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HPDEAATHNRSFEDLLAYLEPDAGLFEPDGFESDAWETQFDGFESDVGEIEREAEAGAADNPHELCPGTV VCGATLTILGVMWGWLGDESPEQGDRLASSGSLFDDVGAQVAALGPDGGWRGNAAQAYWVQNLAQSRHAT LMADLDRLTAGLVSSQADAVKQARERLSVLIAVVLGVLVVCAGLELGGPEGQLPSFHIAVAACGVVQVAA AATLIGLANKTSSNASSLRAATQRATEMLAARSAGSDAIPGSAGMTAPDVGTPPSGARPRLDVAGDTARI RRTPDRGAAYAELLDRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_5045 | - | - | 100% (298) | hypothetical protein MUL_5045 |
| M. ulcerans Agy99 | MUL_2554 | - | 1e-13 | 26.52% (230) | hypothetical protein MUL_2554 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 8e-22 | 33.33% (192) | hypothetical protein Mb3894 |
| M. gilvum PYR-GCK | Mflv_0157 | - | 4e-09 | 21.68% (226) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3864 | - | 8e-22 | 33.33% (192) | hypothetical protein Rv3864 |
| M. leprae Br4923 | MLBr_00405 | - | 3e-10 | 28.25% (177) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5454 | - | 1e-154 | 91.28% (298) | hypothetical protein MMAR_5454 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0723 | - | 3e-13 | 26.59% (173) | hypothetical protein MSMEG_0723 |
| M. thermoresistible (build 8) | TH_2666 | - | 3e-09 | 25.63% (199) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | 6e-10 | 24.14% (232) | hypothetical protein Mvan_0656 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0157|M.gilvum_PYR-GCK ---------------------------MALGKLWVDANYFYGVADHANMM
TH_2666|M.thermoresistible__bu -----------------------------MLDAYSTLNWGKSVVEHPMSA
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 -----------------------------MGLFDFYSDLMQHVGESMQRV
MUL_5045|M.ulcerans_Agy99 ------------------------MHPDEAATHNR------SFEDLLAYL
MMAR_5454|M.marinum_M ------------------------MHPDEAATYDR------MLDDLLNRF
Mb3894|M.bovis_AF2122/97 MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLA
Rv3864|M.tuberculosis_H37Rv MASGSGLCKTTSNFIWGQLLLLGEGIPDPGDIFNTGSSLFKQISDKMGLA
MLBr_00405|M.leprae_Br4923 -MSGAFIIDPTLKAIEAWHALLGIGVPNDGGVLYSSLSFFEKALEHLAAA
Mflv_0157|M.gilvum_PYR-GCK SSDPALG--SAAIATDAAILMQSLA--------------AVGGSTMGATG
TH_2666|M.thermoresistible__bu KDHTGWG--IAGTGADFVTLMQGMT--------------EAG-SGLDQGR
MSMEG_0723|M.smegmatis_MC2_155 -------------------------------------------------M
Mvan_0656|M.vanbaalenii_PYR-1 DPFGPMG--AAGEAVTSLFAVGNIVGDHGTDAMWNLAGDAGDVASVAQSM
MUL_5045|M.ulcerans_Agy99 EP-------DAGLFEPDGFESDAWETQFDGFESDVGEIEREAEAGAADNP
MMAR_5454|M.marinum_M AP-------DAGPFEPDGFESDAWETQFDGFESDAGEIEREAEAGAADNP
Mb3894|M.bovis_AF2122/97 IPGTNWIGQAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTR
Rv3864|M.tuberculosis_H37Rv IPGTNWIGQAAEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTR
MLBr_00405|M.leprae_Br4923 FPGDGWLGSAADKYAGQNRKRVDIFQELAELDKELIELIHNQANSVQTTR
Mflv_0157|M.gilvum_PYR-GCK LATSVATPIIN---------AGLMTLTAASNTLG-FGRPEDGERFTDGAR
TH_2666|M.thermoresistible__bu LAKAAATPIIR---------AALLAMMVMSNTCG-VGTPEKGDRFEEGAQ
MSMEG_0723|M.smegmatis_MC2_155 FPKCPQTPIIQ---------AGLLAISAMSLQCG-LGTPDDGSRFGDGCG
Mvan_0656|M.vanbaalenii_PYR-1 LPFAKQTLIIE---------GGLKMISVMEEQSGGANVPSEGESYSDSAH
MUL_5045|M.ulcerans_Agy99 HELCPGTVVCG---------ATLTILGVMWGWLG-DESPEQGDRLASSGS
MMAR_5454|M.marinum_M HELCRGTVVCA---------STLTILGVMWGWLG-DSPPEQGDRLASSGS
Mb3894|M.bovis_AF2122/97 DVLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWEL-AIPMSGIAMAVVGGA
Rv3864|M.tuberculosis_H37Rv DVLRAMKKMIDGVYKVCKGLEKIPLLGHLWSWEL-AIPMSGIAMAVVGGA
MLBr_00405|M.leprae_Br4923 GILDGAKKALLFVRPVAIDLNYIPLVGSVMSASIQAQACAAAMAAVSGGL
. : : .
Mflv_0157|M.gilvum_PYR-GCK QFSEANDELQQAVPPPDWQG----------------------DASDAYGL
TH_2666|M.thermoresistible__bu AFEAAGEALGATKSPESWQG----------------------KASNTYTD
MSMEG_0723|M.smegmatis_MC2_155 EFRKTDELQESAAPNEQWQG----------------------SASKAYDA
Mvan_0656|M.vanbaalenii_PYR-1 RFNQVGDTLASAMPDDRWRG----------------------TAADAYTL
MUL_5045|M.ulcerans_Agy99 LFDDVGAQVAALGPDGGWRG----------------------NAAQAYWV
MMAR_5454|M.marinum_M LFDDVGAQVAALDPDGGWRG----------------------NAAQAYWV
Mb3894|M.bovis_AF2122/97 LLYLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWP
Rv3864|M.tuberculosis_H37Rv LLYLTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWP
MLBr_00405|M.leprae_Br4923 AYLLVQTAIHTAKFVALLAR----------------LAHLLASAVADVVS
.
Mflv_0157|M.gilvum_PYR-GCK RNTEQQ-------------------QRAGSMATFDGQIQ-----------
TH_2666|M.thermoresistible__bu RNDEQR-------------------ARAERMAAIDRTVK-----------
MSMEG_0723|M.smegmatis_MC2_155 QVVRQR-------------------ERAQKLAQADEMMQ-----------
Mvan_0656|M.vanbaalenii_PYR-1 ANEQQY-------------------ARAGKLADADLKVR-----------
MUL_5045|M.ulcerans_Agy99 QNLAQS-------------------RHATLMADLDRLT------------
MMAR_5454|M.marinum_M QNLAQS-------------------RHATLMAELDRLT------------
Mb3894|M.bovis_AF2122/97 PKLPDIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFPGFPSLPGFP
Rv3864|M.tuberculosis_H37Rv PKLPDIPIPGLPDIPGLPDFKWPPTPGSPLFPDLPSFPGFP---------
MLBr_00405|M.leprae_Br4923 DGVAIIKG----------IVDHLWHFIAGALTGLKDIVEKIIHWFFG---
: :.
Mflv_0157|M.gilvum_PYR-GCK ---EVLAEEAGQVQDTRDFVSTRQVMLAAAIPAAITAKLIPPGGAAAAMA
TH_2666|M.thermoresistible__bu ---EILDAEAHQVDVARKMLDRCQTVLSLSIPAAIAAKAIPFKGPAISTA
MSMEG_0723|M.smegmatis_MC2_155 ---EVIRSQAEQVSQTRQLLDIYSIALAAMIVPATIAMYTPY-GQPASVA
Mvan_0656|M.vanbaalenii_PYR-1 ---MALSAEAGEVRTARRMFNQAATVLGNAIVPALAARALGKHGKAISYG
MUL_5045|M.ulcerans_Agy99 --AGLVSSQADAVKQARERLSVLIAVVLGVLVVCAGLELGGPEGQLPSFH
MMAR_5454|M.marinum_M --AGLVSSQADAVKQARERLSVLIAVVLGVLMVCAGLELGGPEGQLPSFH
Mb3894|M.bovis_AF2122/97 GLPGFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDLGKLPTWT
Rv3864|M.tuberculosis_H37Rv ---GFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDLGKLPTWT
MLBr_00405|M.leprae_Br4923 -LFSHWWSRLHSFFGGIPGLSGATSGLSQVTGLFGVPGLAGSSGLLSGES
. . *
Mflv_0157|M.gilvum_PYR-GCK IELAA--------------VAATVPFAMQRVTEMVSHSADNADRIRQIGS
TH_2666|M.thermoresistible__bu IEVAA--------------VAGTAPLASLRYNELTRAVIRNAARMTQAAG
MSMEG_0723|M.smegmatis_MC2_155 IQAGA--------------VAGTVPLATGSMLAMAALANANAAKVLQATA
Mvan_0656|M.vanbaalenii_PYR-1 IETGA--------------VASSMPICIWHMTQLAGHSARAAETLKDAVA
MUL_5045|M.ulcerans_Agy99 IAVAA--------------CGVVQVAAAATLIGLANKTSSNASSLRAATQ
MMAR_5454|M.marinum_M IAVAA--------------CGVVQVAAAATLIGLANKTSSNASSLRAATQ
Mb3894|M.bovis_AF2122/97 ELAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVTATMGQLQQLVAAGG
Rv3864|M.tuberculosis_H37Rv ELAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVTATMGQLQQLVAAGG
MLBr_00405|M.leprae_Br4923 LLSTEN---------LPSLAGVGAGLGLGSLPQLAQLHAASTRQGTRSQA
. .
Mflv_0157|M.gilvum_PYR-GCK HYGVVDESAQMPGGLSGAQSGTPAPLRVSESIRGTAGIQQNVAATIDSAR
TH_2666|M.thermoresistible__bu EYSSVASAANPS--------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 HYTEVAGEA-----------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 LYEQVANEGYSVRM------------------------------------
MUL_5045|M.ulcerans_Agy99 RATEMLAARSAGSDAIPGSAGMTAPDVGTPPSGARPRLD--VAGDTARIR
MMAR_5454|M.marinum_M RATEMLAARSARLDAIPGPAGMTAPDVGTPPSGARPRLD--VAGNTARSR
Mb3894|M.bovis_AF2122/97 GPSQLASMGSQQAQLISSQAQQGGQQHATLVSDKKEDEEGAAAGVAEAER
Rv3864|M.tuberculosis_H37Rv GPSQLASMGSQQAQLISSQAQQGGQQHATLVSDKKEDEE----GVAEAER
MLBr_00405|M.leprae_Br4923 GVSAELSTEQFGGQQEPVSAQGSQGMGGSQGMGGMTPASTKSKKDERKKK
Mflv_0157|M.gilvum_PYR-GCK SAPDGSAGDVFKTHGVVCTSTAAALKSAELARRSAAEKMHLISTDLSAKL
TH_2666|M.thermoresistible__bu --------------------------------------------------
MSMEG_0723|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_5045|M.ulcerans_Agy99 RTPDRGAAYAELLDRS----------------------------------
MMAR_5454|M.marinum_M RTPDRGAAFAELSDRS----------------------------------
Mb3894|M.bovis_AF2122/97 APIDAGTAASQRGQEGTVL-------------------------------
Rv3864|M.tuberculosis_H37Rv APIDAGTAASQRGQEGTVL-------------------------------
MLBr_00405|M.leprae_Br4923 KYSEGAAAGTDDAERAPIEVQSGGGKRALAQHVV----------------
Mflv_0157|M.gilvum_PYR-GCK GSSATEYSHTEQQNADAVDRQMPPR
TH_2666|M.thermoresistible__bu -------------------------
MSMEG_0723|M.smegmatis_MC2_155 -------------------------
Mvan_0656|M.vanbaalenii_PYR-1 -------------------------
MUL_5045|M.ulcerans_Agy99 -------------------------
MMAR_5454|M.marinum_M -------------------------
Mb3894|M.bovis_AF2122/97 -------------------------
Rv3864|M.tuberculosis_H37Rv -------------------------
MLBr_00405|M.leprae_Br4923 -------------------------