For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGAAMVSVDDRATGPHSSESRAAD HERLVLEPRDVEFDWTNLPFHYVPNEPMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGF IGQEAMHSQAHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQVSFIAAIEHYTA VMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIR GVRFMYSVDPYLPPGTKPRWRDYFKAARRGLVPGLPRLLRVVGHYYKPGFHPSQLGGLGAAVDYLAVSPA ARASH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2777c | - | - | 100% (356) | hypothetical protein Rv2777c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 0.0 | 100.00% (356) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_3425 | - | 8e-55 | 39.59% (293) | hypothetical protein Mflv_3425 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0089c | - | 7e-56 | 38.16% (283) | hypothetical protein MAB_0089c |
| M. marinum M | MMAR_1931 | - | 1e-156 | 85.57% (305) | hypothetical protein MMAR_1931 |
| M. avium 104 | MAV_4121 | - | 1e-138 | 74.75% (305) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3675 | - | 7e-51 | 36.99% (292) | metal-dependent hydrolase |
| M. thermoresistible (build 8) | TH_2221 | - | 6e-53 | 38.43% (281) | metal-dependent hydrolase |
| M. ulcerans Agy99 | MUL_2157 | - | 1e-156 | 85.57% (305) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_3179 | - | 2e-53 | 39.02% (287) | hypothetical protein Mvan_3179 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MMAR_1931|M.marinum_M --------------------------------------------------
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_4121|M.avium_104 --------------------------------------------------
Mflv_3425|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3179|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2221|M.thermoresistible__bu --------------------------------------------------
MSMEG_3675|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0089c|M.abscessus_ATCC_199 --------------------------------------------------
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
MMAR_1931|M.marinum_M -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MAV_4121|M.avium_104 -MFTVDDKATGPHD---AALDHERIVLQARDVDFDWSALPFYYVPGEPFT
Mflv_3425|M.gilvum_PYR-GCK -MLRPRRFSA--------EVDPGPVQIQARKVHFDVSDVPLHWIPGHPVA
Mvan_3179|M.vanbaalenii_PYR-1 -MLRPRRFDA--------EIDPGPVQIQARKVHFDVADVPLHWIPGHPVA
TH_2221|M.thermoresistible__bu -MLRPRRFAT--------EVDPGPVQIQARQVHFDVSGIPLHWIPGHPVA
MSMEG_3675|M.smegmatis_MC2_155 -MLRPLRFDH--------EIDPGPVQIQARKVHFDLSDIPLHWIPGHPVA
MAB_0089c|M.abscessus_ATCC_199 -MVRNTTDTTGVQV---VPTEPGEVVLRPRNVQFDTSHTPLHWIPNEPIV
*. : : :..*.*.** : *::::*..*.
Rv2777c|M.tuberculosis_H37Rv THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
Mb2799c|M.bovis_AF2122/97 THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MMAR_1931|M.marinum_M THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MUL_2157|M.ulcerans_Agy99 THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MAV_4121|M.avium_104 THFCNVLHLLLPAGEEFIVEAFKDTLPLIKDDQLRRDVQGFISQEAMHSQ
Mflv_3425|M.gilvum_PYR-GCK SHVVSVLNILLPAGERWFVETFNEALPLVKDPKLADDIRGFIGQEATHAD
Mvan_3179|M.vanbaalenii_PYR-1 SHVVSVLNIVLPAGERWFVQTFNEALPLVKDPKLADDIRGFIGQEATHAD
TH_2221|M.thermoresistible__bu SNLISLLNVVLPDAERWFVATFNEALPYVKDPKLADDMRGFIGQEATHAD
MSMEG_3675|M.smegmatis_MC2_155 STMVNLFNVVLPVAEHWFVDTFNEALPYVRDPKLADDMRGFIGQEATHAE
MAB_0089c|M.abscessus_ATCC_199 SHFISAFNLLLPEGERAFVDTFTRALPYVKDDKIREAMIGFMGQEAVHAE
: . . ::::** .*. :* .*. :** ::* :: : **:.*** *::
Rv2777c|M.tuberculosis_H37Rv AHSGVVDHFDAQ-GVDVTAFTNQIRWLFEKLLGE-SPRRSPRRQYSWLLE
Mb2799c|M.bovis_AF2122/97 AHSGVVDHFDAQ-GVDVTAFTNQIRWLFEKLLGE-SPRRSPRRQYSWLLE
MMAR_1931|M.marinum_M AHSGVLAHFEAQ-GVDVTPYTDQIRWLFGKLLAE-KPGRNPRQRHRWLLE
MUL_2157|M.ulcerans_Agy99 AHSGVLAHFEAQ-GVDVTPYTDQIRWLFGKLLAE-KPGRNPRQRHRWLLE
MAV_4121|M.avium_104 AHAGVLGHFAAK-GIDVTPFTDQMRWLFGQLIGD-RPRWSPRRRQSWLLE
Mflv_3425|M.gilvum_PYR-GCK VHDQVLHDVMVRHGVDPAPILGQVDHLFGKSLAPLDDSADEARRLNHLCD
Mvan_3179|M.vanbaalenii_PYR-1 VHDQVLHEFMVSHGVNPAPILAQIEHMFTGVLAPPDETVDESRRWSHLCD
TH_2221|M.thermoresistible__bu VHEQVMYDFMVEHGVNPEPILAQIEYMFTKVLTP-STSSDPKRRFNNLCE
MSMEG_3675|M.smegmatis_MC2_155 THDKVLEEFLTAHDVHYQPILELVDHVFNTMLAP-KPATDPRRRLNDLCD
MAB_0089c|M.abscessus_ATCC_199 THHKVLGDFLEKNGLDVRPALTQIEYIT-HMLERTNELRSEKLRYRVMVE
.* *: .. .:. . : : : . : : :
Rv2777c|M.tuberculosis_H37Rv QVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKA
Mb2799c|M.bovis_AF2122/97 QVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKA
MMAR_1931|M.marinum_M QVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKA
MUL_2157|M.ulcerans_Agy99 QVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKA
MAV_4121|M.avium_104 RVSMVAALEHYTAILGEWILDTPQHDALGTDPVMLDLLRWHGAEEVEHKA
Mflv_3425|M.gilvum_PYR-GCK RLWLIAAIEHYTAVMGDFALNCT-WDDHGADPTLVDLFRWHGSEEVEHRS
Mvan_3179|M.vanbaalenii_PYR-1 RLWLIAAIEHYTAVMGDFALNCT-WDDHGADPTLVDLFRWHGSEEVEHRS
TH_2221|M.thermoresistible__bu RLWLIAALEHYTAVLGDFALNCR-WDDHGAHPTMVDLYRWHGAEEVEHRN
MSMEG_3675|M.smegmatis_MC2_155 RLWLIAAIEHYTAVLGDFVLNCA-WDDHHADPTLTDLFRWHGAEEVEHRS
MAB_0089c|M.abscessus_ATCC_199 KLALIAGIEHFTAVLGDWVLNHP-FEKFNADPEMVDLFRWHGAEEVEHRS
:: ::*.:**:**::*:: *: : :.* : *: ****:*****:
Rv2777c|M.tuberculosis_H37Rv VAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYL-PPGT
Mb2799c|M.bovis_AF2122/97 VAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYL-PPGT
MMAR_1931|M.marinum_M VAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLL-APGT
MUL_2157|M.ulcerans_Agy99 VAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLL-APGT
MAV_4121|M.avium_104 VAFDTMKHLRAGYWRQVRTQLLVTPALLWLFIRGVRFMYSVDPHL-PPGS
Mflv_3425|M.gilvum_PYR-GCK VAHDVAVYFHDSYFARIRAMTIAASMLFVFFQRVAWYLTSTDPSV-DASW
Mvan_3179|M.vanbaalenii_PYR-1 VAHDVAMYFHDSYLARIRAMSVAATMLFVFFQRTAWYLVKHDPGV-DANW
TH_2221|M.thermoresistible__bu VAHDVAVYFRDSYVDRIRAMCIAMPLMWAFFERGMWYLVKTDPSV-ELSW
MSMEG_3675|M.smegmatis_MC2_155 VAHDVAVYFQDSYLARVRAMTIAATAVYMFFQRGTWAMIRKDPTV-DIGW
MAB_0089c|M.abscessus_ATCC_199 VAYDVARYFQIRRGHMMLTFVLATMLLVGVMLRYTKFLVRQDPSLPNYGV
**.*. ::: : : . : . * : ** : .
Rv2777c|M.tuberculosis_H37Rv KPRWRDYFKAARRGLVPGLPRLL-RVVGHYYKPGFHPSQLGGLGAAVDYL
Mb2799c|M.bovis_AF2122/97 KPRWRDYFKAARRGLVPGLPRLL-RVVGHYYKPGFHPSQLGGLGAAVDYL
MMAR_1931|M.marinum_M KPRWRDYVRSARRGLTPGPWRLI-RVVGDYYKPGFHPSQLGGLERAVDYL
MUL_2157|M.ulcerans_Agy99 KPRWRDYVRSARRGLTPGPWRLI-RVVGDYYKPGFHPSQLGGLERAVDYL
MAV_4121|M.avium_104 KPRWRDYFSAARRGLVPGPFEFL-RVIGAYYTPGFHPSQLGGVGRAVDYL
Mflv_3425|M.gilvum_PYR-GCK WKFNRMRMRDSKLGLLPLYRRLFGANTLSYFRPGYSPEQLGSTAQAVAYL
Mvan_3179|M.vanbaalenii_PYR-1 WAFNRMRMRDSKLGLLPKYRKLFGSSTLGYFRPGYAPEQLGSTAQAVAYL
TH_2221|M.thermoresistible__bu WQTQRQRCRDSGLGLLPKWRTLFFTNTLDYFRPGFTPEQMGSTAQAVAYL
MSMEG_3675|M.smegmatis_MC2_155 WKMHRLRMRDSKLGLLPKFSTLFGTNTLAYCRPSFTPDQMGSTAQAVAYL
MAB_0089c|M.abscessus_ATCC_199 FGVLRQMNKAMKRGAFLRWRELG-KSALEFMRPGFSPDQVGSTAQAVAYL
* * : : *.: *.*:*. ** **
Rv2777c|M.tuberculosis_H37Rv AVSPAARASH--
Mb2799c|M.bovis_AF2122/97 AVSPAARASH--
MMAR_1931|M.marinum_M AVSPAARASH--
MUL_2157|M.ulcerans_Agy99 AVSPAARASH--
MAV_4121|M.avium_104 ARSPAARAAH--
Mflv_3425|M.gilvum_PYR-GCK AASPAARAAHL-
Mvan_3179|M.vanbaalenii_PYR-1 ASSPAARAAHL-
TH_2221|M.thermoresistible__bu ASSPAARSARL-
MSMEG_3675|M.smegmatis_MC2_155 ASSPAARAAHL-
MAB_0089c|M.abscessus_ATCC_199 STSPAAKAAAGY
: ****:::