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MTRIVIAEDSAILREGLAQLIAERGHDVVAAVGNADDMLGAVREFAPDVVVVDIRMPPTFTDEGLVAAVS LRRSHPEVGVLVFSQWVETRYATELLAGNAEGVGYLLKDRVADIAEFDAALQRVAARGTALDPEVVRQLM GSRGTSALDRLSPREREVLALMAEGHSNLSLARQLSITERSVEKHVSAIFTKLDLAPSQAHHRRVLAVLT YLDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0263 | - | - | 100% (214) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4386 | - | 6e-58 | 55.45% (211) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2073 | - | 3e-48 | 48.36% (213) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 3e-14 | 26.37% (201) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_2280 | - | 6e-59 | 54.46% (213) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 3e-14 | 26.37% (201) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_01286 | - | 2e-09 | 30.15% (136) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_4498c | - | 9e-52 | 50.24% (211) | two-component LuxR family response regulator |
| M. marinum M | MMAR_3959 | - | 1e-15 | 32.35% (204) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_5280 | - | 6e-18 | 32.02% (203) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_4969 | - | 2e-61 | 55.40% (213) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_1532 | - | 2e-59 | 55.40% (213) | two-component system response regulator |
| M. ulcerans Agy99 | MUL_3814 | - | 7e-16 | 32.84% (204) | two component transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4969|M.smegmatis_MC2_155 -------------MRIVIAEDSALLRAGIERILADA-GHDVIAGVPDATN
TH_1532|M.thermoresistible__bu -------------MRIVIAEDSALLRAGIERILTDA-GHEVVAGVPDATD
Mflv_2280|M.gilvum_PYR-GCK -------------MRIVIAEDSALLRAGIERILTDA-GHQVVAGVPDATD
Mvan_0263|M.vanbaalenii_PYR-1 ------------MTRIVIAEDSAILREGLAQLIAER-GHDVVAAVGNADD
MAB_4498c|M.abscessus_ATCC_199 ----------MSAIRVLVADDDTLLREGVASVLEKA-GFEVVGRAGDATA
Mb3157c|M.bovis_AF2122/97 ------------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAE
Rv3133c|M.tuberculosis_H37Rv ------------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAE
MMAR_3959|M.marinum_M -------MSEHESPTVMVVDDHPIWRDAVARDLSDD-GFAVVATADGVAT
MUL_3814|M.ulcerans_Agy99 -------MSEHESPTVMVVDDHPIWRDAVARDLSDD-GFAVVATADGVAT
MAV_5280|M.avium_104 ------MTDPAPEITVLLVDDQDLVRSGLRRILRRKDGFVIVAECADGDE
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDE-GYDIVGEAADGQE
:.:.:* : * : : ::. .
MSMEG_4969|M.smegmatis_MC2_155 LLNLVNEHRPDLAILDVRMPPTFTDEGIRAAALLRKQNPESPVLVLSHYV
TH_1532|M.thermoresistible__bu LLRLVNELRPDLAIVDVRMPPTFTDEGIRAAALLRSQNPESPVLVLSHYV
Mflv_2280|M.gilvum_PYR-GCK LLRLVNDERPDLAILDVRMPPTFTDEGIRAAALLRSQNPESPVLVLSHYV
Mvan_0263|M.vanbaalenii_PYR-1 MLGAVREFAPDVVVVDIRMPPTFTDEGLVAAVSLRRSHPEVGVLVFSQWV
MAB_4498c|M.abscessus_ATCC_199 LLELVRTESPNLVVVDIRMPPTHTTEGLEAAQKIRGEHPGIGVLVLSAHV
Mb3157c|M.bovis_AF2122/97 AMARVPAARPDVAVLDVRLP---DGNGIELCRDLLSRMPDLRCLILTSYT
Rv3133c|M.tuberculosis_H37Rv AMARVPAARPDVAVLDVRLP---DGNGIELCRDLLSRMPDLRCLILTSYT
MMAR_3959|M.marinum_M AQRRAAIVKPDVVVMDMRLA---DGDGVQATTEVLKVSPATRVLVLSASD
MUL_3814|M.ulcerans_Agy99 AQRRAAIVKPDVVVMDMRLA---DGDGVQATTEVLKVSPATRVLVLSTSD
MAV_5280|M.avium_104 VPAAVAAHRPDVVVMDLRMR---RVDGIEATRRLGGRPP---VLALTTFN
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMP---RRDGIDAASEIASKRIAP-IVVLTAFS
. *::.::*::: :*: : : ::
MSMEG_4969|M.smegmatis_MC2_155 EERYASDLIASDTKGFGYLLKDRVADVPAFLDAVEVVGRGGTVLDPEVVS
TH_1532|M.thermoresistible__bu EERYAADLIASDTKGFGYLLKDRVADVPAFLDAVEVVGGGGTVLDPEVVS
Mflv_2280|M.gilvum_PYR-GCK EERYAADLIASDTRGFGYLLKDRVADVPAFLDAVEVVGAGGTVLDPEVVS
Mvan_0263|M.vanbaalenii_PYR-1 ETRYATELLAGNAEGVGYLLKDRVADIAEFDAALQRVAARGTALDPEVVR
MAB_4498c|M.abscessus_ATCC_199 EVEYAAELITSG-DGVGYLLKSRIGDVGEFADACTRVAGGGSIVDPELVR
Mb3157c|M.bovis_AF2122/97 SDEAMLDAILAG--ASGYVVKD--IKGMELARAVKDVGAGRSLLDNRAAA
Rv3133c|M.tuberculosis_H37Rv SDEAMLDAILAG--ASGYVVKD--IKGMELARAVKDVGAGRSLLDNRAAA
MMAR_3959|M.marinum_M EREDVLEAVKAG--ATGYLVKS--ASKAELADAVRATAAGRAVFTPSLAG
MUL_3814|M.ulcerans_Agy99 EREDVLEAVKTG--ATGYLVKS--ASKAELADAVRATAAGRAVFTPSLAG
MAV_5280|M.avium_104 EDELLSGALRAG--AAGFVLKD--SSAEELIRAVRAVARGEGYLDPAVTS
MLBr_01286|M.leprae_Br4923 QRDLVERARDAG--AMAYLVKP--FTISDLIPAIALAMSR--------FS
. . . .:::* : * .
MSMEG_4969|M.smegmatis_MC2_155 QILVRSHRRSA-------LDQLTPREHDVLQLMAEGKTNSAIASALHISI
TH_1532|M.thermoresistible__bu QILVRSHRRSA-------LDELTAREHDVLRLMAEGKTNSAIAGALHISI
Mflv_2280|M.gilvum_PYR-GCK QILARSHRRNV-------LDALTPRENEVLQLMAEGKTNSAIASGLHMSV
Mvan_0263|M.vanbaalenii_PYR-1 QLMG-SRGTSA-------LDRLSPREREVLALMAEGHSNLSLARQLSITE
MAB_4498c|M.abscessus_ATCC_199 ELLSARRKDDP-------LSALSQRELEVLELMAQGLSNSGIAGRLWITE
Mb3157c|M.bovis_AF2122/97 ALMAKLRGAAEKQDPLSG---LTDQERTLLGLLSEGLTNKQIADRMFLAE
Rv3133c|M.tuberculosis_H37Rv ALMAKLRGAAEKQDPLSG---LTDQERTLLGLLSEGLTNKQIADRMFLAE
MMAR_3959|M.marinum_M LVLGEYRRIAQTADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSH
MUL_3814|M.ulcerans_Agy99 LVLGEYRRIAQTADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSH
MAV_5280|M.avium_104 RVLTTYRKAAP-GPHGAAIAELTTRERDVLTLIGKGLSNSEIADELCISG
MLBr_01286|M.leprae_Br4923 ELTALEREVAT----------LADR-LETRKLVERAKGLLQVKQGMTEPE
: : *: : : .. : : .
MSMEG_4969|M.smegmatis_MC2_155 GSAEKHIASIFTKLDLAPDESENRRVLAVLRFLET----
TH_1532|M.thermoresistible__bu GSAEKHIASIFTKLGLEPDESENRRVLAVLRYLES----
Mflv_2280|M.gilvum_PYR-GCK GSAEKHIASIFTKLGLAPDDTENRRVLAVLRYLES----
Mvan_0263|M.vanbaalenii_PYR-1 RSVEKHVSAIFTKLDLAPSQAHHRRVLAVLTYLDS----
MAB_4498c|M.abscessus_ATCC_199 STVEKHVHSVMRRLDLGHADEYHRRVLAVLAFLTHR---
Mb3157c|M.bovis_AF2122/97 KTVKNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Rv3133c|M.tuberculosis_H37Rv KTVKNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
MMAR_3959|M.marinum_M RTVENHVQATFRKLQVANRVELTRYAIEHGLDK------
MUL_3814|M.ulcerans_Agy99 RTVENHVQATFRKLQLANRVELTRYAIEHGLDK------
MAV_5280|M.avium_104 VTVKSHIGRIFGKLDLRDRAAAIVYAYDNGIVAPR----
MLBr_01286|M.leprae_Br4923 AFKWIQRAAMDRRTTMKRVAEVVLETLDTPKDT------
: : .