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MSAAVPPPGLPLTFSGGDALVTGAASGIGAAIARTLVSAGVRTIGVDLRAPEPDPDHPAHLQPGVAVDVR DPDLTARLTEAGSAPENLAYLVNCAGVLDNTGFAGVGREMWMRCLDINLVGAYNTIDALSPFLRNASPAA VVNITSIEAARVIALSNPDPTPQYAASKAGLQMLTQTAARALAADGVRVNSVSPGFVATPMAAAHGDTTD LPPALAPRVPAGRFAEPADIANAVAFLLSDQAGYITGSDLRVDGGFQLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0609 | - | - | 100% (259) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_0614 | - | 6e-31 | 37.45% (251) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 3e-28 | 34.85% (241) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2025 | fabG3 | 4e-28 | 34.57% (243) | 20-beta-hydroxysteroid dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0943 | - | 9e-29 | 33.96% (268) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2002 | fabG3 | 5e-28 | 34.57% (243) | 20-beta-hydroxysteroid dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-23 | 31.50% (254) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 2e-27 | 35.20% (250) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4715 | - | 6e-32 | 37.92% (240) | 3-oxoacyl- |
| M. avium 104 | MAV_0942 | - | 1e-28 | 34.85% (241) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_3825 | - | 1e-102 | 71.65% (254) | 3-oxoacyl- |
| M. thermoresistible (build 8) | TH_3102 | - | 3e-29 | 35.68% (241) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 6e-31 | 37.08% (240) | 3-oxoacyl- |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104 ----------MK----------TAVVTGGGSGIGLAVVERLRADGLNVAS
TH_3102|M.thermoresistible__bu ----------LK----------NAVVTGGGSGIGQAVAARLRADGYHVAT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
Mb2025|M.bovis_AF2122/97 ----------MSGR----LIGKVALVSGGARGMGASHVRAMVAEGAKVVF
Rv2002|M.tuberculosis_H37Rv ----------MSGR----LIGKVALVSGGARGMGASHVRAMVAEGAKVVF
MAB_4680c|M.abscessus_ATCC_199 ----------MNGNS-ALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
Mflv_0943|M.gilvum_PYR-GCK -MSSTIVAPSVDATPIQDLAGKTAIITGGSKGIGAATVARFVRGGARVVT
Mvan_0609|M.vanbaalenii_PYR-1 -----MSAAVPPPGLPLTFSGGDALVTGAASGIGAAIARTLVSAGVRTIG
MSMEG_3825|M.smegmatis_MC2_155 MTVAAQTGQAPTKSLAYTFTGGDAVVTGAASGIGAATAAMLMSAGIRTIR
:::*. *:* : : * .
MMAR_4715|M.marinum_M LDLK----------TPDGELAFSADVTNRSQVDAALTAIRQRLGPVTILV
MUL_0315|M.ulcerans_Agy99 LDLK----------TPDGGLAFSADVTNRSQVDAALAAIRQRLGPVTILV
MAV_0942|M.avium_104 IDLR----------PSDAELAFTADVTDRSQVDAALSAIRAQLGPVTVLV
TH_3102|M.thermoresistible__bu IDLK----------PGDDEFSHAADVTDRAQVDAAFDAIRTQLGPVTILV
MLBr_01807|M.leprae_Br4923 THRAS--------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
Mb2025|M.bovis_AF2122/97 GDILDEEGKAVAAELADAARYVHLDVTQPAQWTAAVDTAVTAFGGLHVLV
Rv2002|M.tuberculosis_H37Rv GDILDEEGKAVAAELADAARYVHLDVTQPAQWTAAVDTAVTAFGGLHVLV
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAELGDAARFTHLDVTDAEQWRELIDTTLAGFGTITGLV
Mflv_0943|M.gilvum_PYR-GCK SGRSTPG------PLPDGVEYVVADVATVDGVEHLARRAQQILGDIDIVV
Mvan_0609|M.vanbaalenii_PYR-1 VDLRAPEPD--PDHPAHLQPGVAVDVRDPD-LTARLTEAGSAPENLAYLV
MSMEG_3825|M.smegmatis_MC2_155 LDIRTPEPD--PGFGADLQVCCAADVRDPD-LLTTLRGQGAPVDTVSYVV
. ** : :*
MMAR_4715|M.marinum_M NAAGLDGFKR--FSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWGR
MUL_0315|M.ulcerans_Agy99 NAAGLDGFKR--FSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWGR
MAV_0942|M.avium_104 NAAGLDGFKK--FNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAGWGR
TH_3102|M.thermoresistible__bu NAAGLDLFRR--FTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAGWGR
MLBr_01807|M.leprae_Br4923 ANAGITSDML--IMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGR
Mb2025|M.bovis_AF2122/97 NNAGILNIGT--IEDYALTEWQRILDVNLTGVFLGIRAVVKPMKEAGRGS
Rv2002|M.tuberculosis_H37Rv NNAGILNIGT--IEDYALTEWQRILDVNLTGVFLGIRAVVKPMKEAGRGS
MAB_4680c|M.abscessus_ATCC_199 NNAGISSAAM--VADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCGS
Mflv_0943|M.gilvum_PYR-GCK NNAGATTLSLGGVLGITDADWRKDLDINFLAAVRLNAALLPAMYTRGAGS
Mvan_0609|M.vanbaalenii_PYR-1 NCAGVLDNTG--FAGVGREMWMRCLDINLVGAYNTIDALSPFLRNASPAA
MSMEG_3825|M.smegmatis_MC2_155 NCAGVIDDTG--FAGVSREHWLRCLEINLMGAYNVLDAFTPVLRQNPPAA
** . : : :::*: .. : .
MMAR_4715|M.marinum_M IVNIS-----SSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVN
MUL_0315|M.ulcerans_Agy99 IVNIS-----SSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVN
MAV_0942|M.avium_104 IVNIS-----SSSTHSGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITVN
TH_3102|M.thermoresistible__bu IVNIS-----SSSTHSGAPYMAPYVAAKSGVNGLTKTLALEYGPAGITVN
MLBr_01807|M.leprae_Br4923 YIFMG-----SVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
Mb2025|M.bovis_AF2122/97 IINIS-----SIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVN
Rv2002|M.tuberculosis_H37Rv IINIS-----SIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVN
MAB_4680c|M.abscessus_ATCC_199 IVNIS-----SAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVN
Mflv_0943|M.gilvum_PYR-GCK IVNVS-----STVILSPPAPMLHYATAKAALATYTTGLAAEAGPRGVRVN
Mvan_0609|M.vanbaalenii_PYR-1 VVNITSIEAARVIALSNPDPTPQYAASKAGLQMLTQTAARALAADGVRVN
MSMEG_3825|M.smegmatis_MC2_155 IVNVTSIEAARVIALSNPDPTPQYAASKAGLRMLTETSARALAADGIRVN
: : * ::* .: : * . : .*
MMAR_4715|M.marinum_M AVPPGFIDTP----MLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAAC
MUL_0315|M.ulcerans_Agy99 AVPPGFIDTP----MLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAAC
MAV_0942|M.avium_104 AVPPGFIDTP----MLRAAEKNGFLGDIEETIARTPVRRMGTPQDIAAAC
TH_3102|M.thermoresistible__bu AVPPGFIDTP----MLRAAAAKGYLGDIDKTIEATPVRRMGKPEDIAAAC
MLBr_01807|M.leprae_Br4923 VVAPGFIDTE----MTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAV
Mb2025|M.bovis_AF2122/97 SIHPGLVKTP----MTDWV---------PEDIFQTALGRAAEPVEVSNLV
Rv2002|M.tuberculosis_H37Rv SIHPGLVKTP----MTDWV---------PEDIFQTALGRAAEPVEVSNLV
MAB_4680c|M.abscessus_ATCC_199 SVHPGVIYTP----MTAKEGFR----EGEGNMPIAAMGRVGNADEVAGAV
Mflv_0943|M.gilvum_PYR-GCK TVTPGNVTSPGADAIRQAIVDSGGADAPAAGGTPIPLGRKGEASDIAEAI
Mvan_0609|M.vanbaalenii_PYR-1 SVSPGFVATP------MAAAHGDTTDLPPALAPRVPAGRFAEPADIANAV
MSMEG_3825|M.smegmatis_MC2_155 SVAPGFVATP------MAAAHGNTATLPPSLAPRVPAGRFARPAEIAWAT
: ** : : . * . :::
MMAR_4715|M.marinum_M AFLVSEEAGYITGQILGVNGGRNT--------------------
MUL_0315|M.ulcerans_Agy99 AFLVSEEAGYITGQILGVNGGRNT--------------------
MAV_0942|M.avium_104 AFLVSEEAGYITGQILGVNGGRNT--------------------
TH_3102|M.thermoresistible__bu AFLISEEAGYITGQILGVNGGRNT--------------------
MLBr_01807|M.leprae_Br4923 SFLASEDAGYISGAVIPVDGGLGMGH------------------
Mb2025|M.bovis_AF2122/97 VYLASDESSYSTGAEFVVDGGTVAGLAHNDFGAVEVSSQPEWVT
Rv2002|M.tuberculosis_H37Rv VYLASDESSYSTGAEFVVDGGTVAGLAHNDFGAVEVSSQPEWVT
MAB_4680c|M.abscessus_ATCC_199 AYLLSDAASYVTGAELAVDGGWTAGPT-----LTTITGQ-----
Mflv_0943|M.gilvum_PYR-GCK AFLVSDRAAWITATNLVIDGGQIQAG------------------
Mvan_0609|M.vanbaalenii_PYR-1 AFLLSDQAGYITGSDLRVDGGFQLT-------------------
MSMEG_3825|M.smegmatis_MC2_155 AFLLCDQATYITGSELRADGGFQLT-------------------
:* .: : : :. : :**