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TEAKMDELGYYLLAGAGGEGPATLMDEARRGEELGFGTGFISERWNVKEASSLTGAALAVTSRMQIATAA TNHNTRHPLITGSWATTMHRLSGGRFTLGIGRGIGAIYNAFGIPTVTTAQMEDFAQVMRKLWHGELIFNH DGPLGKYQVLFLDPDFREDIRLAIVAFGPQTLALGGREFDDVILHTYFTPETLQRAVKTVKDAAEQAGRD PASVRVWSCFATVGDHLPEELRLKKTVARLATYLQGYGDLLVNTNGWDPAVLQRFRDDKVVQSIGGGIDH KATAEQIEHIATLIPDEWLEPSATGSPQQCADRVRKEFDYGADAVIMHGATPDELEPIVAAYRAGQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4328 | - | - | 100% (348) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4402 | - | 3e-15 | 29.97% (287) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_2493 | - | 1e-12 | 29.21% (178) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2975c | - | 6e-16 | 31.38% (188) | oxidoreductase |
| M. tuberculosis H37Rv | Rv2951c | - | 6e-16 | 31.38% (188) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 5e-12 | 29.68% (155) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2053 | - | 5e-13 | 27.57% (214) | luciferase-like |
| M. marinum M | MMAR_4003 | - | 1e-175 | 85.17% (344) | oxidoreductase |
| M. avium 104 | MAV_1607 | - | 1e-179 | 88.86% (341) | hypothetical protein MAV_1607 |
| M. smegmatis MC2 155 | MSMEG_2249 | - | 0.0 | 92.46% (345) | hypothetical protein MSMEG_2249 |
| M. thermoresistible (build 8) | TH_1627 | - | 0.0 | 90.59% (340) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3866 | - | 1e-175 | 84.59% (344) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2018 | - | 0.0 | 97.67% (343) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4328|M.gilvum_PYR-GCK -----------------------------MTEAKMDELGYYLLAGAG---
Mvan_2018|M.vanbaalenii_PYR-1 -----------------------------MTR-VLDELGFYLLAGAG---
MSMEG_2249|M.smegmatis_MC2_155 MNSRLFNSHRVVAGCVTECGIVVTNEEFDMSEHALDELGYYLLAGAG---
TH_1627|M.thermoresistible__bu MN------------------------------RPLDELGYYLLAGAG---
MAV_1607|M.avium_104 ---------------------------------MLDELGFYLLAGAG---
MMAR_4003|M.marinum_M -----------------------------MSDRTLNELGYYLLAGAG---
MUL_3866|M.ulcerans_Agy99 -----------------------------MSDRTLNELGYYLLAGAG---
Mb2975c|M.bovis_AF2122/97 -----------MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYW
Rv2951c|M.tuberculosis_H37Rv -----------MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYW
MLBr_00131|M.leprae_Br4923 -----------MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYW
MAB_2053|M.abscessus_ATCC_1997 ----------------------------------MSTYGVSVLG------
:
Mflv_4328|M.gilvum_PYR-GCK -GEGPATLMDEARRG-EELGFGTGFISERWNVKEASSLTG--AALAVTSR
Mvan_2018|M.vanbaalenii_PYR-1 -GEGPATLMDEARRG-EELGFGTGFISERWNVKEASSLTG--AALAVTSR
MSMEG_2249|M.smegmatis_MC2_155 -GEGPATLMDEARRG-EELGFGTAFISERWNVKEASSLVG--AACAVTTR
TH_1627|M.thermoresistible__bu -GEGPATLMDEARRG-EELGFGTAFISERWNVKEASSLVG--AACAVTER
MAV_1607|M.avium_104 -GEGPATLMDEARRG-EELGFGTAFISERWNVKEASSLVG--AACAVTHR
MMAR_4003|M.marinum_M -GEGPATLMDEARRG-EELGLGTAFVSERWNVKEASSLVG--AACAVTSR
MUL_3866|M.ulcerans_Agy99 -GEGPATLMDEARRG-EELGLGTAFVSERWNVKEASSLVG--AACAVTSR
Mb2975c|M.bovis_AF2122/97 VGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFG-LPSR
Rv2951c|M.tuberculosis_H37Rv VGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFG-LPSR
MLBr_00131|M.leprae_Br4923 VGDHLNALVPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNG
MAB_2053|M.abscessus_ATCC_1997 --ADLATLVETAEAT-DLAGFDAAWASEFYSRSGSISMAA---MAARTKR
:*: : . *. : .: . :: .
Mflv_4328|M.gilvum_PYR-GCK MQIATAATNHNTRHPLITGSWATTMHRLSGGRFTLGIGRGIGAIYNAFG-
Mvan_2018|M.vanbaalenii_PYR-1 MQIATAATNHNTRHPLITGSWATTMHRLSGGRFTLGIGRGIGAIYNAFG-
MSMEG_2249|M.smegmatis_MC2_155 MQIATAATNHNTRHPLITGSWATTMHRLSGGRFTLGIGRGIAAMYGAFG-
TH_1627|M.thermoresistible__bu MQIATAATNHNTRHPLITGSWATTMHRLSGGRFTLGIGRGVAAMYAAFG-
MAV_1607|M.avium_104 MQIATAATNHNTRHPLITGSWATTMHRLSGGRFTLGVGRGIAAIYGAFG-
MMAR_4003|M.marinum_M MQIATAATNHNTRHPLVTASWATTMHRLSGGRFTLGIGRGIAAIYGAFG-
MUL_3866|M.ulcerans_Agy99 MQIATAATNHNTRHPVVTASWATTMHRLSGGRFTLGIGRGIAAIYGAFG-
Mb2975c|M.bovis_AF2122/97 LRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYG-
Rv2951c|M.tuberculosis_H37Rv LRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYG-
MLBr_00131|M.leprae_Br4923 LRLGVCVTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGEREGNEPYG-
MAB_2053|M.abscessus_ATCC_1997 CRIGSSILYGVGRSPLVLATEARDLDELSGGRVVLGLGNGTRRMMSDWHG
::. . * * : . * :. *: *: **:* * :
Mflv_4328|M.gilvum_PYR-GCK -IPTVT-TAQMEDFAQVMRKLWH--GELIFNHDGPLGKYQVLFLDPDFR-
Mvan_2018|M.vanbaalenii_PYR-1 -IPTVT-TAQMEDFAQVMRKLWH--GELIFNHDGPLGKYQVLFLDPDFR-
MSMEG_2249|M.smegmatis_MC2_155 -IPSVT-TAQMEDFAQVMRRLWQ--GEVIFNHDGPIGNYQVLFLDPDFR-
TH_1627|M.thermoresistible__bu -IPPVT-TAQMEDFAQVMRRLWR--GEVIFDHDGPIGRYQVLFLDPDFN-
MAV_1607|M.avium_104 -IPAVT-TAQMEDWAGVMRRLWH--GELIFNHDGPMGKYPILFLDPDFN-
MMAR_4003|M.marinum_M -IPAVT-TAQMEDWAQVMRRLWK--GEMIFNHDGPMGRYPVLFLDPDFN-
MUL_3866|M.ulcerans_Agy99 -IPAVT-TAQMEDWAQVMRRLWK--GEMVFNHDGPMGRYPVLFLDPDFN-
Mb2975c|M.bovis_AF2122/97 -VEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRG
Rv2951c|M.tuberculosis_H37Rv -VEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRG
MLBr_00131|M.leprae_Br4923 -VEWTKPVARFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRG
MAB_2053|M.abscessus_ATCC_1997 VEDTSAPALRMEELVPLVRRIWNLHEGPVRHEGRFYRMNLVPTGDVAPPQ
. :::: :* :* : ..
Mflv_4328|M.gilvum_PYR-GCK EDIRLAIVAFGPQTLALGGREFDDVILHTYFTPETLQRAVK-TVKDAAEQ
Mvan_2018|M.vanbaalenii_PYR-1 EDIRLAIVAFGPQTLALGGREFDDVILHTYFTPETLQRAVR-TVKDAAEQ
MSMEG_2249|M.smegmatis_MC2_155 EDIRLAIVAFGPQTLALGGREFDDVILHTYFTPETLQRAVK-TVKTAAEQ
TH_1627|M.thermoresistible__bu EDIRLAIVAFGPQTLALGGRMFDDVILHTYFTPETLQRAVK-TVKDAAEQ
MAV_1607|M.avium_104 EDIRLALVAFGPNTLALGGRVFDDVILHTYFTPETLQRSVK-TVKSAAEK
MMAR_4003|M.marinum_M EDIRLALVALGPKSLALGGRVFDDVILHTYFTPETLQRCVS-IVKTAADR
MUL_3866|M.ulcerans_Agy99 EDIRLALVALGPKSLALGGRVFDDVILHTYFTPETLQRCVS-IVKTAADR
Mb2975c|M.bovis_AF2122/97 KWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALE-AVRSAASD
Rv2951c|M.tuberculosis_H37Rv KWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALE-AVRSAASD
MLBr_00131|M.leprae_Br4923 KWPEIWVAAHGPRMLQATGRYADAWIPIVLVRPTDYSCALE-VVRTAASD
MAB_2053|M.abscessus_ATCC_1997 RAIPIITAGVRPRMCEVAGRVADGLAGHPLFTTTYVEEVARPAVVRGAER
. : .. *. ** * . . . * .*.
Mflv_4328|M.gilvum_PYR-GCK AGRDPASVRVWSCFATVGDHLPEELRLKKTVARLATYLQGYGDLLVNTNG
Mvan_2018|M.vanbaalenii_PYR-1 AGRDPASVRVWSCFATVGDHLPEELRLKKTVARLATYLQGYGDLLVNTNG
MSMEG_2249|M.smegmatis_MC2_155 AGRDPGSVRVWSCFATVGDHLPEELRLKKTVARLATYLQGYGDLLVNTNG
TH_1627|M.thermoresistible__bu AGRDPAEVRVWSCFATVGDHLPEELRLKKTVARLATYLQGYGDLLVETNG
MAV_1607|M.avium_104 AGRDPDSVRVWSCFATVGDHLPEQLRLKKTVARLATYLQGYGDLLVRTND
MMAR_4003|M.marinum_M AGRDPASVRVWSCFATVGDHLPEQLRLKKTVARLATYLQGYGDLLVHTNN
MUL_3866|M.ulcerans_Agy99 AGRDPASVRVWSCFATVGDHLPEQLRLKKTVARLATYLQGYGDLLVHTNN
Mb2975c|M.bovis_AF2122/97 AGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHG
Rv2951c|M.tuberculosis_H37Rv AGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHG
MLBr_00131|M.leprae_Br4923 AGRDPMSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHG
MAB_2053|M.abscessus_ATCC_1997 AGRDPADIEIVSMVICAVHDDPQIARREAAQQIAFYSSVKTYEHVLDVSG
***** .: : : .
Mflv_4328|M.gilvum_PYR-GCK WD---PAVLQRFRDDKVVQSIGGGIDHKATAEQIEHIATLIPDEWLEPSA
Mvan_2018|M.vanbaalenii_PYR-1 WD---PAVLQRFRDDKVVQSVGGGIDHKATAEQIEHIATLIPDEWLAPSA
MSMEG_2249|M.smegmatis_MC2_155 WD---PAVLQRFRDDKVVQSIPGGIDHKATAEQIEHIATLIPDEWLEPSA
TH_1627|M.thermoresistible__bu WD---PAVLRKFRDDPVVQSIPGGIDHKATPEQIEHIATLIPDEWLEPAA
MAV_1607|M.avium_104 WD---SAVLQRFRDDPVVTSIAGGIDHKATPEQIEHIATLIPDEWLEPSA
MMAR_4003|M.marinum_M WD---PAVLQRFREDPVVTSVRGGIDHKATAEQIEHIATLLPDEWLEPSA
MUL_3866|M.ulcerans_Agy99 WD---PAVLQRFREDPVVTSVRGGIDHKATAEQIEHIATLLPDEWLEPSA
Mb2975c|M.bovis_AF2122/97 VE---HPMGADFSG--VQDIIPQTMDKQTVLSYAAKVPAALMKEVVFS--
Rv2951c|M.tuberculosis_H37Rv VE---HPMGADFSG--VQDIIPQTMDKQTVLSYAAKVPAALMKEVVFS--
MLBr_00131|M.leprae_Br4923 VE---HPMGADFAG--VQDIIPQTIDEETVVSYAAKVPAALMKEVLFS--
MAB_2053|M.abscessus_ATCC_1997 FARQGAAIRDAFARRDLPAMFAAVTDDMIDAMAVAGTAAEVREGLRRY--
.: * : . *. .: : .
Mflv_4328|M.gilvum_PYR-GCK TGSPQQCADRVRKEFDYGADAVIMHG---------ATPDELEPIVAAYRA
Mvan_2018|M.vanbaalenii_PYR-1 TGSPQQCADRVRQELDYGADAVIMHG---------ATPDELEPIVAAYRA
MSMEG_2249|M.smegmatis_MC2_155 TGSAQQCVARIRKEFDYGADAVIMHG---------ATPDELEPIVAEYRA
TH_1627|M.thermoresistible__bu TGSARQCVERIRKEFDYGADAVIMHG---------ATPDELEPIVAEYRA
MAV_1607|M.avium_104 TGSAQQCVARIRQEFDYGADAVILHG---------ATPDELEPIVAAYRA
MMAR_4003|M.marinum_M TGSAQQCVDRIRAEFGYGADAVIMHG---------ATPDELEPVVAAYRQ
MUL_3866|M.ulcerans_Agy99 TGSAQQCVDRIRAEFGYGADAVIMHG---------ATPDELEPVVAAYRQ
Mb2975c|M.bovis_AF2122/97 -GTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRG
Rv2951c|M.tuberculosis_H37Rv -GTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRG
MLBr_00131|M.leprae_Br4923 -GTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRG
MAB_2053|M.abscessus_ATCC_1997 EGVLDHIVLYSPSIGLAPERIAENLG---------SLIRDCAPAFAGGKG
* . . * :
Mflv_4328|M.gilvum_PYR-GCK GQS-
Mvan_2018|M.vanbaalenii_PYR-1 GRS-
MSMEG_2249|M.smegmatis_MC2_155 TR--
TH_1627|M.thermoresistible__bu VVG-
MAV_1607|M.avium_104 G---
MMAR_4003|M.marinum_M KAQ-
MUL_3866|M.ulcerans_Agy99 KAQ-
Mb2975c|M.bovis_AF2122/97 LKKL
Rv2951c|M.tuberculosis_H37Rv LKKL
MLBr_00131|M.leprae_Br4923 LKKL
MAB_2053|M.abscessus_ATCC_1997 DQSG