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RRPFVGSEALASGALTRSALRWNYRRIFPDVYLPVDVRPTLYDLTVAAWLWSGRRGVIAGAAASALHGSR WVVPTVPIEMIWQNGRPPPGIVVRNERIDGDETCVRGGMLVTTPERTAFDLARHLRRDQAVARLDALANA TEVKAVDVLALAERHPAARGIRRAVAALSLMDGGAQSPRETWLRLLLVDEWLDPLRTQVEVGDGRTTVHL DLGYDEPRIGLEYEGSHHSEDRRTYVHDIGRTEFIERHGWVAIKVVKEHSPEFIRFRVREAFARRGVTPR LRSGSRNRQRPRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4792 | - | - | 100% (294) | hypothetical protein Mflv_4792 |
| M. gilvum PYR-GCK | Mflv_4733 | - | 2e-69 | 48.72% (273) | hypothetical protein Mflv_4733 |
| M. gilvum PYR-GCK | Mflv_1289 | - | 5e-61 | 44.60% (278) | hypothetical protein Mflv_1289 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3546 | - | 3e-64 | 47.64% (275) | hypothetical protein Mb3546 |
| M. tuberculosis H37Rv | Rv3517 | - | 3e-64 | 47.64% (275) | hypothetical protein Rv3517 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1570 | - | 2e-69 | 50.00% (278) | hypothetical protein MAB_1570 |
| M. marinum M | MMAR_0375 | - | 2e-69 | 48.18% (274) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_4752 | - | 1e-75 | 53.38% (281) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_0850 | - | 7e-78 | 56.13% (269) | hypothetical protein MSMEG_0850 |
| M. thermoresistible (build 8) | TH_4125 | - | 9e-95 | 62.09% (277) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 3e-67 | 46.72% (274) | hypothetical protein MUL_4737 |
| M. vanbaalenii PYR-1 | Mvan_1656 | - | 1e-125 | 73.47% (294) | hypothetical protein Mvan_1656 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0375|M.marinum_M MDAREARAARSEDVFVGSEAVRRGRLSPYRLRTEFRAIYPDVYLPAHAAP
MUL_4737|M.ulcerans_Agy99 MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLPAHAAP
MAV_4752|M.avium_104 ---------MGEAPVVGSEELASGRLNRHRLRVAYRPVFPNVYLPAQVEP
Mb3546|M.bovis_AF2122/97 ----------MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADL
Rv3517|M.tuberculosis_H37Rv ----------MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADL
MAB_1570|M.abscessus_ATCC_1997 ----------MGEPFVGSEAVRSGRLTAYALRTRYVAIHPDVYLPRGAQL
Mflv_4792|M.gilvum_PYR-GCK ----------MRRPFVGSEALASGALTRSALRWNYRRIFPDVYLPVDVRP
Mvan_1656|M.vanbaalenii_PYR-1 ----------MGRVFIGSEALAAGALTRSALRWNYRRILPDVYVPAASQL
TH_4125|M.thermoresistible__bu ----------MREVFIGSAALRGGGLTRGRLRWNYRAMYPDVYVAKDRPP
MSMEG_0850|M.smegmatis_MC2_155 ----------MGEVVIGGEALAKGLVTRNDLRHHYRRLFPGVYVRGE--P
.:*. : * :. ** : : *.**:
MMAR_0375|M.marinum_M SFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWRNPHPPA
MUL_4737|M.ulcerans_Agy99 SFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRNPHPPA
MAV_4752|M.avium_104 TLPLRIRAAWLWSGRTAVIAGAAAAAVHGAAWIPDAVPIELIHHNTRAPD
Mb3546|M.bovis_AF2122/97 TAWSRAQAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPA
Rv3517|M.tuberculosis_H37Rv TAWSRAQAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPA
MAB_1570|M.abscessus_ATCC_1997 TPLVRAQASWLWTGRRGILAGHSASALHGARWIDAARNAEIVHDNRHRQP
Mflv_4792|M.gilvum_PYR-GCK TLYDLTVAAWLWSGRRGVIAGAAASALHGSRWVVPTVPIEMIWQNGRPPP
Mvan_1656|M.vanbaalenii_PYR-1 SLRDRTIAAWLWSGRGAVVAGAAAAALHGAKWVDAEVPIELIWRCGRPPP
TH_4125|M.thermoresistible__bu TLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWKAGRPPP
MSMEG_0850|M.smegmatis_MC2_155 TLRDRTVGAWLWSGRRGVLAGVAASALHGSAWVDPDVPIELIWRNGRPPA
: .:***: * .:: * :*:.:**: :: *:: :
MMAR_0375|M.marinum_M GVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDALMR
MUL_4737|M.ulcerans_Agy99 GVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDALMR
MAV_4752|M.avium_104 GVLIRRDGLCPGETQICDGLAVTTPERTAFDIGRRGAVRSAVVRLDSLAR
Mb3546|M.bovis_AF2122/97 GIHTWSDRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALAR
Rv3517|M.tuberculosis_H37Rv GIHTWSDRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALAR
MAB_1570|M.abscessus_ATCC_1997 GITVWSGEIAPDEICVVRGMRATTAARTALDLACRCPRGRAVAAIDALCR
Mflv_4792|M.gilvum_PYR-GCK GIVVRNERIDGDETCVRGGMLVTTPERTAFDLARHLRRDQAVARLDALAN
Mvan_1656|M.vanbaalenii_PYR-1 GVVVRNERIDGDEVTGVAGMLVTTPERTAFDLARHLRRNPAVARLDALAN
TH_4125|M.thermoresistible__bu RIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRHLDALAG
MSMEG_0850|M.smegmatis_MC2_155 GLIVRNETLAADEVMRVAGLPVTTPARTAFDLARHLPRDEAVARIDALAW
: : : .: .** ***:*:. : :* :*:*
MMAR_0375|M.marinum_M ATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWLRMVLID
MUL_4737|M.ulcerans_Agy99 ATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLRMVLID
MAV_4752|M.avium_104 ATGFKADDVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRESYLRLLLID
Mb3546|M.bovis_AF2122/97 ATDLKLADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIR
Rv3517|M.tuberculosis_H37Rv ATDLKLADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIR
MAB_1570|M.abscessus_ATCC_1997 ATELQISEALELASRHAGMRGIRRARTAFELVDAGAQSPKETWLRLLLRD
Mflv_4792|M.gilvum_PYR-GCK ATEVKAVDVLALAERHPAARGIRRAVAALSLMDGGAQSPRETWLRLLLVD
Mvan_1656|M.vanbaalenii_PYR-1 ATDVKAVDVLTLAQRYPGARGMRRAVKSLSLMDGGAQSPRESRLRLLLVD
TH_4125|M.thermoresistible__bu ATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRLRLILVD
MSMEG_0850|M.smegmatis_MC2_155 TRRVTVDDVAALIERYPAARGIRAARAVLRLVDAGADSPRETWLRLRLTD
: . :. : : *: : *:* ** **:*: **: *
MMAR_0375|M.marinum_M AGLPVPVTQIPVH-QNWRLVAVLDMGWQKYQVAAEYDGDQHRFDRRQYAR
MUL_4737|M.ulcerans_Agy99 AGLPVPVTQIPVH-QNWRLVAVLDMGWQKYQVAAEYDGDQHRFDRRQYAR
MAV_4752|M.avium_104 AGLPRPQTQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHRTDRRQYVK
Mb3546|M.bovis_AF2122/97 AGFPRPQTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNK
Rv3517|M.tuberculosis_H37Rv AGFPRPQTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNK
MAB_1570|M.abscessus_ATCC_1997 AGLPPVSTQILVHNGDFVALAYIDMGWEDVMVGIEYDGDQHRSDRRQYLK
Mflv_4792|M.gilvum_PYR-GCK EWLDPLRTQVEVGD--GRTTVHLDLGYDEPRIGLEYEGSHHSEDRRTYVH
Mvan_1656|M.vanbaalenii_PYR-1 TWLDPVRTQIKVGE--GRDVAYLDMGYDEPMIGLDYEGAHHNEDRKTYVY
TH_4125|M.thermoresistible__bu DGLPRPRTQIGVSD--GVNEAFIDMGWDEPMVGLDYEGAHHSADRRQYVH
MSMEG_0850|M.smegmatis_MC2_155 AGLPPDSTQIPVVDERGRIVAILDMGWERHLVAVNYDGVFHQSDRKRYVR
: **: * . :*:*: :. :*:* * **: :
MMAR_0375|M.marinum_M DQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET-------
MUL_4737|M.ulcerans_Agy99 EQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET-------
MAV_4752|M.avium_104 DIRRLEMLEQLGWVIVRVVAEDRPADIVRRVRAALAKSGVAPRLSV----
Mb3546|M.bovis_AF2122/97 DIKRAEALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------
Rv3517|M.tuberculosis_H37Rv DIKRAEALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------
MAB_1570|M.abscessus_ATCC_1997 DIRRLEMLEGMGWLIVRVVAEDHPHDIIRRVREALARRV-----------
Mflv_4792|M.gilvum_PYR-GCK DIGRTEFIERHGWVAIKVVKEHSPEFIRFRVREAFARRGVTPRLRSGSRN
Mvan_1656|M.vanbaalenii_PYR-1 DIGRAERIESRGWIDIKVVKEHSSEFIQARVTEAFARRGYTPRLRPLPRK
TH_4125|M.thermoresistible__bu DIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRG-----------
MSMEG_0850|M.smegmatis_MC2_155 DLKTLRALEDRGWIVIRVVAEDDIADVITRVAAAP---------------
: . : ** ::* . : *. *
MMAR_0375|M.marinum_M -------
MUL_4737|M.ulcerans_Agy99 -------
MAV_4752|M.avium_104 -------
Mb3546|M.bovis_AF2122/97 -------
Rv3517|M.tuberculosis_H37Rv -------
MAB_1570|M.abscessus_ATCC_1997 -------
Mflv_4792|M.gilvum_PYR-GCK RQRPRP-
Mvan_1656|M.vanbaalenii_PYR-1 RRRRRP-
TH_4125|M.thermoresistible__bu WHLPKPV
MSMEG_0850|M.smegmatis_MC2_155 WLAPRLH