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MSGAFIIDPTLKAIEAWHALLGIGVPNDGGVLYSSLSFFEKALEHLAAAFPGDGWLGSAADKYAGQNRKR VDIFQELAELDKELIELIHNQANSVQTTRGILDGAKKALLFVRPVAIDLNYIPLVGSVMSASIQAQACAA AMAAVSGGLAYLLVQTAIHTAKFVALLARLAHLLASAVADVVSDGVAIIKGIVDHLWHFIAGALTGLKDI VEKIIHWFFGLFSHWWSRLHSFFGGIPGLSGATSGLSQVTGLFGVPGLAGSSGLLSGESLLSTENLPSLA GVGAGLGLGSLPQLAQLHAASTRQGTRSQAGVSAELSTEQFGGQQEPVSAQGSQGMGGSQGMGGMTPAST KSKKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00405 | - | - | 100% (394) | hypothetical protein MLBr_00405 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3646c | - | 1e-139 | 62.94% (394) | hypothetical protein Mb3646c |
| M. gilvum PYR-GCK | Mflv_0157 | - | 2e-10 | 29.20% (137) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3616c | - | 1e-139 | 62.69% (394) | hypothetical protein Rv3616c |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-06 | 28.45% (116) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4166 | espA | 1e-116 | 57.44% (390) | ESX-1 secretion-associated protein A, EspA |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0723 | - | 6e-13 | 32.34% (167) | hypothetical protein MSMEG_0723 |
| M. thermoresistible (build 8) | TH_2666 | - | 2e-10 | 27.66% (141) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_2554 | - | 2e-12 | 24.87% (378) | hypothetical protein MUL_2554 |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | 2e-07 | 27.06% (170) | hypothetical protein Mvan_0656 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0157|M.gilvum_PYR-GCK -----MALGKLWVDANYFYGVADHANMMSSDPALGSAAIATDAAILMQSL
TH_2666|M.thermoresistible__bu -------MLDAYSTLNWGKSVVEHPMSAKDHTGWGIAGTGADFVTLMQGM
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 -------MGLFDFYSDLMQHVGESMQRVDPFGPMGAAGEAVTSLFAVGNI
Mb3646c|M.bovis_AF2122/97 --------------------------------------------------
Rv3616c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4166|M.marinum_M --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MUL_2554|M.ulcerans_Agy99 -MPAGLIAAAVRTIVNLGSFGQQFVGVNDPKFTNPEYLAASATGMASDGL
MAB_4284c|M.abscessus_ATCC_199 MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAE
Mflv_0157|M.gilvum_PYR-GCK A--------------AVGGSTMGATGLATSVA----TPIINAGLMTLTAA
TH_2666|M.thermoresistible__bu T--------------EAG-SGLDQGRLAKAAA----TPIIRAALLAMMVM
MSMEG_0723|M.smegmatis_MC2_155 -------------------------MFPKCPQ----TPIIQAGLLAISAM
Mvan_0656|M.vanbaalenii_PYR-1 VGDHGTDAMWNLAGDAGDVASVAQSMLPFAKQ----TLIIEGGLKMISVM
Mb3646c|M.bovis_AF2122/97 -----------------------------MSR----AFIIDPTISAIDGL
Rv3616c|M.tuberculosis_H37Rv -----------------------------MSR----AFIIDPTISAIDGL
MMAR_4166|M.marinum_M -----------------------------MSR----AFIIDPTISAINGL
MLBr_00405|M.leprae_Br4923 -----------------------------MSG----AFIIDPTLKAIEAW
MUL_2554|M.ulcerans_Agy99 TAVFGQTWVPQALAKRVGHSQLTSLASSKAAQG---ASAILWTINIVEVL
MAB_4284c|M.abscessus_ATCC_199 SVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN
. : :
Mflv_0157|M.gilvum_PYR-GCK SNTLG----------------FGRPEDGERFTDGARQFSEANDELQQAVP
TH_2666|M.thermoresistible__bu SNTCG----------------VGTPEKGDRFEEGAQAFEAAGEALGATKS
MSMEG_0723|M.smegmatis_MC2_155 SLQCG----------------LGTPDDGSRFGDGCGEFRKTDELQESAAP
Mvan_0656|M.vanbaalenii_PYR-1 EEQSGG---------------ANVPSEGESYSDSAHRFNQVGDTLASAMP
Mb3646c|M.bovis_AF2122/97 YDLLG----------------IGIPNQGGILYSSLEYFEKALEELAAAFP
Rv3616c|M.tuberculosis_H37Rv YDLLG----------------IGIPNQGGILYSSLEYFEKALEELAAAFP
MMAR_4166|M.marinum_M HALLG----------------IGLPEDGGIIDSALSFFGKALDDLGSAFP
MLBr_00405|M.leprae_Br4923 HALLG----------------IGVPNDGGVLYSSLSFFEKALEHLAAAFP
MUL_2554|M.ulcerans_Agy99 ETLMG----------------FGPPAEGDELLVGSTQFAKAQAQLGSALP
MAB_4284c|M.abscessus_ATCC_199 DFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNR
* . :
Mflv_0157|M.gilvum_PYR-GCK PPDWQGDASDAYGLRNTEQQQRAGSMATFDGQIQEVLAEEAGQVQDTRDF
TH_2666|M.thermoresistible__bu PESWQGKASNTYTDRNDEQRARAERMAAIDRTVKEILDAEAHQVDVARKM
MSMEG_0723|M.smegmatis_MC2_155 NEQWQGSASKAYDAQVVRQRERAQKLAQADEMMQEVIRSQAEQVSQTRQL
Mvan_0656|M.vanbaalenii_PYR-1 DDRWRGTAADAYTLANEQQYARAGKLADADLKVRMALSAEAGEVRTARRM
Mb3646c|M.bovis_AF2122/97 GDGWLGSAADKYAGKNRNHVNFFQELADLDRQLISLIHDQANAVQTTRDI
Rv3616c|M.tuberculosis_H37Rv GDGWLGSAADKYAGKNRNHVNFFQELADLDRQLISLIHDQANAVQTTRDI
MMAR_4166|M.marinum_M GDGWLGSAADHYSGKNRKHVNFFKELAELDRELQKLIADQASAVKTTREI
MLBr_00405|M.leprae_Br4923 GDGWLGSAADKYAGQNRKRVDIFQELAELDKELIELIHNQANSVQTTRGI
MUL_2554|M.ulcerans_Agy99 DNSWQGSASYAYASQNTALQNRGQALAELDVKFAALVKDQAEWATHGRLG
MAB_4284c|M.abscessus_ATCC_199 DTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVD
* .: : : . :*
Mflv_0157|M.gilvum_PYR-GCK VSTRQVMLAAAIPAAITAKLIPPGGAAAAMAIELAAVAATVPFAMQRVTE
TH_2666|M.thermoresistible__bu LDRCQTVLSLSIPAAIAAKAIPFKGPAISTAIEVAAVAGTAPLASLRYNE
MSMEG_0723|M.smegmatis_MC2_155 LDIYSIALAAMIVPATIAMYTPY-GQPASVAIQAGAVAGTVPLATGSMLA
Mvan_0656|M.vanbaalenii_PYR-1 FNQAATVLGNAIVPALAARALGKHGKAISYGIETGAVASSMPICIWHMTQ
Mb3646c|M.bovis_AF2122/97 LEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGALAY
Rv3616c|M.tuberculosis_H37Rv LEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGALAY
MMAR_4166|M.marinum_M LEDAKKGLEFVRPVAVDLTYIPIVGWAMSAAFQAPVCAAAMAVVGGALAY
MLBr_00405|M.leprae_Br4923 LDGAKKALLFVRPVAIDLNYIPLVGSVMSASIQAQACAAAMAAVSGGLAY
MUL_2554|M.ulcerans_Agy99 IAILKNLLLATFAVEMALMFAVPAGPAMARSFGFTVSGLGIAIAMGLLST
MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTN
.
Mflv_0157|M.gilvum_PYR-GCK MVSHSADNADRIRQIGSHYGVVDESAQMPGGLSGAQSGTPAPLRVSESIR
TH_2666|M.thermoresistible__bu LTRAVIRNAARMTQAAGEYSSVASAANPS---------------------
MSMEG_0723|M.smegmatis_MC2_155 MAALANANAAKVLQATAHYTEVAGEA------------------------
Mvan_0656|M.vanbaalenii_PYR-1 LAGHSARAAETLKDAVALYEQVANEGYSVRM-------------------
Mb3646c|M.bovis_AF2122/97 LAVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGILGEVWEFIT
Rv3616c|M.tuberculosis_H37Rv LVVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGTLGEVWEFIT
MMAR_4166|M.marinum_M LVVKTLINSMKLVSLLAQLAKLLAEAVADVVSDVVDIIKGILEEVWEFLT
MLBr_00405|M.leprae_Br4923 LLVQTAIHTAKFVALLARLAHLLASAVADVVSDGVAIIKGIVDHLWHFIA
MUL_2554|M.ulcerans_Agy99 VLTYSVENSKKADVLTANYQDLTPDPYQGADPSMPMAAN-MPASAESTIS
MAB_4284c|M.abscessus_ATCC_199 IGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLAGNAGLA
: : .
Mflv_0157|M.gilvum_PYR-GCK GTAGIQQNVAATIDSARS------------------APDGSAG-----DV
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 NALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATS-----GL
Rv3616c|M.tuberculosis_H37Rv NALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATS-----GL
MMAR_4166|M.marinum_M HPFEFLKDLLNKLVSWASSLLSQWGSKLQSFFGGIPGLSGMGG-----GL
MLBr_00405|M.leprae_Br4923 GALTGLKDIVEKIIHWFFGLFSHWWSRLHSFFGGIPGLSGATS-----GL
MUL_2554|M.ulcerans_Agy99 SFAASGTAFTAEAAG----------------------SLGRAS-----GA
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN
Mflv_0157|M.gilvum_PYR-GCK FKTHGVVCTSTAAALKS-AELARRSAAEKMHLISTDLSAKLGSSATEYSH
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 SQVTGLFGAAGLSASSG---LAHADSLASSASLPALAGIGGGSGFGGLPS
Rv3616c|M.tuberculosis_H37Rv SQVTGLFGAAGLSASSG---LAHADSLASSASLPALAGIGGGSGFGGLPS
MMAR_4166|M.marinum_M SQLTSFFSSAGAAGSAGSVGAADSASLVSSAGLPGGLGLGGGSGFGSMPN
MLBr_00405|M.leprae_Br4923 SQVTGLFGVPGLAGSSG---LLSGESLLSTENLPSLAGVGAGLGLGSLPQ
MUL_2554|M.ulcerans_Agy99 ADESAFYSAAADEAVPLEDAPSATSAFTMPTLAQLMAISGQGAKFSGHVS
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
Mflv_0157|M.gilvum_PYR-GCK TEQQNADAVDRQMPPR----------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 LAQVHAASTRQALRPRADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMG
Rv3616c|M.tuberculosis_H37Rv LAQVHAASTRQALRPRADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMG
MMAR_4166|M.marinum_M VAQLRSAATRQDPRLTSEGPTRVSSEPVGEHAQAASAQGGQGMG------
MLBr_00405|M.leprae_Br4923 LAQLHAASTRQGTRSQAGVSAELSTEQFGGQQEPVSAQGSQGMGGSQGMG
MUL_2554|M.ulcerans_Agy99 QHANLANQAMGQVQQVASMAQQGKGTAPAEDTAQTEATTVEDVEG-----
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVG
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 GMHPSSGASK--GTTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNV
Rv3616c|M.tuberculosis_H37Rv GMHPSSGASK--GTTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNV
MMAR_4166|M.marinum_M GMHPASAGSK--GATSKKYSEGAAAGTEDAERAPVEVGVGAAARIAERRA
MLBr_00405|M.leprae_Br4923 GMTPASTKSKKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHV
MUL_2554|M.ulcerans_Agy99 ---------------AGADSAGAAAGRAPIEAAAADTPPAQQPIFAQQVV
MAB_4284c|M.abscessus_ATCC_199 GAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLG
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 V-------------------------------------------------
Rv3616c|M.tuberculosis_H37Rv V-------------------------------------------------
MMAR_4166|M.marinum_M G-------------------------------------------------
MLBr_00405|M.leprae_Br4923 V-------------------------------------------------
MUL_2554|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGS
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 --------------------------------------------------
Rv3616c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4166|M.marinum_M --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MUL_2554|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAH
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3646c|M.bovis_AF2122/97 --------------------------------------------------
Rv3616c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4166|M.marinum_M --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MUL_2554|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFG
Mflv_0157|M.gilvum_PYR-GCK -------------------------------------
TH_2666|M.thermoresistible__bu -------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 -------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 -------------------------------------
Mb3646c|M.bovis_AF2122/97 -------------------------------------
Rv3616c|M.tuberculosis_H37Rv -------------------------------------
MMAR_4166|M.marinum_M -------------------------------------
MLBr_00405|M.leprae_Br4923 -------------------------------------
MUL_2554|M.ulcerans_Agy99 -------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH