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VTDDPSPEHAALPDPSALRASAHPDPSALRASAHPDPSALRASAHRRDRLRELLDAVTDSANADVGDMAR SSYASEFHFSREVRRLTGESPAALRRRVMLERAAWRLQRGEAVSAVAADEGWSSAEVFSRAFRRMYGLPP SQASDVHFRLPAPNGLHFHPPQSLWLDSDPGDRTPPGMHTPDIAQLMIDHDIADTSHLLGQAALLSPQQW VAEVAPGQTVLEWDGPEPSVGAVLGAIVWTKQVWLATIAGDDFPSRACTQPEFVDAATLAAHHDDVGNRW RAMVSEYAVAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRGLARTMLAGHGVTTRLGDPLDWMRG N
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0236 | - | - | 100% (351) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3612 | - | 9e-08 | 34.23% (111) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0972 | - | 7e-07 | 33.00% (100) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 1e-05 | 32.91% (79) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0432 | - | 1e-147 | 83.28% (305) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv1931c | - | 1e-05 | 32.91% (79) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0767c | - | 3e-06 | 30.09% (113) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 5e-05 | 30.00% (100) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0307 | - | 1e-125 | 72.28% (303) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_1906 | - | 1e-122 | 69.51% (305) | transcriptional regulator, AraC family protein |
| M. ulcerans Agy99 | MUL_2902 | - | 3e-05 | 30.00% (100) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0236|M.vanbaalenii_PYR-1 MTDDPSPEHAALPDPSALRASAHPDPSALRASAHPDPSALRASAHRRDRL
Mflv_0432|M.gilvum_PYR-GCK -MNDP---------------------------------------ARRDRL
MSMEG_0307|M.smegmatis_MC2_155 --MEP---------------------------------------NGRDRL
TH_1906|M.thermoresistible__bu -VSEQ-------------------------------------ALTGRDRL
Mb1966c|M.bovis_AF2122/97 -----------------------------------------------MVI
Rv1931c|M.tuberculosis_H37Rv -----------------------------------------------MVI
MMAR_2855|M.marinum_M -------------------------------------------MARKVVI
MUL_2902|M.ulcerans_Agy99 -------------------------------------------MARKVVT
MAB_0767c|M.abscessus_ATCC_199 ------------------------------------------MIHNPDYF
Mvan_0236|M.vanbaalenii_PYR-1 RELLDAVTDSANADVGDMARSSYASEFHFSREVRRLTGES----------
Mflv_0432|M.gilvum_PYR-GCK RELLDAVTDAGNSGVGDMARSTYASEFHFSREVRRLTGEA----------
MSMEG_0307|M.smegmatis_MC2_155 RELLDAVVDSENDGVGDMARNSYASEFHFSREVRRLTGEP----------
TH_1906|M.thermoresistible__bu RELLDAVVDAANTDVESMARSSHFSEFHFSREVRRLAGEP----------
Mb1966c|M.bovis_AF2122/97 VGFPG---------------------------------------------
Rv1931c|M.tuberculosis_H37Rv VGFPG---------------------------------------------
MMAR_2855|M.marinum_M VGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVATGIGLEFM
MUL_2902|M.ulcerans_Agy99 VGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVATGIGLEFM
MAB_0767c|M.abscessus_ATCC_199 ADQPKSLSWPTGSPSIDAFSGILSAIGLRGESALRCS-------------
Mvan_0236|M.vanbaalenii_PYR-1 ------PAALRRRVMLERAAWRLQRGEAVSAVAADEGWSSAEVFSRAFRR
Mflv_0432|M.gilvum_PYR-GCK ------PAALRRRVMLERAAWRLQHGEPVSAVAADEGWSSPEVFSRAFRR
MSMEG_0307|M.smegmatis_MC2_155 ------PAALRRRIMLERAAWRLRQGAGVAEVAAAEGWSSPEVFSRAFRR
TH_1906|M.thermoresistible__bu ------PAAMRRRVMLERAAWRLQRGESVSAVAAAEGWSSAEVFSRAFRR
Mb1966c|M.bovis_AF2122/97 --------DPVDTVILPGGAG----VDAARSEPALIDWVKAVSGTARRVV
Rv1931c|M.tuberculosis_H37Rv --------DPVDTVILPGGAG----VDAARSEPALIDWVKAVSGTARRVV
MMAR_2855|M.marinum_M TTRLPDPSAPVDTVVLPGGGG----VDAARDNVALMDWVKAAAGTARRVV
MUL_2902|M.ulcerans_Agy99 TTRLPDPSAPVDTVVLPGGGG----VDAARDNVALMDWVKAAAGTARRVV
MAB_0767c|M.abscessus_ATCC_199 -------AELPFDVSVPANERVLHIAETAGLRVYVDGNPVCVLAAGDMVL
: : . . :
Mvan_0236|M.vanbaalenii_PYR-1 MYGLPPSQASDVHFRLPAPNGLHFHPPQSLWLDSDPGDRTPPGMHTPDIA
Mflv_0432|M.gilvum_PYR-GCK TYGVPPSQAVDVHFRLPSPNGLHFHPPQSLWLDSDRSD--DPG--VPDIA
MSMEG_0307|M.smegmatis_MC2_155 AFGVPPSRATDVGFRLPAPNGVHFHPPRSLWCDGRAGG---GG---PDIA
TH_1906|M.thermoresistible__bu AFGVPPSRVAEVHYLLPAPNGVHFHPPHALWVDGPGSRGAPAG-SVPEIS
Mb1966c|M.bovis_AF2122/97 TVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFRPR-ISGRSGRCRPDL
Rv1931c|M.tuberculosis_H37Rv TVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFRPR-ISGRSGRCRPDL
MMAR_2855|M.marinum_M TVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRSSP
MUL_2902|M.ulcerans_Agy99 TVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRSSP
MAB_0767c|M.abscessus_ATCC_199 MARGTAHRLSGAQPHGEPAGTLHWVSG---RFTAERKAADPLLSVLPPAI
. . .
Mvan_0236|M.vanbaalenii_PYR-1 QLMIDHDIADTSHLLGQAALLSPQQWVAEVAPGQTVLEWDGPEPSVGAVL
Mflv_0432|M.gilvum_PYR-GCK ALMIAHDIDDTAYLLTRAAELTRAQWTAEVAPGQTVLEWDGPEPSVGAVL
MSMEG_0307|M.smegmatis_MC2_155 QFMLVHDIADTAYLIEQAYALTENQWRQEVSPGQTVLDWDGPEPSVAAVL
TH_1906|M.thermoresistible__bu AVLVDHDVADTDYLLECACTLTDRQWAEEISPGQQVLAWDGPEPSVGAVL
Mb1966c|M.bovis_AF2122/97 HAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARP-VSAPTRW
Rv1931c|M.tuberculosis_H37Rv HAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARP-VSAPTRW
MMAR_2855|M.marinum_M KVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRP-GGQ-TQF
MUL_2902|M.ulcerans_Agy99 KVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRP-CGQ-TQF
MAB_0767c|M.abscessus_ATCC_199 IIQAARPGHEWLPLSLQLILAEILTPSPGSWVMISRILDLLFIHAVREWS
.
Mvan_0236|M.vanbaalenii_PYR-1 GAIVWTKQVWLATIAGDDFPSRACTQPEFVDAATLAAHHDDVGNRWRAMV
Mflv_0432|M.gilvum_PYR-GCK GALVWNKEVWLATIAGEDFPSRAATQPDLVDARTLAAHHDDIAKRWRAMI
MSMEG_0307|M.smegmatis_MC2_155 AAIVWTKEVWLATIEGRDFPSRDTTCN--ASPRELAVHHDTVGNRWTTVI
TH_1906|M.thermoresistible__bu GAIVWTKQVWLATIEGADFPTRQHLPP-----SALRDHHRDVGARWIEMV
Mb1966c|M.bovis_AF2122/97 ADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIGELAQRAAMSPRHFT
Rv1931c|M.tuberculosis_H37Rv ADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIGELAQRAAMSPRHFT
MMAR_2855|M.marinum_M AAPVWMP--RAKRPSIRDVQEA--IEAQPGGPHSIEELAHRAAMSPRHFT
MUL_2902|M.ulcerans_Agy99 AAPVWMP--RAKRPSIRDVQEA--IEAQPGGPHSIEELAHRAAMSPRHFT
MAB_0767c|M.abscessus_ATCC_199 SSSHAEPGWLTAAMDPRLAPVLTAIHNNLEHPWSIAELAQHARQSRSAFT
. : .
Mvan_0236|M.vanbaalenii_PYR-1 SEYA-VAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRGLARTMLA
Mflv_0432|M.gilvum_PYR-GCK SEYA-AAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRELVRAMLA
MSMEG_0307|M.smegmatis_MC2_155 SEYS-TAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRGLARAMLS
TH_1906|M.thermoresistible__bu QSCS-AAGKLGDTVIDALCDPPESFPLYGIIAHVLTFSALRRGLARAMLA
Mb1966c|M.bovis_AF2122/97 RVFSDEVGEAPGRYVERIRTEAARRQLEETHDTVVAIAAR-CGFGTAETM
Rv1931c|M.tuberculosis_H37Rv RVFSDEVGEAPGRYVERIRTEAARRQLEETHDTVVAIAAR-CGFGTAETM
MMAR_2855|M.marinum_M RVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVAIAAR-CGFGTAETM
MUL_2902|M.ulcerans_Agy99 RVFTGEVGEAPGRYVERVRTEAARRQLEETEDTVVAIAAR-CGFGTAETM
MAB_0767c|M.abscessus_ATCC_199 QRFTELLGQPPAAYIGERRLDRAAHLLRSTTDPVRQIGRA-VGYTSDAAF
: *. : * * .
Mvan_0236|M.vanbaalenii_PYR-1 GHGVTTRLGDPLDWMRGN----
Mflv_0432|M.gilvum_PYR-GCK GHGVPTGLGDPLDWMRGR----
MSMEG_0307|M.smegmatis_MC2_155 RHGIDTHRGDPLEWMRRD----
TH_1906|M.thermoresistible__bu HHGVRTHHGDPLAWMRSN----
Mb1966c|M.bovis_AF2122/97 RRSFIRRVGISPDQYRKAFA--
Rv1931c|M.tuberculosis_H37Rv RRSFIRRVGISPDQYRKAFA--
MMAR_2855|M.marinum_M RRNFIRRVGISPDQYRKAFA--
MUL_2902|M.ulcerans_Agy99 RRNFIRRVGISPDQYRKAFA--
MAB_0767c|M.abscessus_ATCC_199 SRAFQRRFGEPPLRWRTHHRSG
: . * . *