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VTELIVRKLRFAFANHHVPFLWNEDNPAFSAMANAVSFLAVGFEKMIGGMIPEAMPHITDPAVAEEADAF VRQEGQHSMAHRQHVKGLIKAYPGLKGTLDKVIDSYDEMTASTPLKYRLAYTADLEATFTPVFKLMLDHD DTLFATGDDRVASLFLWHFVEEVEHRSSALIIYDAVVDDPWYRMRVAPSIFKHVMGIIRMVSEEFNEHVP LSERKVDAMSTFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLTALSGVVRSQIPGHDPAHEEL PALAQQWFDRYEAGYDVTRWYTATESESANV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3497 | - | - | 100% (311) | hypothetical protein Mvan_3497 |
| M. vanbaalenii PYR-1 | Mvan_0314 | - | 2e-09 | 29.14% (151) | metal-dependent hydrolase |
| M. vanbaalenii PYR-1 | Mvan_3179 | - | 3e-08 | 28.02% (182) | hypothetical protein Mvan_3179 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 2e-05 | 22.41% (174) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_3010 | - | 1e-162 | 88.78% (312) | hypothetical protein Mflv_3010 |
| M. tuberculosis H37Rv | Rv2777c | - | 2e-05 | 22.41% (174) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4764c | - | 1e-145 | 78.14% (311) | hypothetical protein MAB_4764c |
| M. marinum M | MMAR_2810 | - | 1e-140 | 76.38% (309) | hypothetical protein MMAR_2810 |
| M. avium 104 | MAV_4121 | - | 6e-05 | 24.70% (166) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2108 | - | 1e-145 | 78.53% (312) | hypothetical protein MSMEG_2108 |
| M. thermoresistible (build 8) | TH_1630 | - | 1e-85 | 51.97% (304) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2157 | - | 3e-05 | 23.16% (177) | hypothetical protein MUL_2157 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3497|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3010|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4764c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2810|M.marinum_M --------------------------------------------------
MSMEG_2108|M.smegmatis_MC2_155 --------------------------------------------------
TH_1630|M.thermoresistible__bu --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_4121|M.avium_104 --------------------------------------------------
Mvan_3497|M.vanbaalenii_PYR-1 ---------------------MTELIVRKLRFAFANHHVPFLWNEDNPAF
Mflv_3010|M.gilvum_PYR-GCK ---------------------MTELIVRKLRFAFASAPVPFVWNQANPAF
MAB_4764c|M.abscessus_ATCC_199 ---------------------MTELIVRKLRFAFADHHVPFLWNESNPAF
MMAR_2810|M.marinum_M ---------------------MTDLIVRKMRFAFADHYVPFLWNEKNPAF
MSMEG_2108|M.smegmatis_MC2_155 ---------------------MTDLIVRKMRFAFADHHVPFLWNEANPAF
TH_1630|M.thermoresistible__bu ---------------------MTELRIRRIRFDFDET-VPFNWNTANPAF
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MAV_4121|M.avium_104 -MFTVDDKATGPHDA---ALDHERIVLQARDVDFDWSALPFYYVPGEPFT
: :. . * :** : :*
Mvan_3497|M.vanbaalenii_PYR-1 SAMANAVSFLAVGFEKMIGGMIPEAMPHITDPAVAEEADAFVRQEGQHSM
Mflv_3010|M.gilvum_PYR-GCK SSMANAVSFLAVGFEKMIGSMIPEAMPHITDRGVAEEADAFVRQEGQHAM
MAB_4764c|M.abscessus_ATCC_199 SSMANAVSFLAIAFEKMIGQMIPEAMPLIADPVIAEEADAFVRQEGQHSM
MMAR_2810|M.marinum_M SSMANAVSFLAIAFEKMVVSMISEAKPMITDPAIAEEADAFVRQEGQHSM
MSMEG_2108|M.smegmatis_MC2_155 SSMANAVSFLAIAFEKMIGHMITEAMPHITDPEIAEEAQAFVRQEGQHSM
TH_1630|M.thermoresistible__bu STYMNMVSIMAICFEKMLVAAVREAMPLITDPAVAEEADAFLRQEAQHAG
Mb2799c|M.bovis_AF2122/97 THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
Rv2777c|M.tuberculosis_H37Rv THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MUL_2157|M.ulcerans_Agy99 THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MAV_4121|M.avium_104 THFCNVLHLLLPAGEEFIVEAFKDTLPLIKDDQLRRDVQGFISQEAMHSQ
: * : :: *::. . .: * * * : :.:.*: **. *:
Mvan_3497|M.vanbaalenii_PYR-1 AHRQHVKGLIKAYPGLKGTLDKVIDSYDEMTASTP----------LKYRL
Mflv_3010|M.gilvum_PYR-GCK AHRQHVKGLIRSYPGLKGTLDKVIAAYDDMTANTP----------LKYRL
MAB_4764c|M.abscessus_ATCC_199 GHRQHAKGLIKSYPGLKETLDEVIASFDDLTANKP----------LKYRL
MMAR_2810|M.marinum_M AHRQHARGLIKSYPALKETLDEVIAAFDDLTASKP----------LKYRL
MSMEG_2108|M.smegmatis_MC2_155 AHRQHAKGLIKSYPALKETLAEVVKAFDDLTADTP----------LKYRL
TH_1630|M.thermoresistible__bu AHRRHVRALIRSHPGLQQTLDAAIGAYDQLTETTS----------LRHRL
Mb2799c|M.bovis_AF2122/97 AHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQV
Rv2777c|M.tuberculosis_H37Rv AHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQV
MUL_2157|M.ulcerans_Agy99 AHSGVLAHFEAQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWLLEQV
MAV_4121|M.avium_104 AHAGVLGHFAAKGIDVTPFTDQMRWLFGQLIGDRPRWSPRRRQSWLLERV
.* : : : .: . * ::
Mvan_3497|M.vanbaalenii_PYR-1 AYTADLEATFTPVFKLMLDHDDTLFATGDDRVASLFLWHFVEEVEHRSSA
Mflv_3010|M.gilvum_PYR-GCK AYTADLEATFTPVFKLMLDHDDTLFSTGDDRVASLFLWHFVEEVEHRSSA
MAB_4764c|M.abscessus_ATCC_199 AYTADLEATFTPVFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
MMAR_2810|M.marinum_M AYTADLEATFTPAFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
MSMEG_2108|M.smegmatis_MC2_155 AYTADLEATFTPVFKLMLDHDDTLFAPGDDRVASLFLWHFVEEVEHRSSA
TH_1630|M.thermoresistible__bu AYVADLEAAFTPFFTMLLDHEAALFRPGDDRVASLFVWHFVEEIEHRSSA
Mb2799c|M.bovis_AF2122/97 SFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVA
Rv2777c|M.tuberculosis_H37Rv SFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVA
MUL_2157|M.ulcerans_Agy99 SFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKAVA
MAV_4121|M.avium_104 SMVAALEHYTAILGEWILDTPQHDALGTDPVMLDLLRWHGAEEVEHKAVA
: * :* : :*: * : .:: ** .**:**:: *
Mvan_3497|M.vanbaalenii_PYR-1 LIIYDAVVDDPWYRMRVAPSIFKHVMGIIRMVSEEFNEHVPLSERKVDAM
Mflv_3010|M.gilvum_PYR-GCK LTIYDAVVDDPWYRMRVARSIFTHVMAIIRLVSEEFNEHVPLADREVDAM
MAB_4764c|M.abscessus_ATCC_199 LIIYDAVVNDPWYRMRMAPSIFRHVWSVLRIACEGFNKHVPLEDRKVDAL
MMAR_2810|M.marinum_M LIIYDAVADDPWYRMRVAPSIFKHVWSVLQIACHGFNKHVPVEERKVDAL
MSMEG_2108|M.smegmatis_MC2_155 LIIYDAVVDDPWYRMRVAPSVFKHVWGVLRLACEGFNKHVPVSERGVDAM
TH_1630|M.thermoresistible__bu LLIYDAVVGDKWYRMRALPRIVRHLMHVVLLITNGINEHVPPADRAIDTS
Mb2799c|M.bovis_AF2122/97 FDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTKPR
Rv2777c|M.tuberculosis_H37Rv FDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTKPR
MUL_2157|M.ulcerans_Agy99 FDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPGTKPR
MAV_4121|M.avium_104 FDTMKHLRAGYWRQVRTQLLVTPALLWLFIRGVRFMYSVDPHLPPGSKPR
: . : . * ::* : : : . : * ..
Mvan_3497|M.vanbaalenii_PYR-1 STFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLTALSGVVRSQ
Mflv_3010|M.gilvum_PYR-GCK STFRIHRRKKALLQRLPFVDAPYDGPFANAFSHLPLREQLVALGGVVRSQ
MAB_4764c|M.abscessus_ATCC_199 SMFGMQARKKSLLQRLPFVDAPNDGPIENAFRHLPAREVMVAMSGAVRSQ
MMAR_2810|M.marinum_M SMFGMQRQKKALMQRLPFFDVADDGPLGNAFGHLPWREQLIAMFGVVRSQ
MSMEG_2108|M.smegmatis_MC2_155 SMFGMQARRKKLMQRLPFLAAPDDGPIANAFGHLPVRDMLVALVGVVRSQ
TH_1630|M.thermoresistible__bu TIIPLYR----LVHRT--RKDPDMPGVRPALHPVPWRQKLLTAWRVLGSQ
Mb2799c|M.bovis_AF2122/97 --------------WRDYFKAARRG-------LVPGLPRLLRVVGHY--Y
Rv2777c|M.tuberculosis_H37Rv --------------WRDYFKAARRG-------LVPGLPRLLRVVGHY--Y
MUL_2157|M.ulcerans_Agy99 --------------WRDYVRSARRG-------LTPGPWRLIRVVGDY--Y
MAV_4121|M.avium_104 --------------WRDYFSAARRG-------LVPGPFEFLRVIGAY--Y
. * :
Mvan_3497|M.vanbaalenii_PYR-1 IPGHDPAHEELPALAQQWFDRYEAGYDVTRWYTAT-ESESANV
Mflv_3010|M.gilvum_PYR-GCK IPGHDPAHEKLPALAQEWFDRYEAGYDVTRWYTASQESETARV
MAB_4764c|M.abscessus_ATCC_199 IPGHNPAHEKLPALADEWFARYEAGYEVTQWYTAGKATGVGV-
MMAR_2810|M.marinum_M IPGHNPAHENLPALADEWFKRYAAGYDVTQWYTAPVQQLARDR
MSMEG_2108|M.smegmatis_MC2_155 IPGHDPAHEKLPALADEWFARYETGYDVTQWYTAGEKADVANV
TH_1630|M.thermoresistible__bu TPMHNPAHAVIPAFADDWIARYDRGDDVSHGYTS---------
Mb2799c|M.bovis_AF2122/97 KPGFHPSQLGGLGAAVDYLAVSPAARASH--------------
Rv2777c|M.tuberculosis_H37Rv KPGFHPSQLGGLGAAVDYLAVSPAARASH--------------
MUL_2157|M.ulcerans_Agy99 KPGFHPSQLGGLERAVDYLAVSPAARASH--------------
MAV_4121|M.avium_104 TPGFHPSQLGGVGRAVDYLARSPAARAAH--------------
* ..*:: * ::: .