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TGYHLAEMTTTSADEADLIAALRARDEVAFARLVDQHTPAMLRVARGYVASHEVAEEVVQETWIALLKGI DRFEGRSSLRTWLFTVMINIAKTRGLRDRTDADVQIAAYTGGTVDPKRFRDSDDPWPGHWKADEVPSPFP DTPEGSVLGGELLAVTRRELAKLPERQRLVVTMRDVLDMDSAEVSRLLDLSPANQRVLLHRGRAAVRQAL ENYLKEPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0782 | - | - | 100% (219) | ECF subfamily RNA polymerase sigma-24 factor |
| M. vanbaalenii PYR-1 | Mvan_0149 | - | 5e-12 | 30.46% (174) | RNA polymerase factor sigma-70 |
| M. vanbaalenii PYR-1 | Mvan_2297 | - | 9e-12 | 29.83% (181) | ECF subfamily RNA polymerase sigma-24 factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0188c | sigG | 1e-08 | 31.03% (174) | RNA polymerase factor sigma-70 |
| M. gilvum PYR-GCK | Mflv_0519 | - | 8e-14 | 31.25% (176) | RNA polymerase factor sigma-70 |
| M. tuberculosis H37Rv | Rv0182c | sigG | 1e-08 | 31.03% (174) | RNA polymerase factor sigma-70 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1248 | - | 2e-15 | 32.52% (206) | RNA polymerase sigma factor |
| M. marinum M | MMAR_3276 | - | 1e-32 | 41.15% (209) | alternative RNA polymerase sigma factor |
| M. avium 104 | MAV_2488 | - | 3e-25 | 40.93% (193) | RNA polymerase sigma factor, sigma-70 family protein |
| M. smegmatis MC2 155 | MSMEG_0219 | - | 7e-10 | 31.61% (155) | RNA polymerase factor sigma-70 |
| M. thermoresistible (build 8) | TH_0604 | sigG | 7e-13 | 31.55% (187) | PROBABLE ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGG (RNA |
| M. ulcerans Agy99 | MUL_1353 | - | 9e-30 | 40.00% (200) | alternative RNA polymerase sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0519|M.gilvum_PYR-GCK ----------------------------MSHPMRKLLFVTVLA-----LD
MSMEG_0219|M.smegmatis_MC2_155 ----------------------------MSVILRKLTTVTVLAH---KLD
TH_0604|M.thermoresistible__bu ----------------------------MSVMLRTLLHVTVLT-----AP
Mb0188c|M.bovis_AF2122/97 MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAENSGREP
Rv0182c|M.tuberculosis_H37Rv MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAENSGREP
MMAR_3276|M.marinum_M ---------------------------MAVPKRTIVDDRWATESDLIAAL
MUL_1353|M.ulcerans_Agy99 -------------------------------------------------M
Mvan_0782|M.vanbaalenii_PYR-1 ---------------------------MTGYHLAEMTTTSADEADLIAAL
MAV_2488|M.avium_104 -----------------------------------MVTPVAVPPEGTDAG
MAB_1248|M.abscessus_ATCC_1997 --------------------------MVLPLLPRGELLASLSDEMLARRA
Mflv_0519|M.gilvum_PYR-GCK EGGAKDAFLADAQKYRRELLAHCYRMTGSLHDAEDLVQETYLRAWKSYDR
MSMEG_0219|M.smegmatis_MC2_155 DDSPADAFLAEAQTYRRELLAHCYRMTGSLHDAEDLVQETYLRAWKSYQG
TH_0604|M.thermoresistible__bu PDGGSDAFLADAEQYRRELLAHCYRMTGSLHDAEDLVQETFLRAWKSHHK
Mb0188c|M.bovis_AF2122/97 ADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAWKAYEG
Rv0182c|M.tuberculosis_H37Rv ADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAWKAYEG
MMAR_3276|M.marinum_M QAGDGKAFRALVETLHAPLVRLAGIYVS-RATAEDAVQNAWVSAVRSIGK
MUL_1353|M.ulcerans_Agy99 QAGDGQAFRALVETLHAPLVRLASIYVS-RATAEDAVQNAWVSAVRSIGK
Mvan_0782|M.vanbaalenii_PYR-1 RARDEVAFARLVDQHTPAMLRVARGYVASHEVAEEVVQETWIALLKGIDR
MAV_2488|M.avium_104 RLVGGVPLARLVRDFHRPMLNFARTMVDSPAVAEEAVQEAWLQVLRSSDS
MAB_1248|M.abscessus_ATCC_1997 QQGDSEAFDVLVVRHGPALLRFVARTYPERAEYDDIVQETFIAAWKGLPS
: . :: :: **:: : :.
Mflv_0519|M.gilvum_PYR-GCK FEGKSSVRTWLYRIATNTCLTALDGRKRRPLPSGLGGPSADPYADLTERH
MSMEG_0219|M.smegmatis_MC2_155 FQGRSSVRTWLYRIATNTCLTSLEGRSRRPLPSGLGTPSSAPTDQITEHH
TH_0604|M.thermoresistible__bu FEGKASVRTWLYKIATNACLTALDGRQRRPLPTGLGAPSSDPTDDIVARE
Mb0188c|M.bovis_AF2122/97 FAGKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGRPSADPSGELVERR
Rv0182c|M.tuberculosis_H37Rv FAGKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGRPSADPSGELVERR
MMAR_3276|M.marinum_M FEGRASVRTWMFRVVLNQVHTLAR-KEANTVPFATAGPEVDPRPSVDPER
MUL_1353|M.ulcerans_Agy99 FEGRASIRTWMFRVVLNQVHTLAR-KEANTVPFANAGPEVDPRPSVDPER
Mvan_0782|M.vanbaalenii_PYR-1 FEGRSSLRTWLFTVMINIAKTRGL-RDRTDADVQIAAYTGG---TVDPKR
MAV_2488|M.avium_104 FQGRSSVGTWLFGIVKHTAARHRR-RESRIRRHEVLADADIEAVDPLSGR
MAB_1248|M.abscessus_ATCC_1997 FAFRSQFRTWLYSLASRKTVDAMR-RRRRDFDIDEVPEVADAGAGPSER-
* ::.. **:. : . :
Mflv_0519|M.gilvum_PYR-GCK EIAWLEPIPDDPH--EDPADPSVIAES---RESVRLALIAALQHLSPRQR
MSMEG_0219|M.smegmatis_MC2_155 EVPWLEPLPDG----DDPADPSQIVGT---RESVRLAFVAALQHLSPRQR
TH_0604|M.thermoresistible__bu EVPWLEPLPDD------AADPSTIVGS---RESVRLAFVAALQHLPPRQR
Mb0188c|M.bovis_AF2122/97 EVSWLEPLPDVT---DDPADPSTIVGN---RESVRLAFVAALQHLSPRQR
Rv0182c|M.tuberculosis_H37Rv EVSWLEPLPDVT---DDPADPSTIVGN---RESVRLAFVAALQHLSPRQR
MMAR_3276|M.marinum_M LIDP-ELGPNHWR--DVPVRWDLLPEQRLLSAEVRSVVVEALQQLPGAQR
MUL_1353|M.ulcerans_Agy99 LIDP-ELGPNHWR--DVPVRWDLLPEQRLLSAEVRSVVVEALQKLPGAQR
Mvan_0782|M.vanbaalenii_PYR-1 FRDSDDPWPGHWKADEVPSPFPDTPEGSVLGGELLAVTRRELAKLPERQR
MAV_2488|M.avium_104 MHPAGHPDAGHWR---VPPSRRFLPEDQTVHRELLGYLREALDALPARQR
MAB_1248|M.abscessus_ATCC_1997 ----------------------------ALDGDFLAALSRELSQLPYAAR
.. * *. *
Mflv_0519|M.gilvum_PYR-GCK AVLVLREVLQWKAAEVGEVIGASTAAVNSLLQRARAQLDEVAPSRDDQPV
MSMEG_0219|M.smegmatis_MC2_155 AVLVMREVLQWKASEVGEAIGASTAAVNSLLQRARAQLEAVGPNEDDKIE
TH_0604|M.thermoresistible__bu AVLLLREVLQWRAAEVAEVLNTSTAAVNSLLQRARAQLDQVGPSEDDELV
Mb0188c|M.bovis_AF2122/97 AVLLLRDVLQWKSAEVADAIGTSTVAVNSLLQRARSQLQTVRPSAADRLS
Rv0182c|M.tuberculosis_H37Rv AVLLLRDVLQWKSAEVADAIGTSTVAVNSLLQRARSQLQTVRPSAADRLS
MMAR_3276|M.marinum_M EVVAMRDLEGWSSEETCEALGISAVNQRVLLHRGRTALRAILEEYFHDN-
MUL_1353|M.ulcerans_Agy99 EVVAMRDLERWSSEETCEALGISAVNQRVLLHRGRTALRAILEEYFHDH-
Mvan_0782|M.vanbaalenii_PYR-1 LVVTMRDVLDMDSAEVSRLLDLSPANQRVLLHRGRAAVRQALENYLKEPV
MAV_2488|M.avium_104 QLVILRDLVGISAEEAAELLQLSAEAQRALLYRARGNLRNELEKRYQP--
MAB_1248|M.abscessus_ATCC_1997 AAWWLREVYDLPLAEIATVLRTTEGSVRGNLQRTRKRLAETLKDFRP---
:*:: * : : . * * * : .
Mflv_0519|M.gilvum_PYR-GCK SPESPQAAEALAKYIAAFEDYDMDRLVELFTADAVWEMPPFDGWYSGPAD
MSMEG_0219|M.smegmatis_MC2_155 APDSPQAQATLDRYIAAFEAYDIDKLVELFTEEAIWEMPPFDSWYQGPQA
TH_0604|M.thermoresistible__bu PPESPEAQELLTRYIDAFESYDIDKLVELFTADAVWEMPPFDGWYQGPQN
Mb0188c|M.bovis_AF2122/97 APDSPEAQDLLARYIAAFEAYDIDRLVELFTAEAIWEMPPYTGWYQGAQA
Rv0182c|M.tuberculosis_H37Rv APDSPEAQDLLARYIAAFEAYDIDRLVELFTAEAIWEMPPYTGWYQGAQA
MMAR_3276|M.marinum_M --------------------------------------------------
MUL_1353|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0782|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2488|M.avium_104 --------------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0519|M.gilvum_PYR-GCK IIALSKYHCPAAGAGDMRFLRTTANGQPVAALYMRNPETNVHEAFQLHVL
MSMEG_0219|M.smegmatis_MC2_155 IGDLSRYKCPAEEPGDMRFLQTTANGQPAAAMYMLNRETGRHEAFQLHVL
TH_0604|M.thermoresistible__bu IVTLSKTHCPAERPGDMRLIPTTANGQPAGAMYLRNPETGTHEAFQMHVL
Mb0188c|M.bovis_AF2122/97 IVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAG--DVHLPFQLHVL
Rv0182c|M.tuberculosis_H37Rv IVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAG--DVHLPFQLHVL
MMAR_3276|M.marinum_M --------------------------------------------------
MUL_1353|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0782|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2488|M.avium_104 --------------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0519|M.gilvum_PYR-GCK DLRTRGIAHVVAFMDVSLFRKFGLPETL
MSMEG_0219|M.smegmatis_MC2_155 DITADGISHVVAFMGEGLFKKFGLPETL
TH_0604|M.thermoresistible__bu AIGPGGISHVVAFH-MPSFAPFGLPDSL
Mb0188c|M.bovis_AF2122/97 DMAADRVSHVVAFLDTTLFPKFGLPDSL
Rv0182c|M.tuberculosis_H37Rv DMAADRVSHVVAFLDTTLFPKFGLPDSL
MMAR_3276|M.marinum_M ----------------------------
MUL_1353|M.ulcerans_Agy99 ----------------------------
Mvan_0782|M.vanbaalenii_PYR-1 ----------------------------
MAV_2488|M.avium_104 ----------------------------
MAB_1248|M.abscessus_ATCC_1997 ----------------------------