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MSRPVALITGPTSGLGEGFARRYAVDGFDLVLVARDVERLNRLAAELHDEAGTNVEVIRADLADAADRAV VADRLRAGVRVLVNNAGFGTSGEFWSADYALLQTQLDVNVTAVMQFTHAALPPMLAAGEGTVLNVASVAG LLPGRGSTYSASKAWVVSFSEGLANGLGGTGVGVHALCPGFVHTEFHERAGIDMAGTASFLWLEVDDVVR ETMASIAKHKVVIIPGLQYKALTTGGRMVPRNLVRALTKVVGKGRGRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0661 | - | - | 100% (258) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_3113 | - | 3e-41 | 42.50% (240) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_3324 | - | 3e-32 | 36.19% (257) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1571 | - | 4e-47 | 42.41% (257) | ketoacyl reductase |
| M. gilvum PYR-GCK | Mflv_0244 | - | 1e-130 | 89.53% (258) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1544 | - | 4e-47 | 42.41% (257) | ketoacyl reductase |
| M. leprae Br4923 | MLBr_00429 | - | 1e-33 | 35.37% (246) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4261c | - | 5e-98 | 69.26% (257) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0648 | - | 1e-106 | 73.26% (258) | ketoacyl reductase |
| M. avium 104 | MAV_4791 | - | 1e-102 | 70.93% (258) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0737 | - | 1e-115 | 79.84% (258) | dehydrogenase |
| M. thermoresistible (build 8) | TH_4326 | - | 1e-113 | 79.07% (258) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0124 | - | 1e-105 | 72.87% (258) | ketoacyl reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0661|M.vanbaalenii_PYR-1 -----MSRP----VALITGPTSGLGEGFARRYAVDGFDLVLVARDVERLN
Mflv_0244|M.gilvum_PYR-GCK -----MTRP----VALITGPTSGLGEGFARRYAVDGYDLVLVARDESRLN
TH_4326|M.thermoresistible__bu -----MPRP----VALITGPTSGLGEGFARRYAADGHDLVLVARDVQRLE
MSMEG_0737|M.smegmatis_MC2_155 -----MPRP----VALITGPTSGLGAGFARRYALEGYDLVFVARDQQRLE
MAB_4261c|M.abscessus_ATCC_199 MAATNSARP----VALITGPTSGLGGGFARKYASQGYDVVLVARDEQRLG
MMAR_0648|M.marinum_M -----MPRP----VALITGPTSGIGAGYARRYAQDGYDLILVARDVDRLK
MUL_0124|M.ulcerans_Agy99 -----MPRP----VALITGPTSGIGAGYARRYAQDGYDLILVARDVDRLT
MAV_4791|M.avium_104 -----MPRP----VALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLT
Mb1571|M.bovis_AF2122/97 ---MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLD
Rv1544|M.tuberculosis_H37Rv ---MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLD
MLBr_00429|M.leprae_Br4923 ---MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLV
. * .::**.:..:* * * *. ::.:** . *
Mvan_0661|M.vanbaalenii_PYR-1 RLAAELHDEAGTNVEVIRADLADAADRAVVADRLRAG-VRVLVNNAGFGT
Mflv_0244|M.gilvum_PYR-GCK TLAAELRDEAGTAVEVIRADLADDADRALVADRLRAG-VQVLVNNAGFGT
TH_4326|M.thermoresistible__bu QLAAELRQSAGIDVEVLPADLAVAADRAKVADRLADG-VQVLVNNAGFGT
MSMEG_0737|M.smegmatis_MC2_155 QLADELHHEAGATVETIAADLAVADDRARVAERVRQG-VRVLVNNAGFAT
MAB_4261c|M.abscessus_ATCC_199 ALADELTCRFGVYAEALPADLADAADRARVADRLAAG-VSVLVNNAGFAT
MMAR_0648|M.marinum_M QLAVELEDDAG-NVEILPADLADAAGRDKVAERLSRG-VRVLVNNAGFAT
MUL_0124|M.ulcerans_Agy99 QSAVELEDDAG-NVEILPADLADAAGRDKVAERLSRG-VRVLVNNAGFAT
MAV_4791|M.avium_104 ALAGELRDRAG-NIEILPADLGDAVDRQRVGERLAGG-VRVLVNNAGFAT
Mb1571|M.bovis_AF2122/97 ELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGT
Rv1544|M.tuberculosis_H37Rv ELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGT
MLBr_00429|M.leprae_Br4923 DLAARLADKYRVAVEVRPADLTDPSERVKLADELTVRPISILCANAGTAT
* .* * ** * :.:.: : * .** .*
Mvan_0661|M.vanbaalenii_PYR-1 SGEFWSADYALLQTQLDVNVTAVMQFTHAALPPMLAAGEGTVLNVASVAG
Mflv_0244|M.gilvum_PYR-GCK SGEFWTTDYAVLQSQLDVNVTAVMQLTHAALPSMLDAGRGTVLNVASVAG
TH_4326|M.thermoresistible__bu SGEFWTADPTLLQAQLDVNVTAVMHLTHAALPPMLDAHRGTIINVASVAG
MSMEG_0737|M.smegmatis_MC2_155 SGEFWTADFARLRAQLDVNVTAVMELTHAALPAMLDAHEGTIINVASVAG
MAB_4261c|M.abscessus_ATCC_199 AGEFWTAAPELLHSQLDVNVTAVMELTRAALPSMIEAGAGTVINVASVAG
MMAR_0648|M.marinum_M SGEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGTVINIASVAG
MUL_0124|M.ulcerans_Agy99 SGEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGTVINIASVAG
MAV_4791|M.avium_104 SGDFWHTDPALLQSQLDVNVTAVMHLTRAALPAMLDAGAGTVINIASIAG
Mb1571|M.bovis_AF2122/97 SGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAG
Rv1544|M.tuberculosis_H37Rv SGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAG
MLBr_00429|M.leprae_Br4923 FGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAG
* . :: :*. *: .:* *.** *: * :: .* **
Mvan_0661|M.vanbaalenii_PYR-1 LLPG-RGSTYSASKAWVVSFSEGLANGLGGTGVGVHALCPGFVHTEFHER
Mflv_0244|M.gilvum_PYR-GCK LLPG-RGSTYSASKAWVVSFTEGLANGLDGTGVGVHALCPGFVHTEFHER
TH_4326|M.thermoresistible__bu LLPG-RGSTYSASKAWVIAFSEGLANGLTGTGVGIHVVCPGFVRTEFHQR
MSMEG_0737|M.smegmatis_MC2_155 LVPG-RGSTYSASKAWVVSFTEGLANGLIGTGVGVHALCPGFVRTEFHAR
MAB_4261c|M.abscessus_ATCC_199 LVSG-RGSTYSASKAWVVSFTEGLANGLLGTGVGMHVLCPGFIHTEFHER
MMAR_0648|M.marinum_M LLSG-RGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPGYVHTEFHAR
MUL_0124|M.ulcerans_Agy99 LLSG-RGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPGYVHTEFHAR
MAV_4791|M.avium_104 LLPG-RGSTYSASKAWVISFSEGLSVGLQGTGVSVHAVCPGYVRTEFHAR
Mb1571|M.bovis_AF2122/97 FQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEI
Rv1544|M.tuberculosis_H37Rv FQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEI
MLBr_00429|M.leprae_Br4923 NSPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDH
. :.*:*:**:. :*:*.: * *:** : :.** : **
Mvan_0661|M.vanbaalenii_PYR-1 AGID--MAGTASFLWLEVDDVVRETMASIAKHKVVIIPGLQYKALTTGGR
Mflv_0244|M.gilvum_PYR-GCK AGID--MAGTAGFLWLEVDDVVRETMADVAKNRVVIIPGLQYKALTTGGR
TH_4326|M.thermoresistible__bu AGID--MSGTPSILYLDVDDVVRTTVARVRKGDVVIVPGLQYKVLTTVGR
MSMEG_0737|M.smegmatis_MC2_155 AGID--MAGTPSFMWLEVDDVVRDCLADVAKDKVVIVPGLQYKALTTGGR
MAB_4261c|M.abscessus_ATCC_199 AGIE--MGTIPEFMWLQVDDVVNACLHDIAAGKVLIVPGVQYKAITSVTR
MMAR_0648|M.marinum_M AGID--MTKLPSFMWLDVDDVIQESLADIADGKVISIPGVQYKALVGAGR
MUL_0124|M.ulcerans_Agy99 AGID--MTKLPSFMWLDVDDVIQESLADIADGKVIGIPGVQYKALVGAGR
MAV_4791|M.avium_104 AGID--MSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAER
Mb1571|M.bovis_AF2122/97 ASA---ERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGR
Rv1544|M.tuberculosis_H37Rv ASA---ERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGR
MLBr_00429|M.leprae_Br4923 DEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKAMSVASR
: :. ... : : :**: * : *
Mvan_0661|M.vanbaalenii_PYR-1 MVPRNLVRALTKVVGKGRGRT---
Mflv_0244|M.gilvum_PYR-GCK LVPRNVVRALTKVVGKGRGRT---
TH_4326|M.thermoresistible__bu LVPRKLVRALTKVVGKGRGRT---
MSMEG_0737|M.smegmatis_MC2_155 MAPRNLVRAVTKVVGKGRART---
MAB_4261c|M.abscessus_ATCC_199 LIPRGLVRKYNSVVGRGRGRT---
MMAR_0648|M.marinum_M MIPRGLLRAVMKRVGGGRGRT---
MUL_0124|M.ulcerans_Agy99 MIPRGLLRAVMKRVGGGRGRT---
MAV_4791|M.avium_104 LIPRTLMRAITKRVGGGRGRT---
Mb1571|M.bovis_AF2122/97 FAPRSLLLPAIR-IGNRLRGGPSR
Rv1544|M.tuberculosis_H37Rv FAPRSLLLPAIR-IGNRLRGGPSR
MLBr_00429|M.leprae_Br4923 YAPRAIVASIVGNFYKKLGGG---
** :: .