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TELHVRRPRFDFTADVPWQWNPASPAFSYFMNATSIIAVCFEQMIVAAVTEARPLISDPSVAEEATAFLR QEAQHSASHRKHVNALIAHYPGLQHTVDATMAEFDALTASTPLAYRLAYIADLEATFTPSFKLMLDNEAS LFRPGDERVASLFLWHFVEEVEHRSSALVIYDAVIGDPWYRLRKVPAVVRHLLGVIAVIAEGVNTHIPES DRAVDARTMHPWHGTRTALRQRISRDRHTAPPAFAGVPRTQKLIAGWRVLLSQLPFHDPADEPLPGFADE WFARWERGEDVTRWYSSRRAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4095 | - | - | 100% (302) | hypothetical protein Mflv_4095 |
| M. gilvum PYR-GCK | Mflv_3010 | - | 4e-89 | 55.12% (303) | hypothetical protein Mflv_3010 |
| M. gilvum PYR-GCK | Mflv_3425 | - | 6e-13 | 27.47% (233) | hypothetical protein Mflv_3425 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 2e-08 | 23.96% (192) | hypothetical protein Mb2799c |
| M. tuberculosis H37Rv | Rv2777c | - | 2e-08 | 23.96% (192) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4764c | - | 8e-92 | 53.92% (306) | hypothetical protein MAB_4764c |
| M. marinum M | MMAR_2810 | - | 4e-91 | 53.47% (303) | hypothetical protein MMAR_2810 |
| M. avium 104 | MAV_4121 | - | 2e-10 | 24.66% (223) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2108 | - | 3e-92 | 55.78% (303) | hypothetical protein MSMEG_2108 |
| M. thermoresistible (build 8) | TH_1630 | - | 1e-103 | 59.06% (298) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2157 | - | 1e-08 | 25.73% (206) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_3497 | - | 1e-89 | 55.12% (303) | hypothetical protein Mvan_3497 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4095|M.gilvum_PYR-GCK --------------------------------------------------
TH_1630|M.thermoresistible__bu --------------------------------------------------
MAB_4764c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2810|M.marinum_M --------------------------------------------------
MSMEG_2108|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3497|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_4121|M.avium_104 --------------------------------------------------
Mflv_4095|M.gilvum_PYR-GCK ---------------------MTELHVRRPRFDFTAD-VPWQWNPASPAF
TH_1630|M.thermoresistible__bu ---------------------MTELRIRRIRFDFDET-VPFNWNTANPAF
MAB_4764c|M.abscessus_ATCC_199 ---------------------MTELIVRKLRFAFADHHVPFLWNESNPAF
MMAR_2810|M.marinum_M ---------------------MTDLIVRKMRFAFADHYVPFLWNEKNPAF
MSMEG_2108|M.smegmatis_MC2_155 ---------------------MTDLIVRKMRFAFADHHVPFLWNEANPAF
Mvan_3497|M.vanbaalenii_PYR-1 ---------------------MTELIVRKLRFAFANHHVPFLWNEDNPAF
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MAV_4121|M.avium_104 -MFTVDDKATGPHDA---ALDHERIVLQARDVDFDWSALPFYYVPGEPFT
: :. . * :*: : .*
Mflv_4095|M.gilvum_PYR-GCK SYFMNATSIIAVCFEQMIVAAVTEARPLISDPSVAEEATAFLRQEAQHSA
TH_1630|M.thermoresistible__bu STYMNMVSIMAICFEKMLVAAVREAMPLITDPAVAEEADAFLRQEAQHAG
MAB_4764c|M.abscessus_ATCC_199 SSMANAVSFLAIAFEKMIGQMIPEAMPLIADPVIAEEADAFVRQEGQHSM
MMAR_2810|M.marinum_M SSMANAVSFLAIAFEKMVVSMISEAKPMITDPAIAEEADAFVRQEGQHSM
MSMEG_2108|M.smegmatis_MC2_155 SSMANAVSFLAIAFEKMIGHMITEAMPHITDPEIAEEAQAFVRQEGQHSM
Mvan_3497|M.vanbaalenii_PYR-1 SAMANAVSFLAVGFEKMIGGMIPEAMPHITDPAVAEEADAFVRQEGQHSM
Mb2799c|M.bovis_AF2122/97 THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
Rv2777c|M.tuberculosis_H37Rv THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MUL_2157|M.ulcerans_Agy99 THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MAV_4121|M.avium_104 THFCNVLHLLLPAGEEFIVEAFKDTLPLIKDDQLRRDVQGFISQEAMHSQ
: * :: *::. . .: * * * : :. .*: **. *:
Mflv_4095|M.gilvum_PYR-GCK SHRKHVNALIAHYPGLQHTVDATMAEFDALTASTP----------LAYRL
TH_1630|M.thermoresistible__bu AHRRHVRALIRSHPGLQQTLDAAIGAYDQLTETTS----------LRHRL
MAB_4764c|M.abscessus_ATCC_199 GHRQHAKGLIKSYPGLKETLDEVIASFDDLTANKP----------LKYRL
MMAR_2810|M.marinum_M AHRQHARGLIKSYPALKETLDEVIAAFDDLTASKP----------LKYRL
MSMEG_2108|M.smegmatis_MC2_155 AHRQHAKGLIKSYPALKETLAEVVKAFDDLTADTP----------LKYRL
Mvan_3497|M.vanbaalenii_PYR-1 AHRQHVKGLIKAYPGLKGTLDKVIDSYDEMTASTP----------LKYRL
Mb2799c|M.bovis_AF2122/97 AHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQV
Rv2777c|M.tuberculosis_H37Rv AHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQV
MUL_2157|M.ulcerans_Agy99 AHSGVLAHFEAQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWLLEQV
MAV_4121|M.avium_104 AHAGVLGHFAAKGIDVTPFTDQMRWLFGQLIGDRPRWSPRRRQSWLLERV
.* : : : : . * ::
Mflv_4095|M.gilvum_PYR-GCK AYIADLEATFTPSFKLMLDNEASLFRPGDERVASLFLWHFVEEVEHRSSA
TH_1630|M.thermoresistible__bu AYVADLEAAFTPFFTMLLDHEAALFRPGDDRVASLFVWHFVEEIEHRSSA
MAB_4764c|M.abscessus_ATCC_199 AYTADLEATFTPVFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
MMAR_2810|M.marinum_M AYTADLEATFTPAFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
MSMEG_2108|M.smegmatis_MC2_155 AYTADLEATFTPVFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
Mvan_3497|M.vanbaalenii_PYR-1 AYTADLEATFTPVFKLMLDHDDTLFATGDDRVASLFLWHFVEEVEHRSSA
Mb2799c|M.bovis_AF2122/97 SFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVA
Rv2777c|M.tuberculosis_H37Rv SFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVA
MUL_2157|M.ulcerans_Agy99 SFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKAVA
MAV_4121|M.avium_104 SMVAALEHYTAILGEWILDTPQHDALGTDPVMLDLLRWHGAEEVEHKAVA
: * :* : :*: * : .:: ** .**:**:: *
Mflv_4095|M.gilvum_PYR-GCK LVIYDAVIGDPWYRLRKVPAVVRHLLGVIAVIAEGVNTHIPESDRAVDAR
TH_1630|M.thermoresistible__bu LLIYDAVVGDKWYRMRALPRIVRHLMHVVLLITNGINEHVPPADRAIDTS
MAB_4764c|M.abscessus_ATCC_199 LIIYDAVVNDPWYRMRMAPSIFRHVWSVLRIACEGFNKHVPLEDRKVDAL
MMAR_2810|M.marinum_M LIIYDAVADDPWYRMRVAPSIFKHVWSVLQIACHGFNKHVPVEERKVDAL
MSMEG_2108|M.smegmatis_MC2_155 LIIYDAVVDDPWYRMRVAPSVFKHVWGVLRLACEGFNKHVPVSERGVDAM
Mvan_3497|M.vanbaalenii_PYR-1 LIIYDAVVDDPWYRMRVAPSIFKHVMGIIRMVSEEFNEHVPLSERKVDAM
Mb2799c|M.bovis_AF2122/97 FDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTKPR
Rv2777c|M.tuberculosis_H37Rv FDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTKPR
MUL_2157|M.ulcerans_Agy99 FDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPGTKPR
MAV_4121|M.avium_104 FDTMKHLRAGYWRQVRTQLLVTPALLWLFIRGVRFMYSVDPHLPPGSKPR
: . : . * ::* : : : . . * ..
Mflv_4095|M.gilvum_PYR-GCK TMHPWHGTRTALRQRI----SRDRHTAPPAFAGVPRTQKLIAGWRVLLSQ
TH_1630|M.thermoresistible__bu TIIPLY--RLVHRTRK----DPDMPGVRPALHPVPWRQKLLTAWRVLGSQ
MAB_4764c|M.abscessus_ATCC_199 SMFGMQARKKSLLQRLPFVDAPNDGPIENAFRHLPAREVMVAMSGAVRSQ
MMAR_2810|M.marinum_M SMFGMQRQKKALMQRLPFFDVADDGPLGNAFGHLPWREQLIAMFGVVRSQ
MSMEG_2108|M.smegmatis_MC2_155 SMFGMQARRKKLMQRLPFLAAPDDGPIANAFGHLPVRDMLVALVGVVRSQ
Mvan_3497|M.vanbaalenii_PYR-1 STFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLTALSGVVRSQ
Mb2799c|M.bovis_AF2122/97 ---------------------WRDYFKAARRGLVPGLPRLLRVVGHY--Y
Rv2777c|M.tuberculosis_H37Rv ---------------------WRDYFKAARRGLVPGLPRLLRVVGHY--Y
MUL_2157|M.ulcerans_Agy99 ---------------------WRDYVRSARRGLTPGPWRLIRVVGDY--Y
MAV_4121|M.avium_104 ---------------------WRDYFSAARRGLVPGPFEFLRVIGAY--Y
* :
Mflv_4095|M.gilvum_PYR-GCK LPFHDPADEPLPGFADEWFARWERGEDVTRWYSSRRAG-----
TH_1630|M.thermoresistible__bu TPMHNPAHAVIPAFADDWIARYDRGDDVSHGYTS---------
MAB_4764c|M.abscessus_ATCC_199 IPGHNPAHEKLPALADEWFARYEAGYEVTQWYTAGKATGVGV-
MMAR_2810|M.marinum_M IPGHNPAHENLPALADEWFKRYAAGYDVTQWYTAPVQQLARDR
MSMEG_2108|M.smegmatis_MC2_155 IPGHDPAHEKLPALADEWFARYETGYDVTQWYTAGEKADVANV
Mvan_3497|M.vanbaalenii_PYR-1 IPGHDPAHEELPALAQQWFDRYEAGYDVTRWYTATESESANV-
Mb2799c|M.bovis_AF2122/97 KPGFHPSQLGGLGAAVDYLAVSPAARASH--------------
Rv2777c|M.tuberculosis_H37Rv KPGFHPSQLGGLGAAVDYLAVSPAARASH--------------
MUL_2157|M.ulcerans_Agy99 KPGFHPSQLGGLERAVDYLAVSPAARASH--------------
MAV_4121|M.avium_104 TPGFHPSQLGGVGRAVDYLARSPAARAAH--------------
* ..*:. * ::: .