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DKFLHYLTLPWLIDGMLFTLQLTLYGFTGGLFLGVLLAALQLTRSRALTAIGRTYVVIYRGTPLILQLVF VFTALPHIGITLPPVAAGSVALAMNEAVFISEILRSGIKGVDPGQSLAGRALGLEPRKLMRRVIAPQAFR SMVPALGNEFISTMKNSALASVIAVPELTLRTQQLASSTFDYFSIYFATAVMYLALTAVLSIIQLLLEDA LNLDRANRSLLSRLDFRRRTTTPTPVVTPVVPAGPQVERQEIGDTVLDIRDLHKAYGANQVLNGITMSAR QGEVIALLGPSGSGKSTLLRTINHLESVDTGTIRIAGQTLGYDESGMPLPEGRIAKARIDAGVGMVFQHF NLFNHMTVRENIAAPLRWIQRLGKEEAAERADALLSQVGLADKADTLPHRLSGGQQQRVGIARALAARPR ILLLDEPTSALDPELVAEVLGVIRGLAHHHGLTMIIATHQLRFALEVADRAVFMAGGVVVEEGSADQVIN RPQDPATARFVNAMQLAAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0292 | - | - | 100% (510) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_2834 | - | 9e-63 | 53.31% (242) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2428 | - | 1e-56 | 45.12% (246) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-40 | 40.24% (251) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3581 | - | 3e-63 | 53.72% (242) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-40 | 40.24% (251) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-35 | 34.92% (252) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4237c | - | 2e-63 | 51.98% (252) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 7e-47 | 41.63% (257) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 2e-49 | 42.68% (246) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3237 | - | 3e-65 | 52.76% (254) | ATP-binding protein |
| M. thermoresistible (build 8) | TH_1784 | - | 4e-55 | 45.12% (246) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-40 | 38.91% (257) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0292|M.vanbaalenii_PYR-1 MDKFLHYLTLPWLIDGMLFTLQLTLYGFTGGLFLGVLLAALQLTRSRALT
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0292|M.vanbaalenii_PYR-1 AIGRTYVVIYRGTPLILQLVFVFTALPHIGITLPPVAAGSVALAMNEAVF
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0292|M.vanbaalenii_PYR-1 ISEILRSGIKGVDPGQSLAGRALGLEPRKLMRRVIAPQAFRSMVPALGNE
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0292|M.vanbaalenii_PYR-1 FISTMKNSALASVIAVPELTLRTQQLASSTFDYFSIYFATAVMYLALTAV
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 ----------------------------------------MT------YA
Rv2397c|M.tuberculosis_H37Rv ----------------------------------------MT------YA
MUL_3658|M.ulcerans_Agy99 ----------------------------------------MTGPGTGGHA
Mflv_3581|M.gilvum_PYR-GCK ------------------------------------MTTSEN-SAHPMVK
MSMEG_3237|M.smegmatis_MC2_155 ------------------------------------MTTAEATSGDYMVR
Mvan_0292|M.vanbaalenii_PYR-1 LSIIQLLLEDALNLDRANRSLLSRLDFRRRTTTPTPVVTPVVPAGPQVER
MAB_4237c|M.abscessus_ATCC_199 -----------------------------------------------MST
MMAR_0060|M.marinum_M --------------------------------------MTRQDAGRQPVC
MAV_0058|M.avium_104 --------------------------------------MS-NPASRASVS
TH_1784|M.thermoresistible__bu ------------------------------MDSAGADVAVADPAAEAVPM
MLBr_01089|M.leprae_Br4923 -----------------------------------------------MAE
Mb2419c|M.bovis_AF2122/97 IVVAD-------ATKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTL
Rv2397c|M.tuberculosis_H37Rv IVVAD-------ATKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTL
MUL_3658|M.ulcerans_Agy99 IVVRD-------AFKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTL
Mflv_3581|M.gilvum_PYR-GCK AEL---------VCKDFG-ALKVLKGITLEVQKGQVLVLVGPSGSGKSTL
MSMEG_3237|M.smegmatis_MC2_155 AES---------VCKNFG-ALKVLRGVTLNVSKGQVLVLVGPSGSGKSTF
Mvan_0292|M.vanbaalenii_PYR-1 QEIGDTVLDIRDLHKAYG-ANQVLNGITMSARQGEVIALLGPSGSGKSTL
MAB_4237c|M.abscessus_ATCC_199 IEVRG-------VRKSYG-QVTALRDVNLTVHQGEVTVIIGPSGSGKSTL
MMAR_0060|M.marinum_M LAARS-------IHQTLG-GSVVLRGVDLEVPAGTTAAVIGPSGSGKSTL
MAV_0058|M.avium_104 LACKD-------IHQTLN-GNAVLRGVDLDTPAGSTVAVIGPSGSGKSTL
TH_1784|M.thermoresistible__bu ISMRG-------VNKYFG-SLHVLRDINLDVARGQVVVVLGPSGSGKSTL
MLBr_01089|M.leprae_Br4923 IVLEH-------VNKNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTT
: .: : : . * ::****.**:*
Mb2419c|M.bovis_AF2122/97 LRTIAGLDQPDTGTITINGRDVTRVPP--------------QRRGIGFVF
Rv2397c|M.tuberculosis_H37Rv LRTIAGLDQPDTGTITINGRDVTRVPP--------------QRRGIGFVF
MUL_3658|M.ulcerans_Agy99 LRTIAGLDQPDSGNITINGRDVTRVPP--------------QRRGIGFVF
Mflv_3581|M.gilvum_PYR-GCK LRCINHLETVSAGRLYVDGTLVGYHERGGKLYEMKPRDVARQRRDVGMVF
MSMEG_3237|M.smegmatis_MC2_155 LRCINHLETVSAGRLYVDGQLVGYRERGGKLHEMKPSDVAKQRRDVGMVF
Mvan_0292|M.vanbaalenii_PYR-1 LRTINHLESVDTGTIRIAGQTLGYDESGMPLPEGR-IAKARIDAGVGMVF
MAB_4237c|M.abscessus_ATCC_199 LRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPERAILRQRSQVGFVF
MMAR_0060|M.marinum_M LRTLNRLHEPDSGDILLDGRSVLRD------------NPNDLRQRIGMVF
MAV_0058|M.avium_104 LRTLNRLYEPDRGDILLDGRSVLHD------------DPDQLRQRIGMVF
TH_1784|M.thermoresistible__bu CRTLNRLEPIDSGAISIDGVALPAEGR----------ELARLRADVGMVF
MLBr_01089|M.leprae_Br4923 LNMIAGLEDISSGELRIDGDRVNEKAP--------------KDRDIAMVF
. : * . * : : * : :.:**
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVVGLSGFQSRY
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVVGLSGFQSRY
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNLLEVVGLSGFHGRY
Mflv_3581|M.gilvum_PYR-GCK QHFNLFPHRTALGNVVEAPIQVKGVKKDEAVTRGRELLAQVGLADKADAY
MSMEG_3237|M.smegmatis_MC2_155 QHFNLFPHRTALANIIEAPIKVKGVKKKEAIDRARDLLNQVGLADKAEAY
Mvan_0292|M.vanbaalenii_PYR-1 QHFNLFNHMTVRENIAAPLRWIQRLGKEEAAERADALLSQVGLADKADTL
MAB_4237c|M.abscessus_ATCC_199 QNFNLFPHLTVLENVIEAPLAARRAPRAELEAEATRLLERVGVADKAAQY
MMAR_0060|M.marinum_M QHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRVGLKHKANAR
MAV_0058|M.avium_104 QHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRVGLKHKAGAR
TH_1784|M.thermoresistible__bu QQFNLFAHKTIVDNVALGPMKVRKTPREQARAEAMALLERVGVADQADKY
MLBr_01089|M.leprae_Br4923 QSYALYPHMTVRQNIAFP-LMLAKVKKAEIAQKVSETAQILDLTDLLDRK
* : : * . *: :.:
Mb2419c|M.bovis_AF2122/97 PNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLH
Rv2397c|M.tuberculosis_H37Rv PNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLH
MUL_3658|M.ulcerans_Agy99 PDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLH
Mflv_3581|M.gilvum_PYR-GCK PAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGEVLAVMKKLA
MSMEG_3237|M.smegmatis_MC2_155 PAQLSGGQQQRVAIARALAMNPKLMLFDEPTSALDPELVGDVLGVMKKLA
Mvan_0292|M.vanbaalenii_PYR-1 PHRLSGGQQQRVGIARALAARPRILLLDEPTSALDPELVAEVLGVIRGLA
MAB_4237c|M.abscessus_ATCC_199 PRRLSGGQQQRVAIARALALRPKVILFDEPTSALDPELVTEVLDVIAQLA
MMAR_0060|M.marinum_M PDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGILALIADLG
MAV_0058|M.avium_104 PATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPEMVKGILQLIADLG
TH_1784|M.thermoresistible__bu PAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEVLAVMSALA
MLBr_01089|M.leprae_Br4923 PSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQ
* *****:**:.:.*::. *. :::**. . **.:: : *
Mb2419c|M.bovis_AF2122/97 DEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFV
Rv2397c|M.tuberculosis_H37Rv DEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFV
MUL_3658|M.ulcerans_Agy99 DEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFV
Mflv_3581|M.gilvum_PYR-GCK A-QGMTMVVVTHEMGFAREVADELVFMDEGVVVERGNPREVMSNPQHERT
MSMEG_3237|M.smegmatis_MC2_155 S-EGMTMVVVTHEMGFAREVADKLVFMDGGVIVESGDPREVMANPKHERT
Mvan_0292|M.vanbaalenii_PYR-1 HHHGLTMIIATHQLRFALEVADRAVFMAGGVVVEEGSADQVINRPQDPAT
MAB_4237c|M.abscessus_ATCC_199 R-DGATLVIVTHEIGLAREIADTVVFMDRGAIVEQGPPKEVLDSPSHPRT
MMAR_0060|M.marinum_M A-DGMTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGPPEQLFEAARTERL
MAV_0058|M.avium_104 A-EGMTMVVVTHEMGFARSASDAVIFMDHGKVVESGPPEQIFEAAETERL
TH_1784|M.thermoresistible__bu A-DGMTMLVVTHEMGFARRASDRVVFMSDGAIVEDAEPARFFEDPQTDRA
MLBr_01089|M.leprae_Br4923 RRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFV
* : .**: * .* .: * : : . . . .
Mb2419c|M.bovis_AF2122/97 MSFLG---------------------------AVSTLNGSLVRPHDIRVG
Rv2397c|M.tuberculosis_H37Rv MSFLG---------------------------AVSTLNGSLVRPHDIRVG
MUL_3658|M.ulcerans_Agy99 MSFLG---------------------------AVSALNGALVRPHDIRVG
Mflv_3581|M.gilvum_PYR-GCK KAFLS---------------------------KVM---------------
MSMEG_3237|M.smegmatis_MC2_155 KAFLS---------------------------KVM---------------
Mvan_0292|M.vanbaalenii_PYR-1 ARFVN---------------------------AMQLAAG-----------
MAB_4237c|M.abscessus_ATCC_199 ASFLS---------------------------KVLS--------------
MMAR_0060|M.marinum_M QRFLA---------------------------QVL---------------
MAV_0058|M.avium_104 QRFLS---------------------------QVL---------------
TH_1784|M.thermoresistible__bu RDFLG---------------------------KILHH-------------
MLBr_01089|M.leprae_Br4923 AGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVG
*: :
Mb2419c|M.bovis_AF2122/97 RTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQ
Rv2397c|M.tuberculosis_H37Rv RTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQ
MUL_3658|M.ulcerans_Agy99 RTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQ
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0292|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 VRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYS
Mb2419c|M.bovis_AF2122/97 ITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST---
Rv2397c|M.tuberculosis_H37Rv ITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST---
MUL_3658|M.ulcerans_Agy99 ITRGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGV
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0292|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 AQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSG
Mb2419c|M.bovis_AF2122/97 -----------
Rv2397c|M.tuberculosis_H37Rv -----------
MUL_3658|M.ulcerans_Agy99 GGQ--------
Mflv_3581|M.gilvum_PYR-GCK -----------
MSMEG_3237|M.smegmatis_MC2_155 -----------
Mvan_0292|M.vanbaalenii_PYR-1 -----------
MAB_4237c|M.abscessus_ATCC_199 -----------
MMAR_0060|M.marinum_M -----------
MAV_0058|M.avium_104 -----------
TH_1784|M.thermoresistible__bu -----------
MLBr_01089|M.leprae_Br4923 VNLTVSAPTDA