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MALGKLWVDANYFYGVADHANMMSSDPALGSAAIATDAAILMQSLAAVGGSTMGATGLATSVATPIINAG LMTLTAASNTLGFGRPEDGERFTDGARQFSEANDELQQAVPPPDWQGDASDAYGLRNTEQQQRAGSMATF DGQIQEVLAEEAGQVQDTRDFVSTRQVMLAAAIPAAITAKLIPPGGAAAAMAIELAAVAATVPFAMQRVT EMVSHSADNADRIRQIGSHYGVVDESAQMPGGLSGAQSGTPAPLRVSESIRGTAGIQQNVAATIDSARSA PDGSAGDVFKTHGVVCTSTAAALKSAELARRSAAEKMHLISTDLSAKLGSSATEYSHTEQQNADAVDRQM PPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0157 | - | - | 100% (353) | hypothetical protein Mflv_0157 |
| M. gilvum PYR-GCK | Mflv_1605 | - | 4e-10 | 27.43% (175) | hypothetical protein Mflv_1605 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 1e-10 | 30.28% (142) | hypothetical protein Mb3894 |
| M. tuberculosis H37Rv | Rv3864 | - | 1e-10 | 30.28% (142) | hypothetical protein Rv3864 |
| M. leprae Br4923 | MLBr_00405 | - | 7e-11 | 29.20% (137) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1325 | - | 5e-16 | 24.55% (330) | hypothetical protein MMAR_1325 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0078 | - | 2e-34 | 42.86% (189) | hypothetical protein MSMEG_0078 |
| M. thermoresistible (build 8) | TH_2666 | - | 8e-37 | 39.65% (227) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_2554 | - | 4e-15 | 23.94% (330) | hypothetical protein MUL_2554 |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | 7e-23 | 30.09% (216) | hypothetical protein Mvan_0656 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0157|M.gilvum_PYR-GCK --MALGKLWVDANYFYGVADHANMMSSDP---------------------
MSMEG_0078|M.smegmatis_MC2_155 --------------------------------------------------
TH_2666|M.thermoresistible__bu ----MLDAYSTLNWGKSVVEHPMSAKDHT---------------------
Mb3894|M.bovis_AF2122/97 MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLA
Rv3864|M.tuberculosis_H37Rv MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLA
MMAR_1325|M.marinum_M MPAGLIAAAVRTIVNLGSFGQQFVGVNDP------------KFTNPEYLA
MUL_2554|M.ulcerans_Agy99 MPAGLIAAAVRTIVNLGSFGQQFVGVNDP------------KFTNPEYLA
Mvan_0656|M.vanbaalenii_PYR-1 --MGLFDFYSDLMQHVGESMQRVDPFGPMG-----------AAGEAVTSL
MLBr_00405|M.leprae_Br4923 -MSGAFIIDPTLKAIEAWHALLGIGVPNDGGVLYSSLSFFEKALEHLAAA
Mflv_0157|M.gilvum_PYR-GCK --ALGSAAIATDAAILMQSLAAVGGSTMGATGLATSVATPIINAG-----
MSMEG_0078|M.smegmatis_MC2_155 ---------------------------MGDTKLAAAAATPIIAFG-----
TH_2666|M.thermoresistible__bu --GWGIAGTGADFVTLMQGMTEAG-SGLDQGRLAKAAATPIIRAA-----
Mb3894|M.bovis_AF2122/97 IPGTNWIGQAAEAYLNQNIAQQLRAQVMG--DLDKLTGNMISNQAKYVSD
Rv3864|M.tuberculosis_H37Rv IPGTNWIGQAAEAYLNQNIAQQLRAQVMG--DLDKLTGNMISNQAKYVSD
MMAR_1325|M.marinum_M ASATGMASDGLTAVFGQTWVPQALAKRVGHSQLTSLASSKAAQGASAILW
MUL_2554|M.ulcerans_Agy99 ASATGMASDGLTAVFGQTWVPQALAKRVGHSQLTSLASSKAAQGASAILW
Mvan_0656|M.vanbaalenii_PYR-1 FAVGNIVGDHGTDAMWNLAGDAGDVASVAQSMLPFAKQTLIIEGG-----
MLBr_00405|M.leprae_Br4923 FPGDGWLGSAADKYAGQNRKRVDIFQELA--ELDKELIELIHNQANSVQT
: * .
Mflv_0157|M.gilvum_PYR-GCK -LMTLTAASNTLG--FGRPEDGERFTDGARQFSEANDELQQAVPPPDWQG
MSMEG_0078|M.smegmatis_MC2_155 -LRTMTIMSNLTG--VEGPEHGDRYGQGAEAFSGVSSGLDGTRSPDSWEG
TH_2666|M.thermoresistible__bu -LLAMMVMSNTCG--VGTPEKGDRFEEGAQAFEAAGEALGATKSPESWQG
Mb3894|M.bovis_AF2122/97 TRDVLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWELAIPMSGIAMAVVGG
Rv3864|M.tuberculosis_H37Rv TRDVLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWELAIPMSGIAMAVVGG
MMAR_1325|M.marinum_M TINIVEVLETLMG--FGPPAEGDELLVGSTQFAKAQAQLGSALPDNSWQG
MUL_2554|M.ulcerans_Agy99 TINIVEVLETLMG--FGPPAEGDELLVGSTQFAKAQAQLGSALPDNSWQG
Mvan_0656|M.vanbaalenii_PYR-1 -LKMISVMEEQSGG-ANVPSEGESYSDSAHRFNQVGDTLASAMPDDRWRG
MLBr_00405|M.leprae_Br4923 TRGILDGAKKALLFVRPVAIDLNYIPLVGSVMSASIQAQACAAAMAAVSG
: . : . . *
Mflv_0157|M.gilvum_PYR-GCK DASDAYGLRNTEQQQRAGSMATFDGQIQEVLA--------EEAGQVQDTR
MSMEG_0078|M.smegmatis_MC2_155 SSSDAYSDRNREQKERAALMAETDRVVKEVLD--------KEAGEIEDTR
TH_2666|M.thermoresistible__bu KASNTYTDRNDEQRARAERMAAIDRTVKEILD--------AEAHQVDVAR
Mb3894|M.bovis_AF2122/97 ALLYLTIMTLMNATNLRGILGRLIEMLTTLPK------FPGLPGLPSLPD
Rv3864|M.tuberculosis_H37Rv ALLYLTIMTLMNATNLRGILGRLIEMLTTLPK------FPGLPGLPSLPD
MMAR_1325|M.marinum_M SASYAYASQNTALQNRGQALAELDVKFAALVKDQAEWVTHGRLGIAILKN
MUL_2554|M.ulcerans_Agy99 SASYAYASQNTALQNRGQALAELDVKFAALVKDQAEWATHGRLGIAILKN
Mvan_0656|M.vanbaalenii_PYR-1 TAADAYTLANEQQYARAGKLADADLKVRMALS--------AEAGEVRTAR
MLBr_00405|M.leprae_Br4923 GLAYLLVQTAIHTAKFVALLARLAHLLASAVAD------VVSDGVAIIKG
:. .
Mflv_0157|M.gilvum_PYR-GCK DFVSTRQVMLAAAIPAAITAKLI--PPG-GAAAAMAIELAAVAATVPFA-
MSMEG_0078|M.smegmatis_MC2_155 RQIDHQMTELTWLIPAAIAAKFWNAPPGSGEIASQIIQWGGVAKTLPIA-
TH_2666|M.thermoresistible__bu KMLDRCQTVLSLSIPAAIAAKAI---PFKGPAISTAIEVAAVAGTAPLA-
Mb3894|M.bovis_AF2122/97 IIDGLWPPKLP-DIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFPG
Rv3864|M.tuberculosis_H37Rv IIDGLWPPKLP-DIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFP-
MMAR_1325|M.marinum_M LLLAAFAVEMALMFAVPAGPAMARSFGFTVSGLGIAIAMGLLSTVLTYSV
MUL_2554|M.ulcerans_Agy99 LLLATFAVEMALMFAVPAGPAMARSFGFTVSGLGIAIAMGLLSTVLTYSV
Mvan_0656|M.vanbaalenii_PYR-1 RMFNQAATVLGNAIVPALAARALG---KHGKAISYGIETGAVASSMPIC-
MLBr_00405|M.leprae_Br4923 IVDHLWHFIAGALTGLKDIVEKIIHWFFGLFSHWWSRLHSFFGGIPGLSG
.
Mflv_0157|M.gilvum_PYR-GCK ---------------------------MQRVTEMVSHSADNADRIRQIG-
MSMEG_0078|M.smegmatis_MC2_155 ---------------------------TQRMYRMIADSSENATLIRRAG-
TH_2666|M.thermoresistible__bu ---------------------------SLRYNELTRAVIRNAARMTQAA-
Mb3894|M.bovis_AF2122/97 FPSLPGFPGLPGFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVG-
Rv3864|M.tuberculosis_H37Rv -----------GFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVG-
MMAR_1325|M.marinum_M ENSKKADVLTANYQDLTPDPYQGADPSMPVAANMPASAESTISSFAASGT
MUL_2554|M.ulcerans_Agy99 ENSKKADVLTANYQDLTPDPYQGADPSMPMAANMPASAESTISSFAASGT
Mvan_0656|M.vanbaalenii_PYR-1 ---------------------------IWHMTQLAGHSARAAETLKDAV-
MLBr_00405|M.leprae_Br4923 -----------------------ATSGLSQVTGLFGVPGLAGSSGLLSG-
:
Mflv_0157|M.gilvum_PYR-GCK -------SHYGVVDESAQMPGGLSGAQSG--TPAPLRVSESIRGTAGIQQ
MSMEG_0078|M.smegmatis_MC2_155 -------ATYDRIAAEAQAQ------------------------------
TH_2666|M.thermoresistible__bu -------GEYSSVASAANPS------------------------------
Mb3894|M.bovis_AF2122/97 -----DLGKLPTWTELAALPDFLGGFAG--LPSLGFGNLLSFASLPTVGQ
Rv3864|M.tuberculosis_H37Rv -----DLGKLPTWTELAALPDFLGGFAG--LPSLGFGNLLSFASLPTVGQ
MMAR_1325|M.marinum_M AFTAEAAGSLGRASGAADESAFYSAAADEAVPLEDAPSATSAFTMPTLAQ
MUL_2554|M.ulcerans_Agy99 AFTAEAAGSLGRASGAADESAFYSAAADEAVPLEDAPSATSAFTMPTLAQ
Mvan_0656|M.vanbaalenii_PYR-1 -------ALYEQVANEGYSVRM----------------------------
MLBr_00405|M.leprae_Br4923 -------ESLLSTENLPSLAGVGAGLGLGSLPQLAQLHAASTRQGTRSQA
Mflv_0157|M.gilvum_PYR-GCK NVAATIDSARSAPDGSAGDVFKTHGVVCTSTAAALKSAELARRSAAEKMH
MSMEG_0078|M.smegmatis_MC2_155 --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
Mb3894|M.bovis_AF2122/97 VTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQAQQG-----GQQHAT
Rv3864|M.tuberculosis_H37Rv VTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQAQQG-----GQQHAT
MMAR_1325|M.marinum_M LMAISGQGAKFSGHVSQHANLANQAMGQVQQVASMAQQGKGTAPAEDTAQ
MUL_2554|M.ulcerans_Agy99 LMAISGQGAKFSGHVSQHANLANQAMGQVQQVASMAQQGKGTAPAEDTAQ
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_00405|M.leprae_Br4923 GVSAELSTEQFGGQQEPVSAQGSQGMGGSQGMGGMTPAS--------TKS
Mflv_0157|M.gilvum_PYR-GCK LISTDLSAKLGSSATEYSHTEQQNADAVDRQMPPR-----------
MSMEG_0078|M.smegmatis_MC2_155 ----------------------------------------------
TH_2666|M.thermoresistible__bu ----------------------------------------------
Mb3894|M.bovis_AF2122/97 LVSDKKEDEEGA--AAGVAEAERAPIDAGTAASQRGQEGTVL----
Rv3864|M.tuberculosis_H37Rv LVSDKKEDEE------GVAEAERAPIDAGTAASQRGQEGTVL----
MMAR_1325|M.marinum_M AEATTVEDVEGAGADSAGAAAGRAPIEAAAADTPPAQQPIFAQQVV
MUL_2554|M.ulcerans_Agy99 TEATTVEDVEGAGADSAGAAAGRAPIEAAAADTPPAQQPIFAQQVV
Mvan_0656|M.vanbaalenii_PYR-1 ----------------------------------------------
MLBr_00405|M.leprae_Br4923 KKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHVV----