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MDLVLGLAMTSRAIRWVLVEGTTGAGDAIDRGAIAVDDAAAYEPDGLLRGLVDDTVVQGHRIHAIGVTWT CDASVLATRVMGALESWGHTNVIAVSEVEAAGILASGIAELTGHDDIAVCIIESDAAVAATVTADAVSAD RIARSPGDDDSVELIESLKAVLEESTGGRTEGIFLLGSECDDLIVASLSEAATVPVVSSAEADLAYPRGA ALSAALAINTPSEEPKGLHFTKVGALSSVLAAAVVTLVVASSAAVGIQLHPGAIAPAAEVTDAGKSEPAA SKPATPAAAPRPKPPAAPAPAPEARPPAPEPAAPAPAPAAPAPVAEVNSVPAAEPPAYVPPAPAPEPAYV PPAPEPAYVPPPPPAFVPPPPPPPLNYPQPRLRDRIIERIPIINRFHEPKPWG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1195 | - | - | 100% (403) | hypothetical protein MSMEG_1195 |
| M. smegmatis MC2 155 | MSMEG_0679 | - | 2e-36 | 30.80% (461) | hypothetical protein MSMEG_0679 |
| M. smegmatis MC2 155 | MSMEG_3531 | - | 3e-33 | 29.98% (407) | hypothetical protein MSMEG_3531 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1919 | - | 1e-30 | 30.27% (403) | hypothetical protein Mb1919 |
| M. gilvum PYR-GCK | Mflv_5241 | - | 9e-72 | 43.20% (419) | hypothetical protein Mflv_5241 |
| M. tuberculosis H37Rv | Rv1887 | - | 1e-30 | 30.27% (403) | hypothetical protein Rv1887 |
| M. leprae Br4923 | MLBr_00048 | - | 4e-09 | 31.72% (145) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_4296c | - | 1e-34 | 32.05% (443) | hypothetical protein MAB_4296c |
| M. marinum M | MMAR_0602 | - | 7e-41 | 32.02% (456) | hypothetical protein MMAR_0602 |
| M. avium 104 | MAV_4824 | - | 1e-37 | 32.41% (432) | hypothetical protein MAV_4824 |
| M. thermoresistible (build 8) | TH_3639 | - | 3e-39 | 39.67% (300) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1227 | - | 3e-31 | 30.55% (455) | hypothetical protein MUL_1227 |
| M. vanbaalenii PYR-1 | Mvan_1015 | - | 2e-72 | 44.87% (419) | hypothetical protein Mvan_1015 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5241|M.gilvum_PYR-GCK -----------------------MDLVLGLSMTSSSVRWVVVDGAAGEES
Mvan_1015|M.vanbaalenii_PYR-1 -------------------------------MTASSIRWVLVDGATGEES
MSMEG_1195|M.smegmatis_MC2_155 -----------------------MDLVLGLAMTSRAIRWVLVEGTTG-AG
Mb1919|M.bovis_AF2122/97 -----------------------MDTVLGLSITPTTLGWVLAEGHGADGA
Rv1887|M.tuberculosis_H37Rv -----------------------MDTVLGLSITPTTLGWVLAEGHGADGA
TH_3639|M.thermoresistible__bu -----------------------MDFVLGLSVTSAGTRAVLVEGAAGDGA
MMAR_0602|M.marinum_M --------------MVEQVLGELLDTVLGVSVAPTAVRLVLVEGENGDGA
MAV_4824|M.avium_104 -----------------------MDTVLGVSMAPTAVRMVLVEGENGDGA
MUL_1227|M.ulcerans_Agy99 -----------------------MDIVLGVSMEPGAVRLVLVEGIDADGV
MAB_4296c|M.abscessus_ATCC_199 -----------------------MDVVLGVSMTPTTARLVLVEGAGADGR
MLBr_00048|M.leprae_Br4923 MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIPTCTTTPNGEVA
: . . . .
Mflv_5241|M.gilvum_PYR-GCK RTID------RGSTPVDDG--FDARALVDRLLQ------HSVHAVGLNWD
Mvan_1015|M.vanbaalenii_PYR-1 VTID------RGSVPVDDA--FQADALLDRLLG------RPVHAIGLTWT
MSMEG_1195|M.smegmatis_MC2_155 DAID------RGAIAVDDAAAYEPDGLLRGLVDDTVVQGHRIHAIGVTWT
Mb1919|M.bovis_AF2122/97 ILDRNELELHSGRNAQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWN
Rv1887|M.tuberculosis_H37Rv ILDRNELELHSGRNAQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWN
TH_3639|M.thermoresistible__bu TLDQ-----FSSATTDDLVLALSENPTFGPALNAAASGDG-ISTIGVTCS
MMAR_0602|M.marinum_M LVDEDAFDVSGDGDAATIGAAEQVISAILGTREGASEGGYQLTSTGVTWR
MAV_4824|M.avium_104 TVDEDNFDVATSEDAATVTASDQVLSAILGTRQGAAEGGYQLASTGVTFT
MUL_1227|M.ulcerans_Agy99 TVEEDTFELDTAD--RSQGAPAAAVAALIGTREGAIEGGYRLMSAGVTWT
MAB_4296c|M.abscessus_ATCC_199 IVDTDTIVVSEGE----GTTSEQVLSAIVGTRDGMLDGGHNLVSTGVVWS
MLBr_00048|M.leprae_Br4923 SPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPASSESPRAPMPVSAP
:
Mflv_5241|M.gilvum_PYR-GCK ITAESTVSAVWQAFTDRG--VENVFAVSDVEAAEALARGIADIAGCERLV
Mvan_1015|M.vanbaalenii_PYR-1 VEAERTASAVWQGLTDRG--VENVIAVSDVESAEALACGIADLAGCERVV
MSMEG_1195|M.smegmatis_MC2_155 CDASVLATRVMGALESWG--HTNVIAVSEVEAAGILASGIAELTGHDDIA
Mb1919|M.bovis_AF2122/97 AEASAQAALLVESLTGAG--FDNVVPVRRLRAIETLAQAIAPVIGYEQIA
Rv1887|M.tuberculosis_H37Rv AEASAQAALLVESLTGAG--FDNVVPVRRLRAIETLAQAIAPVIGYEQIA
TH_3639|M.thermoresistible__bu HDATTAAGLVVDDLLARG--CRNVVSVSELDAAEALATGLADLAGYTEIA
MMAR_0602|M.marinum_M --DPAQAAALRDVLARRK--IENVVLVSAFLAAAALAHAVGSETNYAQTA
MAV_4824|M.avium_104 --DPVEAAALRDKLAAHK--VENVMLVSAFLAAAALAQAVGHRTNYAHTA
MUL_1227|M.ulcerans_Agy99 --DPTDVAALRAELAGHD--VGSVMLVSPLLAAAALAQTVGCALDYEYIA
MAB_4296c|M.abscessus_ATCC_199 --DHAEAAELRDSLASRG--IDGVEFFSALHAGGALAKAASSVTGYDKSA
MLBr_00048|M.leprae_Br4923 PRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVPIPINEPSPAKPATP
. .
Mflv_5241|M.gilvum_PYR-GCK VCVAEPGPSVLAAVTPHGVTADRVDP---------------SALTDVEAL
Mvan_1015|M.vanbaalenii_PYR-1 VGLAEPGTSVIAAVTPDGVTADRVDP---------------AALTDVDGF
MSMEG_1195|M.smegmatis_MC2_155 VCIIESDAAVAATVTADAVSADRIARSPGDDDSVELIESLKAVLEESTGG
Mb1919|M.bovis_AF2122/97 VCVLEHESATVVMVDTHDGKTQIAVKHVCRGLSG--LTSWLTGMFGRDAW
Rv1887|M.tuberculosis_H37Rv VCVLEHESATVVMVDTHDGKTQIAVKHVCRGLSG--LTSWLTGMFGRDAW
TH_3639|M.thermoresistible__bu VCIAEPDDAVIAVVGADDVVLDGIGRAAAPAPEN--IADHLLTTLGDTAA
MMAR_0602|M.marinum_M LLFIEPEAATLAVVDSADGSVTDIHRLSLSDDDDTAVGQLTELISQAESL
MAV_4824|M.avium_104 LLYIEPDTATLAVVDSADGSIADVRRQPLPEDDEAAVAELASMVSNAENL
MUL_1227|M.ulcerans_Agy99 MLFVEADSATLAVVDIGDGSIVDLHRRSLG--AESTAADLTSLVGGLATA
MAB_4296c|M.abscessus_ATCC_199 LLVIEPQTATLAVVDSADGSIVGLASEPLIT--GVTSGVLANLVNPLKGK
MLBr_00048|M.leprae_Br4923 MPMTPIDGSQRTPVTSPEPSLAEFEAQPPATPKPSLLPRPMSSPPEAPRP
: : . *
Mflv_5241|M.gilvum_PYR-GCK A--PDAVFVLGSG-DVAPVVAELEQRLQAPVVSAEE--ADLALARGAALA
Mvan_1015|M.vanbaalenii_PYR-1 D--PDAIFVLGSG-DVAGVVSALEQRSTVPVVSADE--ADLALARGAALA
MSMEG_1195|M.smegmatis_MC2_155 R--TEGIFLLGSE-CDDLIVASLSEAATVPVVSSAE--ADLAYPRGAALS
Mb1919|M.bovis_AF2122/97 R--PAGVVVVGSDSEVSEFSWQLERVLPVPVFAQTM--AQVTVARGAALA
Rv1887|M.tuberculosis_H37Rv R--PAGVVVVGSDSEVSEFSWQLERVLPVPVFAQTM--AQVTVARGAALA
TH_3639|M.thermoresistible__bu T--PQAVFVVGSAPDVGDVAAALEATLEVPVLSAQE--GDLALARGAALA
MMAR_0602|M.marinum_M PTRPDAVFLVGSGIDLPLIKPTLEASTTLPVTAAEE--PDTALARGAALA
MAV_4824|M.avium_104 ETRPDAVFVVGSGIDIPLIKPALEAATTLPLTAPEE--PDTALARGAALA
MUL_1227|M.ulcerans_Agy99 QSVAEGVFVVGCGVDIVALKPVLEAATSLVVSVPEE--PDMALARRAALA
MAB_4296c|M.abscessus_ATCC_199 ENAPDGVFLLGLGTDVSDLAESLGDAIALPVNSPDQ--PELALARGAALA
MLBr_00048|M.leprae_Br4923 SANQHSRHARRGHHHRDETQQANPASATEPMIAPRARTAELRQAPHAAAE
. : : . **
Mflv_5241|M.gilvum_PYR-GCK SASAVSILDA----------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 SASAVSILDA----------------------------------------
MSMEG_1195|M.smegmatis_MC2_155 --AALAINTP----------------------------------------
Mb1919|M.bovis_AF2122/97 AAQSTEFTDAQLVADSVS--------------------------------
Rv1887|M.tuberculosis_H37Rv AAQSTEFTDAQLVADSVS--------------------------------
TH_3639|M.thermoresistible__bu SARS----------AAVA--------------------------------
MMAR_0602|M.marinum_M AASSPLFASSTAAQAWAQDPGSGVLY----------SHAPYGLDAAYFDD
MAV_4824|M.avium_104 SAHAPLFASSTAALAYAQDPGTGAINPLAVAPGYFETPADAGADGLAYSA
MUL_1227|M.ulcerans_Agy99 SANAPLFASSTSALAYALDPGTGEVN-------------PRALAPSYLDV
MAB_4296c|M.abscessus_ATCC_199 SAQEPDFEASTALLGQAYSLEG-----------------PTGTGFAHPDA
MLBr_00048|M.leprae_Br4923 PAPTQHLTRPDGLVSHRTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRG
Mflv_5241|M.gilvum_PYR-GCK -----------------------QDAPARRKLTPTATLAGVLAAAVVTFV
Mvan_1015|M.vanbaalenii_PYR-1 -----------------------QAAPARRRLSPTATLASVLATAVVTFV
MSMEG_1195|M.smegmatis_MC2_155 -----------------------SEEPKGLHFTKVGALSSVLAAAVVTLV
Mb1919|M.bovis_AF2122/97 -----------------------QPTVAPRRSRHYAGAAAALAAAAVTFV
Rv1887|M.tuberculosis_H37Rv -----------------------QPTVAPRRSRHYAGAAAALAAAAVTFV
TH_3639|M.thermoresistible__bu -----------------------YPPARPLRLTRVGVLSSVLVAASLTFV
MMAR_0602|M.marinum_M VS-DQLG---TGQQALAYSAVPEEQHERRPFALLASIMGSIFIIGVGALA
MAV_4824|M.avium_104 VP-DDPDEFFTGTQAAATELVDADYADRSSFKLVGSAVAAIFVIGVVALV
MUL_1227|M.ulcerans_Agy99 CANADRGAGSLAYSALADDGEDAVEGRRRPLVLAGSAMLGIAAFAAGLMV
MAB_4296c|M.abscessus_ATCC_199 VT-ESAG--EANTELREFEDFDDQPAERKPFLLVGAPLLLVFGICSIALA
MLBr_00048|M.leprae_Br4923 WRHWVHTVTRINLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGAGK
.
Mflv_5241|M.gilvum_PYR-GCK ASLSVALGMTLTPDSPAPQMARAVTEPAPEPVTK----PSPVKAAPKAPE
Mvan_1015|M.vanbaalenii_PYR-1 VSLSVALGMTLTPDSPAPQMARAVTEPTPEPVEKPVVKPAPVKAAPPEPE
MSMEG_1195|M.smegmatis_MC2_155 VASSAAVGIQLHPGAIAP-AAEVTDAGKSEPAASKPATPAAAPRPKPPAA
Mb1919|M.bovis_AF2122/97 ASLSLAVGIQLAPHNDTGTAKHGAHKPTPR--------------------
Rv1887|M.tuberculosis_H37Rv ASLSLAVGIQLAPHNDTGTAKHGAHKPTPR--------------------
TH_3639|M.thermoresistible__bu VSLSLALTPQPASE-------QRATSPTAG--------------------
MMAR_0602|M.marinum_M VSLAVSIRSEPGTRPD-PGQSVVTHLPAPAHAAPAPQPQAPAPQAPAPQA
MAV_4824|M.avium_104 VSLAIAIRPTANVRPS-PNQNVVVAPTRPAPAAPAP--------------
MUL_1227|M.ulcerans_Agy99 VTLTSDVRPAAATQPS-PREGVLTPASPAAPPKTATP-------------
MAB_4296c|M.abscessus_ATCC_199 VSLTVTVRSTVDQGPSSPDRGVVQNPLPAEAPKQAAPPPSPVEAPAPAVS
MLBr_00048|M.leprae_Br4923 TTVTVTLGSMFARVRNDRILVVDADTSCGNLADRAGRFSEANIADLLADK
.: : :
Mflv_5241|M.gilvum_PYR-GCK AAPVPPPPPPVAEPVA-VEMPMPEAPVVPEAPPPVYVEPLAPAPYVPPAP
Mvan_1015|M.vanbaalenii_PYR-1 AAPPPPAAPPVAEPVA-VEIPAPAAPALPEAPPPVYDEPLAPPPVVAPAP
MSMEG_1195|M.smegmatis_MC2_155 PAPAPEARPPAPEPAAPAPAPAAPAPVAEVNSVPAAEPPAYVPPAPAPEP
Mb1919|M.bovis_AF2122/97 ----------------------IAKAVAPAVPPPPTVTPPVPARAPRPAA
Rv1887|M.tuberculosis_H37Rv ----------------------IAKAVAPAVPPPPTVTPPVPARAPRPAA
TH_3639|M.thermoresistible__bu ----------------------DARPVAXXX-------PARPARRPRPGG
MMAR_0602|M.marinum_M QAPAPQAQVPAPAPAPQA-PAPRAPAPQAPAPQAQVPAPKAPAP-VPVPV
MAV_4824|M.avium_104 -APAPEAPAPAPAAAPQA-PAP--------APEAPAPAPAAPAP-APVQV
MUL_1227|M.ulcerans_Agy99 VPAKAPAQVPAPGPAPAASPVP-----VAAPPSVVQPPPVVRAP-RPTVV
MAB_4296c|M.abscessus_ATCC_199 PAPVQQVVAPAPQHNPAPAPKQVAPAPVQAAPQAPAPAPEAPAPAAPAPV
MLBr_00048|M.leprae_Br4923 DVKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVSKYY
.
Mflv_5241|M.gilvum_PYR-GCK AYVPPPPPANYLPPAP-----------------------PPAAPPYVPPV
Mvan_1015|M.vanbaalenii_PYR-1 AYVPPPPPANYLPPAPAAPAYVP----------------PAQVPAYVPPA
MSMEG_1195|M.smegmatis_MC2_155 AYVPPAPEPAYVPPPP---------------------------PAFVPPP
Mb1919|M.bovis_AF2122/97 QHEPPARVTSGEALTE---------------------------PNPPEEQ
Rv1887|M.tuberculosis_H37Rv QHEPPARVTSGEALTE---------------------------PNPPEEQ
TH_3639|M.thermoresistible__bu S--PPG--------------------------------------------
MMAR_0602|M.marinum_M AQA-PVPVPQAPAPVPVPIPQAP----------------APAPEAPVPAP
MAV_4824|M.avium_104 A---PVPVPEAPAPAPA------------------------APPPPPPAV
MUL_1227|M.ulcerans_Agy99 K---PPPQYIAPATQPRR---------------------TPAPQAPAPTP
MAB_4296c|M.abscessus_ATCC_199 PEEQPAPVAPPPAVVPVPIPLFPPVWEPPRRQENPWWPDRDRPRYTPPAQ
MLBr_00048|M.leprae_Br4923 NVMLADCGVGLFDPVTRGVLSTASG-------------VVIVTSTSVDAA
.
Mflv_5241|M.gilvum_PYR-GCK QTPLIPQQPVPQPRLRDR----------------------------IIER
Mvan_1015|M.vanbaalenii_PYR-1 QQPAYVPPAPQQPRLRDR----------------------------IIER
MSMEG_1195|M.smegmatis_MC2_155 PPPPLN---YPQPRLRDR----------------------------IIER
Mb1919|M.bovis_AF2122/97 PNASAPQQDRNDSQPITR----------------------------VLEH
Rv1887|M.tuberculosis_H37Rv PNASAPQQDRNDSQPITR----------------------------VLEH
TH_3639|M.thermoresistible__bu --------------------------------------------------
MMAR_0602|M.marinum_M VPIPVPIQIP-LPQIFGP---------------------------GGGGG
MAV_4824|M.avium_104 APIPVPIPLP-IPGLGGP---------------------------GFGGP
MUL_1227|M.ulcerans_Agy99 VQAPAPEVPP-PVAVPEP---------------------------APAPP
MAB_4296c|M.abscessus_ATCC_199 TQQPPIISIPGLPPIGGGDSDRGSHGGSRGGSGRGGWGDDGDSRGGSDSG
MLBr_00048|M.leprae_Br4923 RQAAIALDWLRHNGYQDLLSRACVVIN------------HVMPKEPNIAS
Mflv_5241|M.gilvum_PYR-GCK IPIINRFHEPPY--------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 IPIINRFHEPEY--------------------------------------
MSMEG_1195|M.smegmatis_MC2_155 IPIINRFHEPKPWG------------------------------------
Mb1919|M.bovis_AF2122/97 IPGAYGDSAPPAE-------------------------------------
Rv1887|M.tuberculosis_H37Rv IPGAYGDSAPPAE-------------------------------------
TH_3639|M.thermoresistible__bu --------------------------------------------------
MMAR_0602|M.marinum_M FPGGDDDRGGRGGG--RGGRHGGGHGGG--HGRGGFNIPFIPGI------
MAV_4824|M.avium_104 PGHGGGDGGGHGGGGFPGFPGGGGHGGGGFPGFGGGHGGFGHH-------
MUL_1227|M.ulcerans_Agy99 VPALVVER--------LVIQNDGVDLAE----------------------
MAB_4296c|M.abscessus_ATCC_199 SRGGWGDNGGSRGGWGDSGSSRGGSDSGSRGGWGGNSGSHGGGSGGGSNS
MLBr_00048|M.leprae_Br4923 KDLVQQFEQQIQPGRVVVLPWDKHIAAGTEIRLDRLDPLYRRRILELAAA
Mflv_5241|M.gilvum_PYR-GCK -----------
Mvan_1015|M.vanbaalenii_PYR-1 -----------
MSMEG_1195|M.smegmatis_MC2_155 -----------
Mb1919|M.bovis_AF2122/97 -----------
Rv1887|M.tuberculosis_H37Rv -----------
TH_3639|M.thermoresistible__bu -----------
MMAR_0602|M.marinum_M -----------
MAV_4824|M.avium_104 -----------
MUL_1227|M.ulcerans_Agy99 -----------
MAB_4296c|M.abscessus_ATCC_199 GFPWPFGGR--
MLBr_00048|M.leprae_Br4923 LSDDFERAGRH