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GTILIGTEAVAEGLVTPGQLRYGYRRLFPDVYVPKAQPQSLADDAIGAWLWSGRRGIVTVRAAASLHGAR WVNSETPVELIYDCRRRPNGIIARNERIDWDEIVDNGQLSLATVERTAVDLGRHLPLGRAVAHLDALANA TGLTAESVYPLVDRYSGARGMKTLRKALDLMDGGAESPKETWLRLLLMREFPRPQTQIPLVDEWGMPLIR LDMGWEAAKIAVEYDGAHHQENRSQYVTDERRLRLIQARDWLYVKVIKEDKPAEILARVRRAWALRETAT TVAKRAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4733 | - | - | 100% (288) | hypothetical protein Mflv_4733 |
| M. gilvum PYR-GCK | Mflv_4792 | - | 2e-69 | 48.72% (273) | hypothetical protein Mflv_4792 |
| M. gilvum PYR-GCK | Mflv_4812 | - | 3e-69 | 47.84% (278) | hypothetical protein Mflv_4812 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1102 | - | 7e-67 | 47.04% (270) | hypothetical protein Mb1102 |
| M. tuberculosis H37Rv | Rv1073 | - | 7e-67 | 47.04% (270) | hypothetical protein Rv1073 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 1e-58 | 43.80% (274) | hypothetical protein MAB_2184 |
| M. marinum M | MMAR_0375 | - | 1e-66 | 45.45% (275) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_0642 | - | 2e-67 | 48.20% (278) | hypothetical protein MAV_0642 |
| M. smegmatis MC2 155 | MSMEG_0785 | - | 1e-73 | 47.18% (284) | hypothetical protein MSMEG_0785 |
| M. thermoresistible (build 8) | TH_4125 | - | 4e-71 | 49.28% (278) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 7e-65 | 44.36% (275) | hypothetical protein MUL_4737 |
| M. vanbaalenii PYR-1 | Mvan_1730 | - | 1e-116 | 67.71% (288) | hypothetical protein Mvan_1730 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4733|M.gilvum_PYR-GCK MGT----------ILIGTEAVAEGLVTPGQLRYGYRRLFPDVYVPKAQPQ
Mvan_1730|M.vanbaalenii_PYR-1 MGG----------VILGSEAIADGLVTSGRLRFGYSRLYPNVYVPRGQPQ
TH_4125|M.thermoresistible__bu MRE----------VFIGSAALRGGGLTRGRLRWNYRAMYPDVYVAKDRPP
MAV_0642|M.avium_104 MAE----------PFIGSEAVASGLVTPYALRSRFVRVHPDVYVPAGTAL
MSMEG_0785|M.smegmatis_MC2_155 MTA----------PFLGSEALADGTLNRHQLRTRFRTLYPNVYVPKTSEP
Mb1102|M.bovis_AF2122/97 MGAQP---------FIGSEALAAGLISWHELGKYYTAIMPNVYLDKRLKP
Rv1073|M.tuberculosis_H37Rv MGAQP---------FIGSEALAAGLISWHELGKYYTAIMPNVYLDKRLKP
MMAR_0375|M.marinum_M MDAREARAARSEDVFVGSEAVRRGRLSPYRLRTEFRAIYPDVYLPAHAAP
MUL_4737|M.ulcerans_Agy99 MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLPAHAAP
MAB_2184|M.abscessus_ATCC_1997 MAA----------VFVGSEAVSAGQLTRHELQRFYRPIFRGVYLPKSAEP
* ::*: *: * :. * : : .**:
Mflv_4733|M.gilvum_PYR-GCK SLADDAIGAWLWSGRRGIVTVRAAASLHGARWVNSETPVELIYDCRRRPN
Mvan_1730|M.vanbaalenii_PYR-1 SLIDNTVGAWLWSGRRAIVTGRAAAALHGARWVSEKARVELNYNCRRPPK
TH_4125|M.thermoresistible__bu TLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWKAGRPPP
MAV_0642|M.avium_104 SAGLRARSAWLWSRRRGVVAGRSAAALYGTKWIDDRAPAQLLYPYRRPPD
MSMEG_0785|M.smegmatis_MC2_155 TLEQRTVGAWLWSGRRAVIAGPAAAALHGAKWIDPSIPIDLIHDNPRQPR
Mb1102|M.bovis_AF2122/97 SLRQRVIAAWLWSGRKGVIAGASASALHGAKWVDDHALVELIWRNARAPN
Rv1073|M.tuberculosis_H37Rv SLRQRVIAAWLWSGRKGVIAGASASALHGAKWVDDHALVELIWRNARAPN
MMAR_0375|M.marinum_M SFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWRNPHPPA
MUL_4737|M.ulcerans_Agy99 SFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRNPHPPA
MAB_2184|M.abscessus_ATCC_1997 TLRDRTVAAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGVKCRQQE
: .*** : *..:: :*: *:*: ::. :* :
Mflv_4733|M.gilvum_PYR-GCK GIIARNERIDWDEIVDNGQLSLATVERTAVDLGRHLPLGRAVAHLDALAN
Mvan_1730|M.vanbaalenii_PYR-1 GIVCRDERIGCDEVIQVGELAVAAAHRTAFDLGRHLPLNSAVVHLDALAN
TH_4125|M.thermoresistible__bu RIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRHLDALAG
MAV_0642|M.avium_104 GIQTWSDRLVGDEIQTIGGMPVTTPARTALDIACRSPVDKAVAAIDALAR
MSMEG_0785|M.smegmatis_MC2_155 GITTRRDTLLPGETVVIGGMLLTSSARTAFDIGRRSPTNRGVAHLDALLR
Mb1102|M.bovis_AF2122/97 GVRTKDELLLDGEVQRLCGLTVTTVERTAFDLGRRPPLGQAITRLDALAN
Rv1073|M.tuberculosis_H37Rv GVRTKDELLLDGEVQRLCGLTVTTVERTAFDLGRRPPLGQAITRLDALAN
MMAR_0375|M.marinum_M GVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDALMR
MUL_4737|M.ulcerans_Agy99 GVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDALMR
MAB_2184|M.abscessus_ATCC_1997 GLIARNERIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGCLDALMR
: : : : : :: ***.*:. * .: :***
Mflv_4733|M.gilvum_PYR-GCK ATGLTAESVYPLVDRYSGARGMKTLRKALDLMDGGAESPKETWLRLLLMR
Mvan_1730|M.vanbaalenii_PYR-1 ATGLTRERVLPLLDEYRGARGMKKLRTALDLMDGGAQSPRETWLRLLLMK
TH_4125|M.thermoresistible__bu ATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRLRLILVD
MAV_0642|M.avium_104 ATELKVLEIELLADRYRGRRGITRARNVLPLVDAGAESPRETWLRLLLLR
MSMEG_0785|M.smegmatis_MC2_155 ATGCTVADIADLANRHRGARGLRRLEATLPLVDAGAQSPKETWLRLLIVR
Mb1102|M.bovis_AF2122/97 ATDFKINDVRELARKHPHTRGLRQLDKALDLVDPGAQSPKETWLRLLLIN
Rv1073|M.tuberculosis_H37Rv ATDFKINDVRELARKHPHTRGLRQLDKALDLVDPGAQSPKETWLRLLLIN
MMAR_0375|M.marinum_M ATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWLRMVLID
MUL_4737|M.ulcerans_Agy99 ATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLRMVLID
MAB_2184|M.abscessus_ATCC_1997 NQVFALDEVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLIRLQLRD
: * .: **: * *:* ** **:*: :*: :
Mflv_4733|M.gilvum_PYR-GCK E-FPRPQTQIPLVDEWGMPLIRLDMGWEAAKIAVEYDGAHHQENRSQYVT
Mvan_1730|M.vanbaalenii_PYR-1 D-FPRPTTQIPLFNSRGAPFAYLDMGWEDLKIAVEYDGEHHQKNRDQYIW
TH_4125|M.thermoresistible__bu DGLPRPRTQIGVSD--GVNEAFIDMGWDEPMVGLDYEGAHHSADRRQYVH
MAV_0642|M.avium_104 AGFPRPRTQLPVR-QYGALIACLDMGWEDIKLAVEYDGDQHRTDRRQFTK
MSMEG_0785|M.smegmatis_MC2_155 DGLPKPTTQIPVLADDGTPLAYLDMGWEEWMVAVEYDGDQHRTDRRQYVR
Mb1102|M.bovis_AF2122/97 AGFPRPSTQIPLLGVYGHPKYFLDMGWEDIMLAVEYDGEQHRLSRDQFVK
Rv1073|M.tuberculosis_H37Rv AGFPRPSTQIPLLGVYGHPKYFLDMGWEDIMLAVEYDGEQHRLSRDQFVK
MMAR_0375|M.marinum_M AGLPVPVTQIPVHQNW-RLVAVLDMGWQKYQVAAEYDGDQHRFDRRQYAR
MUL_4737|M.ulcerans_Agy99 AGLPVPVTQIPVHQNW-RLVAVLDMGWQKYQVAAEYDGDQHRFDRRQYAR
MAB_2184|M.abscessus_ATCC_1997 AGLPRAQTQVPVFDGY-TPIAFLDIGWPQYLVAVEYDGDHHRRDRRQYVK
:* . **: : :*:** :. :*:* :* .* *:
Mflv_4733|M.gilvum_PYR-GCK DERRLRLIQARDWLYVKVIKEDKPAEILARVRRAWALRETA--TTVAKRA
Mvan_1730|M.vanbaalenii_PYR-1 DEQRLRLIRARDWLHIKVIKEDEPDDVTARVKRAWALRERA--FAVAERV
TH_4125|M.thermoresistible__bu DIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRG----WHLPKPV
MAV_0642|M.avium_104 DIRRAEVLAELGWTVVRVTAEDTPAGIIARVPTAWTRRACTGSEKPARNS
MSMEG_0785|M.smegmatis_MC2_155 DIRRLELLAELGWIVIRVVAEDGTAEILRRIRAALTARQST--VRSGRKA
Mb1102|M.bovis_AF2122/97 DVERLEYIRRAGWTHIRVLADHKGPDVVRRVRQAWDTLT--------SRR
Rv1073|M.tuberculosis_H37Rv DVERLEYIRRAGWTHIRVLADHKGPDVVRRVRQAWDTLT--------SRR
MMAR_0375|M.marinum_M DQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRG--------HRE
MUL_4737|M.ulcerans_Agy99 EQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRG--------HRE
MAB_2184|M.abscessus_ATCC_1997 DLARLRMLEERGWTVIRVIAEESPGAWIARTTAALRSRGCHIEIDEMQRS
: * . : .* ::* . * *
Mflv_4733|M.gilvum_PYR-GCK S-----
Mvan_1730|M.vanbaalenii_PYR-1 S-----
TH_4125|M.thermoresistible__bu ------
MAV_0642|M.avium_104 R-----
MSMEG_0785|M.smegmatis_MC2_155 S-----
Mb1102|M.bovis_AF2122/97 ------
Rv1073|M.tuberculosis_H37Rv ------
MMAR_0375|M.marinum_M T-----
MUL_4737|M.ulcerans_Agy99 T-----
MAB_2184|M.abscessus_ATCC_1997 TRPFAA