For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPFILSSRTLFGPQSGEQRARQPLLQQLSATAPAVDQAIQSGPGLRPLANQAQNAITQLDPLVGALNTSP WCATTPQCAQIRDQVKILVTLRDSGFFTQIADLGDRYDPATNATVGGTLANVQNAVASLDKAFGALGDPA DLATNLRRLQDGIGQLASGAQALATGVRTLADSNIEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANA FENRQFTDVAEQFLSPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSVAGFPAVN SDIQRFLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTVVLNYLASLGIGVVVFQWGLGHEIAWPV PLLAFIILVAVGADYNMLLVSRLREESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQ AGLIIGFGLLLDTFLVRTLTVPAIATLLREASWWPTKATNPRRGDPKQKA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4635 | - | - | 100% (470) | MMPL domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0403 | - | 7e-95 | 41.53% (443) | transport protein |
| M. gilvum PYR-GCK | Mflv_2705 | - | 9e-55 | 31.45% (461) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1549c | mmpL12 | 4e-95 | 42.95% (454) | transmembrane transport protein MmpL12 |
| M. tuberculosis H37Rv | Rv1522c | mmpL12 | 2e-95 | 43.17% (454) | transmembrane transport protein MmpL12 |
| M. leprae Br4923 | MLBr_01231 | mmpL10 | 5e-88 | 39.41% (439) | hypothetical protein MLBr_01231 |
| M. abscessus ATCC 19977 | MAB_0937c | - | 1e-92 | 40.72% (447) | MmpL family protein |
| M. marinum M | MMAR_4836 | - | 0.0 | 79.28% (444) | MmpL family transport protein |
| M. avium 104 | MAV_1761 | - | 2e-89 | 40.79% (456) | MmpL10 protein |
| M. smegmatis MC2 155 | MSMEG_4741 | - | 1e-92 | 43.56% (404) | MmpL protein |
| M. thermoresistible (build 8) | TH_3450 | - | 0.0 | 82.53% (458) | PUTATIVE MMPL domain protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-52 | 36.73% (343) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_0312 | - | 0.0 | 99.11% (449) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 -MTDGTADSPSQATRSGRGANGSPDPADTREYSERLAALARFTLRHKALV
TH_3450|M.thermoresistible__bu -----------------------------------------------VLV
MMAR_4836|M.marinum_M MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIRHKVLI
Mb1549c|M.bovis_AF2122/97 -----------------------MARHDEAKAGGLFDRIGNFVVRWPLIV
Rv1522c|M.tuberculosis_H37Rv -----------------------MARHDEAKAGGLFDRIGNFVVRWPLIV
MSMEG_4741|M.smegmatis_MC2_155 ----------------------------MSRVG--FSGLGRFIVRHPLVV
MAB_0937c|M.abscessus_ATCC_199 -----------------------------------MRRLADLVVRWPWVV
MAV_1761|M.avium_104 -----------------------MSPTAPAGDEVEMRRIADFVVRWPWLV
MLBr_01231|M.leprae_Br4923 ------------------------------------------------MV
MUL_0757|M.ulcerans_Agy99 ---------------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPL
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 IGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGEE
TH_3450|M.thermoresistible__bu IGTWLAVAVVLALLFPQLETVVRQQSVDLIPRDVPSFQTLDRMSAAFGEQ
MMAR_4836|M.marinum_M IGMWVVTAAALAVLFPQLETVVRQQSVNLIPRDAPSLQTVDRMGAAFGEQ
Mb1549c|M.bovis_AF2122/97 IGCWIAVAAALTLLLPTLQAQAAKREQAPLPPGAPSMVLQKEMSAAFQEK
Rv1522c|M.tuberculosis_H37Rv IGCWIAVAAALTLLLPTLQAQAAKREQAPLPPGAPSMVLQKEMSAAFQEK
MSMEG_4741|M.smegmatis_MC2_155 IASWLAVAGVLLAAVPSLPAVAERNPPGFLPADSEVFAAGNAMQEAFNET
MAB_0937c|M.abscessus_ATCC_199 IGAWVALAIALPLTFPSLTEMAEKHPLAILPADAPSSVTAKKMTEAFHES
MAV_1761|M.avium_104 IGFWAALAVALPLAFPSLAEMAQKHPLAILPGNAPSNVAARQMTEAFHES
MLBr_01231|M.leprae_Br4923 IGCWTLLALMLPMTVPSLTELTQRHPVVILPVDAPSSVAAKKISQAFHEV
MUL_0757|M.ulcerans_Agy99 ILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREG
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 GS-KTMVFVAMEDPNGLTPTARQRYGELVSRLQSEGDHVLLVQDLLADPI
TH_3450|M.thermoresistible__bu GS-KTTVFVAMEDPAGLTPAARDRYEAMVSRLRADTDHVLLVQDLLADPV
MMAR_4836|M.marinum_M GS-KTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRLVQDLLADPV
Mb1549c|M.bovis_AF2122/97 IETSALLLVLLTNENGLGPADEAVYRKLIENLRADTQDKISVQDFLAVPE
Rv1522c|M.tuberculosis_H37Rv IETSALLLVLLTNENGLGPADEAVYRKLIENLRADTQDKISVQDFLAVPE
MSMEG_4741|M.smegmatis_MC2_155 GG-GNVAIAILSNENGLTPADEETYRALVDKLRADTEYVLSTQDFVTIPE
MAB_0937c|M.abscessus_ATCC_199 SN-DDLLLVVFINENGLGKDDADSYRKVVDALRHDLTNVVSVQDFIGTPE
MAV_1761|M.avium_104 GS-DDLLLVALTDEKGLGPADEAVYRRLVDALRRDTRDVVMVQDFISAPP
MLBr_01231|M.leprae_Br4923 DS-ENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTPP
MUL_0757|M.ulcerans_Agy99 DS-DSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPL
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 TEAQAVSVDRKAWYLPVGVAGTLGDPTAAESVNAVRDIAAEVFTG-----
TH_3450|M.thermoresistible__bu TATQAVSQDGKAWYLPVGVAGTLGDPTAAESVQAVRALAAEAFAD-----
MMAR_4836|M.marinum_M TASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQAFSG-----
Mb1549c|M.bovis_AF2122/97 MKELLASKDNKAWNLPITFAGDAASPETQAAFKRVAAIVKQTVAG-----
Rv1522c|M.tuberculosis_H37Rv MKELLASKDNKAWNLPITFAGDAASPETQAAFKRVAAIVKQTVAG-----
MSMEG_4741|M.smegmatis_MC2_155 LRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQIVDTVKSSTAN-----
MAB_0937c|M.abscessus_ATCC_199 LRKFLTSQDNKTWVLPVGLAGELGTPKAFESYNRVTSLIQHSID------
MAV_1761|M.avium_104 LRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRIAGIVKQTLEKHENGP
MLBr_01231|M.leprae_Br4923 LHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQTLES----T
MUL_0757|M.ulcerans_Agy99 TATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQAP-----
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 --STTTVHVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSVF
TH_3450|M.thermoresistible__bu --SSTTVRVTGPPATFSDQIGSAEHDLVLISIATAGLIALILLIVYRSVF
MMAR_4836|M.marinum_M --SPTNVRVTGPPATFHDQIASAEEDLVVISIATAGLIAMILLVVYRSVF
Mb1549c|M.bovis_AF2122/97 --TSLTVHLSGPIATVADLTELGEKDVRIIEIGAAVSVLIILILVYRNLV
Rv1522c|M.tuberculosis_H37Rv --TSLTVHLSGPIATVADLTELGEKDVRIIEIGTAVSVLIILILVYRNLV
MSMEG_4741|M.smegmatis_MC2_155 --TSLSAEVIGPAATFEDVVKIGERDQHVIEIATVLIVLMILIIVYRNLV
MAB_0937c|M.abscessus_ATCC_199 -GSPTTVHITGPAATVADLTVAGQQDRLPIEIAIAVLVLAVLLLVYRSAL
MAV_1761|M.avium_104 AATSLTVSLTGPAATVADLTVAGERDRLPIELAIAVLVLVVLLVVYRSAV
MLBr_01231|M.leprae_Br4923 AGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPI
MUL_0757|M.ulcerans_Agy99 --PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSII
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 TALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
TH_3450|M.thermoresistible__bu TALLPLLVIGVSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
MMAR_4836|M.marinum_M TALLPLLVIGVSLAVGRGVLSALGESGMP-VSQFTIAFMTVILLGAGTDY
Mb1549c|M.bovis_AF2122/97 TMLVPLATIGASVVTAQGTLSGLAEFGLA-VNMQAIVFMSAVMIGAGTDY
Rv1522c|M.tuberculosis_H37Rv TMLVPLATIGASVVTAQGTLSGLAEFGLA-VNMQAIVFMSAVMIGAGTDY
MSMEG_4741|M.smegmatis_MC2_155 AMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQTLMLMTAMMMGAGTDY
MAB_0937c|M.abscessus_ATCC_199 TMMLPLVTIGSSLVIAQSVVAAYSQLTGAGVSNQSIVFLSAILAGAGTDY
MAV_1761|M.avium_104 TMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQSIVFLSAIMAGAGTDY
MLBr_01231|M.leprae_Br4923 TMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDY
MUL_0757|M.ulcerans_Agy99 TAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDY
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 TVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFLA
TH_3450|M.thermoresistible__bu TVFLISRYHEQRRAQ----VAPEQAAIYATASIGRVILASAATVAFAFLA
MMAR_4836|M.marinum_M SVFLISRYHEQRRQN----VPPDLSVINATATIGRVILASAATVAFAFLA
Mb1549c|M.bovis_AF2122/97 AVFLISRYHDYVRHG----EKSDMAVKKALMSIGKVITASAATVAVTFLA
Rv1522c|M.tuberculosis_H37Rv AVFLISRYHDYVRHG----EKSDMAVKKALMSIGKVITASAATVAVTFLA
MSMEG_4741|M.smegmatis_MC2_155 AIFLFSRYHECVRSG----LSSDDAVVEALDSIGKVIAGSAGTVAITFMG
MAB_0937c|M.abscessus_ATCC_199 AVFLISRYHDYLRSG----KNYDQAVRAAMMSIGKVITASATTVGITFLL
MAV_1761|M.avium_104 AVFLISRYHDFLRRG----DDFDQAVRKALISIGKVITASASTVGITFLL
MLBr_01231|M.leprae_Br4923 AVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLG
MUL_0757|M.ulcerans_Agy99 AIFLIGRYQEARGLG----QDRESAYYTMFGGTAHVVLGSGLTIAGATFC
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAERG-IGEPKSD
TH_3450|M.thermoresistible__bu MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLALAAKRG-IGDPKPD
MMAR_4836|M.marinum_M MVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRG-IGEPKAD
Mb1549c|M.bovis_AF2122/97 MVFTKLEVFSAVGPAIAVAITVSLLGAVTLLPAILTLTGRRG-WIKPRRD
Rv1522c|M.tuberculosis_H37Rv MVFTKLEVFSAVGPAIAVAITVSLLGAVTLLPAILTLTGRRG-WIKPRRD
MSMEG_4741|M.smegmatis_MC2_155 LAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMVVLAGRRG-WVKPRKD
MAB_0937c|M.abscessus_ATCC_199 LSFAKMGVFQTVGVSSAIGIGVAYLSGMTLLPAILVLAGPRG-WVKPRRE
MAV_1761|M.avium_104 IGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIMVLAGPRG-WIRPRRE
MLBr_01231|M.leprae_Br4923 MSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRG-WVAPRRD
MUL_0757|M.ulcerans_Agy99 LSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRM
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 RTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQPA
TH_3450|M.thermoresistible__bu RTRRYWNSVAVAVVRRPVTLLTISLAVLLALSAVAVTINISYDDRKGQPA
MMAR_4836|M.marinum_M RTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYDDRRGQPA
Mb1549c|M.bovis_AF2122/97 LTSRMWRRSGVRIVRRPTIHLVGSLIVLVALAGCTLLIRFNYDDLKTVPQ
Rv1522c|M.tuberculosis_H37Rv LTSRMWRRSGVRIVRRSTIHLVGSLIVLVALAGCTLLIRFNYDDLKTVPQ
MSMEG_4741|M.smegmatis_MC2_155 LTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCAMLVNFNYDDRKNLPD
MAB_0937c|M.abscessus_ATCC_199 LTAQFWRRSGIRIVRRPIPHLVASVLVLALLGSCALLARYNYDDRKAVSP
MAV_1761|M.avium_104 LTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCAGLVRYNYDDRKALRP
MLBr_01231|M.leprae_Br4923 RAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYDDRKQIPA
MUL_0757|M.ulcerans_Agy99 ARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPA
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 TTASNQGYHLLDRHFRKDVVITEFLVVENPTDMRTGKGLADLDEMASRVS
TH_3450|M.thermoresistible__bu DTASNQGYQLLDRHFRKDVVFTEFLVVENPTDMRTGKGLADLDEMASRVA
MMAR_4836|M.marinum_M TTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLDEMASRVS
Mb1549c|M.bovis_AF2122/97 HVESVKGYEAMNRHFPMNAMTPMVLFIKSPRDLRTPGALADIEMMSREIA
Rv1522c|M.tuberculosis_H37Rv HVESVKGYEAMNRHFPMNAMTPMVLFIKSPRDLRTPGALADIEMMSREIA
MSMEG_4741|M.smegmatis_MC2_155 DAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRSPKALADMEQMAQRVS
MAB_0937c|M.abscessus_ATCC_199 SAPSSVGYAALERHFPLSQSIPEYILIQSPRDLRTPQALADLEQMASRIA
MAV_1761|M.avium_104 SAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRTPQALADLEQLADRVS
MLBr_01231|M.leprae_Br4923 SDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMAELAQRVS
MUL_0757|M.ulcerans_Agy99 DLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIF
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 QIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLA
TH_3450|M.thermoresistible__bu QIPGVTKVSGVTRPTGERLDQAKLAWQNQQIGDKMADAVADGNARKADLA
MMAR_4836|M.marinum_M QLPGVTKVSGVTRPTGARLDQAQLSWQNGEIGDKMAGAVAKGDAHKDDLA
Mb1549c|M.bovis_AF2122/97 ELPNIVMVRGLTRPNGEPLKETKVSFQAGEVGGKLDEATTLLEEHGGELD
Rv1522c|M.tuberculosis_H37Rv ELPNIVMVRGLTRPNGEPLKETKVSFQAGEVGGKLDEATTLLEEHGGELD
MSMEG_4741|M.smegmatis_MC2_155 QLPDIEMVRGVTRPTGEMLQEARATWQAGEVGGKLNDASTLIDANDANLS
MAB_0937c|M.abscessus_ATCC_199 QLPDVGLVSGVTRPLGEVPPEFRATYQAGLVGTRLADGSNQINQRSSDLN
MAV_1761|M.avium_104 QLPNVSVVSGITRPTGNVPEQFRATYQAGAIGSMLAGGSTMINDQTDDLN
MLBr_01231|M.leprae_Br4923 QIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQLGSASHLIGESTGDLN
MUL_0757|M.ulcerans_Agy99 GVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSML
Mflv_4635|M.gilvum_PYR-GCK ---------------------MPFILSSRTLFGPQSG--EQRARQPLLQQ
Mvan_0312|M.vanbaalenii_PYR-1 KLTGGADQLADGLAQLDSTVRTALTPLAEILTQAQSAGTQVNQFRPLLQQ
TH_3450|M.thermoresistible__bu KLTNGADQLAAGLAQLDTTLRTALAPLSGILSQAQSAGTQMQQFRPLLQQ
MMAR_4836|M.marinum_M KLTHGADQLAGGLAQLDTTLRTALTPLTGLLTQAQSSGSQVQRFRPLLQQ
Mb1549c|M.bovis_AF2122/97 QLTGGAHQLADALAQIRNEINGAVASSSGIVNTLQAMMDLMGGDK-TIRQ
Rv1522c|M.tuberculosis_H37Rv QLTGGAHQLADALAQIRNEINGAVASSSGIVNTLQAMMDLMGGDK-TIRQ
MSMEG_4741|M.smegmatis_MC2_155 TLSGGAHKLADVLGQISTQVTNALVTVRPLAGALADMETKYGGEK-TLDQ
MAB_0937c|M.abscessus_ATCC_199 RLTSGANTLAGSLTDLRNQLNKITPGLQSLLEASNSLKTKSGGDE-LVRN
MAV_1761|M.avium_104 RLARGAGTLADNLGDVRGQVNQLAASVRELENAFSSTKNQYSGDA-LVNQ
MLBr_01231|M.leprae_Br4923 RLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQKMFGDSK-TLGE
MUL_0757|M.ulcerans_Agy99 QQVNDIQTNIDQMERMHDLT---------------------------QQM
Mflv_4635|M.gilvum_PYR-GCK LSATAPAVDQAIQSGPGLRPLANQAQNAITQLDPLVGALNTSPWCATTPQ
Mvan_0312|M.vanbaalenii_PYR-1 LSATAPAVDQAIQSSPGLRPLANQAQNAISQLDPLVGALNTSPWCATTPQ
TH_3450|M.thermoresistible__bu LSATAPAVDQAIQAGPGLRPWADQAAHAIAILDPLVGALNTAPWCATTPQ
MMAR_4836|M.marinum_M LSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPWCATTPE
Mb1549c|M.bovis_AF2122/97 LENASQYVGRMRALGDNLSGTVTDAEQIATWASPMVNALNSSPVCNSDPA
Rv1522c|M.tuberculosis_H37Rv LENASQYVGRMRALGDNLSGTVTDAEQIATWASPMVNALNSSPVCNSDPA
MSMEG_4741|M.smegmatis_MC2_155 IDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMVRALNVSPECNLDPA
MAB_0937c|M.abscessus_ATCC_199 VDNAAKLVDEINALANDMGWNFSAAKDMFGWINPVLAALQGNPICDADTS
MAV_1761|M.avium_104 VDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVLAALQGNPVCDADSS
MLBr_01231|M.leprae_Br4923 IDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIALDSSVLCDTNPI
MUL_0757|M.ulcerans_Agy99 ADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPV
. : * . . .: : * .
Mflv_4635|M.gilvum_PYR-GCK CAQIRDQVKILVTLRDSGFFTQIADLGDRY--DPATNATVGGTLANVQNA
Mvan_0312|M.vanbaalenii_PYR-1 CAQIRDQVKILVTLRDSGFFTQIADLGDRY--DPATNATVGGTLANVQNA
TH_3450|M.thermoresistible__bu CAQIRDQVQVLVTLRNSGFFNQVADLGDRY--NPATGATVAETLADIRNA
MMAR_4836|M.marinum_M CTQLRDQVQILVTLRHTGFFNQLANLGDLY--QPGS-DTAAGTVADVQNT
Mb1549c|M.bovis_AF2122/97 CRTSRAQLAAIVQAQDDGLLRSIRALAVTLQQTQ-EYQTLARTVSTLDGQ
Rv1522c|M.tuberculosis_H37Rv CRTSRAQLAAIVQAQDDGLLRSIRALAVTLQQTQ-EYQTLARTVSTLDGQ
MSMEG_4741|M.smegmatis_MC2_155 CAASRSDLQRIVEAKDNGNLDKFAELGRQLESTE-GDETLDEAVSGLQQS
MAB_0937c|M.abscessus_ATCC_199 CSNTRGQFERLVGERNSGRLDEIERLAHQLGNSPGNKATLSTTVTKLNAS
MAV_1761|M.avium_104 CSATRATFEQLVGPRGQADLDAIDDLSHQLQAYP-DKRALKASTDRLRNA
MLBr_01231|M.leprae_Br4923 CADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQ-SSQTIGATVSGLEKT
MUL_0757|M.ulcerans_Agy99 CWSLRSVFDTLDG-----------------------VDLMTEDINNLLPL
* * . : :
Mflv_4635|M.gilvum_PYR-GCK VASLDKAFG--ALGDPADLATNLRRLQDGIGQLASGAQALATGVRTLADS
Mvan_0312|M.vanbaalenii_PYR-1 VASLDKAFG--ALGDPADLATNLRRLQDGIGQLASGAQALATGVRTLADS
TH_3450|M.thermoresistible__bu VTAMDKAFG--ALGDPADLAGNIGRLQDGISQLASGAQALATGVHTLVDS
MMAR_4836|M.marinum_M ITSLDKTFG--ALGDPADLAGNIRRLQSGISQLASGAQALATGVHTLADS
Mb1549c|M.bovis_AF2122/97 LKQVVST-----LKAVDGLPTKLAQMQQGANALADGSAALAAGVQELVDQ
Rv1522c|M.tuberculosis_H37Rv LKQVVST-----LKAVDGLPTKLAQMQQGANALADGSAALAAGVQELVDQ
MSMEG_4741|M.smegmatis_MC2_155 IKEATAAARELGLEDASSVKRQLDQLEQGVNLLADSSHQLAQGVQLLVDQ
MAB_0937c|M.abscessus_ATCC_199 LLSVVNGLHAMGLDKPGGPQAGLNQLRQGADRLAGGSQQVAGGVDQLVGQ
MAV_1761|M.avium_104 FAKLNDVLRAMGMDRPGGLQSNLTTLQNGADQFAGGSRQVADAVAQLVDK
MLBr_01231|M.leprae_Br4923 LTAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAGRRIADGVAVLVDQ
MUL_0757|M.ulcerans_Agy99 MERLDTLMP--------QMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQ
. : : . : : * ..
Mflv_4635|M.gilvum_PYR-GCK NIEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANAFENRQFTDVAEQF
Mvan_0312|M.vanbaalenii_PYR-1 NIEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANAFENRQFTDVAEQF
TH_3450|M.thermoresistible__bu NLEMLSGMSQIATQLQNSARASADSDSSSGFYLPPNTFENRQFADVAKQF
MMAR_4836|M.marinum_M NIEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFENRQFADVAKHF
Mb1549c|M.bovis_AF2122/97 VKKMGSGLNEAADFLLGIKRDADKP-SMAGFNIPPQIFSRDEFKKGAQIF
Rv1522c|M.tuberculosis_H37Rv VKKMGSGLNEAADFLLGIKRDADKP-SMAGFNIPPQIFSRDEFKKGAQIF
MSMEG_4741|M.smegmatis_MC2_155 TRNMGQGLDQASQFLLAMKRDASDP-QMSGFYIPPQILTQEEFNKAAALF
MAB_0937c|M.abscessus_ATCC_199 IKVIVNGLNQASNFLLTMKTNAADP-SQAGFNIPAEVLNNPDFQRAAKAF
MAV_1761|M.avium_104 VKQLGAGLSESAAFLLSLKHDAAHP-AMAGFNIPAQLLRLPQFQEAAKVF
MLBr_01231|M.leprae_Br4923 TRTMGTSLARASAFLMEMGQDASQP-SMAGFNVPPQLLNTEDFKKLVQAF
MUL_0757|M.ulcerans_Agy99 MAAMQEDSSAMGEAFDSSR-------NDDSFYLPPEVFNNPDFKRGLEQF
: . . : .* :*.: : :* *
Mflv_4635|M.gilvum_PYR-GCK LSPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSV
Mvan_0312|M.vanbaalenii_PYR-1 LSPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSV
TH_3450|M.thermoresistible__bu LSPDGKTARFAIESSHDPYSVDAMNLAHTITDVADAARPNTSLAHATVSV
MMAR_4836|M.marinum_M LSPDGKTARFAIESSYDPYSSDAMNLAHKITEVADAARPNTSLANATVSM
Mb1549c|M.bovis_AF2122/97 LSADGHAARYFVQSALNPATTEAMDQVNDILRVADSARPNTELEDATIGL
Rv1522c|M.tuberculosis_H37Rv LSADGHAARYFVQSALNPATTEAMDQVNDILRVADSARPNTELEDATIGL
MSMEG_4741|M.smegmatis_MC2_155 VSPDGRSVRYLVQTALDPFGTAAMDQVKDIVKTAESARPNTSLTDAKISL
MAB_0937c|M.abscessus_ATCC_199 ISPDGHSVRYLVQTKLNPFSPEAMDQVNQISDVAKGAQPNTTLADATISM
MAV_1761|M.avium_104 ISPDGHSVRYLVQSKLSPFSTQAMDQVDAITATARGAQPNTALADAEVSM
MLBr_01231|M.leprae_Br4923 ISPDGHSVRYFIQTDLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYL
MUL_0757|M.ulcerans_Agy99 LSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYL
:*.**::.*: :. .* .:: * .* * .* * : : :
Mflv_4635|M.gilvum_PYR-GCK AGFPAVNSDIQRFLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTV
Mvan_0312|M.vanbaalenii_PYR-1 AGFPAVNSDIQRLLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTV
TH_3450|M.thermoresistible__bu AGFPAVNSDIARLLWADFAQLAIATIVIVGLILVLLLRALLAPIYLLGTV
MMAR_4836|M.marinum_M AGFPAVNSDIQRLLSADFHQLAFATLVIVGLILVVLLRALVAPLYLLGTV
Mb1549c|M.bovis_AF2122/97 AGVPTALRDIRDYYNSDMKFIVIATIVIVFLILVILLRALVAPIYLIGSV
Rv1522c|M.tuberculosis_H37Rv AGVPTALRDIRDYYNSDMKFIVIATIVIVFLILVILLRALVAPIYLIGSV
MSMEG_4741|M.smegmatis_MC2_155 VGFSSIQNEMRNYYDGDLRFIITVTLIVVFLILAALLRSIIAPIYLVLSV
MAB_0937c|M.abscessus_ATCC_199 GGFPTALRDTRDYYQHDIQFIIAATLIVVLLTLMVLLRAIVAPLYLVGSV
MAV_1761|M.avium_104 AGYTVGLKDTRDYYQHDIKFIIAVTLLVVLLTLMALLRAIVAPLYLVATV
MLBr_01231|M.leprae_Br4923 SGYTVTLRDTRDYYDRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSV
MUL_0757|M.ulcerans_Agy99 GGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTV
* : *: :: :: : : : *:::*. :: :*
Mflv_4635|M.gilvum_PYR-GCK VLNYLASLGIGVVVFQWGLGHEIAWPVPLLAFIILVAVGADYNMLLVSRL
Mvan_0312|M.vanbaalenii_PYR-1 VLNYLASLGIGVVVFQWGLGHEIAWPVPLLAFIILVAVGADYNMLLVSRL
TH_3450|M.thermoresistible__bu VLNYLASLGIGVLVFQYLLGHEIAWPVPLLAFIILVAVGADYNMLLVSRL
MMAR_4836|M.marinum_M VLNYGAALGLGTLVFQYGLGKEIAWPVPLLAFIILVAVGADYNMLLISRL
Mb1549c|M.bovis_AF2122/97 LISYLSALGIGTLVFQLILGQEMHWSLPGLSFILLVAIGADYNMLLISRI
Rv1522c|M.tuberculosis_H37Rv LISYLSALGIGTLVFQLILGQEMHWSLPGLSFILLVAIGADYNMLLISRI
MSMEG_4741|M.smegmatis_MC2_155 VLSYMSALGIGVVFFQFILGKEIVWTVPGMAFLVLVAVGADYNLLLISRI
MAB_0937c|M.abscessus_ATCC_199 VLSYFAAIGIGVLTFQYLLGEQLHWTVPPLAFVVLVAVGADYNMLFVSRM
MAV_1761|M.avium_104 VISYLSAVGVGVLVFQFLLGQQLHWSVPPLAFVVLVAVGADYNMLLVSRM
MLBr_01231|M.leprae_Br4923 IVSYLSALGLCVLVFQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRL
MUL_0757|M.ulcerans_Agy99 VLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARL
::. ::.*: .: :* * :: * : ::.::*:*:*****:*: :*:
Mflv_4635|M.gilvum_PYR-GCK REESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQAGL
Mvan_0312|M.vanbaalenii_PYR-1 REESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQAGL
TH_3450|M.thermoresistible__bu REESGTNIRVGVLRTVANTGSVITSAGVIFAASMFGLMFGSIAIMIQAGF
MMAR_4836|M.marinum_M REESAHNIRVGVLRTVANTGSVITSAGLIFAASMFGLIAGSIAIMIQAGF
Mb1549c|M.bovis_AF2122/97 RDESPHGIRIGVIRTVGSTGGVITSAGLIFAASMFGLVGANINTMAQAGF
Rv1522c|M.tuberculosis_H37Rv RDESPHGIRIGVIRTVGSTGGVITSAGLIFAASMFGLVGASINTMAQAGF
MSMEG_4741|M.smegmatis_MC2_155 RDEAAHGMRTAVIRTIGATGGVITSAGLIFAASMFGLTFSSLLAAVQIGF
MAB_0937c|M.abscessus_ATCC_199 RDESASSVRYGIIRALNSTGGVITAAGLIFAASVGGLLFSSIGIVVQGGF
MAV_1761|M.avium_104 RDESPHSMRYGIIRTLSSTGGVITAAGLIFAASMSGLLFSSIGTVVQGGV
MLBr_01231|M.leprae_Br4923 RDESSHGLRASVIRTVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGF
MUL_0757|M.ulcerans_Agy99 KEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGT
::* .:. .::*:: :*.*:*:**::** :: .: ..: * *
Mflv_4635|M.gilvum_PYR-GCK IIGFGLLLDTFLVRTLTVPAIATLLREASWWPT-----------------
Mvan_0312|M.vanbaalenii_PYR-1 IIGFGLLLDTFLVRTLTVPAIATLLREASWWPT-----------------
TH_3450|M.thermoresistible__bu IVGCGLLLDTFLVRTLTVPAIATLLREASWWP------------------
MMAR_4836|M.marinum_M IIGCGLLLDTFVVRTLTVPAIATLLREASWWPQ-----------------
Mb1549c|M.bovis_AF2122/97 TIGIGIVLDTFLVRTVTVPALTTMIGRANWWPSELGRDPSTPPTKADRWL
Rv1522c|M.tuberculosis_H37Rv TIGIGIVLDTFLVRTVTVPALTTMIGRANWWPSELGRDPSTPPTKADRWL
MSMEG_4741|M.smegmatis_MC2_155 IIGVGLLLDTFLVRTITVPAAAVLIGKLSWWP------------------
MAB_0937c|M.abscessus_ATCC_199 VIGVGILLDTFVVRTITVPAIAALVGKANWWP------------------
MAV_1761|M.avium_104 VIGVGILLDTFLVRTVTVPAIAALAGRANWWP------------------
MLBr_01231|M.leprae_Br4923 VLGSGILLDTFIVRTITVPAVAALLRRASWWP------------------
MUL_0757|M.ulcerans_Agy99 TIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVR--------------
:* *:::**::**:. .*: :.: . ***
Mflv_4635|M.gilvum_PYR-GCK --------KATNPRRGDPKQKA----------------------------
Mvan_0312|M.vanbaalenii_PYR-1 --------KATNPRRGDPKQKA----------------------------
TH_3450|M.thermoresistible__bu -----------QPNRAR---------------------------------
MMAR_4836|M.marinum_M --------RKPLTHNG----------------------------------
Mb1549c|M.bovis_AF2122/97 RRVKGHRRKAPIPAPKPPHTKVVRNTNGHASKAATKSVPNGKPADLAEGN
Rv1522c|M.tuberculosis_H37Rv RRVKGHRRKAPIPAPKPPHTKVVRNTNGHASKAATKSVPNGKPADLAEGN
MSMEG_4741|M.smegmatis_MC2_155 -------TKPPAPEPAPTEPTVAP-----AAQA-----------------
MAB_0937c|M.abscessus_ATCC_199 -------SQVNARQTSSAKPSAAAPAG-----------------------
MAV_1761|M.avium_104 -------SRIAVRRN----PVSGQP-------------------------
MLBr_01231|M.leprae_Br4923 -------ARPWGNNA-----------------------------------
MUL_0757|M.ulcerans_Agy99 --------QRPAPQPWPTPAPTPPPATTSV--------------------
Mflv_4635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3450|M.thermoresistible__bu --------------------------------------------------
MMAR_4836|M.marinum_M --------------------------------------------------
Mb1549c|M.bovis_AF2122/97 GEYLIDHLRRHSLPLFGYAAMPAYDVVDGVSKPNGDGAHIGKEPVDHLLG
Rv1522c|M.tuberculosis_H37Rv GEYLIDHLRRHSLPLFGYAAMPAYDVVDGVSKPNGDGAHIGKEPVDHLLG
MSMEG_4741|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_1761|M.avium_104 --------------------------------------------------
MLBr_01231|M.leprae_Br4923 --------------------------------------------------
MUL_0757|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4635|M.gilvum_PYR-GCK ----------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1 ----------------------------------------
TH_3450|M.thermoresistible__bu ----------------------------------------
MMAR_4836|M.marinum_M ----------------------------------------
Mb1549c|M.bovis_AF2122/97 H---------------------------------------
Rv1522c|M.tuberculosis_H37Rv HSLPLFGLAGLPSYDRWDDTSIGEPAVGHAGSKPDAKLST
MSMEG_4741|M.smegmatis_MC2_155 ----------------------------------------
MAB_0937c|M.abscessus_ATCC_199 ----------------------------------------
MAV_1761|M.avium_104 ----------------------------------------
MLBr_01231|M.leprae_Br4923 ----------------------------------------
MUL_0757|M.ulcerans_Agy99 ----------------------------------------