For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GLFDFYSDLMQHVGESMQRVDPFGPMGAAGEAVTSLFAVGNIVGDHGTDAMWNLAGDAGDVASVAQSMLP FAKQTLIIEGGLKMISVMEEQSGGANVPSEGESYSDSAHRFNQVGDTLASAMPDDRWRGTAADAYTLANE QQYARAGKLADADLKVRMALSAEAGEVRTARRMFNQAATVLGNAIVPALAARALGKHGKAISYGIETGAV ASSMPICIWHMTQLAGHSARAAETLKDAVALYEQVANEGYSVRM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | - | 100% (255) | hypothetical protein Mvan_0656 |
| M. vanbaalenii PYR-1 | Mvan_4060 | - | 6e-07 | 32.91% (79) | hypothetical protein Mvan_4060 |
| M. vanbaalenii PYR-1 | Mvan_5688 | - | 2e-06 | 23.84% (172) | hypothetical protein Mvan_5688 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3646c | - | 3e-07 | 27.92% (154) | hypothetical protein Mb3646c |
| M. gilvum PYR-GCK | Mflv_0157 | - | 4e-23 | 30.09% (216) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3616c | - | 4e-07 | 26.58% (158) | hypothetical protein Rv3616c |
| M. leprae Br4923 | MLBr_00405 | - | 4e-08 | 27.06% (170) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5416 | - | 3e-11 | 27.78% (144) | hypothetical protein MMAR_5416 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0723 | - | 7e-20 | 32.60% (181) | hypothetical protein MSMEG_0723 |
| M. thermoresistible (build 8) | TH_2666 | - | 5e-24 | 32.37% (207) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_5045 | - | 3e-10 | 24.14% (232) | hypothetical protein MUL_5045 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3646c|M.bovis_AF2122/97 MSRAFIIDPTISAIDGLYDLLGIGIPNQGGILYSSLEYFEKALEELAAAF
Rv3616c|M.tuberculosis_H37Rv MSRAFIIDPTISAIDGLYDLLGIGIPNQGGILYSSLEYFEKALEELAAAF
MLBr_00405|M.leprae_Br4923 MSGAFIIDPTLKAIEAWHALLGIGVPNDGGVLYSSLSFFEKALEHLAAAF
Mflv_0157|M.gilvum_PYR-GCK --------------------------MALGKLWVDANYFYGVADHANMMS
TH_2666|M.thermoresistible__bu ----------------------------MLDAYSTLNWGKSVVEHPMSAK
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 ----------------------------MGLFDFYSDLMQHVGESMQRVD
MMAR_5416|M.marinum_M --------------------------------------------------
MUL_5045|M.ulcerans_Agy99 ------------------------------------MHPDEAATHNRSFE
Mb3646c|M.bovis_AF2122/97 PGDGWLGSAADKYAGKNRNHVNFFQELADLDR--QLISLIHDQANAVQTT
Rv3616c|M.tuberculosis_H37Rv PGDGWLGSAADKYAGKNRNHVNFFQELADLDR--QLISLIHDQANAVQTT
MLBr_00405|M.leprae_Br4923 PGDGWLGSAADKYAGQNRKRVDIFQELAELDK--ELIELIHNQANSVQTT
Mflv_0157|M.gilvum_PYR-GCK SDPALG------SAAIATDAAILMQSLA--------------AVGGSTMG
TH_2666|M.thermoresistible__bu DHTGWG------IAGTGADFVTLMQGMT--------------EAG-SGLD
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 PFGPMG------AAGEAVTSLFAVGNIVGDHGTDAMWNLAGDAGDVASVA
MMAR_5416|M.marinum_M -----------MTHASSDIADPLIMCMDG-------VKTVASHCLPGIVD
MUL_5045|M.ulcerans_Agy99 DLLAYLEPDAGLFEPDGFESDAWETQFDGFES---DVGEIEREAEAGAAD
Mb3646c|M.bovis_AF2122/97 RDILEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGA
Rv3616c|M.tuberculosis_H37Rv RDILEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGA
MLBr_00405|M.leprae_Br4923 RGILDGAKKALLFVRPVAIDLNYIPLVGSVMSASIQAQACAAAMAAVSGG
Mflv_0157|M.gilvum_PYR-GCK ATGLATSVATPIINAGLMTLTAASNTLG-FGRPEDGERFTDGARQFSEAN
TH_2666|M.thermoresistible__bu QGRLAKAAATPIIRAALLAMMVMSNTCG-VGTPEKGDRFEEGAQAFEAAG
MSMEG_0723|M.smegmatis_MC2_155 --MFPKCPQTPIIQAGLLAISAMSLQCG-LGTPDDGSRFGDGCGEFRKTD
Mvan_0656|M.vanbaalenii_PYR-1 QSMLPFAKQTLIIEGGLKMISVMEEQSGGANVPSEGESYSDSAHRFNQVG
MMAR_5416|M.marinum_M NLPTAWRRGSVICDATEYVCVGVRFLLG-DGLPDPGDRYAGSGSMFDEVS
MUL_5045|M.ulcerans_Agy99 N-PHELCPGTVVCGATLTILGVMWGWLG-DESPEQGDRLASSGSLFDDVG
* . .
Mb3646c|M.bovis_AF2122/97 LAYLAVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGILGEVWE
Rv3616c|M.tuberculosis_H37Rv LAYLVVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGTLGEVWE
MLBr_00405|M.leprae_Br4923 LAYLLVQTAIHTAKFVALLARLAHLLASAVADVVSDGVAIIKGIVDHLWH
Mflv_0157|M.gilvum_PYR-GCK DELQQAVPPPDWQGDASDAYGLRNTEQQQRAGSMATFDGQIQEVLAEEAG
TH_2666|M.thermoresistible__bu EALGATKSPESWQGKASNTYTDRNDEQRARAERMAAIDRTVKEILDAEAH
MSMEG_0723|M.smegmatis_MC2_155 ELQESAAPNEQWQGSASKAYDAQVVRQRERAQKLAQADEMMQEVIRSQAE
Mvan_0656|M.vanbaalenii_PYR-1 DTLASAMPDDRWRGTAADAYTLANEQQYARAGKLADADLKVRMALSAEAG
MMAR_5416|M.marinum_M AQVAALVPGGGWRGCAAQAYAAQSLAQSARAKMMGDLDRHTRDLVAAQSD
MUL_5045|M.ulcerans_Agy99 AQVAALGPDGGWRGNAAQAYWVQNLAQSRHATLMADLDRLTAGLVSSQAD
. * :. :
Mb3646c|M.bovis_AF2122/97 FITNALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATSGLSQ
Rv3616c|M.tuberculosis_H37Rv FITNALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATSGLSQ
MLBr_00405|M.leprae_Br4923 FIAGALTGLKDIVEKIIHWFFGLFSHWWSRLHSFFGGIPGLSGATSGLSQ
Mflv_0157|M.gilvum_PYR-GCK QVQDTRDFVSTRQVMLAAAIPAAITAKLIPPGGAAAAMAIELAAVAATVP
TH_2666|M.thermoresistible__bu QVDVARKMLDRCQTVLSLSIPAAIAAKAIPFKGPAISTAIEVAAVAGTAP
MSMEG_0723|M.smegmatis_MC2_155 QVSQTRQLLDIYSIALAAMIVPATIAMYTPY-GQPASVAIQAGAVAGTVP
Mvan_0656|M.vanbaalenii_PYR-1 EVRTARRMFNQAATVLGNAIVPALAARALGKHGKAISYGIETGAVASSMP
MMAR_5416|M.marinum_M AVTRVRSVVITAEVFVACLGVCCLALETQGPTGQAVSFFLALDLCS-VAL
MUL_5045|M.ulcerans_Agy99 AVKQARERLSVLIAVVLGVLVVCAGLELGGPEGQLPSFHIAVAACG-VVQ
: . . : . . .
Mb3646c|M.bovis_AF2122/97 VTGLFGAAGLSASSGLAHADSLASSASLPALAGIGGGSGFGGLPSLAQVH
Rv3616c|M.tuberculosis_H37Rv VTGLFGAAGLSASSGLAHADSLASSASLPALAGIGGGSGFGGLPSLAQVH
MLBr_00405|M.leprae_Br4923 VTGLFGVPGLAGSSGLLSGESLLSTENLPSLAGVGAGLGLGSLPQLAQLH
Mflv_0157|M.gilvum_PYR-GCK FA-MQRVTEMVSHSADNADRIRQIGSHYGVVDESAQMPGGLSGAQSGTPA
TH_2666|M.thermoresistible__bu LA-SLRYNELTRAVIRNAARMTQAAGEYSSVASAANPS------------
MSMEG_0723|M.smegmatis_MC2_155 LA-TGSMLAMAALANANAAKVLQATAHYTEVAGEA---------------
Mvan_0656|M.vanbaalenii_PYR-1 IC-IWHMTQLAGHSARAAETLKDAVALYEQVANEGYSVRM----------
MMAR_5416|M.marinum_M AALIGGLISLAVTTSRNASGMQDTTQCLTTMMTSLPTLAPAVAGLPDEPL
MUL_5045|M.ulcerans_Agy99 VAAAATLIGLANKTSSNASSLRAATQRATEMLAARSAGSDAIPGSAG---
: :
Mb3646c|M.bovis_AF2122/97 AASTRQALRPRADGPVGAAAEQVGGQSQLVSAQG----SQGMGGPVGMGG
Rv3616c|M.tuberculosis_H37Rv AASTRQALRPRADGPVGAAAEQVGGQSQLVSAQG----SQGMGGPVGMGG
MLBr_00405|M.leprae_Br4923 AASTRQGTRSQAGVSAELSTEQFGGQQEPVSAQG----SQGMGGSQGMGG
Mflv_0157|M.gilvum_PYR-GCK PLRVSESIRGTAGIQQNVAATIDSARSAPDGSAGDVFKTHGVVCTSTAAA
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_5416|M.marinum_M ADALADLPNDRQPIPQIPDAAVIFAQLPGLPEFSLPTAPSPGFPDFGAPH
MUL_5045|M.ulcerans_Agy99 ----------------------------------------MTAPDVGTPP
Mb3646c|M.bovis_AF2122/97 MHPSSGASKG--TTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV
Rv3616c|M.tuberculosis_H37Rv MHPSSGASKG--TTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV
MLBr_00405|M.leprae_Br4923 MTPASTKSKKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHVV
Mflv_0157|M.gilvum_PYR-GCK LKSAELARRSAAEKMHLISTDLSAKLGSSATEYSHTEQQNADAVDRQMPP
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_5416|M.marinum_M LPIPTLVGLPRQPDVFRGLRDVSSSFAGPLPTTGRLLKGGSGITGRLGHF
MUL_5045|M.ulcerans_Agy99 SGARPRLDVAGDTARIRRTPDRGAAYAELLDRS-----------------
Mb3646c|M.bovis_AF2122/97 -------------------------------
Rv3616c|M.tuberculosis_H37Rv -------------------------------
MLBr_00405|M.leprae_Br4923 -------------------------------
Mflv_0157|M.gilvum_PYR-GCK R------------------------------
TH_2666|M.thermoresistible__bu -------------------------------
MSMEG_0723|M.smegmatis_MC2_155 -------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 -------------------------------
MMAR_5416|M.marinum_M DSTAAAGTTAQERVPAGAATAPSPQPQKRVC
MUL_5045|M.ulcerans_Agy99 -------------------------------