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NASVPTFESILAPSARRWTSGRVRFGLLGSYPPSTSGVATFGSALAAALTARGSEVSVVRIADGSESPDA GVIGELVKGSPQSVTACVESLNGSEVAVIQHQQGLYGGTHGDEVLAILGGLRVPSIVIVHDVSKSPEPHQ RWVLEQIVTMADSVVVMSEAARARLRGEYGVDGHKIVVIPHGAVLPTQPRLKRGSRPVILSFGLLGPGKG VEHVIDAMPSLLSVAGRPRYVVAGRTHPEVLARDGEAYREARVEQARAGGVADSVSFDDRYLDRASLAAL IQTAAVIVLPFDSKDQVTSGVLVDAVASGRPVVATAFPHAVELLCDGAGIVVPHDDPQALTAALRRVLSQ PRLAGSMAAEARQLAPTMAWPVVADAYAQLAARVVGERQMRM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5224 | - | - | 100% (393) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_5216 | - | e-120 | 57.52% (379) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_4262 | - | 2e-14 | 30.74% (257) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0496 | - | 2e-07 | 28.09% (267) | mannosyltransferase |
| M. tuberculosis H37Rv | Rv0486 | - | 2e-07 | 28.09% (267) | mannosyltransferase |
| M. leprae Br4923 | MLBr_00452 | - | 3e-09 | 28.19% (227) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_1019c | - | 4e-11 | 28.40% (257) | glycosyl transferase |
| M. marinum M | MMAR_1681 | - | 9e-12 | 29.59% (267) | transferase |
| M. avium 104 | MAV_3879 | - | 3e-15 | 29.89% (271) | glycosyl transferase, group 1 family protein |
| M. smegmatis MC2 155 | MSMEG_1207 | - | 1e-120 | 57.33% (375) | glycosyltransferase, group I |
| M. thermoresistible (build 8) | TH_1111 | - | 4e-10 | 28.21% (280) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1919 | - | 5e-12 | 29.59% (267) | transferase |
| M. vanbaalenii PYR-1 | Mvan_1042 | - | 1e-150 | 71.35% (370) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1681|M.marinum_M -------MKILMVSWEYPPVVIGGLG-RHVHHLATALVAAGHEVVVLSRR
MUL_1919|M.ulcerans_Agy99 -------MKILMVSWEYPPVVIGGLG-RHVHHLATALVAAGHEVVVLSRR
MAV_3879|M.avium_104 -------MKILMVSWEYPPVVIGGLG-RHVHHLSTALAAAGHDVVVLSRR
Mb0496|M.bovis_AF2122/97 MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL
Rv0486|M.tuberculosis_H37Rv MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL
Mflv_5224|M.gilvum_PYR-GCK ----------MNASVPTFESILAPSARRWTSGRVRFGLLGSYPPSTSGVA
Mvan_1042|M.vanbaalenii_PYR-1 ----------MKRPIP---------------RTVRFGLLSTYPPTPCRLA
MSMEG_1207|M.smegmatis_MC2_155 ----------MTTASAWPLTP-GVATRQGCSDGLNVGILSTYAPTACGLA
MAB_1019c|M.abscessus_ATCC_199 -----------------------------------MTGSEWFSSLPGGLN
TH_1111|M.thermoresistible__bu ----------------------------VTGVSRVLLVTNDFPPRPGGIQ
MLBr_00452|M.leprae_Br4923 --------------------------------MRIGMICPYSFDVPGGVQ
MMAR_1681|M.marinum_M PSGTDPSTHPSS--------------------DLISEGVRVIAAAQDPHE
MUL_1919|M.ulcerans_Agy99 PSGTDPSTHPSS--------------------DLISEGVRVIAAAQDPHE
MAV_3879|M.avium_104 PTGTDPRTHPST--------------------DQISEGVRVIAAAQDPHE
Mb0496|M.bovis_AF2122/97 AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV
Rv0486|M.tuberculosis_H37Rv AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV
Mflv_5224|M.gilvum_PYR-GCK TFGSALAAALTAR-------------------GSEVSVVRIADGSESPDA
Mvan_1042|M.vanbaalenii_PYR-1 NYSSALFGALSAR-------------------GSQVSVVRVADGSQSSDA
MSMEG_1207|M.smegmatis_MC2_155 TFSAALAGGLSGT-------------------GANVNVVRIADGAPSGNA
MAB_1019c|M.abscessus_ATCC_199 RYFTDLFTALRTR--------------------GDIELSAAAFGVPSDGG
TH_1111|M.thermoresistible__bu SYLHELVLRLVRT---------------------QSHVVTVYAPRWRGSD
MLBr_00452|M.leprae_Br4923 SHVLQLAEVMRAR-------------------GQQVRVLAPASPDVSLPE
MMAR_1681|M.marinum_M FSFGSDMMAWTLAMG--HAMVRAGLT--LSG--PGAEQ------PWQPDI
MUL_1919|M.ulcerans_Agy99 FSFGSDMMAWTLAMG--HAMVRAGLT--LSG--PGAEQ------PWQPDI
MAV_3879|M.avium_104 FTFGTDMMAWTLAMG--HAMIRAGLPPKLHDKKPGGNR------PWRPDV
Mb0496|M.bovis_AF2122/97 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI
Rv0486|M.tuberculosis_H37Rv VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI
Mflv_5224|M.gilvum_PYR-GCK GVIG------ELVKG--SPQSVTACVESLNGSEVAVIQ----------HQ
Mvan_1042|M.vanbaalenii_PYR-1 RIVG------ELVNG--SARSAAHCVDSLNHSDVAVIQ----------HD
MSMEG_1207|M.smegmatis_MC2_155 RVVG------ELVNG--SAASTAACVELLNQNHVAIVQ----------HE
MAB_1019c|M.abscessus_ATCC_199 SSWG----------G--TGGSTRSRVLAAFNDRSGLQQ---------PGI
TH_1111|M.thermoresistible__bu DFDAEAARTGYRVVR--HPGTLMLPEPSVARRMRRLIR--------DEGI
MLBr_00452|M.leprae_Br4923 YVVSAGRAIPIPYNG---SVARLQFSPAVHSRVRRWLVDG------DFDV
.
MMAR_1681|M.marinum_M VHAHDWLVAHPAIALADYYDVPMVSTIHATEAGRHSGWVSG--DLSRQVH
MUL_1919|M.ulcerans_Agy99 VHAHDWLVAHPAIALADYYDVPMVSTIHATEAGRHSGWVSG--DLSRQVH
MAV_3879|M.avium_104 VHAHDWLVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSG--PISRQVH
Mb0496|M.bovis_AF2122/97 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT
Rv0486|M.tuberculosis_H37Rv VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT
Mflv_5224|M.gilvum_PYR-GCK QGLYGGTHGDEVLAILGGLRVPSIVIVHDVSKS----------PEPHQRW
Mvan_1042|M.vanbaalenii_PYR-1 YGVYGGAHGDGLLDVIDGLRVPTVAVAHTILKN----------PAPHQRW
MSMEG_1207|M.smegmatis_MC2_155 YGIYGGADGDEVVGIIGALDVPVIVVLHTVPSA----------PTAHQRA
MAB_1019c|M.abscessus_ATCC_199 LDRHFCLYGPAAIGWGTRSRLVVHFHGPWAAESRFAGAGP---LRARAKY
TH_1111|M.thermoresistible__bu DTVWFGAAAPLALLAGTARAAGARRVLASTHGHEVG------WSMLPVAR
MLBr_00452|M.leprae_Br4923 LHLHEPNAPSLSMWALRVAEGPIVATFHTSTTKS---------LTLSVFQ
MMAR_1681|M.marinum_M AVESWLVRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDAARWPFA
MUL_1919|M.ulcerans_Agy99 AVESWLVRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDVARWPFA
MAV_3879|M.avium_104 AIESWLVRESDSLITCSASMADEITELFGPGLAQITVIRNGIETARWPFA
Mb0496|M.bovis_AF2122/97 VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG
Rv0486|M.tuberculosis_H37Rv VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG
Mflv_5224|M.gilvum_PYR-GCK VLEQ-IVTMADSVVVMSEAARARLRGEYGVDGHKIVVIPHGAVLPTQPRL
Mvan_1042|M.vanbaalenii_PYR-1 VMER-MAATIDRMVVMSEAARERLCREYGVDRRKVVTIPYGAVLPTGPRA
MSMEG_1207|M.smegmatis_MC2_155 VLEQ-VAALAARVVVMSASASRRLCRDFRVDRRKVITIPHGATLPCGPVL
MAB_1019c|M.abscessus_ATCC_199 VVERLRYAGAERVIVLSDRFRDVLVEDYRIPTDRIEVIPPGVDLDRFGVL
TH_1111|M.thermoresistible__bu HALRIIGDNTDVLTYVSRYTRRRFASAFGP-RAGLEHVPPGVDIDRFAPD
MLBr_00452|M.leprae_Br4923 GVLRPWHEKIIGRIAVSDLARRWQMEALGS---DAVEIPNGVNVDSLSSA
: : *
MMAR_1681|M.marinum_M VRKPRTGPP--------ELLYVGRLEY-EKGVHNAIAALPRIRRAHPGTT
MUL_1919|M.ulcerans_Agy99 VRKPRTGPP--------ELLYVGRLEY-EKGVHNAIAALPRIRRAHPGTT
MAV_3879|M.avium_104 PRRPRTGPA--------ELLYLGRLEY-EKGVHDVIAALPRIRRTHPGTT
Mb0496|M.bovis_AF2122/97 DRRAARAALGLPV-DERVVAFVGRIQP-LKAPDIVLRAAAKLPGVRIIVA
Rv0486|M.tuberculosis_H37Rv DRRAARAALGLPV-DERVVAFVGRIQP-LKAPDIVLRAAAKLPGVRIIVA
Mflv_5224|M.gilvum_PYR-GCK KRGSRPVILSFG--LLGPGKGVEHVID-AMPSLLSVAGRPRYVVAGRTHP
Mvan_1042|M.vanbaalenii_PYR-1 KRGSRPTILTCG--LLGPGKGVERVID-VMSSLQSVPGHPRYVVAGRTHP
MSMEG_1207|M.smegmatis_MC2_155 KRGGRPTLLTWG--LLGPGKGIERGID-AMSVLRRLNGMPRYLIAGLTHP
MAB_1019c|M.abscessus_ATCC_199 PRLDAPTGR-------RTVLCVRRLEH-RMGIHRLIESWPTVVSAHPDAC
TH_1111|M.thermoresistible__bu PVARTALRTRYRLGERPVVLCLSRLVP-RKGQDMLIRALPMIRRRVGDAV
MLBr_00452|M.leprae_Br4923 PQLAGYPRLG------KTVLFLGRYDEPRKGMSVLLDALPGVMECFDDVQ
: : : . .
MMAR_1681|M.marinum_M LTIAGEG-TQQDWLVEQARKHRVLKATKFLG-HLEHAELLTLLHRADAAV
MUL_1919|M.ulcerans_Agy99 LTIAGEG-TQQDWLVEQARKHRVLKATKFLG-HLEHAELLTLLHRADAAV
MAV_3879|M.avium_104 LTIAGEG-TQQGWLIEQARKHRVLKAIRFVG-HLEHSELLAMLHRADAAV
Mb0496|M.bovis_AF2122/97 GGPSGSGLASPDGLVRLADELGISARVTFLP-PQSHTDLATLFRAADLVA
Rv0486|M.tuberculosis_H37Rv GGPSGSGLASPDGLVRLADELGISARVTFLP-PQSHTDLATLFRAADLVA
Mflv_5224|M.gilvum_PYR-GCK EVLARDGEAYREARVEQARAGGVADSVSFDDRYLDRASLAALIQTAAVIV
Mvan_1042|M.vanbaalenii_PYR-1 KVLARDGEAYREARIEQARRLGVADSVTFEDRHLDRASLAALFQAAAVIV
MSMEG_1207|M.smegmatis_MC2_155 KVLAAEGEAYRDACVERARSTGVSDAVYFDPGYQSASSLTTLVQAAKVVL
MAB_1019c|M.abscessus_ATCC_199 LMIVGTGTAEKDLRAQVAAAG-LDDSVHFTG-RVDDLTLTQLYTLADFTV
TH_1111|M.thermoresistible__bu LVIVGGG-PYRTALQRLAHRYDVAAHVVFTG-GIPAEELPAHHAMADVFA
MLBr_00452|M.leprae_Br4923 LLIVGRG----DEEQLRSQAGGLVEHIRFLG-QVDDAGKAAAMRSADVYC
* : : * *
MMAR_1681|M.marinum_M FP-------SHYEPFGLVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSC
MUL_1919|M.ulcerans_Agy99 FP-------SHYEPFGLVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSC
MAV_3879|M.avium_104 LP-------SHYEPFGIVALEAAAAGTPLVTSNIGGLGEAVIDGQTGVSC
Mb0496|M.bovis_AF2122/97 VP-------SYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITGTLV
Rv0486|M.tuberculosis_H37Rv VP-------SYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITGTLV
Mflv_5224|M.gilvum_PYR-GCK LPF-----DSKDQVTSGVLVDAVASGRPVVATAFPHAVELLCDG-AGIVV
Mvan_1042|M.vanbaalenii_PYR-1 LPY-----DSTDQVTSGALVDAVASGRPVVATAFPHAVEVLRDG-AGILV
MSMEG_1207|M.smegmatis_MC2_155 LPY-----DSTEQVTSGVLVDAIAHGRPVVATAFPHAVELLSSG-AGIVV
MAB_1019c|M.abscessus_ATCC_199 VP------SVALEGFGLIALESLATGRPAVVTDCGGLPDAVRGLDSSLIV
TH_1111|M.thermoresistible__bu MPCRTRGAGLDVEGLGIVYLEASATGVPVVAGRSGGAPETVRHGETGLVV
MLBr_00452|M.leprae_Br4923 APN------IGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGHLV
* : . ::: * * * *. : .
MMAR_1681|M.marinum_M PPRDVAALAAAVCGVLDDPAAAQQRAR-AARERLNSDFDWQTVAEQTAQV
MUL_1919|M.ulcerans_Agy99 PPRDVAALAAAVCGVLDDPAAAQQRAR-AARERLNSNFDWQTVAEQTAQV
MAV_3879|M.avium_104 PPRDVPALAAAIRTVLDDPEAAQRRAC-AARERLTSDFDWHTVADKTAQV
Mb0496|M.bovis_AF2122/97 SGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDALLAS
Rv0486|M.tuberculosis_H37Rv SGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDALLAS
Mflv_5224|M.gilvum_PYR-GCK PHDDPQALTAALRRVLSQPRLAG--SMAAEARQLAPTMAWPVVADAYAQL
Mvan_1042|M.vanbaalenii_PYR-1 PHDDPEALSCALRRVLTQPRLAG--SLAAEARQLAPAMAWPVVADTYLEL
MSMEG_1207|M.smegmatis_MC2_155 DHDDPDALVSALRSVITQPRLAG--AMAAEARRIAPSMAWSVVANAYQTV
MAB_1019c|M.abscessus_ATCC_199 PADNAEALAARLVSALDGALPDP-----AQCRQHAESFSWAAAAQRHHAV
TH_1111|M.thermoresistible__bu DGRDVREIATAVGDLLSDPDRAAAMG-AAGRQWVVQQWQWQTQADRLARL
MLBr_00452|M.leprae_Br4923 PAGDSAALADALVALLRNDVLRER--YVAAGAEAVRRYDWSVVASQIMRV
: : : * :.
MMAR_1681|M.marinum_M YLAAK---RGERQ--------PLPRLPIVEHALPDR----
MUL_1919|M.ulcerans_Agy99 YLAAK---RGERQ--------PLPRLPIVEHALPDR----
MAV_3879|M.avium_104 YLSAK---RAERQ--------PQARLPIVEHALPDR----
Mb0496|M.bovis_AF2122/97 YRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA
Rv0486|M.tuberculosis_H37Rv YRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA
Mflv_5224|M.gilvum_PYR-GCK AARVVGERQMRM----------------------------
Mvan_1042|M.vanbaalenii_PYR-1 AARLLTERQLRV----------------------------
MSMEG_1207|M.smegmatis_MC2_155 ARELLTGRPRQR----------------------------
MAB_1019c|M.abscessus_ATCC_199 YAELSA----------------------------------
TH_1111|M.thermoresistible__bu LQV-------------------------------------
MLBr_00452|M.leprae_Br4923 YETVATSGSKVQVAS-------------------------