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GEPFIGSEALRAGRLTRHQLRTAHIAVYPDVYVPVATTLTAVAKAKAASLWTGREGIIAGQSAAAIHGAR WVDARRPAEVLWHNRRAPRGVLVWSDRVADDEVTTVRGVRVTTPERTALDIACRYPQRRAVAAIDALARA AHMKLADVELLVDRHTGRRGIRAARAALNLVDPGAESPQETYLRLTVIGNHFPPPQTQIPVWDCGALVAE LDMGWEHMMIGLDYEGDHHRTTREAFNKGIRRHDAVTELGWTDIRVTCNDTEGAIIARLTTAWRQRLCAL GENPDAGPPWTHVRRQRPGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4708 | - | - | 100% (301) | hypothetical protein Mflv_4708 |
| M. gilvum PYR-GCK | Mflv_4792 | - | 3e-60 | 43.68% (277) | hypothetical protein Mflv_4792 |
| M. gilvum PYR-GCK | Mflv_4733 | - | 8e-56 | 41.37% (278) | hypothetical protein Mflv_4733 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3546 | - | 3e-99 | 62.68% (276) | hypothetical protein Mb3546 |
| M. tuberculosis H37Rv | Rv3517 | - | 4e-99 | 62.68% (276) | hypothetical protein Rv3517 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1570 | - | 5e-78 | 50.54% (279) | hypothetical protein MAB_1570 |
| M. marinum M | MMAR_5026 | - | 1e-67 | 46.76% (278) | hypothetical protein MMAR_5026 |
| M. avium 104 | MAV_0642 | - | 1e-89 | 54.74% (285) | hypothetical protein MAV_0642 |
| M. smegmatis MC2 155 | MSMEG_5917 | - | 4e-86 | 57.30% (274) | hypothetical protein MSMEG_5917 |
| M. thermoresistible (build 8) | TH_1775 | - | 8e-83 | 53.48% (273) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2811 | - | 8e-62 | 44.80% (279) | hypothetical protein MUL_2811 |
| M. vanbaalenii PYR-1 | Mvan_1656 | - | 1e-65 | 46.49% (299) | hypothetical protein Mvan_1656 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1570|M.abscessus_ATCC_1997 ----MGEPFVGSEAVRSGRLTAYALRTRYVAIHPDVYLPRGAQLTPLVRA
MMAR_5026|M.marinum_M ----MAVPFLGSEAVASGEVRKSALRTRYHRLFPDVYIRCDAELSPQARA
Mflv_4708|M.gilvum_PYR-GCK ----MGEPFIGSEALRAGRLTRHQLRTAHIAVYPDVYVPVATTLTAVAKA
MSMEG_5917|M.smegmatis_MC2_155 ----MGDPVIGTEAVAAGFATPYQLRSRYWPVYPGIYVPKDTQPTAALRA
Mb3546|M.bovis_AF2122/97 ----MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRA
Rv3517|M.tuberculosis_H37Rv ----MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRA
MAV_0642|M.avium_104 ----MAEPFIGSEAVASGLVTPYALRSRFVRVHPDVYVPAGTALSAGLRA
TH_1775|M.thermoresistible__bu MAAPFSEPFLGSEALTSGALTRHQLRTRYRAIHRDVYIANDAELDAVLRA
MUL_2811|M.ulcerans_Agy99 -MCDLRAPFIGSKALACGAVTRHQLRTRYRPVLPNVYLSAGVHPCLQSRI
Mvan_1656|M.vanbaalenii_PYR-1 ----MGRVFIGSEALAAGALTRSALRWNYRRILPDVYVPAASQLSLRDRT
: .:*::*: .* ** . : .:*: :
MAB_1570|M.abscessus_ATCC_1997 QASWLWTGRRGILAGHSASALHGARWIDAARNAEIVHDNRHRQPGITVWS
MMAR_5026|M.marinum_M RAGWLWSRRRGIVAGLAASALHGARWVDPDAPLDILHVNRNPRPGIRARG
Mflv_4708|M.gilvum_PYR-GCK KAASLWTGREGIIAGQSAAAIHGARWVDARRPAEVLWHNRRAPRGVLVWS
MSMEG_5917|M.smegmatis_MC2_155 KAAWLWSDRRAVLAGRSASALHRSRWLDPRAPAELIHDNRRPPCGIKTWL
Mb3546|M.bovis_AF2122/97 QAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWS
Rv3517|M.tuberculosis_H37Rv QAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWS
MAV_0642|M.avium_104 RSAWLWSRRRGVVAGRSAAALYGTKWIDDRAPAQLLYPYRRPPDGIQTWS
TH_1775|M.thermoresistible__bu KACWLRSRGHGVLAGFSASALHGAKYVDPRRPATVIDTNRRRTPGILTWG
MUL_2811|M.ulcerans_Agy99 AAAWLWSRGSATVGGAAAAALHGAKWIPEDVPVELICARSSPPRGVLTRR
Mvan_1656|M.vanbaalenii_PYR-1 IAAWLWSGRGAVVAGAAAAALHGAKWVDAEVPIELIWRCGRPPPGVVVRN
: * : . :.* :*:*:: :::: :: *: .
MAB_1570|M.abscessus_ATCC_1997 GEIAPDEICVVRGMRATTAARTALDLACRCPRGRAVAAIDALCRATELQI
MMAR_5026|M.marinum_M DRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRAADVGR
Mflv_4708|M.gilvum_PYR-GCK DRVADDEVTTVRGVRVTTPERTALDIACRYPQRRAVAAIDALARAAHMKL
MSMEG_5917|M.smegmatis_MC2_155 DRFEDDEITVVDGIRVTTPARTAVDLACRYPLDTAVTLIDALGNATRLKM
Mb3546|M.bovis_AF2122/97 DRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKL
Rv3517|M.tuberculosis_H37Rv DRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKL
MAV_0642|M.avium_104 DRLVGDEIQTIGGMPVTTPARTALDIACRSPVDKAVAAIDALARATELKV
TH_1775|M.thermoresistible__bu HTLDEDEICEIDGMRLTTPARTAVDLACRYPVGTSVAAIDALARAARLKV
MUL_2811|M.ulcerans_Agy99 DVLIDGETQFLGGYSVTTAERTAFDIGRRGAMRSAVVRLDALARATGFTV
Mvan_1656|M.vanbaalenii_PYR-1 ERIDGDEVTGVAGMLVTTPERTAFDLARHLRRNPAVARLDALANATDVKA
. .* : * **. ***.*:. :*. :*:* .*: .
MAB_1570|M.abscessus_ATCC_1997 SEALELASRHAGMRGIRRARTAFELVDAGAQSPKETWLRLLLRDAGLPPV
MMAR_5026|M.marinum_M AQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRP
Mflv_4708|M.gilvum_PYR-GCK ADVELLVDRHTGRRGIRAARAALNLVDPGAESPQETYLRLTVIGNHFPPP
MSMEG_5917|M.smegmatis_MC2_155 ADVELLVDRYRGRRGIKNARHVLDLVDGGAESPRETWLRLEVIRGGFPRP
Mb3546|M.bovis_AF2122/97 ADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRP
Rv3517|M.tuberculosis_H37Rv ADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRP
MAV_0642|M.avium_104 LEIELLADRYRGRRGITRARNVLPLVDAGAESPRETWLRLLLLRAGFPRP
TH_1775|M.thermoresistible__bu ADIEAAAQRHPGRHGLRRAREAIALVDPGAESPRETALRLLIVRAGYPPP
MUL_2811|M.ulcerans_Agy99 ADVLQVARNHRGTRGLRQLETALELVDPGAQSPRESYLRLFLIDAGLPRP
Mvan_1656|M.vanbaalenii_PYR-1 VDVLTLAQRYPGARGMRRAVKSLSLMDGGAQSPRESRLRLLLVDTWLDPV
: .: : : . * **:**:*: *** :
MAB_1570|M.abscessus_ATCC_1997 STQILVHNGDFVALAYIDMGWEDVMVGIEYDGDQHRSDRRQYLKDIRRLE
MMAR_5026|M.marinum_M QTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQYSWDIRRKE
Mflv_4708|M.gilvum_PYR-GCK QTQIPVWD-CGALVAELDMGWEHMMIGLDYEGDHHRTTREAFNKGIRRHD
MSMEG_5917|M.smegmatis_MC2_155 QTQIPVHDEYGVLVGVFDMGWEDAMVGLDYEGDQHRTDRRRFNRDIHKSE
Mb3546|M.bovis_AF2122/97 QTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAE
Rv3517|M.tuberculosis_H37Rv QTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAE
MAV_0642|M.avium_104 RTQLPVR-QYGALIACLDMGWEDIKLAVEYDGDQHRTDRRQFTKDIRRAE
TH_1775|M.thermoresistible__bu ETQLPIHNEFGVLIGVVDMGWRDRRIAVEYEGRHHFTSRRAINRDIRRHD
MUL_2811|M.ulcerans_Agy99 QTQLPVLGVNGMPVAYLDMGWERYMVAVEYDGDHHRSDRQQYVKDIRRGE
Mvan_1656|M.vanbaalenii_PYR-1 RTQIKVG--EGRDVAYLDMGYDEPMIGLDYEGAHHNEDRKTYVYDIGRAE
**: : :. .***: :.::*:* :* *. .* : :
MAB_1570|M.abscessus_ATCC_1997 MLEGMGWLIVRVVAEDHPHDIIRRVREALARRV-----------------
MMAR_5026|M.marinum_M ILERLGWTVIRVLAGDRPTDILRRVRAALVRRASR---------------
Mflv_4708|M.gilvum_PYR-GCK AVTELGWTDIRVTCNDTEGAIIARLTTAWRQRLCALGENPDAGPPWTHVR
MSMEG_5917|M.smegmatis_MC2_155 DVRRLGWTHIRVTAQDGEADILKRIEAAGVPR----------GP---RV-
Mb3546|M.bovis_AF2122/97 ALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------------
Rv3517|M.tuberculosis_H37Rv ALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------------
MAV_0642|M.avium_104 VLAELGWTVVRVTAEDTPAGIIARVPTAWTRRACTGSEKPARNSR-----
TH_1775|M.thermoresistible__bu DMLEMGWTVLRVTAADTDGGFLRRLETAWSRPAEHSPAQHSPAQRSPAQR
MUL_2811|M.ulcerans_Agy99 MLERMGWIVIRVVAEDRRVDILRRVTAALAER-------------RSAVP
Mvan_1656|M.vanbaalenii_PYR-1 RIESRGWIDIKVVKEHSSEFIQARVTEAFARRGYTPRLRPLPRKRRRRRP
: ** ::* . : *: *
MAB_1570|M.abscessus_ATCC_1997 ------
MMAR_5026|M.marinum_M ------
Mflv_4708|M.gilvum_PYR-GCK RQRPGQ
MSMEG_5917|M.smegmatis_MC2_155 ------
Mb3546|M.bovis_AF2122/97 ------
Rv3517|M.tuberculosis_H37Rv ------
MAV_0642|M.avium_104 ------
TH_1775|M.thermoresistible__bu S-----
MUL_2811|M.ulcerans_Agy99 ------
Mvan_1656|M.vanbaalenii_PYR-1 ------