For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NDPARRDRLRELLDAVTDAGNSGVGDMARSTYASEFHFSREVRRLTGEAPAALRRRVMLERAAWRLQHGE PVSAVAADEGWSSPEVFSRAFRRTYGVPPSQAVDVHFRLPSPNGLHFHPPQSLWLDSDRSDDPGVPDIAA LMIAHDIDDTAYLLTRAAELTRAQWTAEVAPGQTVLEWDGPEPSVGAVLGALVWNKEVWLATIAGEDFPS RAATQPDLVDARTLAAHHDDIAKRWRAMISEYAAAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRR ELVRAMLAGHGVPTGLGDPLDWMRGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0432 | - | - | 100% (307) | helix-turn-helix domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2899 | - | 2e-08 | 36.04% (111) | helix-turn-helix domain-containing protein |
| M. gilvum PYR-GCK | Mflv_5267 | - | 2e-07 | 32.67% (101) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 2e-05 | 32.53% (83) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1931c | - | 2e-05 | 32.53% (83) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0942 | - | 3e-06 | 32.67% (101) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 9e-06 | 31.68% (101) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0307 | - | 1e-125 | 71.62% (303) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_1906 | - | 1e-113 | 66.23% (302) | transcriptional regulator, AraC family protein |
| M. ulcerans Agy99 | MUL_2902 | - | 5e-06 | 31.68% (101) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0236 | - | 1e-147 | 83.28% (305) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0432|M.gilvum_PYR-GCK -----------MNDP-----------------------------------
Mvan_0236|M.vanbaalenii_PYR-1 MTDDPSPEHAALPDPSALRASAHPDPSALRASAHPDPS-----------A
MSMEG_0307|M.smegmatis_MC2_155 ------------MEP-----------------------------------
TH_1906|M.thermoresistible__bu -----------VSEQ-----------------------------------
Mb1966c|M.bovis_AF2122/97 --------MVIVGFPG----------------------------------
Rv1931c|M.tuberculosis_H37Rv --------MVIVGFPG----------------------------------
MMAR_2855|M.marinum_M ----MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEG---GYDVALASI
MUL_2902|M.ulcerans_Agy99 ----MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEG---GYDVALASI
MAB_0942|M.abscessus_ATCC_1997 ----MRRSVVILGFPGVQALDLVGPYEVFATASRHMTGTTPGYDVKLVSA
Mflv_0432|M.gilvum_PYR-GCK -----ARRDRLRELLDAVTDA-GNSGVGDMARSTYASEFHFSREVRRLTG
Mvan_0236|M.vanbaalenii_PYR-1 LRASAHRRDRLRELLDAVTDS-ANADVGDMARSSYASEFHFSREVRRLTG
MSMEG_0307|M.smegmatis_MC2_155 -----NGRDRLRELLDAVVDS-ENDGVGDMARNSYASEFHFSREVRRLTG
TH_1906|M.thermoresistible__bu ---ALTGRDRLRELLDAVVDA-ANTDVESMARSSHFSEFHFSREVRRLAG
Mb1966c|M.bovis_AF2122/97 -------------------DP---VDTVILPGGAGVDAARSEPALIDWVK
Rv1931c|M.tuberculosis_H37Rv -------------------DP---VDTVILPGGAGVDAARSEPALIDWVK
MMAR_2855|M.marinum_M DERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVK
MUL_2902|M.ulcerans_Agy99 DERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVK
MAB_0942|M.abscessus_ATCC_1997 DGAPVSTGSGMELVTQPLPDPEPGCDTLLLPGGIGVSAVQRDAALMSWVR
*. .. :. . . : . : .
Mflv_0432|M.gilvum_PYR-GCK EAPAALRRRVMLERAAWRLQHGEPVSAVAADEGWSSPEVFSRAFRRTYGV
Mvan_0236|M.vanbaalenii_PYR-1 ESPAALRRRVMLERAAWRLQRGEAVSAVAADEGWSSAEVFSRAFRRMYGL
MSMEG_0307|M.smegmatis_MC2_155 EPPAALRRRIMLERAAWRLRQGAGVAEVAAAEGWSSPEVFSRAFRRAFGV
TH_1906|M.thermoresistible__bu EPPAAMRRRVMLERAAWRLQRGESVSAVAAAEGWSSAEVFSRAFRRAFGV
Mb1966c|M.bovis_AF2122/97 AVSGTARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFRPR-IS
Rv1931c|M.tuberculosis_H37Rv AVSGTARRVVTVCTGAFLAAEAGLLG--RTPSDDALG--LCRTFRPR-IS
MMAR_2855|M.marinum_M AAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVD
MUL_2902|M.ulcerans_Agy99 AAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVD
MAB_0942|M.abscessus_ATCC_1997 AAARGARRVVSVCNGAFLAAEAGLLDGCRATTHWAIAGQLASEFPSVTVD
. ** : : .:: .. : : : :. *
Mflv_0432|M.gilvum_PYR-GCK PPSQAVDVHFRLPSPNGLHFHPPQSLWLDSDRSD--DPG--VPDIAALMI
Mvan_0236|M.vanbaalenii_PYR-1 PPSQASDVHFRLPAPNGLHFHPPQSLWLDSDPGDRTPPGMHTPDIAQLMI
MSMEG_0307|M.smegmatis_MC2_155 PPSRATDVGFRLPAPNGVHFHPPRSLWCDGRAGG---GG---PDIAQFML
TH_1906|M.thermoresistible__bu PPSRVAEVHYLLPAPNGVHFHPPHALWVDGPGSRGAPAG-SVPEISAVLV
Mb1966c|M.bovis_AF2122/97 GRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTG--------RRRPRHRD
Rv1931c|M.tuberculosis_H37Rv GRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTG--------RRRPRHRD
MMAR_2855|M.marinum_M PDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHG--------TEIAQTVA
MUL_2902|M.ulcerans_Agy99 PDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHG--------TEIAQTVA
MAB_0942|M.abscessus_ATCC_1997 PDPIFIRSSDKTWTAAGVTAGIDLALALVEEDHG--------AEVAQAVA
. . *: .
Mflv_0432|M.gilvum_PYR-GCK AHDIDDTAYLLTRAAELTRAQWTAEVAPGQ-TVLEWDGPEPSVGAVLGAL
Mvan_0236|M.vanbaalenii_PYR-1 DHDIADTSHLLGQAALLSPQQWVAEVAPGQ-TVLEWDGPEPSVGAVLGAI
MSMEG_0307|M.smegmatis_MC2_155 VHDIADTAYLIEQAYALTENQWRQEVSPGQ-TVLDWDGPEPSVAAVLAAI
TH_1906|M.thermoresistible__bu DHDVADTDYLLECACTLTDRQWAEEISPGQ-QVLAWDGPEPSVGAVLGAI
Mb1966c|M.bovis_AF2122/97 CPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAH
Rv1931c|M.tuberculosis_H37Rv CPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRGRAGGAH
MMAR_2855|M.marinum_M RWLVLYLRRPGGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGPH
MUL_2902|M.ulcerans_Agy99 RWLVLYLRRPCGQ-TQFAAPVWMP--RAKRPSIRDVQEA--IEAQPGGPH
MAB_0942|M.abscessus_ATCC_1997 RWLVLYLRRPGGQ-SQFAAPVWMP--RAKRMPIRDVQEA--IEAEPSGSH
: . : . . ..
Mflv_0432|M.gilvum_PYR-GCK VWNKEVWLATIAGEDFPSRAATQPDLVDARTLAAHHDDIAKRWRAMISEY
Mvan_0236|M.vanbaalenii_PYR-1 VWTKQVWLATIAGDDFPSRACTQPEFVDAATLAAHHDDVGNRWRAMVSEY
MSMEG_0307|M.smegmatis_MC2_155 VWTKEVWLATIEGRDFPSRDTTCN--ASPRELAVHHDTVGNRWTTVISEY
TH_1906|M.thermoresistible__bu VWTKQVWLATIEGADFPTRQHLPP-----SALRDHHRDVGARWIEMVQSC
Mb1966c|M.bovis_AF2122/97 RIGELAQRAAMSPRHFT------------RVFSDEVGEAPGRYVERIRTE
Rv1931c|M.tuberculosis_H37Rv RIGELAQRAAMSPRHFT------------RVFSDEVGEAPGRYVERIRTE
MMAR_2855|M.marinum_M SIEELAHRAAMSPRHFT------------RVFTGEVGEAPRQYVERVRTE
MUL_2902|M.ulcerans_Agy99 SIEELAHRAAMSPRHFT------------RVFTGEVGEAPGRYVERVRTE
MAB_0942|M.abscessus_ATCC_1997 RVPELARLAAMSPRHFT------------RVFTAEVGEAPSAYVERIRSE
: . *:: .*. : . : :
Mflv_0432|M.gilvum_PYR-GCK AAAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRELVRAMLAGHGV
Mvan_0236|M.vanbaalenii_PYR-1 AVAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRGLARTMLAGHGV
MSMEG_0307|M.smegmatis_MC2_155 STAGRLGDTVIDALCDPPESFQLYGIVAHVLTYSAHRRGLARAMLSRHGI
TH_1906|M.thermoresistible__bu SAAGKLGDTVIDALCDPPESFPLYGIIAHVLTFSALRRGLARAMLAHHGV
Mb1966c|M.bovis_AF2122/97 AARRQLEETHDTVVAIAARCG--FGTAETMRRSFIRRVGISPDQYRKAFA
Rv1931c|M.tuberculosis_H37Rv AARRQLEETHDTVVAIAARCG--FGTAETMRRSFIRRVGISPDQYRKAFA
MMAR_2855|M.marinum_M AARRQLEETEDTVVAIAARCG--FGTAETMRRNFIRRVGISPDQYRKAFA
MUL_2902|M.ulcerans_Agy99 AARRQLEETEDTVVAIAARCG--FGTAETMRRNFIRRVGISPDQYRKAFA
MAB_0942|M.abscessus_ATCC_1997 AARRQLEETDDTMVVIAGRCG--FGSAESLRRNFVRRMGVSPDQYRKTFQ
:. :* :* : . .. :* : * :
Mflv_0432|M.gilvum_PYR-GCK PTGLGDPLDWMRGR
Mvan_0236|M.vanbaalenii_PYR-1 TTRLGDPLDWMRGN
MSMEG_0307|M.smegmatis_MC2_155 DTHRGDPLEWMRRD
TH_1906|M.thermoresistible__bu RTHHGDPLAWMRSN
Mb1966c|M.bovis_AF2122/97 --------------
Rv1931c|M.tuberculosis_H37Rv --------------
MMAR_2855|M.marinum_M --------------
MUL_2902|M.ulcerans_Agy99 --------------
MAB_0942|M.abscessus_ATCC_1997 RTDRSSV-------