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MSDNSTGTKDMTPHFEDIQAHYDLSDDFFGVFQDPTRKYSCAYFTGPNVTLSEAQIANVDQHLDALDLKP GMTLLEVGCGWGLTLQRAMEKYDVNVIGLTLSKNQKAYCDQLLGKLGSERTFDVRLEGWEQFHSPVDRIV SIEAFEHFGFERYDDFFKMCFDVLPEDGRMTIQSSVGYHPYDLAERGKKLTFELARFVKFMITEIFPGGR LPTTQMMVEHGEKAGFTVPQPLSLRNHYIKTLGIWADRLEANKDAAIAATDEENYERYMRYLKGCQYYFI DEAIDVSLVTYLKPAVAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5113 | - | - | 100% (298) | cyclopropane-fatty-acyl-phospholipid synthase |
| M. gilvum PYR-GCK | Mflv_3304 | - | 1e-85 | 52.90% (293) | cyclopropane-fatty-acyl-phospholipid synthase |
| M. gilvum PYR-GCK | Mflv_1800 | - | 3e-84 | 52.63% (285) | cyclopropane-fatty-acyl-phospholipid synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0661c | mmaA4 | 1e-124 | 70.45% (291) | methoxy mycolic acid synthase |
| M. tuberculosis H37Rv | Rv0642c | mmaA4 | 1e-125 | 70.45% (291) | methoxy mycolic acid synthase |
| M. leprae Br4923 | MLBr_01903 | mmaA4 | 1e-121 | 67.69% (294) | methyl mycolic acid synthase 4 |
| M. abscessus ATCC 19977 | MAB_3881 | - | 7e-86 | 55.07% (276) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. marinum M | MMAR_0977 | mmaA4 | 1e-124 | 69.62% (293) | methoxy mycolic acid synthase 4, MmaA4 |
| M. avium 104 | MAV_4517 | - | 1e-123 | 69.39% (294) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. smegmatis MC2 155 | MSMEG_0902 | - | 7e-91 | 55.48% (283) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. thermoresistible (build 8) | TH_1862 | cmaA1 | 1e-143 | 81.69% (284) | CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 1 CMAA1 |
| M. ulcerans Agy99 | MUL_0729 | mmaA4 | 1e-123 | 68.94% (293) | methoxy mycolic acid synthase 4, MmaA4 |
| M. vanbaalenii PYR-1 | Mvan_1239 | - | 1e-168 | 94.30% (298) | cyclopropane-fatty-acyl-phospholipid synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5113|M.gilvum_PYR-GCK -------------MSDNSTGTKDMTPHFEDIQAHYDLSDDFFGVFQDPTR
Mvan_1239|M.vanbaalenii_PYR-1 -------------MSDQSSGTKDMTPHFEDIQAHYDLSDDFFGVFQDPTR
TH_1862|M.thermoresistible__bu -----------------------MRPHFEDIQAHYDLSDDFFGLFQDPTR
Mb0661c|M.bovis_AF2122/97 ----------MTRMAEKPISPTKTRTRFEDIQAHYDVSDDFFALFQDPTR
Rv0642c|M.tuberculosis_H37Rv ----------MTRMAEKPISPTKTRTRFEDIQAHYDVSDDFFALFQDPTR
MMAR_0977|M.marinum_M -------------MAEIPPTPTKTRTRSEDIQAHYDVSDDFFALFQDPTR
MUL_0729|M.ulcerans_Agy99 MRRSCEHQENRTTMAEIPPTPTKMRTRSEDIQAHYDVSDDFFALFQDPTR
MAV_4517|M.avium_104 -------------MAEQPSSPTKTRTRSEDIQAHYDVSDDFFGLFQDPTR
MLBr_01903|M.leprae_Br4923 -------------MTEQPTGPTKTRTRSEDIQAHYDLSNEFFALFQDPTR
MAB_3881|M.abscessus_ATCC_1997 --------------------MSKLTPKFSDVQAHYDLSDDFFALFLDPSR
MSMEG_0902|M.smegmatis_MC2_155 -------------------MRETLTPNFADVQAHYDLSDDFFRLFLDPTQ
.. *:*****:*::** :* **::
Mflv_5113|M.gilvum_PYR-GCK KYSCAYFTGPNVTLSEAQIANVDQHLDALDLKPGMTLLEVGCGWGLTLQR
Mvan_1239|M.vanbaalenii_PYR-1 KYSCAYFTGPDVTLSEAQIANVDQHLDKLDLKPGMTLLEVGCGWGLTLQR
TH_1862|M.thermoresistible__bu KYSCGYFTGPDATLSDAQIADVDLNLDKLDLKPGMTLLDIGCGWGLTLRR
Mb0661c|M.bovis_AF2122/97 TYSCAYFEPPELTLEEAQYAKVDLNLDKLDLKPGMTLLDIGCGWGTTMRR
Rv0642c|M.tuberculosis_H37Rv TYSCAYFEPPELTLEEAQYAKVDLNLDKLDLKPGMTLLDIGCGWGTTMRR
MMAR_0977|M.marinum_M IYSCAYFEPPELTLEEAQYAKIDLNLDKLDLKPGMTLLDIGCGWGTTMKR
MUL_0729|M.ulcerans_Agy99 IYSCAYFEPPELTLEEAQYAKIDLNLDKLDLKPGMTLLDIGCGWGTTMKR
MAV_4517|M.avium_104 TYSCAYFARDDMSLEEAQYAKIDLNLDKLDLKPGMTLLDIGCGWGTTMKR
MLBr_01903|M.leprae_Br4923 TYSCAYFEPPDLTLEEAQYAKIDLNLNKLDLKPGMTLLDIGCGWGTTMRR
MAB_3881|M.abscessus_ATCC_1997 TYSCAYFEPETLTLEQAQQAKIDLALGKLNLEPGMTLLDVGCGWGSTMKR
MSMEG_0902|M.smegmatis_MC2_155 TYSCAYFAQDGMTLEEAQIAKIDLALGKLGLEPGMTLLDVGCGWGATMRR
***.** :*.:** *.:* *. *.*:******::***** *::*
Mflv_5113|M.gilvum_PYR-GCK AMEKYDVNVIGLTLSKNQKAYCDQLLGKLGSERTFDVRLEGWEQFHSPVD
Mvan_1239|M.vanbaalenii_PYR-1 AMEKYDVNVIGLTLSKNQKAYCDQLLSKLDTERTFDVRLEGWEQFHSPVD
TH_1862|M.thermoresistible__bu AIEKYDVNVIGLTLSRNQQAYCTQLLEQLDTNRSFDVRLMGWEQFHDPVD
Mb0661c|M.bovis_AF2122/97 AVERLDVNVIGLTLSKNQHARCEQVLASIDTNRSRQVLLQGWEDFAEPVD
Rv0642c|M.tuberculosis_H37Rv AVERFDVNVIGLTLSKNQHARCEQVLASIDTNRSRQVLLQGWEDFAEPVD
MMAR_0977|M.marinum_M AVERFDVNVIGLTLSKNQHARCESVLGEIDTNRSRQVRLHGWEDFNEPVD
MUL_0729|M.ulcerans_Agy99 AVERFDVNVIGLTLSKNQHARCESVLGEIDTNRSRQVRLHGWEDSNEPVD
MAV_4517|M.avium_104 AVERFDVNVIGLTLSKNQHARCEELLASLDSNRCRQVRLQNWEDFNEPVD
MLBr_01903|M.leprae_Br4923 AVEKYDVKVIGLTLSKNQHARCEQVLTALESNRSRQVRLQGWEDFTEPVD
MAB_3881|M.abscessus_ATCC_1997 ALEHYDVNVIGLTLSKNQFAYVNTLLDSAGSSRNYEVRLAGWEEFEGTVD
MSMEG_0902|M.smegmatis_MC2_155 AVERHDVNVVGLTLSRNQAAHVERMLDDVGSRRSRRVLLQGWEQFDEPVD
*:*: **:*:*****:** * :* : * * * .**: .**
Mflv_5113|M.gilvum_PYR-GCK RIVSIEAFEHFGFERYDDFFKMCFDVLPEDGRMTIQSSVGYHPYDLAERG
Mvan_1239|M.vanbaalenii_PYR-1 RIVSIEAFEHFGFERYDDFFKTCFDILPEDGRMTIQSSVGYHPYDLAERG
TH_1862|M.thermoresistible__bu RIVSIEAFEHFGFERYDHFFRNCYDIMPDDGRMTIQSSVGYHPDNLRARG
Mb0661c|M.bovis_AF2122/97 RIVSIEAFEHFGHENYDDFFKRCFNIMPADGRMTVQSSVSYHPYEMAARG
Rv0642c|M.tuberculosis_H37Rv RIVSIEAFEHFGHENYDDFFKRCFNIMPADGRMTVQSSVSYHPYEMAARG
MMAR_0977|M.marinum_M RIVSIEAFEHFGHENYDDFFKRCFDIMPEDGRMTVQSSVSYHPFEMAARG
MUL_0729|M.ulcerans_Agy99 RIVSIEAFEHFGHENYDDFFKRCFDIMPEDGRMTVQSSVSYHPFEMAARG
MAV_4517|M.avium_104 RIVSIEAFEHFGHENYDDFFKRTFDIMPDDGRMTVQSSVSYHPYDLAARG
MLBr_01903|M.leprae_Br4923 RIVSIEAFEHFGHENYDDFFKRCFNIMPSDGRMTVQSSVSYHPFDMAARG
MAB_3881|M.abscessus_ATCC_1997 RIVSIGAFEHFGHERYDSFFAMAHRVLPSDGKMLLHTIVSHHPDEWKRMG
MSMEG_0902|M.smegmatis_MC2_155 RIVSIGAFEHFRHERYDEFFAKAHALLPDDGVMLLHTICGFHPNHFREAG
***** ***** .*.** ** . ::* ** * ::: ..** . *
Mflv_5113|M.gilvum_PYR-GCK KKLTFELARFVKFMITEIFPGGRLPTTQMMVEHGEKAGFTVPQPLSLRNH
Mvan_1239|M.vanbaalenii_PYR-1 KKLTFELARFIKFMITEIFPGGRLPTTQMMIEHGEKAGFVVPDALSLRNH
TH_1862|M.thermoresistible__bu KKLTFELARFIKFMITEIFPGGRIPTTEMMVEHGEKAGFVVPETMSLRNH
Mb0661c|M.bovis_AF2122/97 KKLSFETARFIKFIVTEIFPGGRLPSTEMMVEHGEKAGFTVPEPLSLRPH
Rv0642c|M.tuberculosis_H37Rv KKLSFETARFIKFIVTEIFPGGRLPSTEMMVEHGEKAGFTVPEPLSLRPH
MMAR_0977|M.marinum_M KKLTFETARFIKFIVTEIFPGGRLPSTGMMVEHGEKAGFVVPEPLSLRPH
MUL_0729|M.ulcerans_Agy99 KKLTFETARFIKFIVTEIFPGGRLPSTGMMVEHGEKAGFVVPEPLSLRPY
MAV_4517|M.avium_104 KKLSFETARFIKFIVTEIFPGGRLPSTQMMVDHGEKAGFVVPEPLSLRPH
MLBr_01903|M.leprae_Br4923 KKLSFETARFIKFIITEIFPGGRLPSTKMMVEHGEKAGFTVSEPLSLQSH
MAB_3881|M.abscessus_ATCC_1997 IPLLMSRVRFIYFIGTEIFPGGRLPSVPMVDKHAALAGFHITRHHSLQPH
MSMEG_0902|M.smegmatis_MC2_155 IPMTMEMAKFVKFILTEIFPGGQLPSSEMVHDRAGRAGFVVSREQSLQPH
: :. .:*: *: *******::*: *: .:. *** :. **: :
Mflv_5113|M.gilvum_PYR-GCK YIKTLGIWADRLEANKDAAIAATDEENYERYMRYLKGCQYYFIDEAIDVS
Mvan_1239|M.vanbaalenii_PYR-1 YIKTLGIWADRLEQNKDAAIAATDEENYRRYMRYLKGCQYYFIDEAIDVS
TH_1862|M.thermoresistible__bu YIKTLGMWADALERNKERAIAITDEENYHRYMRYLRGCQYYFIDECIDVS
Mb0661c|M.bovis_AF2122/97 YIKTLRIWGDTLQSNKDKAIEVTSEEVYNRYMKYLRGCEHYFTDEMLDCS
Rv0642c|M.tuberculosis_H37Rv YIKTLRIWGDTLQSNKDKAIEVTSEEVYNRYMKYLRGCEHYFTDEMLDCS
MMAR_0977|M.marinum_M YIKTLRIWGDNLEANKEKAIEVTSEEVYNRYIKYLRGCEHYFTDEMLDCS
MUL_0729|M.ulcerans_Agy99 YIKTLRIWGDNLEANKEKAIEVTSEEVYNRYIKYLRGCEHYFTDEMLDCS
MAV_4517|M.avium_104 YIKTLHIWGDTLESNRDKAIEVTSEEVYNRYIKYLRGCEHYFTEEMLDCS
MLBr_01903|M.leprae_Br4923 YVKTLRIWGDTLESNRAKAIEVTSEAVYNRYMKYLRGCAHYFSDEMLDCS
MAB_3881|M.abscessus_ATCC_1997 YARTLDCWATNLAAHEDEAISVQSQEVYDRYIKYLTGCAEGFREGWIDVV
MSMEG_0902|M.smegmatis_MC2_155 YAKTLDIWASRLQAHQDEAIAIQSLEVYQRYMKYLTGCAQLFRDGQVDVV
* :** *. * :. ** . * **::** ** * : :*
Mflv_5113|M.gilvum_PYR-GCK LVTYLKPAVAA-
Mvan_1239|M.vanbaalenii_PYR-1 LVTYLKPGVAA-
TH_1862|M.thermoresistible__bu LVTYLKPGAVR-
Mb0661c|M.bovis_AF2122/97 LVTYLKPGAAA-
Rv0642c|M.tuberculosis_H37Rv LVTYLKPGAAA-
MMAR_0977|M.marinum_M LVTYLKPGAVSA
MUL_0729|M.ulcerans_Agy99 LVTYLKPGAVSA
MAV_4517|M.avium_104 LVTYLKPGAAA-
MLBr_01903|M.leprae_Br4923 LVTYLKPGALD-
MAB_3881|M.abscessus_ATCC_1997 QFTCEK------
MSMEG_0902|M.smegmatis_MC2_155 QFTLQKGR----
.* *