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AVPFLGSEAVASGEVRKSALRTRYHRLFPDVYIRCDAELSPQARARAGWLWSRRRGIVAGLAASALHGAR WVDPDAPLDILHVNRNPRPGIRARGDRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRA ADVGRAQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRPQTQIRVADEWGELVA YLDMGWEELMVAVEYDGEQHRNDRRQYSWDIRRKEILERLGWTVIRVLAGDRPTDILRRVRAALVRRASR *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5026 | - | - | 100% (281) | hypothetical protein MMAR_5026 |
| M. marinum M | MMAR_0375 | - | 2e-74 | 50.18% (277) | hypothetical protein MMAR_0375 |
| M. marinum M | MMAR_0712 | - | 3e-70 | 48.57% (280) | hypothetical protein MMAR_0712 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3546 | - | 2e-81 | 53.45% (275) | hypothetical protein Mb3546 |
| M. gilvum PYR-GCK | Mflv_4708 | - | 8e-68 | 46.76% (278) | hypothetical protein Mflv_4708 |
| M. tuberculosis H37Rv | Rv3517 | - | 2e-81 | 53.45% (275) | hypothetical protein Rv3517 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1570 | - | 8e-83 | 56.12% (278) | hypothetical protein MAB_1570 |
| M. avium 104 | MAV_3351 | - | 1e-109 | 67.63% (278) | hypothetical protein MAV_3351 |
| M. smegmatis MC2 155 | MSMEG_0785 | - | 2e-78 | 52.14% (280) | hypothetical protein MSMEG_0785 |
| M. thermoresistible (build 8) | TH_1775 | - | 2e-72 | 49.28% (276) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4100 | - | 1e-137 | 98.73% (237) | hypothetical protein MUL_4100 |
| M. vanbaalenii PYR-1 | Mvan_1656 | - | 3e-62 | 45.62% (274) | hypothetical protein Mvan_1656 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5026|M.marinum_M ----MAVPFLGSEAVASGEVRKSALRTRYHRLFPDVYIRCDAELSPQARA
MUL_4100|M.ulcerans_Agy99 ----MAVPFLGSEAVAGGEVRKSALRTRYHRLFPDVYIRCDAELSPQARA
MAV_3351|M.avium_104 ----MVEPFIGSEAVADGEVVKSALRTRYKRLFRDVYIHPGAELSALTRA
MAB_1570|M.abscessus_ATCC_1997 ----MGEPFVGSEAVRSGRLTAYALRTRYVAIHPDVYLPRGAQLTPLVRA
Mb3546|M.bovis_AF2122/97 ----MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRA
Rv3517|M.tuberculosis_H37Rv ----MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRA
Mflv_4708|M.gilvum_PYR-GCK ----MGEPFIGSEALRAGRLTRHQLRTAHIAVYPDVYVPVATTLTAVAKA
TH_1775|M.thermoresistible__bu MAAPFSEPFLGSEALTSGALTRHQLRTRYRAIHRDVYIANDAELDAVLRA
MSMEG_0785|M.smegmatis_MC2_155 ----MTAPFLGSEALADGTLNRHQLRTRFRTLYPNVYVPKTSEPTLEQRT
Mvan_1656|M.vanbaalenii_PYR-1 ----MGRVFIGSEALAAGALTRSALRWNYRRILPDVYVPAASQLSLRDRT
: *:****: * : ** . : :**: : ::
MMAR_5026|M.marinum_M RAGWLWSRRRGIVAGLAASALHGARWVDPDAPLDILHVNRNPRPGIRARG
MUL_4100|M.ulcerans_Agy99 RAGWLWSRRRGIVTGLSASALHGARWVDPDAPLDILHVNRNPRPGIRARG
MAV_3351|M.avium_104 RAGWLWSRRRGVIAGLSAAAVHGARWVDATAPLEILHSNRNPLPGLRIHS
MAB_1570|M.abscessus_ATCC_1997 QASWLWTGRRGILAGHSASALHGARWIDAARNAEIVHDNRHRQPGITVWS
Mb3546|M.bovis_AF2122/97 QAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWS
Rv3517|M.tuberculosis_H37Rv QAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWS
Mflv_4708|M.gilvum_PYR-GCK KAASLWTGREGIIAGQSAAAIHGARWVDARRPAEVLWHNRRAPRGVLVWS
TH_1775|M.thermoresistible__bu KACWLRSRGHGVLAGFSASALHGAKYVDPRRPATVIDTNRRRTPGILTWG
MSMEG_0785|M.smegmatis_MC2_155 VGAWLWSGRRAVIAGPAAAALHGAKWIDPSIPIDLIHDNPRQPRGITTRR
Mvan_1656|M.vanbaalenii_PYR-1 IAAWLWSGRGAVVAGAAAAALHGAKWVDAEVPIELIWRCGRPPPGVVVRN
. * : .:::* :*:*:***:::*. :: . *:
MMAR_5026|M.marinum_M DRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRAADVGR
MUL_4100|M.ulcerans_Agy99 DRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRAADVGR
MAV_3351|M.avium_104 DRLESDEYALVDGVPVTTPARTAVDLGCWHPVNDAVAVIDDLLRATDCKV
MAB_1570|M.abscessus_ATCC_1997 GEIAPDEICVVRGMRATTAARTALDLACRCPRGRAVAAIDALCRATELQI
Mb3546|M.bovis_AF2122/97 DRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKL
Rv3517|M.tuberculosis_H37Rv DRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKL
Mflv_4708|M.gilvum_PYR-GCK DRVADDEVTTVRGVRVTTPERTALDIACRYPQRRAVAAIDALARAAHMKL
TH_1775|M.thermoresistible__bu HTLDEDEICEIDGMRLTTPARTAVDLACRYPVGTSVAAIDALARAARLKV
MSMEG_0785|M.smegmatis_MC2_155 DTLLPGETVVIGGMLLTSSARTAFDIGRRSPTNRGVAHLDALLRATGCTV
Mvan_1656|M.vanbaalenii_PYR-1 ERIDGDEVTGVAGMLVTTPERTAFDLARHLRRNPAVARLDALANATDVKA
: .* : *: *:. ***.*:. .** :* * .*:
MMAR_5026|M.marinum_M AQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRP
MUL_4100|M.ulcerans_Agy99 AQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRP
MAV_3351|M.avium_104 AECQLLADRYPGRRGMQSARAAIGLADAGAQSPKETWLRLLLIRAGLPRP
MAB_1570|M.abscessus_ATCC_1997 SEALELASRHAGMRGIRRARTAFELVDAGAQSPKETWLRLLLRDAGLPPV
Mb3546|M.bovis_AF2122/97 ADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRP
Rv3517|M.tuberculosis_H37Rv ADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRP
Mflv_4708|M.gilvum_PYR-GCK ADVELLVDRHTGRRGIRAARAALNLVDPGAESPQETYLRLTVIGNHFPPP
TH_1775|M.thermoresistible__bu ADIEAAAQRHPGRHGLRRAREAIALVDPGAESPRETALRLLIVRAGYPPP
MSMEG_0785|M.smegmatis_MC2_155 ADIADLANRHRGARGLRRLEATLPLVDAGAQSPKETWLRLLIVRDGLPKP
Mvan_1656|M.vanbaalenii_PYR-1 VDVLTLAQRYPGARGMRRAVKSLSLMDGGAQSPRESRLRLLLVDTWLDPV
: *: : :: :. * **:**:*: *** :
MMAR_5026|M.marinum_M QTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQYSWDIRRKE
MUL_4100|M.ulcerans_Agy99 QTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQ---------
MAV_3351|M.avium_104 QTQIPVSDEFGGVTYYLDMGWEDFMVAAEYDGEQHRRDRWQYTWDIRRRE
MAB_1570|M.abscessus_ATCC_1997 STQILVHNGDFVALAYIDMGWEDVMVGIEYDGDQHRSDRRQYLKDIRRLE
Mb3546|M.bovis_AF2122/97 QTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAE
Rv3517|M.tuberculosis_H37Rv QTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAE
Mflv_4708|M.gilvum_PYR-GCK QTQIPVWD-CGALVAELDMGWEHMMIGLDYEGDHHRTTREAFNKGIRRHD
TH_1775|M.thermoresistible__bu ETQLPIHNEFGVLIGVVDMGWRDRRIAVEYEGRHHFTSRRAINRDIRRHD
MSMEG_0785|M.smegmatis_MC2_155 TTQIPVLADDGTPLAYLDMGWEEWMVAVEYDGDQHRTDRRQYVRDIRRLE
Mvan_1656|M.vanbaalenii_PYR-1 RTQIKVGE--GRDVAYLDMGYDEPMIGLDYEGAHHNEDRKTYVYDIGRAE
**: : :***: :. :*:* :* *
MMAR_5026|M.marinum_M ILERLGWTVIRVLAGDRPTDILRRVRAALVRRASR---------------
MUL_4100|M.ulcerans_Agy99 --------------------------------------------------
MAV_3351|M.avium_104 TLERLGWIVIQVVAGDRPADIVSRVSAALARRGVTLA-------------
MAB_1570|M.abscessus_ATCC_1997 MLEGMGWLIVRVVAEDHPHDIIRRVREALARRV-----------------
Mb3546|M.bovis_AF2122/97 ALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------------
Rv3517|M.tuberculosis_H37Rv ALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------------
Mflv_4708|M.gilvum_PYR-GCK AVTELGWTDIRVTCNDTEGAIIARLTTAWRQRLCALGENPDAGPPWTHVR
TH_1775|M.thermoresistible__bu DMLEMGWTVLRVTAADTDGGFLRRLETAWSRPA---EHSPAQHSPAQRSP
MSMEG_0785|M.smegmatis_MC2_155 LLAELGWIVIRVVAEDGTAEILRRIRAALTARQSTVRSGRKAS-------
Mvan_1656|M.vanbaalenii_PYR-1 RIESRGWIDIKVVKEHSSEFIQARVTEAFARRGYTPRLRPLPRKRRRRRP
MMAR_5026|M.marinum_M ------
MUL_4100|M.ulcerans_Agy99 ------
MAV_3351|M.avium_104 ------
MAB_1570|M.abscessus_ATCC_1997 ------
Mb3546|M.bovis_AF2122/97 ------
Rv3517|M.tuberculosis_H37Rv ------
Mflv_4708|M.gilvum_PYR-GCK RQRPGQ
TH_1775|M.thermoresistible__bu AQRS--
MSMEG_0785|M.smegmatis_MC2_155 ------
Mvan_1656|M.vanbaalenii_PYR-1 ------