For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KILMVSWEYPPVVIGGLGRHVHHLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPH EFSFGSDMMAWTLAMGHAMVRAGLTLSGPGAEQPWQPDIVHAHDWLVAHPAIALADYYDVPMVSTIHATE AGRHSGWVSGDLSRQVHAVESWLVRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDAARWPFAVRK PRTGPPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEGTQQDWLVEQARKHRVLKATKFLGHL EHAELLTLLHRADAAVFPSHYEPFGLVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAA VCGVLDDPAAAQQRARAARERLNSDFDWQTVAEQTAQVYLAAKRGERQPLPRLPIVEHALPDR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1681 | - | - | 100% (414) | transferase |
M. marinum M | MMAR_0812 | - | 1e-29 | 29.52% (393) | mannosyltransferase |
M. marinum M | MMAR_4226 | - | 7e-29 | 28.40% (419) | glycosyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3058 | - | 0.0 | 86.71% (414) | transferase |
M. gilvum PYR-GCK | Mflv_4262 | - | 0.0 | 76.33% (414) | glycosyl transferase, group 1 |
M. tuberculosis H37Rv | Rv3032 | - | 0.0 | 86.71% (414) | transferase |
M. leprae Br4923 | MLBr_01715 | - | 0.0 | 84.06% (414) | putative transferase |
M. abscessus ATCC 19977 | MAB_3366 | - | 0.0 | 74.70% (415) | glycosyltransferase |
M. avium 104 | MAV_3879 | - | 0.0 | 83.73% (418) | glycosyl transferase, group 1 family protein |
M. smegmatis MC2 155 | MSMEG_0933 | - | 5e-30 | 28.89% (405) | hypothetical protein MSMEG_0933 |
M. thermoresistible (build 8) | TH_2191 | - | 0.0 | 79.57% (416) | POSSIBLE TRANSFERASE |
M. ulcerans Agy99 | MUL_1919 | - | 0.0 | 99.52% (414) | transferase |
M. vanbaalenii PYR-1 | Mvan_2096 | - | 0.0 | 77.24% (413) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4262|M.gilvum_PYR-GCK ----------------------MKMKILLVSWEYPPVVIG------GLGR Mvan_2096|M.vanbaalenii_PYR-1 ----------------------MKTKILLVSWEYPPVVIG------GLGR MMAR_1681|M.marinum_M ------------------------MKILMVSWEYPPVVIG------GLGR MUL_1919|M.ulcerans_Agy99 ------------------------MKILMVSWEYPPVVIG------GLGR Mb3058|M.bovis_AF2122/97 ------------------------MRILMVSWEYPPVVIG------GLGR Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYPPVVIG------GLGR MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIG------GLGR MAV_3879|M.avium_104 ------------------------MKILMVSWEYPPVVIG------GLGR TH_2191|M.thermoresistible__bu ------------------------MKILMVSWEYPPVVVG------GLGR MAB_3366|M.abscessus_ATCC_1997 ------------------------MRILMVSWEYPPVVIG------GLGR MSMEG_0933|M.smegmatis_MC2_155 --------------MRLATDLETPRRVAVLSVHTSPLAQPGTGDAGGMNV :: ::* . .*:. *:. Mflv_4262|M.gilvum_PYR-GCK HVHHLATELVAAGHEVVVLSRRPTGTDPQTHPTTDETHEGVRVIAAAEDP Mvan_2096|M.vanbaalenii_PYR-1 HVHHLATELAQSGHEVVVLSRRPTATDPQTHPTTDEVHEGVRVIAAAEDP MMAR_1681|M.marinum_M HVHHLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDP MUL_1919|M.ulcerans_Agy99 HVHHLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDP Mb3058|M.bovis_AF2122/97 HVHHLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDP Rv3032|M.tuberculosis_H37Rv HVHHLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDP MLBr_01715|M.leprae_Br4923 HVHHLSTALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDP MAV_3879|M.avium_104 HVHHLSTALAAAGHDVVVLSRRPTGTDPRTHPSTDQISEGVRVIAAAQDP TH_2191|M.thermoresistible__bu HVYHLSTALAAAGHEVVVLSRRPTGTDPSTHPSTDEVRDGVRVLAAAQDP MAB_3366|M.abscessus_ATCC_1997 HVHHLSTELAAAGHDVVVLTRRPSGTDPSSHPTSDEISEGVRVVAAAEDP MSMEG_0933|M.smegmatis_MC2_155 YVLQTALQLARRGVEVEVFTRATSSADAPVVP----VAPGVLVRNVVAGP :* : : *. * :* *::* .:.:*. * ** * .. .* Mflv_4262|M.gilvum_PYR-GCK HEFGFGTDMMAWVLAMGHSMIRAGFG----------LDGWRPDIVHAHDW Mvan_2096|M.vanbaalenii_PYR-1 HEFTFGTDMMAWTLAMGHAMIRAGLV----------LADWRPDIVHAHDW MMAR_1681|M.marinum_M HEFSFGSDMMAWTLAMGHAMVRAGLT----LSGPGAEQPWQPDIVHAHDW MUL_1919|M.ulcerans_Agy99 HEFSFGSDMMAWTLAMGHAMVRAGLT----LSGPGAEQPWQPDIVHAHDW Mb3058|M.bovis_AF2122/97 HEFTFGNDMMAWTLAMGHAMIRAGLR----LKKLGTDRSWRPDVVHAHDW Rv3032|M.tuberculosis_H37Rv HEFTFGNDMMAWTLAMGHAMIRAGLR----LKKLGTDRSWRPDVVHAHDW MLBr_01715|M.leprae_Br4923 HEFTFSNDMMAWTLAMGHAMIRTGLS----LTRHSSDLPWRPDVVHAHDW MAV_3879|M.avium_104 HEFTFGTDMMAWTLAMGHAMIRAGLPPKLHDKKPGGNRPWRPDVVHAHDW TH_2191|M.thermoresistible__bu HEFDFGRDMMAWTLAMGHSMVRAGLALG--LRGGTGGTPWQPDVVHAHDW MAB_3366|M.abscessus_ATCC_1997 HDFDFGTDMMAWTLAMGHAMVRAGLALG-----LKGSGDWRPDVVHAHDW MSMEG_0933|M.smegmatis_MC2_155 FEGLDKNDLPTQLCAFTAGVLRAEAT----------HEPGYYDVVHSHYW .: *: : *: .::*: *:**:* * Mflv_4262|M.gilvum_PYR-GCK LVAHPAVALAQFFDVPLVSTIHATEAGRHSGWVSGSVSR--QVHALESWL Mvan_2096|M.vanbaalenii_PYR-1 LVATPAVALAQFFDVPLVSTIHATEAGRHSGWVSGQVSR--QVHALESWL MMAR_1681|M.marinum_M LVAHPAIALADYYDVPMVSTIHATEAGRHSGWVSGDLSR--QVHAVESWL MUL_1919|M.ulcerans_Agy99 LVAHPAIALADYYDVPMVSTIHATEAGRHSGWVSGDLSR--QVHAVESWL Mb3058|M.bovis_AF2122/97 LVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSR--QVHAVESWL Rv3032|M.tuberculosis_H37Rv LVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSR--QVHAVESWL MLBr_01715|M.leprae_Br4923 LVAHPAITLAQFYDVPMVSTIHATEAGRHSGWVSGALSR--QVHAVESWL MAV_3879|M.avium_104 LVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGPISR--QVHAIESWL TH_2191|M.thermoresistible__bu LVAHPAIALAEFFDVPLVSTIHATEAGRHSGWVSGPISR--QVHAVESWL MAB_3366|M.abscessus_ATCC_1997 LVAHPAIALAEHFDVPLVSTLHATEAGRHSGWVSGRISR--QVHSVEWWL MSMEG_0933|M.smegmatis_MC2_155 LSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAAGDAPEPPLRAVGEQQV * . . : : **:* * *: * :::. .:* .. * : Mflv_4262|M.gilvum_PYR-GCK VRDSDSLITCSASMRDEISALFGPELAEISVIPNGIDTDGWPFAARRAHS Mvan_2096|M.vanbaalenii_PYR-1 VRDSDSLITCSASMRDEITTLFGPELADITVIPNGIDTDGWPFAPHRPRP MMAR_1681|M.marinum_M VRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDAARWPFAVRKPRT MUL_1919|M.ulcerans_Agy99 VRESDSLITCSGSMSDEITELFGPGLAETAVIRNGIDVARWPFAVRKPRT Mb3058|M.bovis_AF2122/97 VRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFAARRPRT Rv3032|M.tuberculosis_H37Rv VRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFAARRPRT MLBr_01715|M.leprae_Br4923 VRESDSLITCSASMCNEIIELFGPGLAEITVIRNGIDPARWPFAARRART MAV_3879|M.avium_104 VRESDSLITCSASMADEITELFGPGLAQITVIRNGIETARWPFAPRRPRT TH_2191|M.thermoresistible__bu VRDSDSLITCSASMSEEITELFGPGLSEIRVIRNGIDVAQWPFARRSPRS MAB_3366|M.abscessus_ATCC_1997 ARESDSLITCSASMLDEVTQLFGPELPQVHVIRNGIDVTRWVFAPRPPAD MSMEG_0933|M.smegmatis_MC2_155 VDEADRLIVNTEVEAQQLVSLHNADRSRIDVVHPGVDLDVFTPGSRDAAR . ::* **. : ::: *... . *: *:: : . : . Mflv_4262|M.gilvum_PYR-GCK G-------PAELLYFGRLEYEKGVHDAIAALPKVRRTHPGTTLTIAGDG- Mvan_2096|M.vanbaalenii_PYR-1 G-------PAELLYFGRLEYEKGVHDLIAALPRIRRAHPGTTLTIAGDG- MMAR_1681|M.marinum_M G-------PPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEG- MUL_1919|M.ulcerans_Agy99 G-------PPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEG- Mb3058|M.bovis_AF2122/97 G-------PAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEG- Rv3032|M.tuberculosis_H37Rv G-------PAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEG- MLBr_01715|M.leprae_Br4923 G-------PAELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEG- MAV_3879|M.avium_104 G-------PAELLYLGRLEYEKGVHDVIAALPRIRRTHPGTTLTIAGEG- TH_2191|M.thermoresistible__bu G-------PPRLLYVGRLEYEKGVQDAIAALPRIRRTHPGTTLTIAGTG- MAB_3366|M.abscessus_ATCC_1997 GT------PPVLLFVGRLEYEKGIHDAIAALPKIRRAHPGTVLAVAGDG- MSMEG_0933|M.smegmatis_MC2_155 AVFGLPTDQKIVAFVGRIQPLKAPDILLRAAAKLPGVRVLIAGGPSGSGL . : :.**:: *. . : * .:: . :* * Mflv_4262|M.gilvum_PYR-GCK TQLGFLTEQARRHKVLKATKFVGRVDHSQLLTLLHRADVAVLPSHYEPFG Mvan_2096|M.vanbaalenii_PYR-1 TQLDFLVEQARKHKVVKATNFIGRVGHSELLRLLHRADAAVLPSHYEPFG MMAR_1681|M.marinum_M TQQDWLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHYEPFG MUL_1919|M.ulcerans_Agy99 TQQDWLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHYEPFG Mb3058|M.bovis_AF2122/97 TQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFG Rv3032|M.tuberculosis_H37Rv TQQDWLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFG MLBr_01715|M.leprae_Br4923 TQQDWLVDQARKYKVIKATRFVGHLNHNELLAALQRADAAVLPSHYEPFG MAV_3879|M.avium_104 TQQGWLIEQARKHRVLKAIRFVGHLEHSELLAMLHRADAAVLPSHYEPFG TH_2191|M.thermoresistible__bu TQHEWLVEQARKHKVLKATRFVGQLGHEALLRQLHTADAAVLPSHYEPFG MAB_3366|M.abscessus_ATCC_1997 TQQDWLLEQARKYKVVKSVQFLGTLDHSELLHWLHHADAILLPSHYEPFG MSMEG_0933|M.smegmatis_MC2_155 AQPDTLVRLADELGISDRVTFLPPQSREQLVNVYRAADLVAVPSYSESFG :* * * . : *: : *: : ** .**: *.** Mflv_4262|M.gilvum_PYR-GCK IVALEAAATGTPLVTSTAGGLGEAVIDGVTGMSYPPSDVIALAAAIRAVL Mvan_2096|M.vanbaalenii_PYR-1 IVALEAAATGTPLVTSTAGGLGEAVIDGVTGLSYPPGDVAALARAVRAVL MMAR_1681|M.marinum_M LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVL MUL_1919|M.ulcerans_Agy99 LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVL Mb3058|M.bovis_AF2122/97 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVL Rv3032|M.tuberculosis_H37Rv LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVL MLBr_01715|M.leprae_Br4923 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVL MAV_3879|M.avium_104 IVALEAAAAGTPLVTSNIGGLGEAVIDGQTGVSCPPRDVPALAAAIRTVL TH_2191|M.thermoresistible__bu IVALEAAATGAPLVTSTAGGLGEAVIDGVTGKSFKPRDIAGLTAAVRAVL MAB_3366|M.abscessus_ATCC_1997 IVALEAAAAGTPLVTSTVGGLGEAVIDGETGMSFAPRDVAGIAEAVTRTL MSMEG_0933|M.smegmatis_MC2_155 LVAVEAQACGTPVVAAAVGGLPVAVADGVSGALVDGHDIGDWADTISEVL :**:** * *:*:*:: *** ** :* :* *: : : .* Mflv_4262|M.gilvum_PYR-GCK DAPAAAQERATAARARLTSDFAWHTVAAETAQVYLAAK--RAERRPQPRR Mvan_2096|M.vanbaalenii_PYR-1 DSPAAAQRRARAARERLTSDFSWHTVAAETAQVYLAAK--RAVRRPQPRR MMAR_1681|M.marinum_M DDPAAAQQRARAARERLNSDFDWQTVAEQTAQVYLAAK--RGERQPLPRL MUL_1919|M.ulcerans_Agy99 DDPAAAQQRARAARERLNSNFDWQTVAEQTAQVYLAAK--RGERQPLPRL Mb3058|M.bovis_AF2122/97 DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAK--RGERQPQPRL Rv3032|M.tuberculosis_H37Rv DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAK--RGERQPQPRL MLBr_01715|M.leprae_Br4923 EDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAK--RRERQPQPRL MAV_3879|M.avium_104 DDPEAAQRRACAARERLTSDFDWHTVADKTAQVYLSAK--RAERQPQARL TH_2191|M.thermoresistible__bu DDPEGAQQRAVAARERLTADFDWHSVAAETAQVYLAAK--RREREPLPRR MAB_3366|M.abscessus_ATCC_1997 DDPAAAAERAVAARARLTADFDWATVADETAQVYLAAK--RREREPLGRS MSMEG_0933|M.smegmatis_MC2_155 DREPAALSRASAEHA---AQFSWAHTVDALLASYSRAMSDYRARHPRPAA : .* ** * : ::* * .. * * *.* Mflv_4262|M.gilvum_PYR-GCK TIVERPLPDR----- Mvan_2096|M.vanbaalenii_PYR-1 PIEERPLPDR----- MMAR_1681|M.marinum_M PIVEHALPDR----- MUL_1919|M.ulcerans_Agy99 PIVEHALPDR----- Mb3058|M.bovis_AF2122/97 PIVEHALPDR----- Rv3032|M.tuberculosis_H37Rv PIVEHALPDR----- MLBr_01715|M.leprae_Br4923 PIVEHALPDR----- MAV_3879|M.avium_104 PIVEHALPDR----- TH_2191|M.thermoresistible__bu LIVEHALPDR----- MAB_3366|M.abscessus_ATCC_1997 VIVERPLPDR----- MSMEG_0933|M.smegmatis_MC2_155 RRSGRRFSMRRGVRT : :. *