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DLVLGLSMTSSSVRWVVVDGAAGEESRTIDRGSTPVDDGFDARALVDRLLQHSVHAVGLNWDITAESTVS AVWQAFTDRGVENVFAVSDVEAAEALARGIADIAGCERLVVCVAEPGPSVLAAVTPHGVTADRVDPSALT DVEALAPDAVFVLGSGDVAPVVAELEQRLQAPVVSAEEADLALARGAALASASAVSILDAQDAPARRKLT PTATLAGVLAAAVVTFVASLSVALGMTLTPDSPAPQMARAVTEPAPEPVTKPSPVKAAPKAPEAAPVPPP PPPVAEPVAVEMPMPEAPVVPEAPPPVYVEPLAPAPYVPPAPAYVPPPPPANYLPPAPPPAAPPYVPPVQ TPLIPQQPVPQPRLRDRIIERIPIINRFHEPPY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5241 | - | - | 100% (384) | hypothetical protein Mflv_5241 |
| M. gilvum PYR-GCK | Mflv_3300 | - | 4e-42 | 34.99% (423) | hypothetical protein Mflv_3300 |
| M. gilvum PYR-GCK | Mflv_0290 | - | 3e-33 | 27.87% (445) | hypothetical protein Mflv_0290 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1919 | - | 5e-34 | 31.89% (392) | hypothetical protein Mb1919 |
| M. tuberculosis H37Rv | Rv1887 | - | 5e-34 | 31.89% (392) | hypothetical protein Rv1887 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-09 | 37.23% (94) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_4296c | - | 3e-31 | 28.91% (467) | hypothetical protein MAB_4296c |
| M. marinum M | MMAR_2779 | - | 3e-32 | 29.62% (368) | hypothetical protein MMAR_2779 |
| M. avium 104 | MAV_4848 | - | 3e-32 | 28.89% (443) | hypothetical protein MAV_4848 |
| M. smegmatis MC2 155 | MSMEG_1195 | - | 1e-71 | 43.20% (419) | hypothetical protein MSMEG_1195 |
| M. thermoresistible (build 8) | TH_3639 | - | 1e-39 | 38.28% (303) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2968 | - | 8e-33 | 29.89% (368) | hypothetical protein MUL_2968 |
| M. vanbaalenii PYR-1 | Mvan_1015 | - | 1e-162 | 77.12% (389) | hypothetical protein Mvan_1015 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5241|M.gilvum_PYR-GCK -----MDLVLGLSMTSSSVRWVVVDGAAGE----ESRTIDRGSTPVDDG-
Mvan_1015|M.vanbaalenii_PYR-1 -------------MTASSIRWVLVDGATGE----ESVTIDRGSVPVDDA-
MSMEG_1195|M.smegmatis_MC2_155 -----MDLVLGLAMTSRAIRWVLVEGTTG-----AGDAIDRGAIAVDDAA
TH_3639|M.thermoresistible__bu -----MDFVLGLSVTSAGTRAVLVEGAAG-----DGATLDQFSSATTDDL
Mb1919|M.bovis_AF2122/97 -----MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAI
Rv1887|M.tuberculosis_H37Rv -----MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRNAQAI
MMAR_2779|M.marinum_M -----MDTVLGLSVTPTTVGWVLAEGHGADGAILDHHESQLHGSRGMRIV
MUL_2968|M.ulcerans_Agy99 MRCEVLDTVLGLSVTPTTVGWVLAEGHGADGAILDHHESQLHGSRGMRIV
MAB_4296c|M.abscessus_ATCC_199 -----MDVVLGVSMTPTTARLVLVEGAGADGRIVDTDTIVVSEG----EG
MAV_4848|M.avium_104 -----MDIVLGVSMAPGTVRLVAIEGQNADGVTVEQEEFAVGAAG-NSAN
MLBr_02395|M.leprae_Br4923 ----MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPV
. ..
Mflv_5241|M.gilvum_PYR-GCK -FDARA--LVDRLLQ------HSVHAVGLNWDITAESTVSAVWQAFTDRG
Mvan_1015|M.vanbaalenii_PYR-1 -FQADA--LLDRLLG------RPVHAIGLTWTVEAERTASAVWQGLTDRG
MSMEG_1195|M.smegmatis_MC2_155 AYEPDG--LLRGLVDDTVVQGHRIHAIGVTWTCDASVLATRVMGALESWG
TH_3639|M.thermoresistible__bu VLALSENPTFGPALN-AAASGDGISTIGVTCSHDATTAAGLVVDDLLARG
Mb1919|M.bovis_AF2122/97 HTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAG
Rv1887|M.tuberculosis_H37Rv HTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESLTGAG
MMAR_2779|M.marinum_M HTAEQVADEVWHAKEVASGAGHRLRMIGVTWGDEASAQAALLLEALTDAG
MUL_2968|M.ulcerans_Agy99 HTAEQVADEVWHAKEVASGAGHRLRMIGVTWSDEASAQAALLLEALTDAG
MAB_4296c|M.abscessus_ATCC_199 TTSEQVLSAIVGTRDGMLDGGHNLVSTGVVWSDHAE--AAELRDSLASRG
MAV_4848|M.avium_104 SAADQVIDAIIGTREGVFEGGHRLTSTGVTWTDPTG--AAALRDAIASHE
MLBr_02395|M.leprae_Br4923 GGSYPPPPPPGGSYPPPPPPGGSYPPPPPSTGAYAPPPPGPAIRSLPKEA
: :
Mflv_5241|M.gilvum_PYR-GCK VENVFAVSDVEAAEALARGIADIAGCERLVVCVAEPGPSVLAAVTPHGVT
Mvan_1015|M.vanbaalenii_PYR-1 VENVIAVSDVESAEALACGIADLAGCERVVVGLAEPGTSVIAAVTPDGVT
MSMEG_1195|M.smegmatis_MC2_155 HTNVIAVSEVEAAGILASGIAELTGHDDIAVCIIESDAAVAATVTADAVS
TH_3639|M.thermoresistible__bu CRNVVSVSELDAAEALATGLADLAGYTEIAVCIAEPDDAVIAVVGADDVV
Mb1919|M.bovis_AF2122/97 FDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDTHDGK
Rv1887|M.tuberculosis_H37Rv FDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDTHDGK
MMAR_2779|M.marinum_M FDNVVPVRLLDAVETLAEAIAPVIGYDQTAVCILEHDWATVVMVDTQDGK
MUL_2968|M.ulcerans_Agy99 FDNVVPVRLVDAVETLAEAIAPVIGYDQTAVCILEHDWATVVMVDTQDGK
MAB_4296c|M.abscessus_ATCC_199 IDGVEFFSALHAGGALAKAASSVTGYDKSALLVIEPQTATLAVVDSADGS
MAV_4848|M.avium_104 LGNVMLVSPLLAAAALAQTVGYALGYGHIGMLFVEPRSATLAVVDVSDGS
MLBr_02395|M.leprae_Br4923 YT--FWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYN---
. : : * . : .. .
Mflv_5241|M.gilvum_PYR-GCK ADRVDP---------------SALTD---VEALAPDAVFVLGSG-DVAPV
Mvan_1015|M.vanbaalenii_PYR-1 ADRVDP---------------AALTD---VDGFDPDAIFVLGSG-DVAGV
MSMEG_1195|M.smegmatis_MC2_155 ADRIARSPGDDDSVELIESLKAVLEE---STGGRTEGIFLLGSE-CDDLI
TH_3639|M.thermoresistible__bu LDGIGRAAAPAPEN--IADHLLTTLG---DTAATPQAVFVVGSAPDVGDV
Mb1919|M.bovis_AF2122/97 TQIAVKHVCRGLSG--LTSWLTGMFG---RDAWRPAGVVVVGSDSEVSEF
Rv1887|M.tuberculosis_H37Rv TQIAVKHVCRGLSG--LTSWLTGMFG---RDAWRPAGVVVVGSDSEVSEF
MMAR_2779|M.marinum_M TQTAVKHVRGGFDG--LNSWLTGMFD---RGAWRPAAVVVVGSDTDVEEF
MUL_2968|M.ulcerans_Agy99 TQTAVKHVRGGFDG--LNSWLTGMFD---RGAWRPAAVVVVGSDTDVEEF
MAB_4296c|M.abscessus_ATCC_199 IVGLASEPLITG---VTSGVLANLVNPLKGKENAPDGVFLLGLGTDVSDL
MAV_4848|M.avium_104 IVDLHRHQIPHGPGAPVAAELAAMVAGLDARDTRADGVFVVGCGTDIVAV
MLBr_02395|M.leprae_Br4923 -------------------------------VNQYCATQPTGIGMLAFWF
. * .
Mflv_5241|M.gilvum_PYR-GCK VAELEQRLQAPVVSAEEADLALARGAALASASAVSILDA-----------
Mvan_1015|M.vanbaalenii_PYR-1 VSALEQRSTVPVVSADEADLALARGAALASASAVSILDA-----------
MSMEG_1195|M.smegmatis_MC2_155 VASLSEAATVPVVSSAEADLAYPRGAALS--AALAINTP-----------
TH_3639|M.thermoresistible__bu AAALEATLEVPVLSAQEGDLALARGAALASARSAAVAYP-----------
Mb1919|M.bovis_AF2122/97 SWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVA-------
Rv1887|M.tuberculosis_H37Rv SWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVA-------
MMAR_2779|M.marinum_M SWQLEKALPVPVFAQTMAQVTIARGAALAAAQSTDFTDARLIA-------
MUL_2968|M.ulcerans_Agy99 SWQLEKALPVPVFAQTMAQVTIARGAALAAAQSTDFTDARLIA-------
MAB_4296c|M.abscessus_ATCC_199 AESLGDAIALPVNSPDQPELALARGAALASAQEPDFEASTALLGQAYSLE
MAV_4848|M.avium_104 KPALEAASPVPVTGPEEPDMALARGAALASANAPLFASSTAAL--AYALD
MLBr_02395|M.leprae_Br4923 AWLMATAYLVWNYGYRQGATGSSIGKTVMKFKVISEATG-----------
: . . * ::
Mflv_5241|M.gilvum_PYR-GCK --------------------------------------QDAPARRKLTPT
Mvan_1015|M.vanbaalenii_PYR-1 --------------------------------------QAAPARRRLSPT
MSMEG_1195|M.smegmatis_MC2_155 --------------------------------------SEEPKGLHFTKV
TH_3639|M.thermoresistible__bu --------------------------------------PARP--LRLTRV
Mb1919|M.bovis_AF2122/97 ----------------------------------DSVSQPTVAPRRSRHY
Rv1887|M.tuberculosis_H37Rv ----------------------------------DSVSQPTVAPRRSRHY
MMAR_2779|M.marinum_M ----------------------------------D-VSEPAPAPKRSLHY
MUL_2968|M.ulcerans_Agy99 ----------------------------------D-VSEPAPAPKRSLHY
MAB_4296c|M.abscessus_ATCC_199 GPTGTGFAHPDAVTES------AGEANTELREFEDFDDQ--PAERKPFLL
MAV_4848|M.avium_104 --PGTGEMDPPAFNPTYLDVWGDTGAGTGVRAYSAVPDEEEPAPRRPWSM
MLBr_02395|M.leprae_Br4923 ------------------------------------------------QP
Mflv_5241|M.gilvum_PYR-GCK ATLAGVLAAAVVTFVASLSVALGMTLTPDSPAPQMARAVTEP--------
Mvan_1015|M.vanbaalenii_PYR-1 ATLASVLATAVVTFVVSLSVALGMTLTPDSPAPQMARAVTEP--------
MSMEG_1195|M.smegmatis_MC2_155 GALSSVLAAAVVTLVVASSAAVGIQLHPGAIAP-AAEVTDAG--------
TH_3639|M.thermoresistible__bu GVLSSVLVAASLTFVVSLSLAL----TPQPASEQRATSPTAG--------
Mb1919|M.bovis_AF2122/97 AGAAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKP--------
Rv1887|M.tuberculosis_H37Rv AGAAAALAAAAVTFVASLSLAVGIQLAPHNDTGTAKHGAHKP--------
MMAR_2779|M.marinum_M AGAATTLAAAAVTFVGSLSLAIGLQLTPERHHTATGHAGHKP--------
MUL_2968|M.ulcerans_Agy99 AGAATTLAAAAVTFVGSLSLAIGLQLTPERHHTATGHAGHKP--------
MAB_4296c|M.abscessus_ATCC_199 VGAPLLLVFGICSIALAVSLTVTVRSTVDQGPSSPDRGVVQNPLPAEAPK
MAV_4848|M.avium_104 LLAGGALAG----IAAVIGGVVLVTLTSD-GHSTNTRHNQGVSVATPGIQ
MLBr_02395|M.leprae_Br4923 IGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADKIMT--------
:. :. :
Mflv_5241|M.gilvum_PYR-GCK APEPVTK-----PSPVKAAPKAPEAAPVPPP-PPPVAEPVA-VEMPMPEA
Mvan_1015|M.vanbaalenii_PYR-1 TPEPVEKPV-VKPAPVKAAPPEPEAAPPPPA-APPVAEPVA-VEIPAPAA
MSMEG_1195|M.smegmatis_MC2_155 KSEPAASKP-ATPAAAPRPKPPAAPAPAPEA-RPPAPEPAAPAPAPAAPA
TH_3639|M.thermoresistible__bu DARPVAX----------XXPARPARRPRPGG-SPPG--------------
Mb1919|M.bovis_AF2122/97 TPRIAKAVAPAVPPPPTVTPPVPARAPRPAAQHEPPARVTSGEALTEPNP
Rv1887|M.tuberculosis_H37Rv TPRIAKAVAPAVPPPPTVTPPVPARAPRPAAQHEPPARVTSGEALTEPNP
MMAR_2779|M.marinum_M TPEIVEAVAPVVPMPAQPEPSAPHQAPAPGAGQEP-IRLTAGEQITDAAP
MUL_2968|M.ulcerans_Agy99 TPEIVEAVAPVVPMPAQPEPSAPHQAPAPGAGQEP-IRLTAGEQITDAAP
MAB_4296c|M.abscessus_ATCC_199 QAAPPPSPVEAPAPAVSPAPVQQVVAPAPQHNPAPAPKQVAPAPVQAAPQ
MAV_4848|M.avium_104 LPAPPPS---NPPAAQPPAPSTPAPAPTPTEVAAPAPEPVQQAAPQTPVT
MLBr_02395|M.leprae_Br4923 ----------------------TVCLPI----------------------
*
Mflv_5241|M.gilvum_PYR-GCK PVVPEAPPPVYVEPLAPAPYVPPAPAYVPPPPPANYLPPAP-------PP
Mvan_1015|M.vanbaalenii_PYR-1 PALPEAPPPVYDEPLAPPPVVAPAPAYVPPPPPANYLPPAPAAPAYVPPA
MSMEG_1195|M.smegmatis_MC2_155 PVAEVNSVPAAEPPAYVPPAPAPEPAYVPPAPEPAYVPPPP---------
TH_3639|M.thermoresistible__bu --------------------------------------------------
Mb1919|M.bovis_AF2122/97 PEEQPNASAPQQDRNDSQP-ITRVLEHIPGAYG--DSAPPAE--------
Rv1887|M.tuberculosis_H37Rv PEEQPNASAPQQDRNDSQP-ITRVLEHIPGAYG--DSAPPAE--------
MMAR_2779|M.marinum_M VE-QPGGEAPQSEPADGSPMLTRVLTHIPGSYGEEEGSRPPE--------
MUL_2968|M.ulcerans_Agy99 VE-QPGGEAPQSEPADGSPMLTRVLTHIPGSYGEEEGSRPPE--------
MAB_4296c|M.abscessus_ATCC_199 APAPAPEAPAPAAP-APVPEEQPAP-VAPPPAVVPVPIPLFPPVWEPPRR
MAV_4848|M.avium_104 TAPPAPVYRAPARP-TPQYQPRPVEQPAPPPAAAPAPAAPPPAPAPPPAA
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_5241|M.gilvum_PYR-GCK AAPPYVPPVQTPLIPQQPVPQPRLRDRIIERIPIINRFHEPPY-------
Mvan_1015|M.vanbaalenii_PYR-1 QVPAYVPPAQQPAYVPPAPQQPRLRDRIIERIPIINRFHEPEY-------
MSMEG_1195|M.smegmatis_MC2_155 --PAFVPPPPPPPLN---YPQPRLRDRIIERIPIINRFHEPKPWG-----
TH_3639|M.thermoresistible__bu --------------------------------------------------
Mb1919|M.bovis_AF2122/97 --------------------------------------------------
Rv1887|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2779|M.marinum_M --------------------------------------------------
MUL_2968|M.ulcerans_Agy99 --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 QENPWWPDRDRPRYTPPAQTQQPPIISIPGLPPIGGGDSDRGSHGGSRGG
MAV_4848|M.avium_104 PPVPHQP--------PVTMYLHFPFVTVP--IPITPPAPPPGP-------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_5241|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1015|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1195|M.smegmatis_MC2_155 --------------------------------------------------
TH_3639|M.thermoresistible__bu --------------------------------------------------
Mb1919|M.bovis_AF2122/97 --------------------------------------------------
Rv1887|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2779|M.marinum_M --------------------------------------------------
MUL_2968|M.ulcerans_Agy99 --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 SGRGGWGDDGDSRGGSDSGSRGGWGDNGGSRGGWGDSGSSRGGSDSGSRG
MAV_4848|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_5241|M.gilvum_PYR-GCK ----------------------------
Mvan_1015|M.vanbaalenii_PYR-1 ----------------------------
MSMEG_1195|M.smegmatis_MC2_155 ----------------------------
TH_3639|M.thermoresistible__bu ----------------------------
Mb1919|M.bovis_AF2122/97 ----------------------------
Rv1887|M.tuberculosis_H37Rv ----------------------------
MMAR_2779|M.marinum_M ----------------------------
MUL_2968|M.ulcerans_Agy99 ----------------------------
MAB_4296c|M.abscessus_ATCC_199 GWGGNSGSHGGGSGGGSNSGFPWPFGGR
MAV_4848|M.avium_104 ----------------------------
MLBr_02395|M.leprae_Br4923 ----------------------------