv WQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVSQPTV
MMAR_2779|M.marinum_M WQLEKALPVPVFAQTMAQVTIARGAALAAAQSTDFTDARLIAD-VSEPAP
MUL_2968|M.ulcerans_Agy99 WQLEKALPVPVFAQTMAQVTIARGAALAAAQSTDFTDARLIAD-VSEPAP
MAB_4296c|M.abscessus_ATCC_199 ESLGDAIALPVNSPDQPELALARGAALASAQEPDFEASTALLGQAYSLEG
MAV_4824|M.avium_104 PALEAATTLPLTAPEEPDTALARGAALASAHAPLFASSTAALAYAQDPGT
MLBr_02395|M.leprae_Br4923 FWFAWLMATAYLVWNYGYRQGATGSSIGKTVMKFKVIS------------
: . . *:::. .
Mvan_1015|M.vanbaalenii_PYR-1 ARRRLSPTAT----------------------------------------
Mflv_5241|M.gilvum_PYR-GCK ARRKLTPTAT----------------------------------------
MSMEG_1195|M.smegmatis_MC2_155 KGLHFTKVGA----------------------------------------
TH_3639|M.thermoresistible__bu --LRLTRVGV----------------------------------------
Mb1919|M.bovis_AF2122/97 APRRSRHYAG----------------------------------------
Rv1887|M.tuberculosis_H37Rv APRRSRHYAG----------------------------------------
MMAR_2779|M.marinum_M APKRSLHYAG----------------------------------------
MUL_2968|M.ulcerans_Agy99 APKRSLHYAG----------------------------------------
MAB_4296c|M.abscessus_ATCC_199 PTGTGFAHPDAVTESAGEANTELREFEDFDDQP-----------------
MAV_4824|M.avium_104 GAINPLAVAPGYFETPADAGADGLAYSAVPDDPDEFFTGTQAAATELVDA
MLBr_02395|M.leprae_Br4923 -EATGQPIG-----------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 -----LASVLATAVVTFVVSLSVALGMTLTPDSPAPQMARAVTEPTPEPV
Mflv_5241|M.gilvum_PYR-GCK -----LAGVLAAAVVTFVASLSVALGMTLTPDSPAPQMARAVTEPAPEPV
MSMEG_1195|M.smegmatis_MC2_155 -----LSSVLAAAVVTLVVASSAAVGIQLHPGAIAP-AAEVTDAGKSEPA
TH_3639|M.thermoresistible__bu -----LSSVLVAASLTFVVSLSLAL----TPQPASEQRATSPTAGDARPV
Mb1919|M.bovis_AF2122/97 -----AAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIA
Rv1887|M.tuberculosis_H37Rv -----AAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIA
MMAR_2779|M.marinum_M -----AATTLAAAAVTFVGSLSLAIGLQLTPERHHTATGHAGHKPTPEIV
MUL_2968|M.ulcerans_Agy99 -----AATTLAAAAVTFVGSLSLAIGLQLTPERHHTATGHAGHKPTPEIV
MAB_4296c|M.abscessus_ATCC_199 --AERKPFLLVGAPLLLVFGICSIALAVSLTVTVRSTVDQGPSSPDRGVV
MAV_4824|M.avium_104 DYADRSSFKLVGSAVAAIFVIGVVALVVSLAIAIRPTANVRPSPNQNVVV
MLBr_02395|M.leprae_Br4923 -----FGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADKIMTTVCLP
:. :
Mvan_1015|M.vanbaalenii_PYR-1 EKPV-VKPAPVKAAPPEPEAAPPPPA-APPVAEPVA-VEIPAPAAPALPE
Mflv_5241|M.gilvum_PYR-GCK TK-----PSPVKAAPKAPEAAPVPPP-PPPVAEPVA-VEMPMPEAPVVPE
MSMEG_1195|M.smegmatis_MC2_155 ASKP-ATPAAAPRPKPPAAPAPAPEA-RPPAPEPAAPAPAPAAPAPVAEV
TH_3639|M.thermoresistible__bu AX----------XXPARPARRPRPGG-SPPG-------------------
Mb1919|M.bovis_AF2122/97 KAVAPAVPPPPTVTPPVPARAPRPAAQHEPPARVTSGEALTEPNPPEEQP
Rv1887|M.tuberculosis_H37Rv KAVAPAVPPPPTVTPPVPARAPRPAAQHEPPARVTSGEALTEPNPPEEQP
MMAR_2779|M.marinum_M EAVAPVVPMPAQPEPSAPHQAPAPGAGQEP-IRLTAGEQITDAAPVE-QP
MUL_2968|M.ulcerans_Agy99 EAVAPVVPMPAQPEPSAPHQAPAPGAGQEP-IRLTAGEQITDAAPVE-QP
MAB_4296c|M.abscessus_ATCC_199 QNPLPAEAPKQAAPPPSPVEAPAPAVSPAPVQQVVAPAPQHNPAPAPKQV
MAV_4824|M.avium_104 APTRPAPAAPAPAPAP---EAPAPAPAAAP--QAPAPAPEA-PAPAPAAP
MLBr_02395|M.leprae_Br4923 I-------------------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 APPPVYDEP---LAPPPVVAPAPAYVPPPPPANYLPPAPAAPAYVPPAQV
Mflv_5241|M.gilvum_PYR-GCK APPPVYVEP---LAPAPYVPPAPAYVPPPPPANYLPPAP-------PPAA
MSMEG_1195|M.smegmatis_MC2_155 NSVPAAEPP---AYVPPAPAPEPAYVPPAPEPAYVPPPP-----------
TH_3639|M.thermoresistible__bu --------------------------------------------------
Mb1919|M.bovis_AF2122/97 NASAPQQDR---NDSQP-ITRVLEHIPGAYG--DSAPPAE----------
Rv1887|M.tuberculosis_H37Rv NASAPQQDR---NDSQP-ITRVLEHIPGAYG--DSAPPAE----------
MMAR_2779|M.marinum_M GGEAPQSEP---ADGSPMLTRVLTHIPGSYGEEEGSRPPE----------
MUL_2968|M.ulcerans_Agy99 GGEAPQSEP---ADGSPMLTRVLTHIPGSYGEEEGSRPPE----------
MAB_4296c|M.abscessus_ATCC_199 APAPVQAAPQAPAPAPEAPAPAAPAPVPEEQPAPVAPPPAVVPVPIPLFP
MAV_4824|M.avium_104 APAPVQVAP---VPVPEAPAPAPAAPPP--------PPPAVAPIPVPIP-
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 PAYVPPAQQPAYVPPAPQQPRLRDRIIERIPIINRFHEPEY---------
Mflv_5241|M.gilvum_PYR-GCK PPYVPPVQTPLIPQQPVPQPRLRDRIIERIPIINRFHEPPY---------
MSMEG_1195|M.smegmatis_MC2_155 PAFVPPPPPPPLN---YPQPRLRDRIIERIPIINRFHEPKPWG-------
TH_3639|M.thermoresistible__bu --------------------------------------------------
Mb1919|M.bovis_AF2122/97 --------------------------------------------------
Rv1887|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2779|M.marinum_M --------------------------------------------------
MUL_2968|M.ulcerans_Agy99 --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 PVWEPPRRQENPWWPDRDRPRYTPPAQTQQPPIISIPGLPPIGGGDSDRG
MAV_4824|M.avium_104 ---------------------------------LPIPGL-----------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5241|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1195|M.smegmatis_MC2_155 --------------------------------------------------
TH_3639|M.thermoresistible__bu --------------------------------------------------
Mb1919|M.bovis_AF2122/97 --------------------------------------------------
Rv1887|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2779|M.marinum_M --------------------------------------------------
MUL_2968|M.ulcerans_Agy99 --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 SHGGSRGGSGRGGWGDDGDSRGGSDSGSRGGWGDNGGSRGGWGDSGSSRG
MAV_4824|M.avium_104 ------GGPGFG--------------GPPGHGGGDGGGHGGGGFPGFPGG
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 ------------------------------------
Mflv_5241|M.gilvum_PYR-GCK ------------------------------------
MSMEG_1195|M.smegmatis_MC2_155 ------------------------------------
TH_3639|M.thermoresistible__bu ------------------------------------
Mb1919|M.bovis_AF2122/97 ------------------------------------
Rv1887|M.tuberculosis_H37Rv ------------------------------------
MMAR_2779|M.marinum_M ------------------------------------
MUL_2968|M.ulcerans_Agy99 ------------------------------------
MAB_4296c|M.abscessus_ATCC_199 GSDSGSRGGWGGNSGSHGGGSGGGSNSGFPWPFGGR
MAV_4824|M.avium_104 GGHGG--GGFPGFGGGHGG-------------FGHH
MLBr_02395|M.leprae_Br4923 ------------------------------------