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MRANDKTTIQPRMLRRALDFMHENAQYDITIRDIASAADVTPRAIQYAFREHLDTTPLEYLRRIRLERAH RELMSADPSFDTVTSIAGRCGFSHPGRFSSAYKQVFGTEPSRTLRSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3905 | - | - | 100% (118) | helix-turn-helix domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0731 | - | 5e-32 | 50.88% (114) | helix-turn-helix domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0534 | - | 4e-21 | 39.32% (117) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 7e-08 | 28.85% (104) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3833 | - | 7e-08 | 28.85% (104) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2899c | - | 6e-08 | 26.80% (97) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 1e-06 | 36.51% (63) | transcriptional regulatory protein |
| M. avium 104 | MAV_4063 | - | 3e-29 | 53.33% (105) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_2260 | - | 1e-15 | 38.39% (112) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3937 | - | 2e-32 | 57.55% (106) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | MUL_2902 | - | 3e-06 | 36.51% (63) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0118 | - | 4e-30 | 50.88% (114) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3905|M.gilvum_PYR-GCK --------------------------------------------------
TH_3937|M.thermoresistible__bu ---------------VSDDTMVATAERQGPIT-----------------R
Mvan_0118|M.vanbaalenii_PYR-1 ---------------MHTATIDTATAPYAPRD-----------------D
MAV_4063|M.avium_104 --MGLTTMTVRDDGAPVGAPAEAARSDYGPVDPVLAVNGERRARPVAVEY
MSMEG_2260|M.smegmatis_MC2_155 --MSRLTRLGFIDIRRTSDPVRRKVRSRGVPP--------------ALAD
Mb3863|M.bovis_AF2122/97 --------------------------------------------------
Rv3833|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2855|M.marinum_M -------------------------------------------------M
MUL_2902|M.ulcerans_Agy99 -------------------------------------------------M
MAB_2899c|M.abscessus_ATCC_199 MRSARGPHSGEPGRSGEPHSGRLGRSGEPHSGRLGRSGEPHSGRLGRSGE
Mflv_3905|M.gilvum_PYR-GCK --------------------------------------------------
TH_3937|M.thermoresistible__bu SRTELTDPSEVGDFLEAVYGVRVSRVRPPRSHDGPLLTHVRADAGSFIVD
Mvan_0118|M.vanbaalenii_PYR-1 LHFESDDLDATEDFLVRAY-TKMSISAEDGERASALID--RRWLGPVSYD
MAV_4063|M.avium_104 KQFRGADAQSARRFFATAYDPGWRIAG---VTNHCVVSHRRSDTGSMTVD
MSMEG_2260|M.smegmatis_MC2_155 HEIFYTEDVREAARLVGRTLSPLTLTVDAADAGGFAATMHGVRLRNVSLL
Mb3863|M.bovis_AF2122/97 -----------------------------MSENSHHRLATTSLTLPPG--
Rv3833|M.tuberculosis_H37Rv -----------------------------MSENSHHRLATTSLTLPPG--
MMAR_2855|M.marinum_M ARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVATG
MUL_2902|M.ulcerans_Agy99 ARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDERPVATG
MAB_2899c|M.abscessus_ATCC_199 PHSVVVLALPGTIGFDLATAVEVFR-RVYLADGSRPYLVRVCGTEPVVSA
Mflv_3905|M.gilvum_PYR-GCK --------------------------------------------------
TH_3937|M.thermoresistible__bu RLHIAGELHTTADPIHKVVTLWPTSGRVVGRCAG-LEGRAGAGEIILSGQ
Mvan_0118|M.vanbaalenii_PYR-1 ELRLDFHMSYDAAPLGRICLCRVHEGCIEEDFIGEPQDVFVPGDVALLSP
MAV_4063|M.avium_104 EVAIQGRMTLEIPAGDTVVVIQPRAGALN--VAG---GPLATPDFPLLVA
MSMEG_2260|M.smegmatis_MC2_155 YLDLHVAATLDIPESGRYFAVHMPLNGSATVTHPAAEFDAGTTRSLVTSP
Mb3863|M.bovis_AF2122/97 -------ARIERHRHPSHQIVYPSAG-------------AVSVTTHAGTW
Rv3833|M.tuberculosis_H37Rv -------ARIERHRHPSHQIVYPSAG-------------AVSVTTHAGTW
MMAR_2855|M.marinum_M IGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTARR
MUL_2902|M.ulcerans_Agy99 IGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAAAGTARR
MAB_2899c|M.abscessus_ATCC_199 GPFGIATDLGLEAVSEAETIVVPARDNPTAPLP-EGVLDALRGAYERGTR
Mflv_3905|M.gilvum_PYR-GCK --------------------------------------------------
TH_3937|M.thermoresistible__bu PDLVRQTHCDDLAATVILLDPALVAHVASGSAGDDAAAAIRFASLRPAVG
Mvan_0118|M.vanbaalenii_PYR-1 PELPYSGRVCEASYDLTMFDTALLDRVATPDRGR-SAGSVRLLGHRPVSP
MAV_4063|M.avium_104 HGMACVLHCHGARFDVVTIAAEVLQKVA-AEWHTALSQQTQFLNWRPRSR
MSMEG_2260|M.smegmatis_MC2_155 GDPVRMSFAHDSPQMLVRIEEEAMNAHLTRLLGRNLVGPLKFEPEFDLTT
Mb3863|M.bovis_AF2122/97 ITPVNRAIWIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNP
Rv3833|M.tuberculosis_H37Rv ITPVNRAIWIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNP
MMAR_2855|M.marinum_M VVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRS
MUL_2902|M.ulcerans_Agy99 VVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPDPIFIRS
MAB_2899c|M.abscessus_ATCC_199 IASICAGAFTLAEAGILDGKRATTHWLAADLFRERYPAVHLDADVLYVDE
Mflv_3905|M.gilvum_PYR-GCK ----------------MMRANDKTT-------------------------
TH_3937|M.thermoresistible__bu ATRLWQD-TVRYVRDHVLVDDTRATP-LVVGQAARLLAAVTASAFPN-SA
Mvan_0118|M.vanbaalenii_PYR-1 EAQLQLNSAIECVRTVVHSDGPAPTR-LVASTTASMIAAVVLSAFPTNAA
MAV_4063|M.avium_104 AAVRAWHRALDYAMLTLASPDTARQP-LIAAGMAGLLAGALLECYPS--N
MSMEG_2260|M.smegmatis_MC2_155 EAATRWHAAVQLIHTEVYHAGSLVQRGCAIGPVEELAMSSLLYLQPSTYY
Mb3863|M.bovis_AF2122/97 LMRELIIACSQA--------------DRTDTDEHHRMLAVLQDQLPT--T
Rv3833|M.tuberculosis_H37Rv LMRELVIACSQA--------------DRTDTDEHHRMLAVLQDQLPT--T
MMAR_2855|M.marinum_M SPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPGGQ--T
MUL_2902|M.ulcerans_Agy99 SPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRRPCGQ--T
MAB_2899c|M.abscessus_ATCC_199 G-QVLTSAGAAAGLDLCLHIVARDHGAAVAAEAARVAVAPLHRDGGQ--A
Mflv_3905|M.gilvum_PYR-GCK ----------IQPRMLRRALDFMHENAQYDITIRDIASAADVTPRAIQYA
TH_3937|M.thermoresistible__bu AEPAGQTVNGQRPPLLRRALDYIDANAAADISLADIAAAVHVTPRALQYM
Mvan_0118|M.vanbaalenii_PYR-1 SEPTALDRIDAKPPLLRRATAYIEGNADADIALADIAGSVHVTPRALQYM
MAV_4063|M.avium_104 LTEQDPVSDLALPETLKEAVSFIHRHAAEDIGINDVAAAVHLTPRAVQYL
MSMEG_2260|M.smegmatis_MC2_155 SDITRPTPATPRRAVIQQAVDYIEDHLAEKITMESLAEALHMSVRSIQQG
Mb3863|M.bovis_AF2122/97 SIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQRTLSRL
Rv3833|M.tuberculosis_H37Rv SIREPLWVPSPTDRRLRHACALIADNLTQPLTLQQIGGRIGVSQRTLSRL
MMAR_2855|M.marinum_M QFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPRHFTRV
MUL_2902|M.ulcerans_Agy99 QFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPRHFTRV
MAB_2899c|M.abscessus_ATCC_199 QYVIRN--RRRAEVSLGEILAWIEHNAHRELSLEDLATEASTSVRSLNRR
: : : : .:. : * .
Mflv_3905|M.gilvum_PYR-GCK FREHLDTTPLEYLRRIRLERAHRELMSADPSF-DTVTSIAGRCGFSHPGR
TH_3937|M.thermoresistible__bu FRRHLQTTPLQYLRRIRLHRAHHDLLAQTPAS-DTVGAIAARWGFAHAGR
Mvan_0118|M.vanbaalenii_PYR-1 FRKYLDMTPMEYLRRVRMDHAHRELIKADAGQ-TTVQIVAARWGFAHTGR
MAV_4063|M.avium_104 FRRQLDTTPTEYMRRVRLSRAHQELVAATTAS-STVTEIAQRWGFAHTGR
MSMEG_2260|M.smegmatis_MC2_155 FRTELGMSPTTFIRERRLERVREELTDAIPSDGVTVTAVAERWGFHHLGS
Mb3863|M.bovis_AF2122/97 FSDELGMTFPQWRTQLRLQHALVLLA----ERHD-VTSVASECGWATPSA
Rv3833|M.tuberculosis_H37Rv FSDELGMTFPQWRTQLRLQHALVLLA----ERHD-VTSVASECGWATPSA
MMAR_2855|M.marinum_M FTGEVGEAPRQYVERVRTEAARRQLE----ETEDTVVAIAARCGFGTAET
MUL_2902|M.ulcerans_Agy99 FTGEVGEAPGRYVERVRTEAARRQLE----ETEDTVVAIAARCGFGTAET
MAB_2899c|M.abscessus_ATCC_199 FRAETGQTPMQWLTGVRVRHAQQLLE----RSADSVEWIGREVGFGSPAN
* : : * . * * :. . *:
Mflv_3905|M.gilvum_PYR-GCK FSSAYKQVFGTEPSRTLRSS---------------
TH_3937|M.thermoresistible__bu FAMQYRQTYGRSPHQTLRG----------------
Mvan_0118|M.vanbaalenii_PYR-1 FAAMYREAYGRNPSDTLRS----------------
MAV_4063|M.avium_104 FAVLYRQTYGQSPHTTLRQQTAV------------
MSMEG_2260|M.smegmatis_MC2_155 FAVEYRKRWGETPSETLRR----------------
Mb3863|M.bovis_AF2122/97 FIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv FIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
MMAR_2855|M.marinum_M MRRNFIRRVGISPDQYRKAFA--------------
MUL_2902|M.ulcerans_Agy99 MRRNFIRRVGISPDQYRKAFA--------------
MAB_2899c|M.abscessus_ATCC_199 FREQFRRLTGVSPLAYRNTFRAQSA----------
: : . * * .