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MLALTDARERAAQCGIPDAMAELSVFRIALHQPPVAVALHGMLEALLWKGALDARLRELIIMRIGWVTDS VYEWTQHWRVARLLDVPERDLLGVRDWQNAGHFGEAERAVLAATDETLRDGTISDETWAECQRALHGDPA VLVELVAAIGNWRLFSALLRSLHVPLEDGLEGWPPDGVRPSVD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4627 | - | - | 100% (183) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_0137 | - | 2e-10 | 31.14% (167) | carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_2440 | - | 6e-10 | 36.70% (109) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 7e-58 | 54.44% (180) | hypothetical protein Mb1558 |
| M. tuberculosis H37Rv | Rv1531 | - | 7e-58 | 54.44% (180) | hypothetical protein Rv1531 |
| M. leprae Br4923 | MLBr_02465 | - | 7e-08 | 27.20% (125) | hypothetical protein MLBr_02465 |
| M. abscessus ATCC 19977 | MAB_2040c | - | 5e-72 | 68.89% (180) | hypothetical protein MAB_2040c |
| M. marinum M | MMAR_3164 | - | 8e-72 | 69.95% (183) | hypothetical protein MMAR_3164 |
| M. avium 104 | MAV_3238 | pcaC | 7e-58 | 56.11% (180) | hypothetical protein MAV_3238 |
| M. smegmatis MC2 155 | MSMEG_6536 | - | 5e-10 | 31.36% (118) | carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_2018 | - | 4e-09 | 27.98% (168) | carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 2e-06 | 23.95% (167) | hypothetical protein MUL_4533 |
| M. vanbaalenii PYR-1 | Mvan_4316 | - | 4e-12 | 35.04% (137) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 ---------------------------MTTSRVPLLPVDEAKAAADEAGV
Rv1531|M.tuberculosis_H37Rv ---------------------------MTTSRVPLLPVDEAKAAADEAGV
MAV_3238|M.avium_104 ---------------------------MPTARLPKLPLDEAKAAADEAAV
MAB_2040c|M.abscessus_ATCC_199 --------------------------MTMAERVPMLDREQAQLRAAECGL
MMAR_3164|M.marinum_M --------------------------MTRTERVPMLDLEQARLRAAECGL
Mflv_4627|M.gilvum_PYR-GCK ----------------------------------MLALTDARERAAQCGI
MSMEG_6536|M.smegmatis_MC2_155 --------------------------MLPPLPAEDWDDAARDALASVV--
TH_2018|M.thermoresistible__bu -------------------------VRLAPLPAEQWDDEVLSALAVML--
Mvan_4316|M.vanbaalenii_PYR-1 MPFEPRPSHPRQRRTQHMNSTDGAESLLAPLTAAEWGDDEYAAFGALLGL
MLBr_02465|M.leprae_Br4923 -----------------MSGGTGTGPVGRIPPGSLRQLGPINWVIAKLAA
MUL_4533|M.ulcerans_Agy99 -----------------MTG----DQVARIPSGGIRQLGPVNWALAKLAA
Mb1558|M.bovis_AF2122/97 PDYMAELSIFQVLLN------------HPRLARTFNDLLATMLWHGTLDS
Rv1531|M.tuberculosis_H37Rv PDYMAELSIFQVLLN------------HPRLARTFNDLLATMLWHGTLDS
MAV_3238|M.avium_104 PNYMAELSIFQVLLN------------HPPLARAINDLLATMLWHGALDS
MAB_2040c|M.abscessus_ATCC_199 PEELAELSVFRVALH------------QPRVAVALYGLLDALLFRGSLDA
MMAR_3164|M.marinum_M PAEMAELSVFRVALH------------QPSLAVALYGMLEALLFNGVLDA
Mflv_4627|M.gilvum_PYR-GCK PDAMAELSVFRIALH------------QPPVAVALHGMLEALLWKGALDA
MSMEG_6536|M.smegmatis_MC2_155 PPERRDADGVGNALG--------VLVRHPELARHFLQFNNYLQRDSLLPE
TH_2018|M.thermoresistible__bu PEERRNPDGAGTALS--------TLVRHPRLTKAFLRFSNHLLFRSTLPP
Mvan_4316|M.vanbaalenii_PYR-1 PGEKVPRAGSGHAADPLKFDIIGLLARHPKMARRFLTFNGWLLQCGELPL
MLBr_02465|M.leprae_Br4923 SLLRTSEMHLFTILG------------QRQLLFWAWLIYGGRLLRGKLPR
MUL_4533|M.ulcerans_Agy99 RSVRAPEMHLFTALG------------YRQYLFWTWAIYSGRLLHGRLPR
: . *
Mb1558|M.bovis_AF2122/97 RLRELVIMRIGWLTDCDYEWTQHWRVASGLGVSADDLLGVRDWQGYN---
Rv1531|M.tuberculosis_H37Rv RLRELVIMRIGWLTDCDYEWTQHWRVASGLGVSADDLLGVRDWQGYN---
MAV_3238|M.avium_104 RLRELIIMRIGWLTGCDYEWTQHWRVASRLGVPGDDLLGVRDWRNYP---
MAB_2040c|M.abscessus_ATCC_199 RLRELVILRIGWITGSEYEWTQHWRIATLLGVPERDLLAVRDWQNSE---
MMAR_3164|M.marinum_M RLRELIIMRIGWVTGSVYEWTQHWRIATLLGVASDDLLAVRDWQSSN---
Mflv_4627|M.gilvum_PYR-GCK RLRELIIMRIGWVTDSVYEWTQHWRVARLLDVPERDLLGVRDWQNAG---
MSMEG_6536|M.smegmatis_MC2_155 RIRELVILRTAYRAGCVYEWGHHAAMGLLAGLTVDDVESAR--SGS----
TH_2018|M.thermoresistible__bu RLRELAVLRVAHRRSCDYEWAHHVFIGKAEGLTDDDIAGVQ--RGA----
Mvan_4316|M.vanbaalenii_PYR-1 RLRELAILRIAHTRRSAFFWGEHTKVATEGGVPEADIARLA--EGNE---
MLBr_02465|M.leprae_Br4923 VDTELVILRVAHLRTCEYELQHHRRMARKRGLDTKIQAMIFAWPDVPTGA
MUL_4533|M.ulcerans_Agy99 IDTELVILRVAHLRSCEYELQHHRRMARAAGLDAHAQATIFAWPDAPQGD
** ::* . . : .* :. .: .
Mb1558|M.bovis_AF2122/97 ----GFGPAEQAVLAATDDVVREGAVSAQSWSACERELHCDKVVLIELVT
Rv1531|M.tuberculosis_H37Rv ----GFGPAEQAVLAATDDVVREGAVSAQSWSACERELHCDKVVLIELVT
MAV_3238|M.avium_104 ----GFGPTERAVLAATDDVVRHGSVSAASWAQCEHEFKRDTTVLVELVT
MAB_2040c|M.abscessus_ATCC_199 ----SLGPVERAVLAATDDVVRDGVISEENWAGCQKAFNSDHAVLVELVG
MMAR_3164|M.marinum_M ----RLGHAERAVLAATDDVVRDGVIAEENWAACHKAFNGDHAVLVELVG
Mflv_4627|M.gilvum_PYR-GCK ----HFGEAERAVLAATDETLRDGTISDETWAECQRALHGDPAVLVELVA
MSMEG_6536|M.smegmatis_MC2_155 ----AADEFDQTVLDATDELVAGAQLSPETWTRLGRWLD--DRQRMDLMF
TH_2018|M.thermoresistible__bu ----VDDPFDQAVLDAVDELEEHYRISDATWATLGARLD--ERQLMDLVF
Mvan_4316|M.vanbaalenii_PYR-1 ----AFTGADRLVLDATDELLHDGHAEPATWHRLTDELG--THQAMELIF
MLBr_02465|M.leprae_Br4923 G----LSVRQQALLAATDEFVKDRKITSSSWQQLETHLD--RRRLIEFCM
MUL_4533|M.ulcerans_Agy99 GPRRVLSSRQQALLTATDELIKNRSVTPATWEQLEIHLN--RRRLIEFCL
:: :* *.*: .* : :::
Mb1558|M.bovis_AF2122/97 VISAWRMVASILHSLEVPLEDGVSSWPPDGLSPR------
Rv1531|M.tuberculosis_H37Rv VISAWRMVASILHSLEVPLEDGVSSWPPDGLSPR------
MAV_3238|M.avium_104 VIGAWRMVASILQSLEVPLEDGVASWPPDGREPAS-----
MAB_2040c|M.abscessus_ATCC_199 AIANWRLFSILLRSLNIPLESGTDGWPPDGRAPRRRD---
MMAR_3164|M.marinum_M AIANWRLFSILLRSLNIPLESGTDSWPPDGRAPRRDD---
Mflv_4627|M.gilvum_PYR-GCK AIGNWRLFSALLRSLHVPLEDGLEGWPPDGVRPSVD----
MSMEG_6536|M.smegmatis_MC2_155 TVGGYLTLAMALNTFEVQLEEG-AGRPEFYAPVGTAR---
TH_2018|M.thermoresistible__bu TVGCYGLMAMAYNTFGITPETG-R----------------
Mvan_4316|M.vanbaalenii_PYR-1 VVGTYAMLAMAFDTWRLPPPAGSASLPEPPAGVPPGGGTH
MLBr_02465|M.leprae_Br4923 LISQYDGLAATISSLDIPLDNSC-----------------
MUL_4533|M.ulcerans_Agy99 LATQYDALAATITALGVPLDNPR-----------------
: .: : :