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TELIVRKLRFAFASAPVPFVWNQANPAFSSMANAVSFLAVGFEKMIGSMIPEAMPHITDRGVAEEADAFV RQEGQHAMAHRQHVKGLIRSYPGLKGTLDKVIAAYDDMTANTPLKYRLAYTADLEATFTPVFKLMLDHDD TLFSTGDDRVASLFLWHFVEEVEHRSSALTIYDAVVDDPWYRMRVARSIFTHVMAIIRLVSEEFNEHVPL ADREVDAMSTFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLVALGGVVRSQIPGHDPAHEKLP ALAQEWFDRYEAGYDVTRWYTASQESETARV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3010 | - | - | 100% (312) | hypothetical protein Mflv_3010 |
| M. gilvum PYR-GCK | Mflv_4095 | - | 4e-89 | 55.12% (303) | hypothetical protein Mflv_4095 |
| M. gilvum PYR-GCK | Mflv_4629 | - | 3e-09 | 28.48% (158) | metal-dependent hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 2e-05 | 21.18% (203) | hypothetical protein Mb2799c |
| M. tuberculosis H37Rv | Rv2777c | - | 2e-05 | 21.18% (203) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4764c | - | 1e-142 | 78.36% (305) | hypothetical protein MAB_4764c |
| M. marinum M | MMAR_2810 | - | 1e-135 | 74.92% (303) | hypothetical protein MMAR_2810 |
| M. avium 104 | MAV_3671 | - | 2e-05 | 22.95% (183) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2108 | - | 1e-142 | 76.60% (312) | hypothetical protein MSMEG_2108 |
| M. thermoresistible (build 8) | TH_1630 | - | 2e-86 | 53.95% (304) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2157 | - | 1e-05 | 22.33% (206) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_3497 | - | 1e-162 | 88.78% (312) | hypothetical protein Mvan_3497 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3010|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3497|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4764c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2810|M.marinum_M --------------------------------------------------
MSMEG_2108|M.smegmatis_MC2_155 --------------------------------------------------
TH_1630|M.thermoresistible__bu --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_3671|M.avium_104 --------------------------------------------------
Mflv_3010|M.gilvum_PYR-GCK ---------------------MTELIVRKLRFAFASAPVPFVWNQANPAF
Mvan_3497|M.vanbaalenii_PYR-1 ---------------------MTELIVRKLRFAFANHHVPFLWNEDNPAF
MAB_4764c|M.abscessus_ATCC_199 ---------------------MTELIVRKLRFAFADHHVPFLWNESNPAF
MMAR_2810|M.marinum_M ---------------------MTDLIVRKMRFAFADHYVPFLWNEKNPAF
MSMEG_2108|M.smegmatis_MC2_155 ---------------------MTDLIVRKMRFAFADHHVPFLWNEANPAF
TH_1630|M.thermoresistible__bu ---------------------MTELRIRRIRFDFDET-VPFNWNTANPAF
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MAV_3671|M.avium_104 -MVIIDNQAAGPHDAS---VDHERLVLEARDVDFDWAQLPFHYAPGEPFA
* :. . * :** : :*
Mflv_3010|M.gilvum_PYR-GCK SSMANAVSFLAVGFEKMIGSMIPEAMPHITDRGVAEEADAFVRQEGQHAM
Mvan_3497|M.vanbaalenii_PYR-1 SAMANAVSFLAVGFEKMIGGMIPEAMPHITDPAVAEEADAFVRQEGQHSM
MAB_4764c|M.abscessus_ATCC_199 SSMANAVSFLAIAFEKMIGQMIPEAMPLIADPVIAEEADAFVRQEGQHSM
MMAR_2810|M.marinum_M SSMANAVSFLAIAFEKMVVSMISEAKPMITDPAIAEEADAFVRQEGQHSM
MSMEG_2108|M.smegmatis_MC2_155 SSMANAVSFLAIAFEKMIGHMITEAMPHITDPEIAEEAQAFVRQEGQHSM
TH_1630|M.thermoresistible__bu STYMNMVSIMAICFEKMLVAAVREAMPLITDPAVAEEADAFLRQEAQHAG
Mb2799c|M.bovis_AF2122/97 THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
Rv2777c|M.tuberculosis_H37Rv THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MUL_2157|M.ulcerans_Agy99 THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MAV_3671|M.avium_104 THVLNVLHLLLPAGEQFFVEVFKQALPLIRDDQLRLDVQGFIGQEGVHSR
: * : :: *::. . :: * * * : :.:.*: **. *:
Mflv_3010|M.gilvum_PYR-GCK AHRQHVKGLIRSYPGLKGTLDKVIAAYDDMTANTP----------LKYRL
Mvan_3497|M.vanbaalenii_PYR-1 AHRQHVKGLIKAYPGLKGTLDKVIDSYDEMTASTP----------LKYRL
MAB_4764c|M.abscessus_ATCC_199 GHRQHAKGLIKSYPGLKETLDEVIASFDDLTANKP----------LKYRL
MMAR_2810|M.marinum_M AHRQHARGLIKSYPALKETLDEVIAAFDDLTASKP----------LKYRL
MSMEG_2108|M.smegmatis_MC2_155 AHRQHAKGLIKSYPALKETLAEVVKAFDDLTADTP----------LKYRL
TH_1630|M.thermoresistible__bu AHRRHVRALIRSHPGLQQTLDAAIGAYDQLTETTS----------LRHRL
Mb2799c|M.bovis_AF2122/97 AHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQV
Rv2777c|M.tuberculosis_H37Rv AHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQV
MUL_2157|M.ulcerans_Agy99 AHSGVLAHFEAQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWLLEQV
MAV_3671|M.avium_104 AHANVLAHFAARGIDLRPYTGQIEWLFGTLLGPRPNWSPRRRQSWLLEQI
.* : : : : . * ::
Mflv_3010|M.gilvum_PYR-GCK AYTADLEATFTPVFKLMLDHDDTLFSTGDDRVASLFLWHFVEEVEHRSSA
Mvan_3497|M.vanbaalenii_PYR-1 AYTADLEATFTPVFKLMLDHDDTLFATGDDRVASLFLWHFVEEVEHRSSA
MAB_4764c|M.abscessus_ATCC_199 AYTADLEATFTPVFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
MMAR_2810|M.marinum_M AYTADLEATFTPAFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
MSMEG_2108|M.smegmatis_MC2_155 AYTADLEATFTPVFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
TH_1630|M.thermoresistible__bu AYVADLEAAFTPFFTMLLDHEAALFRPGDDRVASLFVWHFVEEIEHRSSA
Mb2799c|M.bovis_AF2122/97 SFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVA
Rv2777c|M.tuberculosis_H37Rv SFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVA
MUL_2157|M.ulcerans_Agy99 SFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKAVA
MAV_3671|M.avium_104 SLVSAIEHYTAILGEWILDSPAHDRIGTDPVMLDMLRWHGAEEVEHKAVA
: : :* : :*: * : .:: ** .**:**:: *
Mflv_3010|M.gilvum_PYR-GCK LTIYDAVVDDPWYRMRVARSIFTHVMAIIRLVSEEFNEHVPLADREVDAM
Mvan_3497|M.vanbaalenii_PYR-1 LIIYDAVVDDPWYRMRVAPSIFKHVMGIIRMVSEEFNEHVPLSERKVDAM
MAB_4764c|M.abscessus_ATCC_199 LIIYDAVVNDPWYRMRMAPSIFRHVWSVLRIACEGFNKHVPLEDRKVDAL
MMAR_2810|M.marinum_M LIIYDAVADDPWYRMRVAPSIFKHVWSVLQIACHGFNKHVPVEERKVDAL
MSMEG_2108|M.smegmatis_MC2_155 LIIYDAVVDDPWYRMRVAPSVFKHVWGVLRLACEGFNKHVPVSERGVDAM
TH_1630|M.thermoresistible__bu LLIYDAVVGDKWYRMRALPRIVRHLMHVVLLITNGINEHVPPADRAIDTS
Mb2799c|M.bovis_AF2122/97 FDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLP------
Rv2777c|M.tuberculosis_H37Rv FDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLP------
MUL_2157|M.ulcerans_Agy99 FDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLA------
MAV_3671|M.avium_104 FDTMKHLRAGYWRQVRTQLVVTPAMLLLWIRGVRFMYSRDPYLP------
: . : . * ::* : : : . : *
Mflv_3010|M.gilvum_PYR-GCK STFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLVALGGVVRSQ
Mvan_3497|M.vanbaalenii_PYR-1 STFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLTALSGVVRSQ
MAB_4764c|M.abscessus_ATCC_199 SMFGMQARKKSLLQRLPFVDAPNDGPIENAFRHLPAREVMVAMSGAVRSQ
MMAR_2810|M.marinum_M SMFGMQRQKKALMQRLPFFDVADDGPLGNAFGHLPWREQLIAMFGVVRSQ
MSMEG_2108|M.smegmatis_MC2_155 SMFGMQARRKKLMQRLPFLAAPDDGPIANAFGHLPVRDMLVALVGVVRSQ
TH_1630|M.thermoresistible__bu TIIPLYR----LVHRT--RKDPDMPGVRPALHPVPWRQKLLTAWRVLGSQ
Mb2799c|M.bovis_AF2122/97 ---------------------PGTKPRWRDYFKAARRGLVPGLPRLLRVV
Rv2777c|M.tuberculosis_H37Rv ---------------------PGTKPRWRDYFKAARRGLVPGLPRLLRVV
MUL_2157|M.ulcerans_Agy99 ---------------------PGTKPRWRDYVRSARRGLTPGPWRLIRVV
MAV_3671|M.avium_104 ---------------------PHTKPRWRDYFRAAWRGLVPGPLRFVRAV
. . * :
Mflv_3010|M.gilvum_PYR-GCK IPGHDPAHEKLPALAQEWFDRYEAGYDVTRWYTASQESETARV
Mvan_3497|M.vanbaalenii_PYR-1 IPGHDPAHEELPALAQQWFDRYEAGYDVTRWYTAT-ESESANV
MAB_4764c|M.abscessus_ATCC_199 IPGHNPAHEKLPALADEWFARYEAGYEVTQWYTAGKATGVGV-
MMAR_2810|M.marinum_M IPGHNPAHENLPALADEWFKRYAAGYDVTQWYTAPVQQLARDR
MSMEG_2108|M.smegmatis_MC2_155 IPGHDPAHEKLPALADEWFARYETGYDVTQWYTAGEKADVANV
TH_1630|M.thermoresistible__bu TPMHNPAHAVIPAFADDWIARYDRGDDVSHGYTS---------
Mb2799c|M.bovis_AF2122/97 GHYYKPGFHPSQLGGLGAAVDYLAVSPAARASH----------
Rv2777c|M.tuberculosis_H37Rv GHYYKPGFHPSQLGGLGAAVDYLAVSPAARASH----------
MUL_2157|M.ulcerans_Agy99 GDYYKPGFHPSQLGGLERAVDYLAVSPAARASH----------
MAV_3671|M.avium_104 ANYYRPGFHPSQLGGLQRAVDYLAVSPAARASH----------
: *.. . * .::