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MTVAAQTGQAPTKSLAYTFTGGDAVVTGAASGIGAATAAMLMSAGIRTIRLDIRTPEPDPGFGADLQVCC AADVRDPDLLTTLRGQGAPVDTVSYVVNCAGVIDDTGFAGVSREHWLRCLEINLMGAYNVLDAFTPVLRQ NPPAAIVNVTSIEAARVIALSNPDPTPQYAASKAGLRMLTETSARALAADGIRVNSVAPGFVATPMAAAH GNTATLPPSLAPRVPAGRFARPAEIAWATAFLLCDQATYITGSELRADGGFQLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3825 | - | - | 100% (264) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_6538 | - | 2e-26 | 32.79% (244) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_2566 | - | 2e-26 | 39.02% (246) | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 1e-21 | 29.20% (250) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4104 | - | 3e-26 | 38.15% (249) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1928c | - | 1e-21 | 29.20% (250) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-19 | 29.07% (258) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 3e-27 | 34.94% (249) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4715 | - | 3e-30 | 35.83% (240) | 3-oxoacyl- |
| M. avium 104 | MAV_0942 | - | 5e-26 | 32.92% (240) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. thermoresistible (build 8) | TH_3102 | - | 3e-26 | 33.61% (241) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 1e-28 | 34.58% (240) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_0609 | - | 1e-102 | 71.65% (254) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104 ----------MK----------TAVVTGGGSGIGLAVVERLRADGLNVAS
TH_3102|M.thermoresistible__bu ----------LK----------NAVVTGGGSGIGQAVAARLRADGYHVAT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_4680c|M.abscessus_ATCC_199 ----------MNG-NSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MSMEG_3825|M.smegmatis_MC2_155 MTVAAQTGQAPTKSLAYTFTGGDAVVTGAASGIGAATAAMLMSAGIRTIR
Mvan_0609|M.vanbaalenii_PYR-1 -----MSAAVPPPGLPLTFSGGDALVTGAASGIGAAIARTLVSAGVRTIG
Mflv_4104|M.gilvum_PYR-GCK -----------------MAADRIALVTGAARGQGAAIVTRLLQDGFRVAA
::**. * * * .
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGID
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGID
MMAR_4715|M.marinum_M LDLK-------------TPDGELAFSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99 LDLK-------------TPDGGLAFSADVTNRSQVDAALAAIRQRLGPVT
MAV_0942|M.avium_104 IDLR-------------PSDAELAFTADVTDRSQVDAALSAIRAQLGPVT
TH_3102|M.thermoresistible__bu IDLK-------------PGDDEFSHAADVTDRAQVDAAFDAIRTQLGPVT
MLBr_01807|M.leprae_Br4923 THRAS-----------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQ---LAAELGDAARFTHLDVTDAEQWRELIDTTLAGFGTIT
MSMEG_3825|M.smegmatis_MC2_155 LDIRTPEPD-----PGFGADLQVCCAADVRDPDLLTTLR-GQGAPVDTVS
Mvan_0609|M.vanbaalenii_PYR-1 VDLRAPEPD-----PDHPAHLQPGVAVDVRDPDLTARLT-EAGSAPENLA
Mflv_4104|M.gilvum_PYR-GCK CDLLGDDVTR--TVAAHDTDHAVAIELDVTSAEQWTRAVGEVVDRFGGLS
** . :
Mb1963c|M.bovis_AF2122/97 IAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQG
Rv1928c|M.tuberculosis_H37Rv IAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQG
MMAR_4715|M.marinum_M ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MUL_0315|M.ulcerans_Agy99 ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MAV_0942|M.avium_104 VLVNAAGLDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAGWG
TH_3102|M.thermoresistible__bu ILVNAAGLDLFRRFTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAGWG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCG
MSMEG_3825|M.smegmatis_MC2_155 YVVNCAGVIDDTGFAGVSREHWLRCLEINLMGAYNVLDAFTPVLRQNPPA
Mvan_0609|M.vanbaalenii_PYR-1 YLVNCAGVLDNTGFAGVGREMWMRCLDINLVGAYNTIDALSPFLRNASPA
Mflv_4104|M.gilvum_PYR-GCK TLVNNAGVLHRASLADETPDGFEGSWRVNSLGPFLGIQAALPHLKAAEGA
* **: . : : * * : . : .
Mb1963c|M.bovis_AF2122/97 GVIINTASMSG--HIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRV
Rv1928c|M.tuberculosis_H37Rv GVIINTASMSG--HIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRV
MMAR_4715|M.marinum_M RIVNISSSST-----HSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITV
MUL_0315|M.ulcerans_Agy99 RIVNISSSST-----HSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITV
MAV_0942|M.avium_104 RIVNISSSST-----HSGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITV
TH_3102|M.thermoresistible__bu RIVNISSSST-----HSGAPYMAPYVAAKSGVNGLTKTLALEYGPAGITV
MLBr_01807|M.leprae_Br4923 RYIFMGSVVG-----LSGVPGQANYAASKSGLIGMARSLARELGSRSITA
MAB_4680c|M.abscessus_ATCC_199 SIVNISSAAG-----LVGLALTSGYGASKWGVRGLSKVAAIELGRERIRV
MSMEG_3825|M.smegmatis_MC2_155 AIVNVTSIEAARVIALSNPDPTPQYAASKAGLRMLTETSARALAADGIRV
Mvan_0609|M.vanbaalenii_PYR-1 AVVNITSIEAARVIALSNPDPTPQYAASKAGLQMLTQTAARALAADGVRV
Mflv_4104|M.gilvum_PYR-GCK AIVNTCSTGAIRPFPN-----HAAYGSSKWALRGLTQVAAVELAPSGIRV
: : . * ::* .: ::. * . : .
Mb1963c|M.bovis_AF2122/97 NSVSPGYILTELVEPYTEY-----QPLWEPKIPLGRLGRPEELAGLYLYL
Rv1928c|M.tuberculosis_H37Rv NSVSPGYILTELVEPYTEY-----QPLWEPKIPLGRLGRPEELAGLYLYL
MMAR_4715|M.marinum_M NAVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFL
MUL_0315|M.ulcerans_Agy99 NAVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFL
MAV_0942|M.avium_104 NAVPPGFIDTPMLRAAEKNGFLGDIEETIARTPVRRMGTPQDIAAACAFL
TH_3102|M.thermoresistible__bu NAVPPGFIDTPMLRAAAAKGYLGDIDKTIEATPVRRMGKPEDIAAACAFL
MLBr_01807|M.leprae_Br4923 NVVAPGFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFL
MAB_4680c|M.abscessus_ATCC_199 NSVHPGVIYTPMTAKEGFR----EGEGNMPIAAMGRVGNADEVAGAVAYL
MSMEG_3825|M.smegmatis_MC2_155 NSVAPGFVATPMAAAHGNTATL--PPSLAPRVPAGRFARPAEIAWATAFL
Mvan_0609|M.vanbaalenii_PYR-1 NSVSPGFVATPMAAAHGDTTDL--PPALAPRVPAGRFAEPADIANAVAFL
Mflv_4104|M.gilvum_PYR-GCK NAVFPGPVETPMLDANTQTR-------LAANALMGRIGKPMEIADAVAFL
* * ** : * : *.. ::* :*
Mb1963c|M.bovis_AF2122/97 ASEASSYMTGSDIVIDGGYTCP---------
Rv1928c|M.tuberculosis_H37Rv ASEASSYMTGSDIVIDGGYTCP---------
MMAR_4715|M.marinum_M VSEEAGYITGQILGVNGGRNT----------
MUL_0315|M.ulcerans_Agy99 VSEEAGYITGQILGVNGGRNT----------
MAV_0942|M.avium_104 VSEEAGYITGQILGVNGGRNT----------
TH_3102|M.thermoresistible__bu ISEEAGYITGQILGVNGGRNT----------
MLBr_01807|M.leprae_Br4923 ASEDAGYISGAVIPVDGGLGMGH--------
MAB_4680c|M.abscessus_ATCC_199 LSDAASYVTGAELAVDGGWTAGPTLTTITGQ
MSMEG_3825|M.smegmatis_MC2_155 LCDQATYITGSELRADGGFQLT---------
Mvan_0609|M.vanbaalenii_PYR-1 LSDQAGYITGSDLRVDGGFQLT---------
Mflv_4104|M.gilvum_PYR-GCK VSEHATFITGSELIVDGGQSLQIG-------
.: : :::* : :**