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MPRPVALITGPTSGLGAGFARRYALEGYDLVFVARDQQRLEQLADELHHEAGATVETIAADLAVADDRAR VAERVRQGVRVLVNNAGFATSGEFWTADFARLRAQLDVNVTAVMELTHAALPAMLDAHEGTIINVASVAG LVPGRGSTYSASKAWVVSFTEGLANGLIGTGVGVHALCPGFVRTEFHARAGIDMAGTPSFMWLEVDDVVR DCLADVAKDKVVIVPGLQYKALTTGGRMAPRNLVRAVTKVVGKGRART
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0737 | - | - | 100% (258) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4722 | - | 3e-30 | 33.59% (256) | short-chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4859 | - | 1e-21 | 37.44% (195) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1571 | - | 8e-46 | 40.62% (256) | ketoacyl reductase |
| M. gilvum PYR-GCK | Mflv_0244 | - | 1e-115 | 79.07% (258) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1544 | - | 8e-46 | 40.62% (256) | ketoacyl reductase |
| M. leprae Br4923 | MLBr_00429 | - | 9e-34 | 34.80% (250) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4261c | - | 1e-100 | 71.09% (256) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0648 | - | 1e-100 | 70.93% (258) | ketoacyl reductase |
| M. avium 104 | MAV_4791 | - | 1e-100 | 70.16% (258) | dehydrogenase |
| M. thermoresistible (build 8) | TH_4326 | - | 1e-111 | 77.52% (258) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0124 | - | 1e-99 | 70.54% (258) | ketoacyl reductase |
| M. vanbaalenii PYR-1 | Mvan_0661 | - | 1e-115 | 79.84% (258) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0244|M.gilvum_PYR-GCK -----MTRP----VALITGPTSGLGEGFARRYAVDGYDLVLVARDESRLN
Mvan_0661|M.vanbaalenii_PYR-1 -----MSRP----VALITGPTSGLGEGFARRYAVDGFDLVLVARDVERLN
TH_4326|M.thermoresistible__bu -----MPRP----VALITGPTSGLGEGFARRYAADGHDLVLVARDVQRLE
MSMEG_0737|M.smegmatis_MC2_155 -----MPRP----VALITGPTSGLGAGFARRYALEGYDLVFVARDQQRLE
MAB_4261c|M.abscessus_ATCC_199 MAATNSARP----VALITGPTSGLGGGFARKYASQGYDVVLVARDEQRLG
MMAR_0648|M.marinum_M -----MPRP----VALITGPTSGIGAGYARRYAQDGYDLILVARDVDRLK
MUL_0124|M.ulcerans_Agy99 -----MPRP----VALITGPTSGIGAGYARRYAQDGYDLILVARDVDRLT
MAV_4791|M.avium_104 -----MPRP----VALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLT
Mb1571|M.bovis_AF2122/97 ---MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLD
Rv1544|M.tuberculosis_H37Rv ---MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLD
MLBr_00429|M.leprae_Br4923 ---MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLV
. * .::**.:..:* * * *. ::.:** . *
Mflv_0244|M.gilvum_PYR-GCK TLAAELRDEAGTAVEVIRADLADDADRALVADRLRAG-VQVLVNNAGFGT
Mvan_0661|M.vanbaalenii_PYR-1 RLAAELHDEAGTNVEVIRADLADAADRAVVADRLRAG-VRVLVNNAGFGT
TH_4326|M.thermoresistible__bu QLAAELRQSAGIDVEVLPADLAVAADRAKVADRLADG-VQVLVNNAGFGT
MSMEG_0737|M.smegmatis_MC2_155 QLADELHHEAGATVETIAADLAVADDRARVAERVRQG-VRVLVNNAGFAT
MAB_4261c|M.abscessus_ATCC_199 ALADELTCRFGVYAEALPADLADAADRARVADRLAAG-VSVLVNNAGFAT
MMAR_0648|M.marinum_M QLAVELEDDAG-NVEILPADLADAAGRDKVAERLSRG-VRVLVNNAGFAT
MUL_0124|M.ulcerans_Agy99 QSAVELEDDAG-NVEILPADLADAAGRDKVAERLSRG-VRVLVNNAGFAT
MAV_4791|M.avium_104 ALAGELRDRAG-NIEILPADLGDAVDRQRVGERLAGG-VRVLVNNAGFAT
Mb1571|M.bovis_AF2122/97 ELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGT
Rv1544|M.tuberculosis_H37Rv ELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGT
MLBr_00429|M.leprae_Br4923 DLAARLADKYRVAVEVRPADLTDPSERVKLADELTVRPISILCANAGTAT
* .* * ** * :.:.: : * .** .*
Mflv_0244|M.gilvum_PYR-GCK SGEFWTTDYAVLQSQLDVNVTAVMQLTHAALPSMLDAGRGTVLNVASVAG
Mvan_0661|M.vanbaalenii_PYR-1 SGEFWSADYALLQTQLDVNVTAVMQFTHAALPPMLAAGEGTVLNVASVAG
TH_4326|M.thermoresistible__bu SGEFWTADPTLLQAQLDVNVTAVMHLTHAALPPMLDAHRGTIINVASVAG
MSMEG_0737|M.smegmatis_MC2_155 SGEFWTADFARLRAQLDVNVTAVMELTHAALPAMLDAHEGTIINVASVAG
MAB_4261c|M.abscessus_ATCC_199 AGEFWTAAPELLHSQLDVNVTAVMELTRAALPSMIEAGAGTVINVASVAG
MMAR_0648|M.marinum_M SGEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGTVINIASVAG
MUL_0124|M.ulcerans_Agy99 SGEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGTVINIASVAG
MAV_4791|M.avium_104 SGDFWHTDPALLQSQLDVNVTAVMHLTRAALPAMLDAGAGTVINIASIAG
Mb1571|M.bovis_AF2122/97 SGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAG
Rv1544|M.tuberculosis_H37Rv SGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAG
MLBr_00429|M.leprae_Br4923 FGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAG
* . :: :*. *: .:* *.** *: * :: .* **
Mflv_0244|M.gilvum_PYR-GCK LLPG-RGSTYSASKAWVVSFTEGLANGLDGTGVGVHALCPGFVHTEFHER
Mvan_0661|M.vanbaalenii_PYR-1 LLPG-RGSTYSASKAWVVSFSEGLANGLGGTGVGVHALCPGFVHTEFHER
TH_4326|M.thermoresistible__bu LLPG-RGSTYSASKAWVIAFSEGLANGLTGTGVGIHVVCPGFVRTEFHQR
MSMEG_0737|M.smegmatis_MC2_155 LVPG-RGSTYSASKAWVVSFTEGLANGLIGTGVGVHALCPGFVRTEFHAR
MAB_4261c|M.abscessus_ATCC_199 LVSG-RGSTYSASKAWVVSFTEGLANGLLGTGVGMHVLCPGFIHTEFHER
MMAR_0648|M.marinum_M LLSG-RGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPGYVHTEFHAR
MUL_0124|M.ulcerans_Agy99 LLSG-RGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPGYVHTEFHAR
MAV_4791|M.avium_104 LLPG-RGSTYSASKAWVISFSEGLSVGLQGTGVSVHAVCPGYVRTEFHAR
Mb1571|M.bovis_AF2122/97 FQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEI
Rv1544|M.tuberculosis_H37Rv FQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEI
MLBr_00429|M.leprae_Br4923 NSPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDH
. :.*:*:**:. :*:*.: * *:** : :.** : **
Mflv_0244|M.gilvum_PYR-GCK AGID--MAGTAGFLWLEVDDVVRETMADVAKNRVVIIPGLQYKALTTGGR
Mvan_0661|M.vanbaalenii_PYR-1 AGID--MAGTASFLWLEVDDVVRETMASIAKHKVVIIPGLQYKALTTGGR
TH_4326|M.thermoresistible__bu AGID--MSGTPSILYLDVDDVVRTTVARVRKGDVVIVPGLQYKVLTTVGR
MSMEG_0737|M.smegmatis_MC2_155 AGID--MAGTPSFMWLEVDDVVRDCLADVAKDKVVIVPGLQYKALTTGGR
MAB_4261c|M.abscessus_ATCC_199 AGIE--MGTIPEFMWLQVDDVVNACLHDIAAGKVLIVPGVQYKAITSVTR
MMAR_0648|M.marinum_M AGID--MTKLPSFMWLDVDDVIQESLADIADGKVISIPGVQYKALVGAGR
MUL_0124|M.ulcerans_Agy99 AGID--MTKLPSFMWLDVDDVIQESLADIADGKVIGIPGVQYKALVGAGR
MAV_4791|M.avium_104 AGID--MSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAER
Mb1571|M.bovis_AF2122/97 ASA---ERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGR
Rv1544|M.tuberculosis_H37Rv ASA---ERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGR
MLBr_00429|M.leprae_Br4923 DEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKAMSVASR
: :. ... : : :**: * : *
Mflv_0244|M.gilvum_PYR-GCK LVPRNVVRALTKVVGKGRGRT---
Mvan_0661|M.vanbaalenii_PYR-1 MVPRNLVRALTKVVGKGRGRT---
TH_4326|M.thermoresistible__bu LVPRKLVRALTKVVGKGRGRT---
MSMEG_0737|M.smegmatis_MC2_155 MAPRNLVRAVTKVVGKGRART---
MAB_4261c|M.abscessus_ATCC_199 LIPRGLVRKYNSVVGRGRGRT---
MMAR_0648|M.marinum_M MIPRGLLRAVMKRVGGGRGRT---
MUL_0124|M.ulcerans_Agy99 MIPRGLLRAVMKRVGGGRGRT---
MAV_4791|M.avium_104 LIPRTLMRAITKRVGGGRGRT---
Mb1571|M.bovis_AF2122/97 FAPRSLLLPAIR-IGNRLRGGPSR
Rv1544|M.tuberculosis_H37Rv FAPRSLLLPAIR-IGNRLRGGPSR
MLBr_00429|M.leprae_Br4923 YAPRAIVASIVGNFYKKLGGG---
** :: .