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KELAADGIPVAVTCRVLKLSRQPYYRWLADPVTDAELVEAYRTNALVNAHADDPEFGYRYLVEEAREAGE PMAERTAWRICSQNRLWSVFGKKRGKSGKVGPPVHDDLVQRDFTADAPNQLWLSDITEHRTDEGKLYLCA IKDVFSNRIVGYSIDSRMKSRLATRALHSAVARRGDVAGCIVHTDRGSQFRSRRFVHALGHYEMVGSMGR VGAAGDNAAMESFFSLLQKNVLDRRRWATREELRIAIVTWIERTYHRRRRQSGLGRLTPIEFEAIMTTPA SQAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5959 | - | - | 100% (285) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_1094 | - | e-163 | 98.95% (285) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_2522 | - | 2e-32 | 31.65% (297) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 3e-23 | 29.14% (278) | transposase |
| M. gilvum PYR-GCK | Mflv_3195 | - | 1e-156 | 92.63% (285) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv3475 | - | 5e-24 | 29.23% (284) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 1e-138 | 86.45% (273) | transposase |
| M. marinum M | MMAR_3786 | - | 9e-37 | 40.10% (202) | transposase |
| M. avium 104 | MAV_5093 | - | 2e-29 | 32.50% (280) | transposase |
| M. smegmatis MC2 155 | MSMEG_4105 | - | 1e-150 | 90.56% (286) | transposase subunit |
| M. thermoresistible (build 8) | TH_3162 | - | 1e-32 | 36.11% (216) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | MUL_2306 | - | 4e-20 | 62.50% (80) | transposase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3195|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4105|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5959|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M MPRQYSSSVRRQIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALIDAGV
TH_3162|M.thermoresistible__bu --------------------------------------------------
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv -------------------------------------------------A
MAV_5093|M.avium_104 --------------------------------------------------
Mflv_3195|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4105|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5959|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M IEGTPSVEADELAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKRRRAI
TH_3162|M.thermoresistible__bu --------------------------------------------------
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv EALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGPD
MAV_5093|M.avium_104 -----------------------------------MAFIDANRD------
Mflv_3195|M.gilvum_PYR-GCK MKELAADGIPVAVTCRVLKLSRQPYYRWLADPITEAELIEAYRANALFDA
MSMEG_4105|M.smegmatis_MC2_155 MKELAADGIPVAVTCRVLKLARQPYYRWLAAPVTDADLVEAYRANALFDA
Mvan_5959|M.vanbaalenii_PYR-1 MKELAADGIPVAVTCRVLKLSRQPYYRWLADPVTDAELVEAYRTNALVNA
MAB_2088|M.abscessus_ATCC_1997 ------------MTRRVLKLARQPYYRWRANPITDAELVEAYRANALFDA
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M TEGLIARGHSARSACRVTGLARSLLQYHRRRLVPDREVRRLIVADTITEI
TH_3162|M.thermoresistible__bu ------------------------------------------LDAKVAAF
Mb2838c|M.bovis_AF2122/97 -----------------MPIAPSTYYDHINREPSRRELRDGELKEHISRV
Rv3475|M.tuberculosis_H37Rv GLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRV
MAV_5093|M.avium_104 --EFGVEPICTVLRSAGLQVAPSTYYANKTRTPSARAQRDAVMRPVITQL
Mflv_3195|M.gilvum_PYR-GCK HADDP-EFGYRYLVEEARDAGEPMAERTAWRICSQNRLWSVFGK-KRGKN
MSMEG_4105|M.smegmatis_MC2_155 HHEDP-EFGYRYLAEEARDAGEPMAERTAWRICSHNRLWSVFGKRKRGKN
Mvan_5959|M.vanbaalenii_PYR-1 HADDP-EFGYRYLVEEAREAGEPMAERTAWRICSQNRLWSVFGK-KRGKS
MAB_2088|M.abscessus_ATCC_1997 HGEDP-EFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFGK-KRGKN
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M YQRSRGTYGRKRVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHGRRKP
TH_3162|M.thermoresistible__bu HKASDGVYGAPRILADLREDGEKVSRKTVAASLRRQGLAGISPRTFAPVT
Mb2838c|M.bovis_AF2122/97 HAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSG-TTRGKARRT
Rv3475|M.tuberculosis_H37Rv HAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSG-TTRGKARRT
MAV_5093|M.avium_104 WEDNYRVYGARKLWKAARRAGHDIGRDQIARLMREAGIAG-VRRGKRVRT
Mflv_3195|M.gilvum_PYR-GCK GKV--GPPVHDDLVERDFTAEGPNQLWLSDITEHRTGEGKLYLCAIKDVF
MSMEG_4105|M.smegmatis_MC2_155 GKP--GPPVHDDLVERDFTAEAPNQLWLADITEHRTGEGKLYLCAIKDVF
Mvan_5959|M.vanbaalenii_PYR-1 GKV--GPPVHDDLVQRDFTADAPNQLWLSDITEHRTDEGKLYLCAIKDVF
MAB_2088|M.abscessus_ATCC_1997 GKP--GPPVHDDLVQRDFTAETPNMLWLSDITEHYTGDGKLYLCAIKDAF
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M NLI--GVHTPVDLINRRFTATKPNELWCTDITEHPARDGKVYCCAILDCF
TH_3162|M.thermoresistible__bu TIVDLDTPVPKDLVNRRFDVGELDRVWTSDITYLRTGEGWLYLCAVRDGC
Mb2838c|M.bovis_AF2122/97 TIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAY
Rv3475|M.tuberculosis_H37Rv TIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAY
MAV_5093|M.avium_104 TKPGPGAPRHPDLVGRDFTASAPNQLWVTDLTFVPTWAGVAYVCFLTDAF
Mflv_3195|M.gilvum_PYR-GCK SNRIVGYSIDSRMKSQLAIRALHSAVARR-G----DVAGCILHSDRGSQF
MSMEG_4105|M.smegmatis_MC2_155 SNRIVGYSIDSRMKSRLATRALHSAVARR-G----DVAGCILHSDRGSQF
Mvan_5959|M.vanbaalenii_PYR-1 SNRIVGYSIDSRMKSRLATRALHSAVARR-G----DVAGCIVHTDRGSQF
MAB_2088|M.abscessus_ATCC_1997 SNRIVGYSIDSRMKSRLATAALRNAVGRR-G----VVAGCVVHTDRGSQF
MUL_2306|M.ulcerans_Agy99 ---MVG--------------------------------------------
MMAR_3786|M.marinum_M SRMIVARTFSTTADTALVNNAVNMAVDHR-N----RSGPTILHADHGTQF
TH_3162|M.thermoresistible__bu SRRVIGWAIDDHMHTDLVESAVAMAVAMRGQ----LAEQVVLHADRGCQF
Mb2838c|M.bovis_AF2122/97 ARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQY
Rv3475|M.tuberculosis_H37Rv ARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQY
MAV_5093|M.avium_104 SRMIIGWRVASHMRTTVVLDTIEMARWSRGK----MLAGLRCHSDAGSQF
::.
Mflv_3195|M.gilvum_PYR-GCK RSRKFVHALNHHEMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRR
MSMEG_4105|M.smegmatis_MC2_155 RSRRFVHALHHHDMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRR
Mvan_5959|M.vanbaalenii_PYR-1 RSRRFVHALGHYEMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRR
MAB_2088|M.abscessus_ATCC_1997 RSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRR
MUL_2306|M.ulcerans_Agy99 -------------TVGAMGRVQAAGDNAAMASFFSLLRKNVLG----RRR
MMAR_3786|M.marinum_M TSWSFGENMRRWGLLGSFGTVGDCFDNAAMESFWARLQVELLN----TRK
TH_3162|M.thermoresistible__bu TSAQLARFSRGHNLARSVGRTGVCWDNAQHESFWGTMKVEFYD----RHL
Mb2838c|M.bovis_AF2122/97 TSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK-PGKP--
Rv3475|M.tuberculosis_H37Rv TSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK-PGKP--
MAV_5093|M.avium_104 TSIRYSERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELIYGPARPGP
:.* . . *** :. . : :.
Mflv_3195|M.gilvum_PYR-GCK WDTREQLRIAIVTWIERTYHRRRRQSGLGRLTPIEFEAIMTTPASQAA--
MSMEG_4105|M.smegmatis_MC2_155 WRTREELRIAIVIWIERTYHRRRRQAGLDRLTPIEFEAIMTTPASQAA--
Mvan_5959|M.vanbaalenii_PYR-1 WATREELRIAIVTWIERTYHRRRRQSGLGRLTPIEFEAIMTTPASQAA--
MAB_2088|M.abscessus_ATCC_1997 WATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA--
MUL_2306|M.ulcerans_Agy99 WETREHLRIAIATWTETHLRPPPSASRSWPVAPVRFEAIMISRAIQAA--
MMAR_3786|M.marinum_M WATTIELAAAMADYIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA
TH_3162|M.thermoresistible__bu WPTKAAAKLAVGDWIERVYNRRRRPSATPAAAATQRSA------------
Mb2838c|M.bovis_AF2122/97 WRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQR--QRPA
Rv3475|M.tuberculosis_H37Rv WRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQR--QRPA
MAV_5093|M.avium_104 WKTVEDVELATLSWVH-WHNTSRLHGYLNDVPPAEFEAAFYATKRTDHPL
* : * : . . .. . .:
Mflv_3195|M.gilvum_PYR-GCK ----
MSMEG_4105|M.smegmatis_MC2_155 ----
Mvan_5959|M.vanbaalenii_PYR-1 ----
MAB_2088|M.abscessus_ATCC_1997 ----
MUL_2306|M.ulcerans_Agy99 ----
MMAR_3786|M.marinum_M ----
TH_3162|M.thermoresistible__bu ----
Mb2838c|M.bovis_AF2122/97 AG--
Rv3475|M.tuberculosis_H37Rv AG--
MAV_5093|M.avium_104 VEIQ